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Search results 201 to 271 out of 271 for Bmp15

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Type Details Score
Publication
20702851 | J:168363
First Author: Sugiura K
Year: 2010
Journal: Biol Reprod
Title: Does bone morphogenetic protein 6 (BMP6) affect female fertility in the mouse?
Volume: 83
Issue: 6
Pages: 997-1004
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Publication
21047911 | J:182909
First Author: Sugiura K
Year: 2010
Journal: Mol Endocrinol
Title: Estrogen promotes the development of mouse cumulus cells in coordination with oocyte-derived GDF9 and BMP15.
Volume: 24
Issue: 12
Pages: 2303-14
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Publication
25416550 | J:218520
First Author: Grasa P
Year: 2015
Journal: FASEB J
Title: Oocytes lacking O-glycans alter follicle development and increase fertility by increasing follicle FSH sensitivity, decreasing apoptosis, and modifying GDF9:BMP15 expression.
Volume: 29
Issue: 2
Pages: 525-39
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Publication
12912906 | J:85054
First Author: Lan ZJ
Year: 2003
Journal: EMBO J
Title: GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility.
Volume: 22
Issue: 16
Pages: 4070-81
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Publication
19480014 | J:200667
First Author: Monti M
Year: 2009
Journal: Mol Reprod Dev
Title: Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.
Volume: 76
Issue: 10
Pages: 994-1003
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Publication
20382892 | J:162255
First Author: Su YQ
Year: 2010
Journal: Mol Endocrinol
Title: Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling.
Volume: 24
Issue: 6
Pages: 1230-9
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Publication
12887271 | J:85566
First Author: Lin SY
Year: 2003
Journal: Reproduction
Title: Regulation of ovarian function by the TGF-beta superfamily and follistatin.
Volume: 126
Issue: 2
Pages: 133-48
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Publication
26267271 | J:226026
First Author: Deuve JL
Year: 2015
Journal: Epigenetics
Title: Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome.
Volume: 10
Issue: 10
Pages: 931-42
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Publication
35104175 | J:324293
First Author: Gindi N
Year: 2022
Journal: Cell Cycle
Title: Fyn and argonaute 2 participate in maternal-mRNA degradation during mouse oocyte maturation.
Volume: 21
Issue: 8
Pages: 792-804
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Publication
22847922 | J:190579
First Author: Pangas SA
Year: 2012
Journal: Mol Reprod Dev
Title: Regulation of the ovarian reserve by members of the transforming growth factor beta family.
Volume: 79
Issue: 10
Pages: 666-79
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Publication
31657143 | J:282136
First Author: Kato Y
Year: 2019
Journal: EMBO Rep
Title: ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
Volume: 20
Issue: 12
Pages: e48251
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Publication
32685006 | J:356109
First Author: Ge W
Year: 2020
Journal: Theranostics
Title: Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development.
Volume: 10
Issue: 17
Pages: 7581-7598
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Publication
16933306 | J:356549
First Author: Mukhopadhyay P
Year: 2006
Journal: Birth Defects Res A Clin Mol Teratol
Title: Expression profiling of transforming growth factor beta superfamily genes in developing orofacial tissue.
Volume: 76
Issue: 7
Pages: 528-43
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Publication
15326356 | J:92421
First Author: Rajkovic A
Year: 2004
Journal: Science
Title: NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.
Volume: 305
Issue: 5687
Pages: 1157-9
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Publication
25810521 | J:221341
First Author: Lun MP
Year: 2015
Journal: J Neurosci
Title: Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.
Volume: 35
Issue: 12
Pages: 4903-16
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Publication
24357321 | J:205485
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
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Publication
15342483 | J:108109
First Author: Oxburgh L
Year: 2004
Journal: Development
Title: TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.
Volume: 131
Issue: 18
Pages: 4593-605
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Publication
30352686 | J:270543
First Author: Tanahashi H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of Lrp4 increases the incidence of microphthalmia.
Volume: 506
Issue: 3
Pages: 478-484
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Publication
12666204 | J:82773
First Author: Dichmann DS
Year: 2003
Journal: Dev Dyn
Title: Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas.
Volume: 226
Issue: 4
Pages: 663-74
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Publication
16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Bmp15<em1Ksjq> | MGI:7658873
Name: bone morphogenetic protein 15; endonuclease-mediated mutation 1, Shan Kang
Allele Type: Endonuclease-mediated
Attribute String: Hypomorph
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DO Term
DOID:0080494 | ovarian dysgenesis 2
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DO Term
DOID:0080861 | primary ovarian insufficiency 4
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Publication
10443672 | -
First Author: Aaltonen J
Year: 1999
Journal: J Clin Endocrinol Metab
Title: Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early folliculogenesis.
Volume: 84
Issue: 8
Pages: 2744-50
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Publication
10998422 | -
First Author: Otsuka F
Year: 2000
Journal: J Biol Chem
Title: Bone morphogenetic protein-15. Identification of target cells and biological functions.
Volume: 275
Issue: 50
Pages: 39523-8
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Protein Domain
IPR015923 | BMP-15
Type: Family
Description: The bone morphogenetic protein (BMP) is part of the transforming growth factor-beta superfamily. Transforming growth factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. TGF-beta-1 is a peptide of 112 amino acid residues derived by proteolytic cleavage from the C-terminal of a precursor protein.A number of proteins are known to be related to TGF-beta-1 [, ]. Proteins from the TGF-beta family are only active as homo- or heterodimer; the two chains being linked by a single disulphide bond. From X-ray studies of TGF-beta-2 [], it is known that all the other cysteines are involved in intrachain disulphide bonds. As shown in the following schematic representation, there are four disulphide bonds in the TGF-beta's and in inhibin beta chains, while the other members of lack the first bond.BMP-15 (or GDF-9B) has been identified by in the mouse and in humans []. BMP15 protein is encoded by 2 exons []. Homo sapiens (Human) GDF9B transcripts could be detected only in the gonads by RT-PCR analysis, and in situ hybridization studies indicated that GDF9B is not expressed in small primary follicles but rather in the oocytes of late primary follicles []. It was shown that BMP15 is a selective modulator of FSH function []. Male BMP-15 knockout mice are normal and fertile while the females demonstrate decreased ovulation and fertilization rate [].
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HT Experiment
E-GEOD-7225 | Transcription profiling of mouse cumulus cells from Bmp15-/- and Bmp15-/-Gdf9+/--DM animals
Series Id: GSE7225
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
30010909 | J:266539
First Author: Zhang D
Year: 2018
Journal: Hum Mol Genet
Title: Basonuclin 1 deficiency is a cause of primary ovarian insufficiency.
Volume: 27
Issue: 21
Pages: 3787-3800
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Publication
26388295 | J:250114
 
First Author: Tokuhiro K
Year: 2015
Journal: Sci Rep
Title: Calreticulin is required for development of the cumulus oocyte complex and female fertility.
Volume: 5
Pages: 14254
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Publication
16011810 | J:123873
 
First Author: Turk R
Year: 2005
Journal: BMC Genomics
Title: Muscle regeneration in dystrophin-deficient mdx mice studied by gene expression profiling.
Volume: 6
Pages: 98
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Publication
26040669 | J:224465
First Author: Sun T
Year: 2015
Journal: Biol Reprod
Title: Lats1 Deletion Causes Increased Germ Cell Apoptosis and Follicular Cysts in Mouse Ovaries.
Volume: 93
Issue: 1
Pages: 22
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Publication
18308851 | J:136039
First Author: McMahon HE
Year: 2008
Journal: Endocrinology
Title: Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice.
Volume: 149
Issue: 6
Pages: 2807-15
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Publication
19106224 | J:151812
First Author: Nicholls PK
Year: 2009
Journal: Endocrinology
Title: Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function.
Volume: 150
Issue: 5
Pages: 2481-90
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Publication
25253739 | J:218422
First Author: Peng J
Year: 2014
Journal: Biol Reprod
Title: Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities.
Volume: 91
Issue: 6
Pages: 142
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Protein
Q9Z0L4
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Q3USZ3
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Q3UWT0
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: true
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Publication
25099774 | J:310290
First Author: Schneider A
Year: 2014
Journal: Age (Dordr)
Title: Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.
Volume: 36
Issue: 4
Pages: 9701
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Publication
1575734 | -
First Author: Burt DW
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Evolutionary grouping of the transforming growth factor-beta superfamily.
Volume: 184
Issue: 2
Pages: 590-5
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Publication
8199356 | -
First Author: Burt DW
Year: 1994
Journal: Prog Growth Factor Res
Title: Evolution of the transforming growth factor-beta superfamily.
Volume: 5
Issue: 1
Pages: 99-118
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Publication
1631557 | -
First Author: Daopin S
Year: 1992
Journal: Science
Title: Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily.
Volume: 257
Issue: 5068
Pages: 369-73
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