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Search results 201 to 236 out of 236 for Amfr

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Type Details Score
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase AMFR
Type: chain
End: 643
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Protein
H3BJC0
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
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Allele
Amfr<em1Smoc> | MGI:7288246
Name: autocrine motility factor receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Sun L (2023)
Description: Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to promote pneumonia.
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Publication
12650607 | -
First Author: Onishi Y
Year: 2003
Journal: Clin Exp Metastasis
Title: Overexpression of autocrine motility factor receptor (AMFR) in NIH3T3 fibroblasts induces cell transformation.
Volume: 20
Issue: 1
Pages: 51-8
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Publication
16987818 | -
First Author: Ballar P
Year: 2006
Journal: J Biol Chem
Title: The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation.
Volume: 281
Issue: 46
Pages: 35359-68
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Publication
18216283 | -
First Author: Morito D
Year: 2008
Journal: Mol Biol Cell
Title: Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.
Volume: 19
Issue: 4
Pages: 1328-36
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Strain
MGI:6474760 | C57BL/6JSmoc-Amfr<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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DO Term
DOID:0070458 | hereditary spastic paraplegia 89
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GO Term
GO:0000836 | Hrd1p ubiquitin ligase complex
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Protein Coding Gene
MGI:2145496 | Fam8a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19223579 | J:248234
First Author: Li W
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2.
Volume: 106
Issue: 10
Pages: 3722-7
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Publication
19560420 | -
First Author: Das R
Year: 2009
Journal: Mol Cell
Title: Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Volume: 34
Issue: 6
Pages: 674-85
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Publication
23942235 | -
First Author: Das R
Year: 2013
Journal: EMBO J
Title: Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Volume: 32
Issue: 18
Pages: 2504-16
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Protein Domain
IPR040675 | AMFR_Ube2g2-bd
Type: Domain
Description: The activity of RING finger ubiquitin ligases (E3) is dependent on their ability to facilitate transfer of ubiquitin from ubiquitin-conjugating enzymes (E2) to substrates. The G2BR domain within the E3 ubiquitin-protein ligase AMFR (also known as gp78) binds selectively and with high affinity to the E2 Ube2g2. Binding to the G2BR results in conformational changes in Ube2g2 that affect ubiquitin loading. The Ube2g2-G2BR interaction also causes a 50-fold increase in affinity between the E2 and RING finger. Hence, the Ube2g2-binding region (G2BR) is required for the function of gp78. In yeast, Ubc7p, the ortholog of Ube2g2, is recruited by Cue1p to the ER membrane. Cue1p directly binds Ubc7p through a stretch of 50 aa domain analogous to G2BR, i.e. suggesting that this domain which activates ERAD and Hrd1p stimulating ubiquitylation, might be the yeast equivalent of the G2BR domain [, , ].
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Publication
16249333 | J:102925
First Author: Li G
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome.
Volume: 102
Issue: 44
Pages: 15809-14
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Publication
17875708 | J:124844
First Author: Yanagawa T
Year: 2007
Journal: Cancer Res
Title: Regulation of phosphoglucose isomerase/autocrine motility factor activities by the poly(ADP-ribose) polymerase family-14.
Volume: 67
Issue: 18
Pages: 8682-9
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Publication
31247458 | J:280586
 
First Author: Burghard AL
Year: 2019
Journal: Neurobiol Aging
Title: Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing.
Volume: 81
Pages: 47-57
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Publication
16563432 | J:112336
First Author: Haga A
Year: 2006
Journal: J Mol Biol
Title: The autocrine motility factor (AMF) and AMF-receptor combination needs sugar chain recognition ability and interaction using the C-terminal region of AMF.
Volume: 358
Issue: 3
Pages: 741-53
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Protein
Q3TCI2
Organism: Mus musculus/domesticus
Length: 639  
Fragment?: false
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Protein
Q3U007
Organism: Mus musculus/domesticus
Length: 643  
Fragment?: false
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Publication
17114649 | J:187362
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
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Publication
19144319 | J:143718
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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