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Search results 201 to 262 out of 262 for Arih2

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Hits by Pathway

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691447
Age: postnatal adult
Image: UC Davis_1877256
Specimen Label: UC Davis_1877256
Detected: true
Specimen Num: 160
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691447
Age: postnatal adult
Image: UC Davis_1877266
Specimen Label: UC Davis_1877266
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691447
Age: postnatal adult
Image: UC Davis_1877267
Specimen Label: UC Davis_1877267
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691447
Age: postnatal adult
Image: UC Davis_1877168
Specimen Label: UC Davis_1877168
Detected: true
Specimen Num: 84
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691447
Age: postnatal adult
Image: UC Davis_1877169
Specimen Label: UC Davis_1877169
Detected: true
Specimen Num: 85
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Publication
10422847 | J:66295
First Author: van der Reijden BA
Year: 1999
Journal: Protein Sci
Title: TRIADs: a new class of proteins with a novel cysteine-rich signature.
Volume: 8
Issue: 7
Pages: 1557-61
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Publication
22819825 | J:188492
First Author: Bae S
Year: 2012
Journal: FEBS Lett
Title: TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
Volume: 586
Issue: 19
Pages: 3057-63
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Gene
704645 | LOC704645
Type: gene
Organism: macaque, rhesus
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Gene
709672 | LOC709672
Type: gene
Organism: macaque, rhesus
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Publication
19256485 | J:148999
First Author: Plafker KS
Year: 2009
Journal: Biochemistry
Title: The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases.
Volume: 48
Issue: 15
Pages: 3527-37
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase ARIH2
Type: chain
End: 492
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Publication
25028400 | -
 
First Author: Berger T
Year: 2013
Journal: Cold Spring Harb Symp Quant Biol
Title: Dissection of signaling in inflammation: three novel inflammatory regulators.
Volume: 78
Pages: 141-7
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Publication
19340006 | -
First Author: Marteijn JA
Year: 2009
Journal: Leukemia
Title: The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.
Volume: 23
Issue: 8
Pages: 1480-9
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Publication
23213454 | -
First Author: Hassink G
Year: 2012
Journal: Biol Open
Title: Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport.
Volume: 1
Issue: 6
Pages: 607-14
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Publication
25895533 | -
First Author: Wang H
Year: 2015
Journal: J Immunol
Title: HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1.
Volume: 194
Issue: 11
Pages: 5375-87
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Protein Domain
IPR031126 | Ariadne-2
Type: Family
Description: Ariadne-2 (ARIH2, Triad1) is a member of the RBR (RING-in-between-RING) family of E3 ligases. It contains a TRIAD motif that harbours 2 RING finger structures. Triad1/ARIH2 catalyses the formation of different poly-ubiquitin chains, which can mark proteins for proteasomal degradation or serve non-proteolytic functions []. It binds the E2 ubiquitin-conjugating enzymes UbcH7 and Ubc13, and this interaction plays a major role in myelopoiesis [, ]. During myeloid differentiation its transcription is activated by HoxA10, a transcription factor []. It is also a regulator of endosomal transport [].Triad1/ARIH2 is involved in regulating the inflammatory response [, ]. ARIH2 physically binds to newly synthesised nuclear hypophosphorylated IkBb and facilitates its ubiquitination and proteasomal degradation. Nuclear hypophosphorylated IkBb, in contrast to the suppressive effects of cytoplasmic IkB, can bind to and activate nuclear p65, promoting NF-kB signaling.
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Protein
A0A0A6YXR5
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
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Protein
A0A0A6YW29
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
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Protein
A0A0A6YW24
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: true
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Publication
10880484 | -
First Author: Aguilera M
Year: 2000
Journal: Genetics
Title: Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins.
Volume: 155
Issue: 3
Pages: 1231-44
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Interaction Experiment
Lin AE (2013)
Description: ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system.
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Protein
A0A0A6YXA7
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
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Protein
A0A0A6YXB0
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
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Protein
Q3TK92
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Publication
32467231 | J:297151
First Author: Wang H
Year: 2020
Journal: J Biol Chem
Title: An aberrantly sustained emergency granulopoiesis response accelerates postchemotherapy relapse in MLL1-rearranged acute myeloid leukemia in mice.
Volume: 295
Issue: 28
Pages: 9663-9675
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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