|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 237 out of 237 for Birc2

<< First    < Previous  |  Next >    Last >>
0.02s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Allele
Birc2<em1Smoc> | MGI:7288482
Name: baculoviral IAP repeat-containing 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Protein
Q62210
Organism: Mus musculus/domesticus
Length: 612  
Fragment?: false
•
•
•
•
•
Strain
MGI:6428236 | C57BL/6JSmoc-Birc2<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Allele
Birc2<em1Haka> | MGI:7560637
 
Name: baculoviral IAP repeat-containing 2; endonuclease-mediated mutation 1, Hamid Kashkar
Allele Type: Endonuclease-mediated
•
•
•
•
•
Allele
Birc3<em1Haka> | MGI:7560638
 
Name: baculoviral IAP repeat-containing 3; endonuclease-mediated mutation 1, Hamid Kashkar
Allele Type: Endonuclease-mediated
•
•
•
•
•
Publication
26872784 | J:249864
First Author: Zhang L
Year: 2016
Journal: J Cell Sci
Title: TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice.
Volume: 129
Issue: 7
Pages: 1455-67
•
•
•
•
•
Publication
18414036 | J:182490
First Author: Dubrez-Daloz L
Year: 2008
Journal: Cell Cycle
Title: IAPs: more than just inhibitors of apoptosis proteins.
Volume: 7
Issue: 8
Pages: 1036-46
•
•
•
•
•
Protein
F7BQL8
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
•
•
•
•
•
Publication
19153467 | -
First Author: Kulathila R
Year: 2009
Journal: Acta Crystallogr D Biol Crystallogr
Title: The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9.
Volume: 65
Issue: Pt 1
Pages: 58-66
•
•
•
•
•
Publication
22021857 | -
First Author: Dueber EC
Year: 2011
Journal: Science
Title: Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.
Volume: 334
Issue: 6054
Pages: 376-80
•
•
•
•
•
Publication
21447281 | -
First Author: Damgaard RB
Year: 2011
Journal: Discov Med
Title: Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity.
Volume: 11
Issue: 58
Pages: 221-31
•
•
•
•
•
Publication
21653699 | -
First Author: Cartier J
Year: 2011
Journal: J Biol Chem
Title: Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription.
Volume: 286
Issue: 30
Pages: 26406-17
•
•
•
•
•
Protein Domain
IPR041933 | BIRC2/BIRC3_UBA
Type: Domain
Description: The entry represents the UBA domain found in c-IAPs, including BIRC2 (also known as C-IAP1) and BIRC3 (also known as C-IAP2). c-IAPs function as ubiquitin E3 ligases that mediate the ubiquitination of the substrates involved in apoptosis, nuclear factor-kappaB (NF-kappaB) signaling, and oncogenesis [, ]. Unlike other apoptosis proteins such as XIAP, c-IAPs exhibit minimal binding to caspases and may not play an important role in the inhibition of these proteases. c-IAP1 is a potent regulator of the tumor necrosis factor (TNF) receptor family and NF-kappaB signaling pathways in the cytoplasm. It can also regulate E2F1 transcription factor-mediated control of cyclin transcription in the nucleus []. c-IAP2 also influences ubiquitin-dependent pathways that modulate innate immune signalling by activation of NF-kappaB []. c-IAPs contain three N-terminal baculoviral IAP repeat (BIR) domains that enable interactions with proteins, a ubiquitin-association (UBA) domain that is responsible for the binding of polyubiquitin (polyUb), a caspase activation and recruitment domain (CARD) that serves as a protein interaction surface, and a RING domain at the carboxyl terminus that is required for ubiquitin ligase activity [, ].
•
•
•
•
•
Publication
20651737 | -
First Author: Gyrd-Hansen M
Year: 2010
Journal: Nat Rev Cancer
Title: IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.
Volume: 10
Issue: 8
Pages: 561-74
•
•
•
•
•
Protein
Q3T9B6
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: true
•
•
•
•
•
Protein
Q3TSE5
Organism: Mus musculus/domesticus
Length: 545  
Fragment?: true
•
•
•
•
•
Protein
O08863
Organism: Mus musculus/domesticus
Length: 600  
Fragment?: false
•
•
•
•
•
Protein
A2CGA5
Organism: Mus musculus/domesticus
Length: 602  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom