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Search results 201 to 300 out of 2731 for Akt1

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Type Details Score
Publication
First Author: Larson-Casey JL
Year: 2021
Journal: FASEB J
Title: Post-translational regulation of PGC-1α modulates fibrotic repair.
Volume: 35
Issue: 6
Pages: e21675
Publication
First Author: Subbotina E
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Musclin is an activity-stimulated myokine that enhances physical endurance.
Volume: 112
Issue: 52
Pages: 16042-7
Publication
First Author: Bancroft T
Year: 2015
Journal: J Biol Chem
Title: Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function.
Volume: 290
Issue: 1
Pages: 409-22
Publication
First Author: Protack CD
Year: 2017
Journal: Sci Rep
Title: Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency.
Volume: 7
Issue: 1
Pages: 15386
Publication
First Author: Mogi M
Year: 2003
Journal: J Biol Chem
Title: Akt signaling regulates side population cell phenotype via Bcrp1 translocation.
Volume: 278
Issue: 40
Pages: 39068-75
Publication
First Author: Mathew B
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury.
Volume: 309
Issue: 12
Pages: L1420-9
Publication
First Author: Wang B
Year: 2016
Journal: Aging Cell
Title: CYP2J2 and its metabolites (epoxyeicosatrienoic acids) attenuate cardiac hypertrophy by activating AMPKα2 and enhancing nuclear translocation of Akt1.
Volume: 15
Issue: 5
Pages: 940-52
Publication
First Author: Toda G
Year: 2020
Journal: Mol Cell
Title: Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.
Volume: 79
Issue: 1
Pages: 43-53.e4
Publication
First Author: Hung CM
Year: 2014
Journal: Cell Rep
Title: Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Volume: 8
Issue: 1
Pages: 256-71
Publication
First Author: Ju R
Year: 2014
Journal: J Biol Chem
Title: Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.
Volume: 289
Issue: 1
Pages: 510-9
Publication
First Author: Yang ZZ
Year: 2005
Journal: Mol Cell Biol
Title: Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice.
Volume: 25
Issue: 23
Pages: 10407-18
Publication
First Author: Jin SY
Year: 2014
Journal: Biochim Biophys Acta
Title: Insulin regulates monocyte trans-endothelial migration through surface expression of macrophage-1 antigen.
Volume: 1842
Issue: 9
Pages: 1539-48
Publication  
First Author: Chen YW
Year: 2011
Journal: Neuroscience
Title: Behavioral phenotyping of v-akt murine thymoma viral oncogene homolog 1-deficient mice reveals a sex-specific prepulse inhibition deficit in females that can be partially alleviated by glycogen synthase kinase-3 inhibitors but not by antipsychotics.
Volume: 174
Pages: 178-89
Publication
First Author: Xin X
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Akt activation and augmented fibronectin production in hyperhexosemia.
Volume: 293
Issue: 4
Pages: E1036-44
Publication
First Author: Wei Y
Year: 2013
Journal: Circulation
Title: The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis.
Volume: 127
Issue: 15
Pages: 1609-19
Publication
First Author: Baek HJ
Year: 2018
Journal: Int J Biol Sci
Title: Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors.
Volume: 14
Issue: 13
Pages: 1769-1781
Publication
First Author: Abdalla M
Year: 2015
Journal: Br J Pharmacol
Title: The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis.
Volume: 172
Issue: 16
Pages: 4173-88
Publication
First Author: Wang Y
Year: 2011
Journal: Cancer Res
Title: The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.
Volume: 71
Issue: 2
Pages: 371-82
Publication
First Author: Jin Y
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Opposing Actions of AKT (Protein Kinase B) Isoforms in Vascular Smooth Muscle Injury and Therapeutic Response.
Volume: 37
Issue: 12
Pages: 2311-2321
Publication
First Author: Yin H
Year: 2008
Journal: Blood
Title: The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation.
Volume: 111
Issue: 2
Pages: 658-65
Publication
First Author: Ackah E
Year: 2005
Journal: J Clin Invest
Title: Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis.
Volume: 115
Issue: 8
Pages: 2119-27
Publication
First Author: DeBosch B
Year: 2006
Journal: J Biol Chem
Title: Akt2 regulates cardiac metabolism and cardiomyocyte survival.
Volume: 281
Issue: 43
Pages: 32841-51
Publication
First Author: Dickey CA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Akt and CHIP coregulate tau degradation through coordinated interactions.
Volume: 105
Issue: 9
Pages: 3622-7
Publication
First Author: Chen J
Year: 2010
Journal: Blood
Title: Akt isoforms differentially regulate neutrophil functions.
Volume: 115
Issue: 21
Pages: 4237-46
Publication
First Author: Endersby R
Year: 2011
Journal: Cancer Res
Title: Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.
Volume: 71
Issue: 12
Pages: 4106-16
Publication
First Author: Shiojima I
Year: 2002
Journal: J Biol Chem
Title: Akt signaling mediates postnatal heart growth in response to insulin and nutritional status.
Volume: 277
Issue: 40
Pages: 37670-7
Publication
First Author: Ikeda H
Year: 2011
Journal: Mol Cell Biol
Title: Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice.
Volume: 31
Issue: 5
Pages: 1054-65
Publication
First Author: Gleason CE
Year: 2010
Journal: Mol Endocrinol
Title: Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth.
Volume: 24
Issue: 1
Pages: 178-92
Publication  
First Author: Nguyen TD
Year: 2023
Journal: Front Cardiovasc Med
Title: Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.
Volume: 10
Pages: 1279868
Publication
First Author: Creamer BA
Year: 2010
Journal: Mol Cell Biol
Title: Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.
Volume: 30
Issue: 12
Pages: 2957-70
Publication
First Author: Maruyama S
Year: 2011
Journal: J Biol Chem
Title: Adiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanism.
Volume: 286
Issue: 37
Pages: 32790-800
Publication
First Author: Yang KC
Year: 2012
Journal: J Mol Cell Cardiol
Title: Exercise training and PI3Kα-induced electrical remodeling is independent of cellular hypertrophy and Akt signaling.
Volume: 53
Issue: 4
Pages: 532-41
Publication
First Author: Li G
Year: 2008
Journal: J Neurochem
Title: Activation and membrane binding of retinal protein kinase Balpha/Akt1 is regulated through light-dependent generation of phosphoinositides.
Volume: 107
Issue: 5
Pages: 1382-97
Publication
First Author: Xu Y
Year: 2014
Journal: Biochem Biophys Res Commun
Title: DNA-PKcs-SIN1 complexation mediates low-dose X-ray irradiation (LDI)-induced Akt activation and osteoblast differentiation.
Volume: 453
Issue: 3
Pages: 362-7
Publication
First Author: Lindner HB
Year: 2011
Journal: PLoS One
Title: Anti-bacterial effects of poly-N-acetyl-glucosamine nanofibers in cutaneous wound healing: requirement for Akt1.
Volume: 6
Issue: 4
Pages: e18996
Publication
First Author: Wang J
Year: 2019
Journal: Cell Stem Cell
Title: Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis.
Volume: 25
Issue: 6
Pages: 754-767.e9
Allele
Name: thymoma viral proto-oncogene 1; targeted mutation 1, Nissim Hay
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Cenni V
Year: 2011
Journal: Mol Biol Cell
Title: Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2).
Volume: 22
Issue: 16
Pages: 2946-56
Publication
First Author: Xu J
Year: 2002
Journal: J Biol Chem
Title: The role of Asp-462 in regulating Akt activity.
Volume: 277
Issue: 38
Pages: 35561-6
Publication
First Author: Zacharioudaki V
Year: 2009
Journal: J Immunol
Title: Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression.
Volume: 182
Issue: 10
Pages: 6444-51
Publication
First Author: Babaev VR
Year: 2014
Journal: J Lipid Res
Title: Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice.
Volume: 55
Issue: 11
Pages: 2296-308
Publication
First Author: Ouchi N
Year: 2008
Journal: J Biol Chem
Title: Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism.
Volume: 283
Issue: 47
Pages: 32802-11
Publication
First Author: Wang Y
Year: 2007
Journal: Am J Respir Cell Mol Biol
Title: The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival.
Volume: 36
Issue: 1
Pages: 68-77
Publication
First Author: Woulfe D
Year: 2004
Journal: J Clin Invest
Title: Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2.
Volume: 113
Issue: 3
Pages: 441-50
Publication
First Author: Lu M
Year: 2012
Journal: Nat Med
Title: Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
Volume: 18
Issue: 3
Pages: 388-95
Publication
First Author: Pauta M
Year: 2016
Journal: Hepatology
Title: Akt-mediated foxo1 inhibition is required for liver regeneration.
Volume: 63
Issue: 5
Pages: 1660-74
Publication
First Author: Iliopoulos D
Year: 2009
Journal: Sci Signal
Title: MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.
Volume: 2
Issue: 92
Pages: ra62
Publication
First Author: Goncalves MD
Year: 2010
Journal: PLoS One
Title: Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition.
Volume: 5
Issue: 9
Pages: e12707
Publication
First Author: Koral K
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Akt recruits Dab2 to albumin endocytosis in the proximal tubule.
Volume: 307
Issue: 12
Pages: F1380-9
Publication
First Author: Polytarchou C
Year: 2011
Journal: Cancer Res
Title: Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.
Volume: 71
Issue: 13
Pages: 4720-31
Publication
First Author: Levenga J
Year: 2021
Journal: Cereb Cortex Commun
Title: Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease.
Volume: 2
Issue: 2
Pages: tgab036
Publication
First Author: Tu Q
Year: 2011
Journal: J Biol Chem
Title: Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1.
Volume: 286
Issue: 14
Pages: 12542-53
Publication
First Author: Brand Y
Year: 2015
Journal: PLoS One
Title: All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.
Volume: 10
Issue: 3
Pages: e0121599
Publication
First Author: Zhou F
Year: 2010
Journal: Am J Pathol
Title: Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development.
Volume: 177
Issue: 4
Pages: 2124-33
Publication
First Author: Youn HS
Year: 2017
Journal: Sci Rep
Title: Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.
Volume: 7
Issue: 1
Pages: 5198
Publication
First Author: Khattar E
Year: 2012
Journal: FEBS J
Title: Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylation.
Volume: 279
Issue: 7
Pages: 1220-30
Publication
First Author: Bechard M
Year: 2009
Journal: Mol Cell Biol
Title: Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal.
Volume: 29
Issue: 8
Pages: 2092-104
Publication
First Author: Naeem AS
Year: 2015
Journal: Cell Death Differ
Title: AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation.
Volume: 22
Issue: 12
Pages: 2123-32
Publication
First Author: Easton RM
Year: 2005
Journal: Mol Cell Biol
Title: Role for Akt3/protein kinase Bgamma in attainment of normal brain size.
Volume: 25
Issue: 5
Pages: 1869-78
Publication
First Author: Li G
Year: 2007
Journal: J Neurosci
Title: Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death.
Volume: 27
Issue: 1
Pages: 203-11
Publication  
First Author: Riehle C
Year: 2020
Journal: JCI Insight
Title: Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling.
Volume: 5
Issue: 6
Publication
First Author: Dummler B
Year: 2006
Journal: Mol Cell Biol
Title: Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies.
Volume: 26
Issue: 21
Pages: 8042-51
Publication  
First Author: Cho KM
Year: 2019
Journal: Front Immunol
Title: Mst1-Deficiency Induces Hyperactivation of Monocyte-Derived Dendritic Cells via Akt1/c-myc Pathway.
Volume: 10
Pages: 2142
Publication
First Author: Delogu S
Year: 2015
Journal: Oncotarget
Title: SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice.
Volume: 6
Issue: 4
Pages: 2222-34
Publication
First Author: Babaev VR
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.
Volume: 39
Issue: 2
Pages: 156-169
Publication  
First Author: Zhu Z
Year: 2019
Journal: Life Sci Alliance
Title: The AKT isoforms 1 and 2 drive B cell fate decisions during the germinal center response.
Volume: 2
Issue: 6
Publication
First Author: Rastogi R
Year: 2013
Journal: J Biol Chem
Title: Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
Volume: 288
Issue: 47
Pages: 33966-77
Publication
First Author: Lee IH
Year: 2007
Journal: J Biol Chem
Title: Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2.
Volume: 282
Issue: 41
Pages: 29866-73
Publication
First Author: Minhajuddin M
Year: 2009
Journal: J Biol Chem
Title: Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.
Volume: 284
Issue: 7
Pages: 4052-61
Publication
First Author: Wang H
Year: 2011
Journal: J Immunol
Title: The role of glycogen synthase kinase 3 in regulating IFN-β-mediated IL-10 production.
Volume: 186
Issue: 2
Pages: 675-84
Publication
First Author: Zhou H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes.
Volume: 112
Issue: 38
Pages: 11864-9
Publication
First Author: Kerr BA
Year: 2013
Journal: Sci Signal
Title: Interference with akt signaling protects against myocardial infarction and death by limiting the consequences of oxidative stress.
Volume: 6
Issue: 287
Pages: ra67
Publication
First Author: Chatterjee S
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS.
Volume: 302
Issue: 1
Pages: H105-14
Publication
First Author: Chen WS
Year: 2009
Journal: Mol Cell Biol
Title: Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.
Volume: 29
Issue: 11
Pages: 3151-62
Publication
First Author: Ock S
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts.
Volume: 1864
Issue: 4 Pt A
Pages: 1183-1191
Publication
First Author: Schmidt JW
Year: 2014
Journal: Mol Cell Biol
Title: Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
Volume: 34
Issue: 7
Pages: 1363-77
Publication
First Author: La Torre A
Year: 2015
Journal: Stem Cells
Title: The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells.
Volume: 33
Issue: 9
Pages: 2674-85
Publication
First Author: Guha M
Year: 2010
Journal: Biochim Biophys Acta
Title: Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.
Volume: 1797
Issue: 6-7
Pages: 1055-65
Publication
First Author: Zhou X
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Inhibitory phosphorylation of GSK-3β by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP).
Volume: 304
Issue: 7
Pages: F908-17
Publication
First Author: Linnerth-Petrik NM
Year: 2014
Journal: PLoS One
Title: Opposing functions of Akt isoforms in lung tumor initiation and progression.
Volume: 9
Issue: 4
Pages: e94595
Publication
First Author: Tang H
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.
Volume: 308
Issue: 2
Pages: L208-20
Publication
First Author: Hayakawa-Yano Y
Year: 2007
Journal: Stem Cells
Title: Epidermal growth factor signaling mediated by grb2 associated binder1 is required for the spatiotemporally regulated proliferation of olig2-expressing progenitors in the embryonic spinal cord.
Volume: 25
Issue: 6
Pages: 1410-22
Publication
First Author: Ishigaki S
Year: 2010
Journal: Cell Death Differ
Title: AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Volume: 17
Issue: 5
Pages: 774-86
Publication
First Author: Hegedus B
Year: 2007
Journal: Cell Stem Cell
Title: Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms.
Volume: 1
Issue: 4
Pages: 443-57
Protein
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 14  
Fragment?: true
Publication
First Author: Chen CC
Year: 2012
Journal: Genes Dev
Title: Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.
Volume: 26
Issue: 19
Pages: 2154-68
Publication
First Author: Di-Poï N
Year: 2005
Journal: Mol Cell Biol
Title: Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.
Volume: 25
Issue: 5
Pages: 1696-712
Publication
First Author: Lange A
Year: 2009
Journal: Nature
Title: Integrin-linked kinase is an adaptor with essential functions during mouse development.
Volume: 461
Issue: 7266
Pages: 1002-6
Publication
First Author: Staal SP
Year: 1988
Journal: Genomics
Title: The AKT1 proto-oncogene maps to human chromosome 14, band q32.
Volume: 2
Issue: 1
Pages: 96-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory