| Type |
Details |
Score |
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Allele |
| Name: |
baculoviral IAP repeat-containing 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
612
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
baculoviral IAP repeat-containing 2; endonuclease-mediated mutation 1, Hamid Kashkar |
| Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
baculoviral IAP repeat-containing 3; endonuclease-mediated mutation 1, Hamid Kashkar |
| Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
2016 |
| Journal: |
J Cell Sci |
| Title: |
TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice. |
| Volume: |
129 |
| Issue: |
7 |
| Pages: |
1455-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dubrez-Daloz L |
| Year: |
2008 |
| Journal: |
Cell Cycle |
| Title: |
IAPs: more than just inhibitors of apoptosis proteins. |
| Volume: |
7 |
| Issue: |
8 |
| Pages: |
1036-46 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
138
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kulathila R |
| Year: |
2009 |
| Journal: |
Acta Crystallogr D Biol Crystallogr |
| Title: |
The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9. |
| Volume: |
65 |
| Issue: |
Pt 1 |
| Pages: |
58-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dueber EC |
| Year: |
2011 |
| Journal: |
Science |
| Title: |
Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. |
| Volume: |
334 |
| Issue: |
6054 |
| Pages: |
376-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Damgaard RB |
| Year: |
2011 |
| Journal: |
Discov Med |
| Title: |
Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity. |
| Volume: |
11 |
| Issue: |
58 |
| Pages: |
221-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cartier J |
| Year: |
2011 |
| Journal: |
J Biol Chem |
| Title: |
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription. |
| Volume: |
286 |
| Issue: |
30 |
| Pages: |
26406-17 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
The entry represents the UBA domain found in c-IAPs, including BIRC2 (also known as C-IAP1) and BIRC3 (also known as C-IAP2). c-IAPs function as ubiquitin E3 ligases that mediate the ubiquitination of the substrates involved in apoptosis, nuclear factor-kappaB (NF-kappaB) signaling, and oncogenesis [, ]. Unlike other apoptosis proteins such as XIAP, c-IAPs exhibit minimal binding to caspases and may not play an important role in the inhibition of these proteases. c-IAP1 is a potent regulator of the tumor necrosis factor (TNF) receptor family and NF-kappaB signaling pathways in the cytoplasm. It can also regulate E2F1 transcription factor-mediated control of cyclin transcription in the nucleus []. c-IAP2 also influences ubiquitin-dependent pathways that modulate innate immune signalling by activation of NF-kappaB []. c-IAPs contain three N-terminal baculoviral IAP repeat (BIR) domains that enable interactions with proteins, a ubiquitin-association (UBA) domain that is responsible for the binding of polyubiquitin (polyUb), a caspase activation and recruitment domain (CARD) that serves as a protein interaction surface, and a RING domain at the carboxyl terminus that is required for ubiquitin ligase activity [, ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gyrd-Hansen M |
| Year: |
2010 |
| Journal: |
Nat Rev Cancer |
| Title: |
IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. |
| Volume: |
10 |
| Issue: |
8 |
| Pages: |
561-74 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
542
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
545
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
600
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
602
 |
| Fragment?: |
false |
|
•
•
•
•
•
|