Type |
Details |
Score |
Publication |
First Author: |
Ito K |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. |
Volume: |
178 |
Issue: |
1 |
Pages: |
103-10 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
867
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
ataxia telangiectasia mutated; targeted mutation 1, Philip Leder |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Savic V |
Year: |
2009 |
Journal: |
Mol Cell |
Title: |
Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. |
Volume: |
34 |
Issue: |
3 |
Pages: |
298-310 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panta GR |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage. |
Volume: |
24 |
Issue: |
5 |
Pages: |
1823-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lim DS |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ATM binds to beta-adaptin in cytoplasmic vesicles. |
Volume: |
95 |
Issue: |
17 |
Pages: |
10146-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodrigues PM |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye. |
Volume: |
8 |
Issue: |
7 |
Pages: |
e69209 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim J |
Year: |
2020 |
Journal: |
Nucleic Acids Res |
Title: |
Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation. |
Volume: |
48 |
Issue: |
7 |
Pages: |
3678-3691 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu R |
Year: |
2017 |
Journal: |
DNA Repair (Amst) |
Title: |
ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress. |
Volume: |
57 |
|
Pages: |
29-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hawley RS |
Year: |
1996 |
Journal: |
Genes Dev |
Title: |
Strange bedfellows in even stranger places: the role of ATM in meiotic cells, lymphocytes, tumors, and its functional links to p53. |
Volume: |
10 |
Issue: |
19 |
Pages: |
2383-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saito T |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Mouse cdc21 only 0.5 kb upstream from dna-pkcs in a head-to-head organization: an implication of co-evolution of ATM family members and cell cycle regulating genes. |
Volume: |
9 |
Issue: |
9 |
Pages: |
769-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanu N |
Year: |
2007 |
Journal: |
EMBO J |
Title: |
ATMIN defines an NBS1-independent pathway of ATM signalling. |
Volume: |
26 |
Issue: |
12 |
Pages: |
2933-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Low LH |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response. |
Volume: |
290 |
Issue: |
11 |
Pages: |
7141-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams CJ |
Year: |
2008 |
Journal: |
EMBO Rep |
Title: |
ATM and Chk2 kinase target the p53 cofactor Strap. |
Volume: |
9 |
Issue: |
12 |
Pages: |
1222-9 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmitt A |
Year: |
2017 |
Journal: |
Cancer Res |
Title: |
ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma. |
Volume: |
77 |
Issue: |
11 |
Pages: |
3040-3056 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao B |
Year: |
2015 |
Journal: |
Cell Stem Cell |
Title: |
Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability. |
Volume: |
16 |
Issue: |
6 |
Pages: |
684-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2013 |
Journal: |
Nat Neurosci |
Title: |
EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia. |
Volume: |
16 |
Issue: |
12 |
Pages: |
1745-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elson A |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. |
Volume: |
93 |
Issue: |
23 |
Pages: |
13084-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gueven N |
Year: |
2006 |
Journal: |
Free Radic Biol Med |
Title: |
Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant. |
Volume: |
41 |
Issue: |
6 |
Pages: |
992-1000 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
597
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chao C |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Rescue of defective T cell development and function in Atm-/- mice by a functional TCR alpha beta transgene. |
Volume: |
164 |
Issue: |
1 |
Pages: |
345-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamer G |
Year: |
2004 |
Journal: |
Biol Reprod |
Title: |
Ataxia telangiectasia mutated expression and activation in the testis. |
Volume: |
70 |
Issue: |
4 |
Pages: |
1206-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eilam R |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice. |
Volume: |
95 |
Issue: |
21 |
Pages: |
12653-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu S |
Year: |
2005 |
Journal: |
Hum Mol Genet |
Title: |
Impaired hepatocyte survival and liver regeneration in Atm-deficient mice. |
Volume: |
14 |
Issue: |
20 |
Pages: |
3019-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Desgranges ZP |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Inhibition of TFII-I-dependent cell cycle regulation by p53. |
Volume: |
25 |
Issue: |
24 |
Pages: |
10940-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu S |
Year: |
2006 |
Journal: |
Carcinogenesis |
Title: |
Atm-haploinsufficiency enhances susceptibility to carcinogen-induced mammary tumors. |
Volume: |
27 |
Issue: |
4 |
Pages: |
848-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bagley J |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Regulation of oxidative stress responses by ataxia-telangiectasia mutated is required for T cell proliferation. |
Volume: |
178 |
Issue: |
8 |
Pages: |
4757-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eilam R |
Year: |
2003 |
Journal: |
Neuroscience |
Title: |
Late degeneration of nigro-striatal neurons in ATM-/- mice. |
Volume: |
121 |
Issue: |
1 |
Pages: |
83-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song X |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response. |
Volume: |
41 |
Issue: |
45 |
Pages: |
9286-9307 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanner S |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Astrocytes restore connectivity and synchronization in dysfunctional cerebellar networks. |
Volume: |
115 |
Issue: |
31 |
Pages: |
8025-8030 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laposa RR |
Year: |
2004 |
Journal: |
FASEB J |
Title: |
Atm-null mice exhibit enhanced radiation-induced birth defects and a hybrid form of embryonic programmed cell death indicating a teratological suppressor function for ATM. |
Volume: |
18 |
Issue: |
7 |
Pages: |
896-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barlow C |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. |
Volume: |
96 |
Issue: |
17 |
Pages: |
9915-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miles PD |
Year: |
2007 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Impaired insulin secretion in a mouse model of ataxia telangiectasia. |
Volume: |
293 |
Issue: |
1 |
Pages: |
E70-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Macleod MR |
Year: |
2003 |
Journal: |
Neuroreport |
Title: |
Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein. |
Volume: |
14 |
Issue: |
2 |
Pages: |
215-7 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas S |
Year: |
2013 |
Journal: |
Cell Death Differ |
Title: |
The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm-/- mice. |
Volume: |
20 |
Issue: |
7 |
Pages: |
869-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuang X |
Year: |
2009 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm-/- mice. |
Volume: |
383 |
Issue: |
3 |
Pages: |
368-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hishiya A |
Year: |
2005 |
Journal: |
Bone |
Title: |
Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation. |
Volume: |
37 |
Issue: |
4 |
Pages: |
497-503 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hibma JC |
Year: |
2007 |
Journal: |
Anat Rec (Hoboken) |
Title: |
A novel phenotypic marker for ATM-deficient 129S6/SvEvTac-ATMtm1Awb/J mice. |
Volume: |
290 |
Issue: |
3 |
Pages: |
243-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kulinski JM |
Year: |
2012 |
Journal: |
J Virol |
Title: |
Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection. |
Volume: |
86 |
Issue: |
23 |
Pages: |
12826-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winrow CJ |
Year: |
2005 |
Journal: |
Hum Mol Genet |
Title: |
Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas. |
Volume: |
14 |
Issue: |
18 |
Pages: |
2671-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raz-Prag D |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia. |
Volume: |
179 |
Issue: |
3 |
Pages: |
1533-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan M |
Year: |
2008 |
Journal: |
Neoplasia |
Title: |
Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress. |
Volume: |
10 |
Issue: |
2 |
Pages: |
160-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhan H |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence. |
Volume: |
285 |
Issue: |
38 |
Pages: |
29662-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhatwadekar AD |
Year: |
2016 |
Journal: |
Stem Cells |
Title: |
Ataxia Telangiectasia Mutated Dysregulation Results in Diabetic Retinopathy. |
Volume: |
34 |
Issue: |
2 |
Pages: |
405-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mount HT |
Year: |
2004 |
Journal: |
J Neurochem |
Title: |
Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia. |
Volume: |
88 |
Issue: |
6 |
Pages: |
1449-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hande MP |
Year: |
2001 |
Journal: |
Hum Mol Genet |
Title: |
Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. |
Volume: |
10 |
Issue: |
5 |
Pages: |
519-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daniel LL |
Year: |
2016 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Ataxia telangiectasia-mutated kinase deficiency exacerbates left ventricular dysfunction and remodeling late after myocardial infarction. |
Volume: |
311 |
Issue: |
2 |
Pages: |
H445-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eaton JS |
Year: |
2007 |
Journal: |
J Clin Invest |
Title: |
Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis. |
Volume: |
117 |
Issue: |
9 |
Pages: |
2723-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stern N |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice. |
Volume: |
277 |
Issue: |
1 |
Pages: |
602-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang CY |
Year: |
2007 |
Journal: |
J Exp Med |
Title: |
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. |
Volume: |
204 |
Issue: |
6 |
Pages: |
1371-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Westbrook AM |
Year: |
2010 |
Journal: |
Cancer Res |
Title: |
Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. |
Volume: |
70 |
Issue: |
5 |
Pages: |
1875-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rasheed N |
Year: |
2006 |
Journal: |
Hum Mol Genet |
Title: |
Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis. |
Volume: |
15 |
Issue: |
12 |
Pages: |
1938-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liyanage M |
Year: |
2000 |
Journal: |
Blood |
Title: |
Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice. |
Volume: |
96 |
Issue: |
5 |
Pages: |
1940-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel AY |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Ataxia telangiectasia mutated influences cytochrome c oxidase activity. |
Volume: |
405 |
Issue: |
4 |
Pages: |
599-603 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bloom SI |
Year: |
2023 |
Journal: |
Aging (Albany NY) |
Title: |
Reduction of double-strand DNA break repair exacerbates vascular aging. |
Volume: |
15 |
Issue: |
19 |
Pages: |
9913-9947 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schubert R |
Year: |
2004 |
Journal: |
Hum Mol Genet |
Title: |
Cancer chemoprevention by the antioxidant tempol in Atm-deficient mice. |
Volume: |
13 |
Issue: |
16 |
Pages: |
1793-802 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clark KL |
Year: |
2020 |
Journal: |
Biol Reprod |
Title: |
Ataxia-telangiectasia mutated coordinates the ovarian DNA repair and atresia-initiating response to phosphoramide mustard. |
Volume: |
102 |
Issue: |
1 |
Pages: |
248-260 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allen DM |
Year: |
2001 |
Journal: |
Genes Dev |
Title: |
Ataxia telangiectasia mutated is essential during adult neurogenesis. |
Volume: |
15 |
Issue: |
5 |
Pages: |
554-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lumsden JM |
Year: |
2004 |
Journal: |
J Exp Med |
Title: |
Immunoglobulin class switch recombination is impaired in Atm-deficient mice. |
Volume: |
200 |
Issue: |
9 |
Pages: |
1111-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park BJ |
Year: |
2005 |
Journal: |
Cell |
Title: |
The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR. |
Volume: |
120 |
Issue: |
2 |
Pages: |
209-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weyemi U |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease. |
Volume: |
112 |
Issue: |
7 |
Pages: |
2121-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campbell A |
Year: |
2016 |
Journal: |
Glia |
Title: |
Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia. |
Volume: |
64 |
Issue: |
2 |
Pages: |
227-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moens PB |
Year: |
1999 |
Journal: |
Chromosoma |
Title: |
The association of ATR protein with mouse meiotic chromosome cores. |
Volume: |
108 |
Issue: |
2 |
Pages: |
95-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thrasher PR |
Year: |
2018 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Ataxia telangiectasia mutated kinase deficiency impairs the autophagic response early during myocardial infarction. |
Volume: |
315 |
Issue: |
1 |
Pages: |
H48-H57 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
228
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Horn D |
Year: |
2016 |
Journal: |
Am J Med Genet A |
Title: |
BRAT1 mutations are associated with infantile epileptic encephalopathy, mitochondrial dysfunction, and survival into childhood. |
Volume: |
170 |
Issue: |
9 |
Pages: |
2274-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saitsu H |
Year: |
2014 |
Journal: |
J Hum Genet |
Title: |
Compound heterozygous BRAT1 mutations cause familial Ohtahara syndrome with hypertonia and microcephaly. |
Volume: |
59 |
Issue: |
12 |
Pages: |
687-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
So EY |
Year: |
2014 |
Journal: |
BMC Cancer |
Title: |
BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction. |
Volume: |
14 |
|
Pages: |
548 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
BRAT1 binds to ATM and BRCA1 and is involved in DNA damage-induced ATM activation []. It is also involved in cell proliferation and mitochondrial functions []. Mutations of the BRAT1 gene have been linked to epileptic encephalopathy [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuang X |
Year: |
2012 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species. |
Volume: |
418 |
Issue: |
2 |
Pages: |
267-72 |
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Publication |
First Author: |
Wang YA |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice. |
Volume: |
94 |
Issue: |
26 |
Pages: |
14590-5 |
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Publication |
First Author: |
Feldser D |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres. |
Volume: |
103 |
Issue: |
7 |
Pages: |
2249-51 |
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Publication |
First Author: |
Qi L |
Year: |
2003 |
Journal: |
Cancer Res |
Title: |
Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis. |
Volume: |
63 |
Issue: |
23 |
Pages: |
8188-96 |
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Publication |
First Author: |
Kim J |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
p38 MAPK-Mediated Bmi-1 down-regulation and defective proliferation in ATM-deficient neural stem cells can be restored by Akt activation. |
Volume: |
6 |
Issue: |
1 |
Pages: |
e16615 |
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Publication |
First Author: |
D'Souza AD |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling. |
Volume: |
178 |
Issue: |
6 |
Pages: |
2740-51 |
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Publication |
First Author: |
Peter Y |
Year: |
2001 |
Journal: |
EMBO J |
Title: |
Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice. |
Volume: |
20 |
Issue: |
7 |
Pages: |
1538-46 |
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Publication |
First Author: |
Fang EF |
Year: |
2016 |
Journal: |
Cell Metab |
Title: |
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. |
Volume: |
24 |
Issue: |
4 |
Pages: |
566-581 |
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Publication |
First Author: |
Yang B |
Year: |
2021 |
Journal: |
Aging Cell |
Title: |
NAD+ supplementation prevents STING-induced senescence in ataxia telangiectasia by improving mitophagy. |
Volume: |
20 |
Issue: |
4 |
Pages: |
e13329 |
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Publication |
First Author: |
Kim J |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes. |
Volume: |
284 |
Issue: |
21 |
Pages: |
14396-404 |
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Publication |
First Author: |
Chen J |
Year: |
2016 |
Journal: |
Mol Neurodegener |
Title: |
The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment. |
Volume: |
11 |
Issue: |
1 |
Pages: |
60 |
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Publication |
First Author: |
Heierhorst J |
Year: |
2011 |
Journal: |
Cell Cycle |
Title: |
A breathtaking phenotype: unexpected roles of the DNA base damage response protein ASCIZ as a key regulator of early lung development. |
Volume: |
10 |
Issue: |
8 |
Pages: |
1222-4 |
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Publication |
First Author: |
Chau JF |
Year: |
2012 |
Journal: |
Nat Commun |
Title: |
A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response. |
Volume: |
3 |
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Pages: |
836 |
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Publication |
First Author: |
Paulson QX |
Year: |
2008 |
Journal: |
Oncogene |
Title: |
Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis. |
Volume: |
27 |
Issue: |
36 |
Pages: |
4954-61 |
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Publication |
First Author: |
Puccini J |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice. |
Volume: |
110 |
Issue: |
49 |
Pages: |
19920-5 |
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Publication |
First Author: |
Balmus G |
Year: |
2012 |
Journal: |
Hum Mol Genet |
Title: |
Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1. |
Volume: |
21 |
Issue: |
15 |
Pages: |
3408-20 |
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Publication |
First Author: |
Zenvirth D |
Year: |
2003 |
Journal: |
Chromosoma |
Title: |
Mammalian meiosis involves DNA double-strand breaks with 3' overhangs. |
Volume: |
111 |
Issue: |
6 |
Pages: |
369-76 |
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Publication |
First Author: |
Lukaszewicz A |
Year: |
2021 |
Journal: |
Cell |
Title: |
De novo deletions and duplications at recombination hotspots in mouse germlines. |
Volume: |
184 |
Issue: |
24 |
Pages: |
5970-5984.e18 |
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Publication |
First Author: |
Tomic J |
Year: |
2011 |
Journal: |
Blood |
Title: |
Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia. |
Volume: |
117 |
Issue: |
9 |
Pages: |
2668-80 |
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Publication |
First Author: |
Frohns A |
Year: |
2014 |
Journal: |
Curr Biol |
Title: |
Inefficient double-strand break repair in murine rod photoreceptors with inverted heterochromatin organization. |
Volume: |
24 |
Issue: |
10 |
Pages: |
1080-90 |
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Publication |
First Author: |
Bagley J |
Year: |
2004 |
Journal: |
Blood |
Title: |
Bone marrow transplantation restores immune system function and prevents lymphoma in Atm-deficient mice. |
Volume: |
104 |
Issue: |
2 |
Pages: |
572-8 |
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Publication |
First Author: |
Chen Y |
Year: |
2014 |
Journal: |
Protein Cell |
Title: |
Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice. |
Volume: |
5 |
Issue: |
1 |
Pages: |
80-9 |
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Gene |
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Gene |
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Gene |
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Gene |
Type: |
gene |
Organism: |
zebrafish |
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Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
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Gene |
Type: |
gene |
Organism: |
frog, western clawed |
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Gene |
Type: |
gene |
Organism: |
frog, African clawed |
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