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Search results 201 to 300 out of 552 for Bace1

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Hits by Strain

Type Details Score
Protein Coding Gene
MGP_PahariEiJ_G0015018 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033287 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22049418 | J:177847
First Author: Giusti-Rodríguez P
Year: 2011
Journal: J Neurosci
Title: Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1).
Volume: 31
Issue: 44
Pages: 15751-6
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Publication
11224535 | J:67736
First Author: Luo Y
Year: 2001
Journal: Nat Neurosci
Title: Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
Volume: 4
Issue: 3
Pages: 231-2
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Publication
11406613 | J:77414
First Author: Roberds SL
Year: 2001
Journal: Hum Mol Genet
Title: BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Volume: 10
Issue: 12
Pages: 1317-24
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Publication
19287391 | J:149374
First Author: Loane DJ
Year: 2009
Journal: Nat Med
Title: Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury.
Volume: 15
Issue: 4
Pages: 377-9
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Publication
21933711 | J:179837
First Author: Devi L
Year: 2012
Journal: Neurobiol Dis
Title: Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice.
Volume: 45
Issue: 1
Pages: 417-24
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Publication
18945886 | J:144634
First Author: Varvel NH
Year: 2008
Journal: J Neurosci
Title: Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease.
Volume: 28
Issue: 43
Pages: 10786-93
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Publication
22249458 | J:318112
First Author: Park MH
Year: 2012
Journal: J Neuropathol Exp Neurol
Title: Mutant presenilin 2 increases β-secretase activity through reactive oxygen species-dependent activation of extracellular signal-regulated kinase.
Volume: 71
Issue: 2
Pages: 130-9
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Publication
26661166 | J:318355
First Author: Devraj K
Year: 2016
Journal: J Cereb Blood Flow Metab
Title: BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease.
Volume: 36
Issue: 7
Pages: 1281-94
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GXD Expression
GXD Expression
   
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 100 ug protein
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 2 ug protein
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 20 ug protein
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3640767
Assay Type: Western blot
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3640776
Age: embryonic day 14.0
Image: 1
Specimen Label: 80 ug protein
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3640779
Assay Type: Northern blot
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640781
Age: postnatal
Image: S1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3640779
Assay Type: Northern blot
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640781
Age: postnatal
Image: S1
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: -/-
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/+
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3640784
Assay Type: RT-PCR
Annotation Date: 2006-08-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3640788
Age: postnatal
Image: S2
Specimen Label: -/-
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6860351
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1665928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression was stronger in pyramidal cells.
Specimen Label: 2B
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2362026
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530800
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3518328
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: not shown
Detected: false
Specimen Num: 8
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•
GXD Expression
GXD Expression
 
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression was weaker in granular cells.
Specimen Label: 2B
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2F
Detected: true
Specimen Num: 7
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression is in oligodendrocytes.
Specimen Label: 2D
Detected: true
Specimen Num: 6
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Note: Expression was stronger in pyramidal cells.
Specimen Label: 2B
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6860351
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3518628
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: not shown
Detected: false
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2B
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal adult
Specimen Label: 2D
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6860351
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6860351
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (medial)
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6860344
Assay Type: RNA in situ
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6860351
Age: postnatal day 4
Specimen Label: P4 (lateral)
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
27517085 | J:237784
 
First Author: Cheng N
Year: 2016
Journal: eNeuro
Title: APP Overexpression Causes Aβ-Independent Neuronal Death through Intrinsic Apoptosis Pathway.
Volume: 3
Issue: 4
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•
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•
Publication
38311982 | J:345924
First Author: Hong J
Year: 2024
Journal: Glia
Title: PMP2 regulates myelin thickening and ATP production during remyelination.
Volume: 72
Issue: 5
Pages: 885-898
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Publication
24806669 | J:211050
First Author: Kallop DY
Year: 2014
Journal: J Neurosci
Title: A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.
Volume: 34
Issue: 19
Pages: 6425-37
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Publication
36716914 | J:347459
 
First Author: Murray HC
Year: 2023
Journal: Neuroscience
Title: Progressive Spread of Beta-amyloid Pathology in an Olfactory-driven Amyloid Precursor Protein Mouse Model.
Volume: 516
Pages: 113-124
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•
•
•
•
Publication
23931995 | J:266459
First Author: Das U
Year: 2013
Journal: Neuron
Title: Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.
Volume: 79
Issue: 3
Pages: 447-60
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•
•
•
•
Publication
26755586 | J:229925
First Author: Lee YI
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions.
Volume: 113
Issue: 4
Pages: E479-87
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Publication
28696204 | J:257152
   
First Author: Puzzo D
Year: 2017
Journal: Elife
Title: LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent.
Volume: 6
•
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•
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Publication
20097169 | J:158017
First Author: Jin S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Evidence for dimeric BACE-mediated APP processing.
Volume: 393
Issue: 1
Pages: 21-7
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•
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Publication
27576688 | J:237285
First Author: Qin X
Year: 2016
Journal: J Biol Chem
Title: Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the Brain.
Volume: 291
Issue: 42
Pages: 22276-22287
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Publication
21542009 | J:184350
First Author: Cui S
Year: 2011
Journal: J Bone Miner Res
Title: APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.
Volume: 26
Issue: 5
Pages: 1084-98
•
•
•
•
•
Publication
19683527 | J:152969
First Author: Philipson O
Year: 2009
Journal: FEBS Lett
Title: Genetic and pharmacological evidence of intraneuronal Abeta accumulation in APP transgenic mice.
Volume: 583
Issue: 18
Pages: 3021-6
•
•
•
•
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Publication
19907078 | J:155100
First Author: Varvel NH
Year: 2009
Journal: J Clin Invest
Title: NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.
Volume: 119
Issue: 12
Pages: 3692-702
•
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•
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•
Publication
26642089 | J:234437
First Author: Das U
Year: 2016
Journal: Nat Neurosci
Title: Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway.
Volume: 19
Issue: 1
Pages: 55-64
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Publication
30315100 | J:272882
First Author: Sadleir KR
Year: 2018
Journal: J Biol Chem
Title: ER stress is not elevated in the 5XFAD mouse model of Alzheimer's disease.
Volume: 293
Issue: 48
Pages: 18434-18443
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Publication
39042667 | J:361092
First Author: Rajani RM
Year: 2024
Journal: PLoS Biol
Title: Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease.
Volume: 22
Issue: 7
Pages: e3002727
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Publication
33311478 | J:306682
First Author: Wu Z
Year: 2020
Journal: Cell Death Dis
Title: Delta-secretase triggers Alzheimer's disease pathologies in wild-type hAPP/hMAPT double transgenic mice.
Volume: 11
Issue: 12
Pages: 1058
•
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•
Publication
15583033 | J:94845
First Author: Abad-Rodriguez J
Year: 2004
Journal: J Cell Biol
Title: Neuronal membrane cholesterol loss enhances amyloid peptide generation.
Volume: 167
Issue: 5
Pages: 953-60
•
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•
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Publication
20833873 | J:167784
First Author: Pavlov PF
Year: 2011
Journal: FASEB J
Title: Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein.
Volume: 25
Issue: 1
Pages: 78-88
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•
•
•
•
Publication
22843498 | J:187999
First Author: Rodrigues EM
Year: 2012
Journal: Hum Mol Genet
Title: Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects.
Volume: 21
Issue: 21
Pages: 4587-601
•
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•
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•
Publication
24827165 | J:357980
First Author: Liu CG
Year: 2014
Journal: Int J Mol Med
Title: MicroRNA-384 regulates both amyloid precursor protein and β-secretase expression and is a potential biomarker for Alzheimer's disease.
Volume: 34
Issue: 1
Pages: 160-6
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Publication
16407538 | J:104263
First Author: Spoelgen R
Year: 2006
Journal: J Neurosci
Title: Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
Volume: 26
Issue: 2
Pages: 418-28
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Publication
27565738 | J:255892
First Author: Yáñez MJ
Year: 2016
Journal: Biochim Biophys Acta
Title: c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease.
Volume: 1862
Issue: 11
Pages: 2158-2167
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Publication
19920078 | J:155566
First Author: Ono Y
Year: 2009
Journal: J Cell Sci
Title: Presenilin-1 acts via Id1 to regulate the function of muscle satellite cells in a gamma-secretase-independent manner.
Volume: 122
Issue: Pt 24
Pages: 4427-38
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Publication
21907142 | J:176653
First Author: Esterházy D
Year: 2011
Journal: Cell Metab
Title: Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.
Volume: 14
Issue: 3
Pages: 365-77
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Publication
15951428 | J:99874
First Author: Mastrangelo P
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases.
Volume: 102
Issue: 25
Pages: 8972-7
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Publication
37819761 | J:348582
First Author: Wu Y
Year: 2023
Journal: Cell Rep
Title: Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis.
Volume: 42
Issue: 10
Pages: 113240
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Publication
32408680 | J:304164
 
First Author: Bécot A
Year: 2020
Journal: Cells
Title: The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer’s Disease Models.
Volume: 9
Issue: 5
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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