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Search results 201 to 300 out of 1751 for Atm

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Type Details Score
Publication
First Author: Ito K
Year: 2007
Journal: J Immunol
Title: Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes.
Volume: 178
Issue: 1
Pages: 103-10
Protein
Organism: Mus musculus/domesticus
Length: 867  
Fragment?: false
Allele
Name: ataxia telangiectasia mutated; targeted mutation 1, Philip Leder
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Savic V
Year: 2009
Journal: Mol Cell
Title: Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.
Volume: 34
Issue: 3
Pages: 298-310
Publication
First Author: Panta GR
Year: 2004
Journal: Mol Cell Biol
Title: ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.
Volume: 24
Issue: 5
Pages: 1823-35
Publication
First Author: Lim DS
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: ATM binds to beta-adaptin in cytoplasmic vesicles.
Volume: 95
Issue: 17
Pages: 10146-51
Publication
First Author: Rodrigues PM
Year: 2013
Journal: PLoS One
Title: Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.
Volume: 8
Issue: 7
Pages: e69209
Publication
First Author: Kim J
Year: 2020
Journal: Nucleic Acids Res
Title: Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.
Volume: 48
Issue: 7
Pages: 3678-3691
Publication  
First Author: Liu R
Year: 2017
Journal: DNA Repair (Amst)
Title: ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress.
Volume: 57
Pages: 29-34
Publication
First Author: Hawley RS
Year: 1996
Journal: Genes Dev
Title: Strange bedfellows in even stranger places: the role of ATM in meiotic cells, lymphocytes, tumors, and its functional links to p53.
Volume: 10
Issue: 19
Pages: 2383-8
Publication
First Author: Saito T
Year: 1998
Journal: Mamm Genome
Title: Mouse cdc21 only 0.5 kb upstream from dna-pkcs in a head-to-head organization: an implication of co-evolution of ATM family members and cell cycle regulating genes.
Volume: 9
Issue: 9
Pages: 769-72
Publication
First Author: Kanu N
Year: 2007
Journal: EMBO J
Title: ATMIN defines an NBS1-independent pathway of ATM signalling.
Volume: 26
Issue: 12
Pages: 2933-41
Publication
First Author: Low LH
Year: 2015
Journal: J Biol Chem
Title: Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response.
Volume: 290
Issue: 11
Pages: 7141-50
Publication
First Author: Adams CJ
Year: 2008
Journal: EMBO Rep
Title: ATM and Chk2 kinase target the p53 cofactor Strap.
Volume: 9
Issue: 12
Pages: 1222-9
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Schmitt A
Year: 2017
Journal: Cancer Res
Title: ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma.
Volume: 77
Issue: 11
Pages: 3040-3056
Publication
First Author: Zhao B
Year: 2015
Journal: Cell Stem Cell
Title: Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability.
Volume: 16
Issue: 6
Pages: 684-98
Publication
First Author: Li J
Year: 2013
Journal: Nat Neurosci
Title: EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia.
Volume: 16
Issue: 12
Pages: 1745-53
Publication
First Author: Elson A
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Pleiotropic defects in ataxia-telangiectasia protein-deficient mice.
Volume: 93
Issue: 23
Pages: 13084-9
Publication
First Author: Gueven N
Year: 2006
Journal: Free Radic Biol Med
Title: Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant.
Volume: 41
Issue: 6
Pages: 992-1000
Protein
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
Publication
First Author: Chao C
Year: 2000
Journal: J Immunol
Title: Rescue of defective T cell development and function in Atm-/- mice by a functional TCR alpha beta transgene.
Volume: 164
Issue: 1
Pages: 345-9
Publication
First Author: Hamer G
Year: 2004
Journal: Biol Reprod
Title: Ataxia telangiectasia mutated expression and activation in the testis.
Volume: 70
Issue: 4
Pages: 1206-12
Publication
First Author: Eilam R
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice.
Volume: 95
Issue: 21
Pages: 12653-6
Publication
First Author: Lu S
Year: 2005
Journal: Hum Mol Genet
Title: Impaired hepatocyte survival and liver regeneration in Atm-deficient mice.
Volume: 14
Issue: 20
Pages: 3019-25
Publication
First Author: Desgranges ZP
Year: 2005
Journal: Mol Cell Biol
Title: Inhibition of TFII-I-dependent cell cycle regulation by p53.
Volume: 25
Issue: 24
Pages: 10940-52
Publication
First Author: Lu S
Year: 2006
Journal: Carcinogenesis
Title: Atm-haploinsufficiency enhances susceptibility to carcinogen-induced mammary tumors.
Volume: 27
Issue: 4
Pages: 848-55
Publication
First Author: Bagley J
Year: 2007
Journal: J Immunol
Title: Regulation of oxidative stress responses by ataxia-telangiectasia mutated is required for T cell proliferation.
Volume: 178
Issue: 8
Pages: 4757-63
Publication
First Author: Eilam R
Year: 2003
Journal: Neuroscience
Title: Late degeneration of nigro-striatal neurons in ATM-/- mice.
Volume: 121
Issue: 1
Pages: 83-98
Publication
First Author: Song X
Year: 2021
Journal: J Neurosci
Title: DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response.
Volume: 41
Issue: 45
Pages: 9286-9307
Publication
First Author: Kanner S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Astrocytes restore connectivity and synchronization in dysfunctional cerebellar networks.
Volume: 115
Issue: 31
Pages: 8025-8030
Publication
First Author: Laposa RR
Year: 2004
Journal: FASEB J
Title: Atm-null mice exhibit enhanced radiation-induced birth defects and a hybrid form of embryonic programmed cell death indicating a teratological suppressor function for ATM.
Volume: 18
Issue: 7
Pages: 896-8
Publication
First Author: Barlow C
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.
Volume: 96
Issue: 17
Pages: 9915-9
Publication
First Author: Miles PD
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Impaired insulin secretion in a mouse model of ataxia telangiectasia.
Volume: 293
Issue: 1
Pages: E70-4
Publication
First Author: Macleod MR
Year: 2003
Journal: Neuroreport
Title: Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein.
Volume: 14
Issue: 2
Pages: 215-7
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Biswas S
Year: 2013
Journal: Cell Death Differ
Title: The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm-/- mice.
Volume: 20
Issue: 7
Pages: 869-77
Publication
First Author: Kuang X
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm-/- mice.
Volume: 383
Issue: 3
Pages: 368-72
Publication
First Author: Hishiya A
Year: 2005
Journal: Bone
Title: Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation.
Volume: 37
Issue: 4
Pages: 497-503
Publication
First Author: Hibma JC
Year: 2007
Journal: Anat Rec (Hoboken)
Title: A novel phenotypic marker for ATM-deficient 129S6/SvEvTac-ATMtm1Awb/J mice.
Volume: 290
Issue: 3
Pages: 243-50
Publication
First Author: Kulinski JM
Year: 2012
Journal: J Virol
Title: Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection.
Volume: 86
Issue: 23
Pages: 12826-37
Publication
First Author: Winrow CJ
Year: 2005
Journal: Hum Mol Genet
Title: Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas.
Volume: 14
Issue: 18
Pages: 2671-84
Publication
First Author: Raz-Prag D
Year: 2011
Journal: Am J Pathol
Title: A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia.
Volume: 179
Issue: 3
Pages: 1533-41
Publication
First Author: Yan M
Year: 2008
Journal: Neoplasia
Title: Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress.
Volume: 10
Issue: 2
Pages: 160-7
Publication
First Author: Zhan H
Year: 2010
Journal: J Biol Chem
Title: Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.
Volume: 285
Issue: 38
Pages: 29662-70
Publication
First Author: Bhatwadekar AD
Year: 2016
Journal: Stem Cells
Title: Ataxia Telangiectasia Mutated Dysregulation Results in Diabetic Retinopathy.
Volume: 34
Issue: 2
Pages: 405-17
Publication
First Author: Mount HT
Year: 2004
Journal: J Neurochem
Title: Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.
Volume: 88
Issue: 6
Pages: 1449-54
Publication
First Author: Hande MP
Year: 2001
Journal: Hum Mol Genet
Title: Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia.
Volume: 10
Issue: 5
Pages: 519-28
Publication
First Author: Daniel LL
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Ataxia telangiectasia-mutated kinase deficiency exacerbates left ventricular dysfunction and remodeling late after myocardial infarction.
Volume: 311
Issue: 2
Pages: H445-52
Publication
First Author: Eaton JS
Year: 2007
Journal: J Clin Invest
Title: Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis.
Volume: 117
Issue: 9
Pages: 2723-34
Publication
First Author: Stern N
Year: 2002
Journal: J Biol Chem
Title: Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice.
Volume: 277
Issue: 1
Pages: 602-8
Publication
First Author: Huang CY
Year: 2007
Journal: J Exp Med
Title: Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes.
Volume: 204
Issue: 6
Pages: 1371-81
Publication
First Author: Westbrook AM
Year: 2010
Journal: Cancer Res
Title: Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.
Volume: 70
Issue: 5
Pages: 1875-84
Publication
First Author: Rasheed N
Year: 2006
Journal: Hum Mol Genet
Title: Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis.
Volume: 15
Issue: 12
Pages: 1938-48
Publication
First Author: Liyanage M
Year: 2000
Journal: Blood
Title: Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice.
Volume: 96
Issue: 5
Pages: 1940-6
Publication
First Author: Patel AY
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Ataxia telangiectasia mutated influences cytochrome c oxidase activity.
Volume: 405
Issue: 4
Pages: 599-603
Publication
First Author: Bloom SI
Year: 2023
Journal: Aging (Albany NY)
Title: Reduction of double-strand DNA break repair exacerbates vascular aging.
Volume: 15
Issue: 19
Pages: 9913-9947
Publication
First Author: Schubert R
Year: 2004
Journal: Hum Mol Genet
Title: Cancer chemoprevention by the antioxidant tempol in Atm-deficient mice.
Volume: 13
Issue: 16
Pages: 1793-802
Publication
First Author: Clark KL
Year: 2020
Journal: Biol Reprod
Title: Ataxia-telangiectasia mutated coordinates the ovarian DNA repair and atresia-initiating response to phosphoramide mustard.
Volume: 102
Issue: 1
Pages: 248-260
Publication
First Author: Allen DM
Year: 2001
Journal: Genes Dev
Title: Ataxia telangiectasia mutated is essential during adult neurogenesis.
Volume: 15
Issue: 5
Pages: 554-66
Publication
First Author: Lumsden JM
Year: 2004
Journal: J Exp Med
Title: Immunoglobulin class switch recombination is impaired in Atm-deficient mice.
Volume: 200
Issue: 9
Pages: 1111-21
Publication
First Author: Park BJ
Year: 2005
Journal: Cell
Title: The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR.
Volume: 120
Issue: 2
Pages: 209-21
Publication
First Author: Weyemi U
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease.
Volume: 112
Issue: 7
Pages: 2121-6
Publication
First Author: Campbell A
Year: 2016
Journal: Glia
Title: Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.
Volume: 64
Issue: 2
Pages: 227-39
Publication
First Author: Moens PB
Year: 1999
Journal: Chromosoma
Title: The association of ATR protein with mouse meiotic chromosome cores.
Volume: 108
Issue: 2
Pages: 95-102
Publication
First Author: Thrasher PR
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Ataxia telangiectasia mutated kinase deficiency impairs the autophagic response early during myocardial infarction.
Volume: 315
Issue: 1
Pages: H48-H57
Protein
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
Publication
First Author: Horn D
Year: 2016
Journal: Am J Med Genet A
Title: BRAT1 mutations are associated with infantile epileptic encephalopathy, mitochondrial dysfunction, and survival into childhood.
Volume: 170
Issue: 9
Pages: 2274-81
Publication
First Author: Saitsu H
Year: 2014
Journal: J Hum Genet
Title: Compound heterozygous BRAT1 mutations cause familial Ohtahara syndrome with hypertonia and microcephaly.
Volume: 59
Issue: 12
Pages: 687-90
Publication  
First Author: So EY
Year: 2014
Journal: BMC Cancer
Title: BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction.
Volume: 14
Pages: 548
Protein Domain
Type: Family
Description: BRAT1 binds to ATM and BRCA1 and is involved in DNA damage-induced ATM activation []. It is also involved in cell proliferation and mitochondrial functions []. Mutations of the BRAT1 gene have been linked to epileptic encephalopathy [, ].
Publication
First Author: Kuang X
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species.
Volume: 418
Issue: 2
Pages: 267-72
Publication
First Author: Wang YA
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice.
Volume: 94
Issue: 26
Pages: 14590-5
Publication
First Author: Feldser D
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres.
Volume: 103
Issue: 7
Pages: 2249-51
Publication
First Author: Qi L
Year: 2003
Journal: Cancer Res
Title: Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.
Volume: 63
Issue: 23
Pages: 8188-96
Publication
First Author: Kim J
Year: 2011
Journal: PLoS One
Title: p38 MAPK-Mediated Bmi-1 down-regulation and defective proliferation in ATM-deficient neural stem cells can be restored by Akt activation.
Volume: 6
Issue: 1
Pages: e16615
Publication
First Author: D'Souza AD
Year: 2011
Journal: Am J Pathol
Title: Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
Volume: 178
Issue: 6
Pages: 2740-51
Publication
First Author: Peter Y
Year: 2001
Journal: EMBO J
Title: Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice.
Volume: 20
Issue: 7
Pages: 1538-46
Publication
First Author: Fang EF
Year: 2016
Journal: Cell Metab
Title: NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair.
Volume: 24
Issue: 4
Pages: 566-581
Publication
First Author: Yang B
Year: 2021
Journal: Aging Cell
Title: NAD+ supplementation prevents STING-induced senescence in ataxia telangiectasia by improving mitophagy.
Volume: 20
Issue: 4
Pages: e13329
Publication
First Author: Kim J
Year: 2009
Journal: J Biol Chem
Title: Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes.
Volume: 284
Issue: 21
Pages: 14396-404
Publication
First Author: Chen J
Year: 2016
Journal: Mol Neurodegener
Title: The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.
Volume: 11
Issue: 1
Pages: 60
Publication
First Author: Heierhorst J
Year: 2011
Journal: Cell Cycle
Title: A breathtaking phenotype: unexpected roles of the DNA base damage response protein ASCIZ as a key regulator of early lung development.
Volume: 10
Issue: 8
Pages: 1222-4
Publication  
First Author: Chau JF
Year: 2012
Journal: Nat Commun
Title: A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response.
Volume: 3
Pages: 836
Publication
First Author: Paulson QX
Year: 2008
Journal: Oncogene
Title: Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.
Volume: 27
Issue: 36
Pages: 4954-61
Publication
First Author: Puccini J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.
Volume: 110
Issue: 49
Pages: 19920-5
Publication
First Author: Balmus G
Year: 2012
Journal: Hum Mol Genet
Title: Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.
Volume: 21
Issue: 15
Pages: 3408-20
Publication
First Author: Zenvirth D
Year: 2003
Journal: Chromosoma
Title: Mammalian meiosis involves DNA double-strand breaks with 3' overhangs.
Volume: 111
Issue: 6
Pages: 369-76
Publication
First Author: Lukaszewicz A
Year: 2021
Journal: Cell
Title: De novo deletions and duplications at recombination hotspots in mouse germlines.
Volume: 184
Issue: 24
Pages: 5970-5984.e18
Publication
First Author: Tomic J
Year: 2011
Journal: Blood
Title: Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia.
Volume: 117
Issue: 9
Pages: 2668-80
Publication
First Author: Frohns A
Year: 2014
Journal: Curr Biol
Title: Inefficient double-strand break repair in murine rod photoreceptors with inverted heterochromatin organization.
Volume: 24
Issue: 10
Pages: 1080-90
Publication
First Author: Bagley J
Year: 2004
Journal: Blood
Title: Bone marrow transplantation restores immune system function and prevents lymphoma in Atm-deficient mice.
Volume: 104
Issue: 2
Pages: 572-8
Publication
First Author: Chen Y
Year: 2014
Journal: Protein Cell
Title: Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice.
Volume: 5
Issue: 1
Pages: 80-9
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, African clawed