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Search results 201 to 294 out of 294 for Atxn3

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Type Details Score
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
28624196 | J:328145
 
First Author: Moore LR
Year: 2017
Journal: Mol Ther Nucleic Acids
Title: Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models.
Volume: 7
Pages: 200-210
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Strain
MGI:5499151 | B6.129S2-Atxn3<Gt(A041D06)Wrst>/Ieg
Attribute String: congenic, gene trap, mutant strain
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Publication
25590633 | J:248592
First Author: Gao R
Year: 2015
Journal: PLoS Genet
Title: Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3.
Volume: 11
Issue: 1
Pages: e1004834
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Publication
33157014 | J:300167
First Author: Yao Y
Year: 2020
Journal: Mol Cell
Title: Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity.
Volume: 80
Issue: 3
Pages: 437-451.e6
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Interaction Experiment
Wang S (2023)
Description: ATXN3 deubiquitinates YAP1 to promote tumor growth.
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Publication
37818078 | -
First Author: Wang S
Year: 2023
Journal: Am J Cancer Res
Title: ATXN3 deubiquitinates YAP1 to promote tumor growth.
Volume: 13
Issue: 9
Pages: 4222-4234
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Protein
F7CXJ2
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
E9PZT4
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: false
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Publication
27133716 | -
First Author: Ito N
Year: 2016
Journal: Biochem Biophys Res Commun
Title: A novel nuclear DnaJ protein, DNAJC8, can suppress the formation of spinocerebellar ataxia 3 polyglutamine aggregation in a J-domain independent manner.
Volume: 474
Issue: 4
Pages: 626-633
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Protein Domain
IPR042858 | DNAJC8
Type: Family
Description: DnaJ homolog subfamily C member 8 (DNAJC8) suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells [].
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Gene
8678 | BECN1
Type: gene
Organism: human
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Allele
Tg(ATXN3*)84.2Cce | MGI:3838155
Name: transgene insertion 84.2, Cemal K Cemal
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(ATXN3*)67.2Cce | MGI:3838156
Name: transgene insertion 67.2, Cemal K Cemal
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(tetO-ATXN3)2904Olri | MGI:4410556
Name: transgene insertion 2904, Olaf Riess
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(Htt-ATXN3*148Q)3746Thsc | MGI:4429385
Name: transgene insertion 3746, Thorsten Schmidt
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CMV-ATXN3*94Q)94Pama | MGI:4822570
Name: transgene insertion 94, Patricia Maciel
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-ATXN3*79Q)#Hlw | MGI:4940057
Name: transgene insertion, Hung-Li Wang
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-ATXN3*70Q)70.61Olri | MGI:5516451
Name: transgene insertion 70.61, Olaf Riess
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-ATXN3*148Q)148.19Olri | MGI:5516452
Name: transgene insertion 148.19, Olaf Riess
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-ATXN3*148Q)NLS.28Olri | MGI:5516462
Name: transgene insertion NLS.28, Olaf Riess
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Pcp2-ATXN3*69Q)bHirai | MGI:5523235
Name: transgene insertion b, Hirokazu Hirai
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CMV-ATXN3*135Q)CPama | MGI:5646300
Name: transgene insertion C, Patricia Maciel
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Atxn3<tm2.1(ATXN3*)Mfig> | MGI:5708157
Name: ataxin 3; targeted mutation 2.1, Maciej Figiel
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Atxn3<Gt(VICTR48)1Lex> | MGI:6116707
Name: ataxin 3; gene trap mutation 1, Lexicon Genetics
Allele Type: Gene trapped
Attribute String: Null/knockout
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Allele
Atxn3<tm1(ATXN3)Cya> | MGI:7657214
Name: ataxin 3; targeted mutation 1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Transgene
MGI:3838160 | Tg(ATXN3*)84.2Cce
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3838159 | Tg(ATXN3*)67.2Cce
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4429400 | Tg(Htt-ATXN3*148Q)3746Thsc
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4822569 | Tg(CMV-ATXN3*94Q)94Pama
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4940058 | Tg(Prnp-ATXN3*79Q)#Hlw
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5516449 | Tg(Prnp-ATXN3*70Q)70.61Olri
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5516450 | Tg(Prnp-ATXN3*148Q)148.19Olri
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5516461 | Tg(Prnp-ATXN3*148Q)NLS.28Olri
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5523234 | Tg(Pcp2-ATXN3*69Q)bHirai
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5646298 | Tg(CMV-ATXN3*135Q)CPama
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(ATXN3*)67.2Cce/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(ATXN3*)67.2Cce/? Tg(ATXN3*)84.2Cce/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(ATXN3*)84.2Cce/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(ATXN3*)84.2Cce/Tg(ATXN3*)84.2Cce
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/Tg(Prnp-tTA)F959Sbp Tg(tetO-ATXN3)2904Olri/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/? Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/Tg(Prnp-tTA)F959Sbp Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Htt-ATXN3*148Q)3746Thsc/?
Background: involves: C57BL/6N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CMV-ATXN3*94Q)94Pama/?
Background: B6.FVB-Tg(CMV-ATXN3*94Q)94Pama
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CMV-ATXN3*94Q)94Pama/Tg(CMV-ATXN3*94Q)94Pama
Background: B6.FVB-Tg(CMV-ATXN3*94Q)94Pama
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ATXN3*79Q)#Hlw/?
Background: FVB/N-Tg(Prnp-ATXN3*79Q)#Hlw
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Atxn3/Atxn3<+>
Background: involves: 129 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ATXN3*70Q)70.61Olri/?
Background: involves: C57BL/6N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ATXN3*148Q)148.19Olri/?
Background: involves: C57BL/6N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ATXN3*148Q)NLS.28Olri/?
Background: involves: C57BL/6N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pcp2-ATXN3*69Q)bHirai/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CMV-ATXN3*135Q)CPama/?
Background: C57BL/6-Tg(CMV-ATXN3*135Q)CPama
Zygosity: ot
Has Mutant Allele: true
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DO Term
DOID:1440 | Machado-Joseph disease
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Strain
MGI:7657598 | C57BL/6N-Atxn3<tm1(ATXN3)Cya>/Cya
Attribute String: coisogenic, targeted mutation, mutant strain
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Allele
Tg(Pmch-ATXN3*)3Rck | MGI:3785576
Name: transgene insertion 3, Jeffrey M Friedman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
16407534 | J:104264
First Author: Alon T
Year: 2006
Journal: J Neurosci
Title: Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons.
Volume: 26
Issue: 2
Pages: 389-97
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Strain
MGI:3785802 | FVB/NJ-Tg(Pmch-ATXN3*)3Rck/J
Attribute String: transgenic, coisogenic
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Genotype
Genotype
Symbol: Lep/Lep Tg(Pmch-ATXN3*)3Rck/?
Background: involves: C57BL/6J * FVB/NJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pmch-ATXN3*)3Rck/?
Background: involves: FVB/NJ
Zygosity: ot
Has Mutant Allele: true
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Publication
27165717 | J:239933
 
First Author: Cunha-Santos J
Year: 2016
Journal: Nat Commun
Title: Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
Volume: 7
Pages: 11445
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Publication
19542537 | J:151499
First Author: Mueller T
Year: 2009
Journal: Hum Mol Genet
Title: CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.
Volume: 18
Issue: 17
Pages: 3334-43
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Publication
27929117 | J:341031
 
First Author: Pavel M
Year: 2016
Journal: Nat Commun
Title: CCT complex restricts neuropathogenic protein aggregation via autophagy.
Volume: 7
Pages: 13821
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Protein
D3Z4I5
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
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Publication
29476013 | J:259776
First Author: Sowa AS
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Volume: 115
Issue: 11
Pages: E2624-E2633
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Publication
24418349 | J:259964
 
First Author: Mateu-Huertas E
Year: 2014
Journal: Neurobiol Dis
Title: Blood expression profiles of fragile X premutation carriers identify candidate genes involved in neurodegenerative and infertility phenotypes.
Volume: 65
Pages: 43-54
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Publication
23765441 | J:220882
First Author: Costa Mdo C
Year: 2013
Journal: Mol Ther
Title: Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Volume: 21
Issue: 10
Pages: 1898-908
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Publication
29908063 | J:328147
First Author: McLoughlin HS
Year: 2018
Journal: Ann Neurol
Title: Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice.
Volume: 84
Issue: 1
Pages: 64-77
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Publication
34199295 | J:313740
 
First Author: Lee JH
Year: 2021
Journal: Int J Mol Sci
Title: n-Butylidenephthalide Modulates Autophagy to Ameliorate Neuropathological Progress of Spinocerebellar Ataxia Type 3 through mTOR Pathway.
Volume: 22
Issue: 12
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Publication
32205441 | J:290131
First Author: Chakraborty A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
Volume: 117
Issue: 14
Pages: 8154-8165
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Publication
26601773 | J:237556
 
First Author: Duarte-Silva S
Year: 2016
Journal: Neuroscience
Title: Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease.
Volume: 313
Pages: 162-73
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Publication
38227368 | J:345723
 
First Author: Duarte-Silva S
Year: 2024
Journal: J Clin Invest
Title: Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3.
Volume: 134
Issue: 5
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Publication
25633985 | J:222893
First Author: Chatterjee A
Year: 2015
Journal: PLoS Genet
Title: The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
Volume: 11
Issue: 1
Pages: e1004749
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Publication
28223212 | J:309818
 
First Author: Rajamani K
Year: 2017
Journal: Neuropharmacology
Title: n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3.
Volume: 117
Pages: 434-446
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Protein
Q6NZB0
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
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Protein
A2ALF0
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
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Protein
F6QIL6
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
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Protein
A2ALF2
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
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Protein
A2ALF3
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
F6TQL3
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom