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Search results 201 to 267 out of 267 for Asah1

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Type Details Score
Publication
33139382 | J:323266
 
First Author: Becker KA
Year: 2021
Journal: Infect Immun
Title: Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections.
Volume: 89
Issue: 2
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Publication
29379059 | J:264488
First Author: Yu FPS
Year: 2018
Journal: Sci Rep
Title: Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency.
Volume: 8
Issue: 1
Pages: 1808
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Publication
31835809 | J:289931
 
First Author: Beckmann N
Year: 2019
Journal: Int J Mol Sci
Title: Acid Sphingomyelinase Deficiency Ameliorates Farber Disease.
Volume: 20
Issue: 24
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Publication
36426850 | J:333409
   
First Author: Hose M
Year: 2022
Journal: Elife
Title: Cell-intrinsic ceramides determine T cell function during melanoma progression.
Volume: 11
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Publication
23770692 | J:199833
First Author: Gulbins E
Year: 2013
Journal: Nat Med
Title: Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs.
Volume: 19
Issue: 7
Pages: 934-8
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Publication
21487040 | J:170975
First Author: Hu X
Year: 2011
Journal: Cancer Res
Title: IRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemia.
Volume: 71
Issue: 8
Pages: 2882-91
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Publication
32817366 | J:310501
 
First Author: Alsamman S
Year: 2020
Journal: Sci Transl Med
Title: Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Volume: 12
Issue: 557
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Publication
38919612 | J:360322
 
First Author: Mandasari P
Year: 2024
Journal: Front Immunol
Title: Acid ceramidase expression reduces IFNγ secretion by mouse CD4(+) T cells and is crucial for maintaining B-cell numbers in mice.
Volume: 15
Pages: 1309846
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Publication
18195024 | J:131574
First Author: Ventura CL
Year: 2008
Journal: Infect Immun
Title: Host airway proteins interact with Staphylococcus aureus during early pneumonia.
Volume: 76
Issue: 3
Pages: 888-98
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Publication
28552668 | J:272682
First Author: Grassmé H
Year: 2017
Journal: Cell Host Microbe
Title: β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections.
Volume: 21
Issue: 6
Pages: 707-718.e8
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Publication
20211931 | J:162830
First Author: Xu YH
Year: 2010
Journal: J Lipid Res
Title: Multi-system disorders of glycosphingolipid and ganglioside metabolism.
Volume: 51
Issue: 7
Pages: 1643-75
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Publication
23096701 | J:196477
First Author: Wang Z
Year: 2013
Journal: J Invest Dermatol
Title: Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.
Volume: 133
Issue: 3
Pages: 668-76
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Publication
29044125 | J:255485
First Author: Li S
Year: 2017
Journal: Sci Rep
Title: Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.
Volume: 7
Issue: 1
Pages: 13427
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q9WV54
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
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DO Term
DOID:0111527 | spinal muscular atrophy with progressive myoclonic epilepsy
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HT Experiment
E-GEOD-74463 | Altered lipid metabolism in the aging kidney identified by three layered omic analysis
Series Id: GSE74463
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Publication
8203897 | -
First Author: Azuma N
Year: 1994
Journal: Arch Biochem Biophys
Title: Stimulation of acid ceramidase activity by saposin D.
Volume: 311
Issue: 2
Pages: 354-7
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Publication
18453694 | -
First Author: Popovic K
Year: 2008
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structures of the human ceramide activator protein saposin D.
Volume: 64
Issue: Pt 5
Pages: 589-94
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Publication
8955159 | -
First Author: Koch J
Year: 1996
Journal: J Biol Chem
Title: Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease.
Volume: 271
Issue: 51
Pages: 33110-5
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Publication
22703880 | -
First Author: Zhou J
Year: 2012
Journal: Am J Hum Genet
Title: Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.
Volume: 91
Issue: 1
Pages: 5-14
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Protein Domain
IPR016699 | Acid_ceramidase-like
Type: Family
Description: This group represents acid ceramidases and some related proteins of currently unknown function. Ceramide is hydrolyzed by both acid and alkaline ceramidase []. Acid ceramidase requires saposin D, a sphingolipid activator protein, for the lysosomal breakdown of ceramide to a fatty acid and sphingosine []. Ceramide is found in plasma membranes and plays a pivotal role in the metabolism of sphingolipids. In addition, ceramide and sphingosine may have important roles as second messengers for cell function and survival []. Mutations of the human acid ceramidase gene, ASAH1, cause Farber lipogranulomatosis (FRBRL), an autosomal recessive lysosomal storage disorder characterised by subcutaneous lipid-loaded nodules, excruciating pain in the joints and extremities, and marked accumulation of ceramide in lysosomes []. Mutations of ASAH1 also cause spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME) [].
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Publication
29401619 | J:256650
   
First Author: Li F
Year: 2018
Journal: FASEB J
Title: Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates.
Pages: fj201700445RR
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Publication
30300671 | J:270213
First Author: Presa N
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice.
Volume: 1865
Issue: 1
Pages: 14-25
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Publication
36614115 | J:332612
 
First Author: Zhou X
Year: 2022
Journal: Int J Mol Sci
Title: iTRAQ-Based Proteomic Analysis of APP Transgenic Mouse Urine Exosomes.
Volume: 24
Issue: 1
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Publication
28847804 | J:253020
First Author: Taguchi YV
Year: 2017
Journal: J Neurosci
Title: Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease.
Volume: 37
Issue: 40
Pages: 9617-9631
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Publication
33352310 | J:316887
 
First Author: Chaurasia B
Year: 2021
Journal: Mol Metab
Title: Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes.
Volume: 45
Pages: 101145
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Protein
Q9D7V9
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: false
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Protein
Q3U8A7
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
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Protein
Q3U646
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
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Protein
Q3TWT5
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
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Protein
Q3V023
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: false
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Protein
G3XA18
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
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Protein
Q78P93
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
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