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Search results 201 to 300 out of 2034 for Bcr

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Type Details Score
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
2263470 | -
First Author: Zhu QS
Year: 1990
Journal: Nucleic Acids Res
Title: Unique organization of the human BCR gene promoter.
Volume: 18
Issue: 23
Pages: 7119-25
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Protein
Q61223
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
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Allele
Bcr<em1Smoc> | MGI:7289449
Name: BCR activator of RhoGEF and GTPase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
20622883 | J:162389
First Author: Ubelhart R
Year: 2010
Journal: Nat Immunol
Title: N-linked glycosylation selectively regulates autonomous precursor BCR function.
Volume: 11
Issue: 8
Pages: 759-65
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Publication
29615403 | J:264755
First Author: Kuo PY
Year: 2018
Journal: Blood
Title: SOX11 augments BCR signaling to drive MCL-like tumor development.
Volume: 131
Issue: 20
Pages: 2247-2255
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Publication
24344237 | J:208364
First Author: Poe JC
Year: 2014
Journal: J Exp Med
Title: EndoU is a novel regulator of AICD during peripheral B cell selection.
Volume: 211
Issue: 1
Pages: 57-69
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Publication
28805811 | J:258712
First Author: Minguet S
Year: 2017
Journal: Nat Immunol
Title: Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.
Volume: 18
Issue: 10
Pages: 1150-1159
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Publication
18819072 | J:140162
First Author: Minguet S
Year: 2008
Journal: Eur J Immunol
Title: Enhanced B-cell activation mediated by TLR4 and BCR crosstalk.
Volume: 38
Issue: 9
Pages: 2475-87
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Publication
32999453 | J:343151
First Author: Tang CA
Year: 2021
Journal: Cell Mol Immunol
Title: STING regulates BCR signaling in normal and malignant B cells.
Volume: 18
Issue: 4
Pages: 1016-1031
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Publication
32252758 | J:315653
First Author: Du Z
Year: 2020
Journal: Cell Commun Signal
Title: AKT2 deficiency impairs formation of the BCR signalosome.
Volume: 18
Issue: 1
Pages: 56
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Publication
24493799 | J:208440
First Author: Avalos AM
Year: 2014
Journal: J Exp Med
Title: Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells.
Volume: 211
Issue: 2
Pages: 365-79
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Publication
32499646 | J:294096
First Author: Chen H
Year: 2020
Journal: Nature
Title: BCR selection and affinity maturation in Peyer's patch germinal centres.
Volume: 582
Issue: 7812
Pages: 421-425
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Allele
Bcr<tm1(BCR/ABL)Tsr> | MGI:5524984
 
Name: BCR activator of RhoGEF and GTPase; targeted mutation 1, Theodora S Ross
Allele Type: Targeted
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Publication
31157616 | J:277319
   
First Author: Bolger-Munro M
Year: 2019
Journal: Elife
Title: Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation.
Volume: 8
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Publication
12645942 | J:115705
First Author: Ulivieri C
Year: 2003
Journal: Eur J Immunol
Title: Normal B-1 cell development but defective BCR signaling in Lck-/- mice.
Volume: 33
Issue: 2
Pages: 441-5
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Publication
30936881 | J:294664
 
First Author: Łyszkiewicz M
Year: 2019
Journal: Front Immunol
Title: LAMTOR2 (p14) Controls B Cell Differentiation by Orchestrating Endosomal BCR Trafficking.
Volume: 10
Pages: 497
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Publication
33532715 | J:308563
First Author: Yam-Puc JC
Year: 2021
Journal: iScience
Title: Enhanced BCR signaling inflicts early plasmablast and germinal center B cell death.
Volume: 24
Issue: 2
Pages: 102038
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Strain
MGI:6428230 | C57BL/6JSmoc-Bcr<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
31262710 | J:289298
 
First Author: Wang C
Year: 2019
Journal: EBioMedicine
Title: Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response.
Volume: 45
Pages: 578-587
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Publication
25229630 | J:308832
First Author: Amin R
Year: 2014
Journal: Oncotarget
Title: The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model.
Volume: 5
Issue: 19
Pages: 8995-9006
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Publication
19607732 | J:151691
 
First Author: Murn J
Year: 2009
Journal: BMC Genomics
Title: A Myc-regulated transcriptional network controls B-cell fate in response to BCR triggering.
Volume: 10
Pages: 323
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Publication
8650582 | J:80885
First Author: Torres RM
Year: 1996
Journal: Science
Title: Aberrant B cell development and immune response in mice with a compromised BCR complex.
Volume: 272
Issue: 5269
Pages: 1804-8
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Publication
12118249 | J:109151
First Author: Su TT
Year: 2002
Journal: Nat Immunol
Title: PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.
Volume: 3
Issue: 8
Pages: 780-6
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Publication
28135254 | J:240689
First Author: Nguyen TT
Year: 2017
Journal: Nat Immunol
Title: The IgM receptor FcμR limits tonic BCR signaling by regulating expression of the IgM BCR.
Volume: 18
Issue: 3
Pages: 321-333
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Publication
26671981 | J:229686
First Author: Gasparrini F
Year: 2016
Journal: EMBO J
Title: Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling.
Volume: 35
Issue: 3
Pages: 258-80
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Publication
20139987 | J:158627
First Author: Capasso M
Year: 2010
Journal: Nat Immunol
Title: HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.
Volume: 11
Issue: 3
Pages: 265-72
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Publication
15186779 | J:91091
First Author: Kraus M
Year: 2004
Journal: Cell
Title: Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer.
Volume: 117
Issue: 6
Pages: 787-800
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Publication
28615655 | J:287412
First Author: Tsiantoulas D
Year: 2017
Journal: Sci Rep
Title: Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development.
Volume: 7
Issue: 1
Pages: 3540
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Publication
21708930 | J:176805
First Author: Kometani K
Year: 2011
Journal: J Exp Med
Title: CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway.
Volume: 208
Issue: 7
Pages: 1447-57
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Publication
23913047 | J:208233
First Author: Castello A
Year: 2013
Journal: Nat Immunol
Title: Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.
Volume: 14
Issue: 9
Pages: 966-75
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Publication
17673920 | J:141345
First Author: Avramidou A
Year: 2007
Journal: Cell Death Differ
Title: The novel adaptor protein Swiprosin-1 enhances BCR signals and contributes to BCR-induced apoptosis.
Volume: 14
Issue: 11
Pages: 1936-47
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Publication
21928281 | J:179511
First Author: Gross AJ
Year: 2011
Journal: Eur J Immunol
Title: Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.
Volume: 41
Issue: 12
Pages: 3645-55
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Publication
20176802 | J:158819
First Author: Rowland SL
Year: 2010
Journal: J Exp Med
Title: Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation.
Volume: 207
Issue: 3
Pages: 607-21
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Publication
28605013 | J:248486
First Author: Sacquin A
Year: 2017
Journal: Eur J Immunol
Title: The strength of BCR signaling shapes terminal development of follicular helper T cells in mice.
Volume: 47
Issue: 8
Pages: 1295-1304
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Publication
24080084 | J:207033
First Author: Zhang Y
Year: 2014
Journal: Int Immunol
Title: A role for CMTM7 in BCR expression and survival in B-1a but not B-2 cells.
Volume: 26
Issue: 1
Pages: 47-57
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Publication
11717190 | J:131633
First Author: Zou X
Year: 2001
Journal: Int Immunol
Title: Truncation of the mu heavy chain alters BCR signalling and allows recruitment of CD5+ B cells.
Volume: 13
Issue: 12
Pages: 1489-99
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Publication
32016488 | J:311707
First Author: Li N
Year: 2020
Journal: Cell Mol Life Sci
Title: CX3CR1 positively regulates BCR signaling coupled with cell metabolism via negatively controlling actin remodeling.
Volume: 77
Issue: 21
Pages: 4379-4395
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Publication
11254872 | J:68506
First Author: Heisterkamp N
Year: 2001
Journal: Int J Mol Med
Title: The Bcr N-terminal oligomerization domain contributes to the full oncogenicity of P190 Bcr/Abl in transgenic mice.
Volume: 7
Issue: 4
Pages: 351-7
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Publication
18792411 | J:141226
First Author: Zhu X
Year: 2008
Journal: Eur J Immunol
Title: Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling.
Volume: 38
Issue: 9
Pages: 2587-99
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Publication
19214191 | J:146814
First Author: Schmidt C
Year: 2009
Journal: EMBO J
Title: Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright.
Volume: 28
Issue: 6
Pages: 711-24
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Publication
22311635 | J:318957
First Author: Andrews SF
Year: 2012
Journal: Eur J Immunol
Title: Developmentally regulated expression of MEF2C limits the response to BCR engagement in transitional B cells.
Volume: 42
Issue: 5
Pages: 1327-36
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Publication
38732181 | J:348369
 
First Author: Zhao B
Year: 2024
Journal: Int J Mol Sci
Title: BAP31 Plays an Essential Role in Mouse B Cell Development via Regulation of BCR Signaling.
Volume: 25
Issue: 9
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Publication
21310073 | -
 
First Author: Yi SJ
Year: 2011
Journal: BMC Biochem
Title: Bcr is a substrate for Transglutaminase 2 cross-linking activity.
Volume: 12
Pages: 8
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Publication
12021782 | J:254163
First Author: Shih TA
Year: 2002
Journal: Nat Immunol
Title: Role of BCR affinity in T cell dependent antibody responses in vivo.
Volume: 3
Issue: 6
Pages: 570-5
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Pathway
R-MMU-5690714 | CD22 mediated BCR regulation
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Publication
1379745 | J:28608
First Author: Cicchetti P
Year: 1992
Journal: Science
Title: Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho.
Volume: 257
Issue: 5071
Pages: 803-6
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Publication
9586639 | J:110531
First Author: Cornall RJ
Year: 1998
Journal: Immunity
Title: Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.
Volume: 8
Issue: 4
Pages: 497-508
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Publication
28250425 | J:258170
First Author: Kreslavsky T
Year: 2017
Journal: Nat Immunol
Title: Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells.
Volume: 18
Issue: 4
Pages: 442-455
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Publication
19342645 | J:147739
First Author: Miller AT
Year: 2009
Journal: J Immunol
Title: Inositol 1,4,5-trisphosphate 3-kinase B is a negative regulator of BCR signaling that controls B cell selection and tolerance induction.
Volume: 182
Issue: 8
Pages: 4696-704
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Publication
31011187 | J:282639
First Author: Luo W
Year: 2019
Journal: Nat Immunol
Title: The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells.
Volume: 20
Issue: 6
Pages: 736-746
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Publication
11869685 | J:74717
First Author: Sun T
Year: 2002
Journal: Immunity
Title: A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
Volume: 16
Issue: 2
Pages: 245-55
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Publication
15357954 | J:93928
First Author: Dal Porto JM
Year: 2004
Journal: Immunity
Title: Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck.
Volume: 21
Issue: 3
Pages: 443-53
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Publication
27550373 | J:249783
First Author: Manno B
Year: 2016
Journal: Eur J Immunol
Title: The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner.
Volume: 46
Issue: 11
Pages: 2520-2530
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Publication
30833793 | J:282654
First Author: Biram A
Year: 2019
Journal: Nat Immunol
Title: BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer's patches.
Volume: 20
Issue: 4
Pages: 482-492
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Strain
MGI:5525088 | C57BL/6-Bcr<tm1(BCR/ABL)Tsr>
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:5524285 | C57BL/6-Bcr<tm1(BCR/ABL)Tsr>/J
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
15569774 | J:94796
First Author: Caucheteux SM
Year: 2005
Journal: Int Immunol
Title: Pregnancy-induced alterations of B cell maturation and survival are differentially affected by Fas and Bcl-2, independently of BcR expression.
Volume: 17
Issue: 1
Pages: 55-63
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Publication
23457006 | J:198141
First Author: Guo B
Year: 2013
Journal: Eur J Immunol
Title: A novel Lyn-protein kinase Cδ/ε-protein kinase D axis is activated in B cells by signalosome-independent alternate pathway BCR signaling.
Volume: 43
Issue: 6
Pages: 1643-50
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Publication
16114097 | J:113491
First Author: Glassford J
Year: 2005
Journal: Eur J Immunol
Title: Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.
Volume: 35
Issue: 9
Pages: 2748-61
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Publication
14517273 | J:86002
First Author: Enders A
Year: 2003
Journal: J Exp Med
Title: Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells.
Volume: 198
Issue: 7
Pages: 1119-26
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Publication
16801401 | J:124402
First Author: Bléry M
Year: 2006
Journal: J Exp Med
Title: Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy.
Volume: 203
Issue: 7
Pages: 1773-83
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Publication
25564405 | J:221921
First Author: Iacovelli S
Year: 2015
Journal: Blood
Title: Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.
Volume: 125
Issue: 10
Pages: 1578-88
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Publication
20861359 | J:164719
First Author: Rowland SL
Year: 2010
Journal: J Immunol
Title: BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling.
Volume: 185
Issue: 8
Pages: 4570-81
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Publication
32305130 | J:319396
 
First Author: Liu Z
Year: 2020
Journal: Cell Immunol
Title: Essential role for Cmtm7 in cell-surface phenotype, BCR signaling, survival and Igμ repertoire of splenic B-1a cells.
Volume: 352
Pages: 104100
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Publication
17312134 | J:144109
First Author: Sato M
Year: 2007
Journal: J Immunol
Title: Augmentation of signaling through BCR containing IgE but not that containing IgA due to lack of CD22-mediated signal regulation.
Volume: 178
Issue: 5
Pages: 2901-7
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Publication
28199836 | J:254515
First Author: Kuraoka M
Year: 2017
Journal: Cell Rep
Title: BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance.
Volume: 18
Issue: 7
Pages: 1627-1635
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Publication
11932924 | J:75975
First Author: Yachimovich N
Year: 2002
Journal: Eur J Immunol
Title: The efficiency of B cell receptor (BCR) editing is dependent on BCR light chain rearrangement status.
Volume: 32
Issue: 4
Pages: 1164-74
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Publication
24526714 | J:209145
First Author: Falk L
Year: 2014
Journal: Biol Open
Title: Mutations of Cx43 that affect B cell spreading in response to BCR signaling.
Volume: 3
Issue: 3
Pages: 185-94
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Genotype
Genotype
Symbol: Bcr/Bcr<+>
Background: C57BL/6-Bcr
Zygosity: ht
Has Mutant Allele: true
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Publication
16278813 | J:113739
First Author: Ferry H
Year: 2005
Journal: Eur J Immunol
Title: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival.
Volume: 35
Issue: 12
Pages: 3655-63
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Publication
8246975 | -
First Author: McWhirter JR
Year: 1993
Journal: Mol Cell Biol
Title: A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins.
Volume: 13
Issue: 12
Pages: 7587-95
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Publication
23267016 | J:194663
First Author: Bergmann H
Year: 2013
Journal: J Exp Med
Title: B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.
Volume: 210
Issue: 1
Pages: 31-40
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Allele
Bcr<+> | MGI:2430061
   
Name: BCR activator of RhoGEF and GTPase; wild type
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Allele
Bcr<Gt(YHC044)Byg> | MGI:3876181
 
Name: BCR activator of RhoGEF and GTPase; gene trap YHC044, BayGenomics
Allele Type: Gene trapped
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Allele
Bcr<Gt(RRA019)Byg> | MGI:4124626
 
Name: BCR activator of RhoGEF and GTPase; gene trap RRA019, BayGenomics
Allele Type: Gene trapped
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Allele
Bcr<Gt(RRO181)Byg> | MGI:4329363
 
Name: BCR activator of RhoGEF and GTPase; gene trap RRO181, BayGenomics
Allele Type: Gene trapped
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Allele
Bcr<Gt(RRR173)Byg> | MGI:4330713
 
Name: BCR activator of RhoGEF and GTPase; gene trap RRR173, BayGenomics
Allele Type: Gene trapped
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Publication
35081339 | J:322570
First Author: Ghosh D
Year: 2022
Journal: Cell Rep
Title: Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells.
Volume: 38
Issue: 4
Pages: 110200
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Publication
29312329 | J:267437
 
First Author: Castiblanco DP
Year: 2017
Journal: Front Immunol
Title: Co-Stimulation of BCR and Toll-Like Receptor 7 Increases Somatic Hypermutation, Memory B Cell Formation, and Secondary Antibody Response to Protein Antigen.
Volume: 8
Pages: 1833
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Publication
11809737 | J:74619
First Author: Inui S
Year: 2002
Journal: Int Immunol
Title: BCR signal through alpha 4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation.
Volume: 14
Issue: 2
Pages: 177-87
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HT Experiment
E-MTAB-10061 | Single-cell genomics reveals the peritoneal B1 cell development pathway and uncovers its BCR repertoire evolution in aging
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Publication
17404251 | J:145207
First Author: Guo B
Year: 2007
Journal: J Immunol
Title: Cutting Edge: B cell receptor (BCR) cross-talk: the IL-4-induced alternate pathway for BCR signaling operates in parallel with the classical pathway, is sensitive to Rottlerin, and depends on Lyn.
Volume: 178
Issue: 8
Pages: 4726-30
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Publication
16860389 | J:113218
First Author: Volgina VV
Year: 2007
Journal: Mol Immunol
Title: Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain.
Volume: 44
Issue: 6
Pages: 1417-28
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GO Term
GO:0032595 | B cell receptor transport within lipid bilayer
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GO Term
GO:0036300 | B cell receptor internalization
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Gene Segment
MGI:96448 | Ighm
Type: gene_segment
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Bcr/Bcr Tg(Vav1-cre)#Cgp/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Allele
Bcr<tm1Hkp> | MGI:2154396
Name: BCR activator of RhoGEF and GTPase; targeted mutation 1, Nora Heisterkamp
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Bcr<Gt(PST13827)Mfgc> | MGI:3862855
 
Name: BCR activator of RhoGEF and GTPase; gene trap PST13827, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Allele
Bcr<Gt(E063C04)Wrst> | MGI:3894876
 
Name: BCR activator of RhoGEF and GTPase; gene trap E063C04, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Bcr<tm1(KOMP)Wtsi> | MGI:4419256
Name: BCR activator of RhoGEF and GTPase; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Bcr<Gt(EUCJ0019g11)Hmgu> | MGI:4871153
 
Name: BCR activator of RhoGEF and GTPase; gene trap EUCJ0019g11, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Bcr<em10Gpt> | MGI:7295878
Name: BCR activator of RhoGEF and GTPase; endonuclease-mediated mutation 10, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Bcr<em1Gpt> | MGI:7295879
Name: BCR activator of RhoGEF and GTPase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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