Type |
Details |
Score |
Publication |
First Author: |
Qin X |
Year: |
2009 |
Journal: |
Am J Hematol |
Title: |
Generation and phenotyping of mCd59a and mCd59b double-knockout mice. |
Volume: |
84 |
Issue: |
2 |
Pages: |
65-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin X |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Further characterization of reproductive abnormalities in mCd59b knockout mice: a potential new function of mCd59 in male reproduction. |
Volume: |
175 |
Issue: |
10 |
Pages: |
6294-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hietala MA |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Complement deficiency ameliorates collagen-induced arthritis in mice. |
Volume: |
169 |
Issue: |
1 |
Pages: |
454-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossi O |
Year: |
2019 |
Journal: |
Immunology |
Title: |
The essential role of complement in antibody-mediated resistance to Salmonella. |
Volume: |
156 |
Issue: |
1 |
Pages: |
69-73 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1663
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Merle NS |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner. |
Volume: |
116 |
Issue: |
13 |
Pages: |
6280-6285 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tüzün E |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis. |
Volume: |
171 |
Issue: |
7 |
Pages: |
3847-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quigg RJ |
Year: |
1998 |
Journal: |
Kidney Int |
Title: |
Immune complex glomerulonephritis in C4- and C3-deficient mice. |
Volume: |
53 |
Issue: |
2 |
Pages: |
320-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Twohig J |
Year: |
2007 |
Journal: |
Mol Immunol |
Title: |
Defective B cell ontogeny and immune response in human complement receptor 2 (CR2, CD21) transgenic mice is partially recovered in the absence of C3. |
Volume: |
44 |
Issue: |
13 |
Pages: |
3434-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magliarelli HF |
Year: |
2016 |
Journal: |
Cell Death Dis |
Title: |
Liver ubiquitome uncovers nutrient-stress-mediated trafficking and secretion of complement C3. |
Volume: |
7 |
Issue: |
10 |
Pages: |
e2411 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hébert MJ |
Year: |
1998 |
Journal: |
Nephrol Dial Transplant |
Title: |
Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria. |
Volume: |
13 |
Issue: |
11 |
Pages: |
2799-803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morrison TE |
Year: |
2008 |
Journal: |
J Virol |
Title: |
Complement receptor 3 promotes severe ross river virus-induced disease. |
Volume: |
82 |
Issue: |
22 |
Pages: |
11263-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin D |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Evidence for an important interaction between a complement-derived CD21 ligand on follicular dendritic cells and CD21 on B cells in the initiation of IgG responses. |
Volume: |
161 |
Issue: |
9 |
Pages: |
4549-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berg A |
Year: |
2012 |
Journal: |
Exp Neurol |
Title: |
Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3. |
Volume: |
237 |
Issue: |
1 |
Pages: |
8-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sylvestre D |
Year: |
1996 |
Journal: |
J Exp Med |
Title: |
Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice. |
Volume: |
184 |
Issue: |
6 |
Pages: |
2385-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim YJ |
Year: |
2017 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Roles of antibodies to influenza A virus hemagglutinin, neuraminidase, and M2e in conferring cross protection. |
Volume: |
493 |
Issue: |
1 |
Pages: |
393-398 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheerin NS |
Year: |
1997 |
Journal: |
Clin Exp Immunol |
Title: |
Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice. |
Volume: |
110 |
Issue: |
3 |
Pages: |
403-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
The protective role of CD59 and pathogenic role of complement in hepatic ischemia and reperfusion injury. |
Volume: |
179 |
Issue: |
6 |
Pages: |
2876-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu F |
Year: |
2016 |
Journal: |
J Neuroinflammation |
Title: |
Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain. |
Volume: |
13 |
|
Pages: |
23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams JP |
Year: |
1999 |
Journal: |
J Appl Physiol (1985) |
Title: |
Intestinal reperfusion injury is mediated by IgM and complement. |
Volume: |
86 |
Issue: |
3 |
Pages: |
938-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
IgG3-antigen complexes are deposited on follicular dendritic cells in the presence of C1q and C3. |
Volume: |
7 |
Issue: |
1 |
Pages: |
5400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stevens B |
Year: |
2007 |
Journal: |
Cell |
Title: |
The classical complement cascade mediates CNS synapse elimination. |
Volume: |
131 |
Issue: |
6 |
Pages: |
1164-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Silverman SM |
Year: |
2019 |
Journal: |
J Exp Med |
Title: |
C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa. |
Volume: |
216 |
Issue: |
8 |
Pages: |
1925-1943 |
|
•
•
•
•
•
|
Publication |
First Author: |
Veremeyko T |
Year: |
2023 |
Journal: |
Front Cell Neurosci |
Title: |
Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes. |
Volume: |
17 |
|
Pages: |
1170031 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren J |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
Crosstalk between coagulation and complement activation promotes cardiac dysfunction in arrhythmogenic right ventricular cardiomyopathy. |
Volume: |
11 |
Issue: |
12 |
Pages: |
5939-5954 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crowley MA |
Year: |
2018 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Induction of Ocular Complement Activation by Inflammatory Stimuli and Intraocular Inhibition of Complement Factor D in Animal Models. |
Volume: |
59 |
Issue: |
2 |
Pages: |
940-951 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borkowska S |
Year: |
2013 |
Journal: |
Leukemia |
Title: |
Mobilization studies in C3-deficient mice unravel the involvement of a novel crosstalk between the coagulation and complement cascades in mobilization of hematopoietic stem/progenitor cells. |
Volume: |
27 |
Issue: |
9 |
Pages: |
1928-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao L |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy. |
Volume: |
179 |
Issue: |
3 |
Pages: |
1265-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baśkiewicz-Hałasa M |
Year: |
2015 |
Journal: |
Exp Hematol |
Title: |
Mixed chimerism and transplant tolerance are not effectively induced in C3a-deficient mice. |
Volume: |
43 |
Issue: |
1 |
Pages: |
14-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheerin NS |
Year: |
1999 |
Journal: |
Immunology |
Title: |
Altered distribution of intraglomerular immune complexes in C3-deficient mice. |
Volume: |
97 |
Issue: |
3 |
Pages: |
393-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bykov I |
Year: |
2007 |
Journal: |
Clin Immunol |
Title: |
Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver. |
Volume: |
124 |
Issue: |
2 |
Pages: |
213-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bodea LG |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Neurodegeneration by activation of the microglial complement-phagosome pathway. |
Volume: |
34 |
Issue: |
25 |
Pages: |
8546-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hod EA |
Year: |
2008 |
Journal: |
Blood |
Title: |
Cytokine storm in a mouse model of IgG-mediated hemolytic transfusion reactions. |
Volume: |
112 |
Issue: |
3 |
Pages: |
891-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan GS |
Year: |
2016 |
Journal: |
PLoS Pathog |
Title: |
Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection. |
Volume: |
12 |
Issue: |
4 |
Pages: |
e1005578 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seregin SS |
Year: |
2010 |
Journal: |
Blood |
Title: |
Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo. |
Volume: |
116 |
Issue: |
10 |
Pages: |
1669-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu S |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Helicobacter pylori initiates successful gastric colonization by utilizing L-lactate to promote complement resistance. |
Volume: |
14 |
Issue: |
1 |
Pages: |
1695 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koch CA |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
Complement-dependent control of teratoma formation by embryonic stem cells. |
Volume: |
177 |
Issue: |
7 |
Pages: |
4803-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao X |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Resistance to Streptozotocin-Induced Autoimmune Diabetes in Absence of Complement C3: Myeloid-Derived Suppressor Cells Play a Role. |
Volume: |
8 |
Issue: |
6 |
Pages: |
e66334 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wysoczynski M |
Year: |
2007 |
Journal: |
Leukemia |
Title: |
Cleavage fragments of the third complement component (C3) enhance stromal derived factor-1 (SDF-1)-mediated platelet production during reactive postbleeding thrombocytosis. |
Volume: |
21 |
Issue: |
5 |
Pages: |
973-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2012 |
Journal: |
Blood |
Title: |
Mesenchymal stem cells are injured by complement after their contact with serum. |
Volume: |
120 |
Issue: |
17 |
Pages: |
3436-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pekna M |
Year: |
1998 |
Journal: |
Scand J Immunol |
Title: |
Targeted disruption of the murine gene coding for the third complement component (C3). |
Volume: |
47 |
Issue: |
1 |
Pages: |
25-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SH |
Year: |
2008 |
Journal: |
Infect Immun |
Title: |
Recruitment of Rab27a to phagosomes controls microbial antigen cross-presentation by dendritic cells. |
Volume: |
76 |
Issue: |
11 |
Pages: |
5373-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun H |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Bacteria reduce flagellin synthesis to evade microglia-astrocyte-driven immunity in the brain. |
Volume: |
40 |
Issue: |
1 |
Pages: |
111033 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson DR |
Year: |
2007 |
Journal: |
Cardiovasc Res |
Title: |
The role of complement in the adherence of microbubbles to dysfunctional arterial endothelium and atherosclerotic plaque. |
Volume: |
73 |
Issue: |
3 |
Pages: |
597-606 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu J |
Year: |
2016 |
Journal: |
Blood |
Title: |
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice. |
Volume: |
128 |
Issue: |
26 |
Pages: |
3159-3168 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xavier S |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis. |
Volume: |
312 |
Issue: |
3 |
Pages: |
F516-F532 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ito K |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Lack of galactosylation enhances the pathogenic activity of IgG1 but Not IgG2a anti-erythrocyte autoantibodies. |
Volume: |
192 |
Issue: |
2 |
Pages: |
581-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi K |
Year: |
2005 |
Journal: |
Infect Immun |
Title: |
Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection. |
Volume: |
73 |
Issue: |
12 |
Pages: |
8188-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mener A |
Year: |
2018 |
Journal: |
JCI Insight |
Title: |
Complement serves as a switch between CD4+ T cell-independent and -dependent RBC antibody responses. |
Volume: |
3 |
Issue: |
22 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Linder AT |
Year: |
2022 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Sialic acids on B cells are crucial for their survival and provide protection against apoptosis. |
Volume: |
119 |
Issue: |
25 |
Pages: |
e2201129119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorelik A |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Developmental activities of the complement pathway in migrating neurons. |
Volume: |
8 |
|
Pages: |
15096 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berg A |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
The extent of synaptic stripping of motoneurons after axotomy is not correlated to activation of surrounding glia or downregulation of postsynaptic adhesion molecules. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e59647 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imai M |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer. |
Volume: |
65 |
Issue: |
22 |
Pages: |
10562-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ratajczak MZ |
Year: |
2004 |
Journal: |
Leukemia |
Title: |
Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells. |
Volume: |
18 |
Issue: |
9 |
Pages: |
1482-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kohn M |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Complement and Chlamydia psittaci: Early Complement-Dependent Events Are Important for DC Migration and Protection During Mouse Lung Infection. |
Volume: |
12 |
|
Pages: |
580594 |
|
•
•
•
•
•
|
Publication |
First Author: |
Riley SP |
Year: |
2018 |
Journal: |
Infect Immun |
Title: |
Immunity against the Obligate Intracellular Bacterial Pathogen Rickettsia australis Requires a Functional Complement System. |
Volume: |
86 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pozdnyakova O |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Impaired antibody response to group B streptococcal type III capsular polysaccharide in C3- and complement receptor 2-deficient mice. |
Volume: |
170 |
Issue: |
1 |
Pages: |
84-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Einav S |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Complement C4 is protective for lupus disease independent of C3. |
Volume: |
168 |
Issue: |
3 |
Pages: |
1036-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto T |
Year: |
2016 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion. |
Volume: |
310 |
Issue: |
8 |
Pages: |
H1003-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu M |
Year: |
2012 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
A novel role of complement in retinal degeneration. |
Volume: |
53 |
Issue: |
12 |
Pages: |
7684-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li HY |
Year: |
2022 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation. |
Volume: |
13 |
Issue: |
1 |
Pages: |
289-307 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2020 |
Journal: |
Nature |
Title: |
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. |
Volume: |
588 |
Issue: |
7838 |
Pages: |
459-465 |
|
•
•
•
•
•
|
Publication |
First Author: |
Green RS |
Year: |
2007 |
Journal: |
Immunity |
Title: |
Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis. |
Volume: |
27 |
Issue: |
2 |
Pages: |
308-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zabel MD |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis. |
Volume: |
179 |
Issue: |
9 |
Pages: |
6144-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Møller-Kristensen M |
Year: |
2007 |
Journal: |
J Invest Dermatol |
Title: |
Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice. |
Volume: |
127 |
Issue: |
6 |
Pages: |
1524-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng Z |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3. |
Volume: |
12 |
Issue: |
1 |
Pages: |
6202 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ueda Y |
Year: |
2017 |
Journal: |
Blood |
Title: |
Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation. |
Volume: |
129 |
Issue: |
9 |
Pages: |
1184-1196 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rozanov DV |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice. |
Volume: |
66 |
Issue: |
12 |
Pages: |
6258-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zelko I |
Year: |
1998 |
Journal: |
Arch Biochem Biophys |
Title: |
Molecular cloning and characterization of a novel nuclear protein kinase in mice. |
Volume: |
352 |
Issue: |
1 |
Pages: |
31-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borkowska S |
Year: |
2014 |
Journal: |
Leukemia |
Title: |
Novel evidence that crosstalk between the complement, coagulation and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs). |
Volume: |
28 |
Issue: |
11 |
Pages: |
2148-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yan J |
Year: |
1999 |
Journal: |
J Immunol |
Title: |
Beta-glucan, a "specific" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18). |
Volume: |
163 |
Issue: |
6 |
Pages: |
3045-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Holers VM |
Year: |
1992 |
Journal: |
Immunol Today |
Title: |
The evolution of mouse and human complement C3-binding proteins: divergence of form but conservation of function. |
Volume: |
13 |
Issue: |
6 |
Pages: |
231-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pritchard MT |
Year: |
2007 |
Journal: |
Gastroenterology |
Title: |
Differential contributions of C3, C5, and decay-accelerating factor to ethanol-induced fatty liver in mice. |
Volume: |
132 |
Issue: |
3 |
Pages: |
1117-1126 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li RG |
Year: |
2024 |
Journal: |
Nat Cardiovasc Res |
Title: |
YAP induces a neonatal-like pro-renewal niche in the adult heart. |
Volume: |
3 |
Issue: |
3 |
Pages: |
283-300 |
|
•
•
•
•
•
|
Publication |
First Author: |
Angeletti A |
Year: |
2020 |
Journal: |
J Exp Med |
Title: |
Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis. |
Volume: |
217 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kulik L |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus. |
Volume: |
203 |
Issue: |
12 |
Pages: |
3136-3147 |
|
•
•
•
•
•
|
Publication |
First Author: |
Donius LR |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Optimal germinal center B cell activation and T-dependent antibody responses require expression of the mouse complement receptor Cr1. |
Volume: |
191 |
Issue: |
1 |
Pages: |
434-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baumann U |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung. |
Volume: |
167 |
Issue: |
2 |
Pages: |
1022-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seifert L |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
The classical pathway triggers pathogenic complement activation in membranous nephropathy. |
Volume: |
14 |
Issue: |
1 |
Pages: |
473 |
|
•
•
•
•
•
|
Component |
Name: |
Complement C3 beta chain |
|
•
•
•
•
•
|
Component |
Name: |
Complement C3 alpha chain |
|
•
•
•
•
•
|
HT Sample |
Organism Name: |
mouse, laboratory |
Sex: |
Male |
Age: |
postnatal week 10-24 |
Stage: |
28 |
Structure . Name: |
brain |
Notes: |
wild type voxel C3 |
Curation Status: |
Curated |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang T |
Year: |
1997 |
Journal: |
J Exp Med |
Title: |
A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis. |
Volume: |
186 |
Issue: |
11 |
Pages: |
1853-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang YS |
Year: |
2006 |
Journal: |
Cell |
Title: |
A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q. |
Volume: |
125 |
Issue: |
1 |
Pages: |
47-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gnanaguru G |
Year: |
2023 |
Journal: |
Development |
Title: |
Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis. |
Volume: |
150 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Peterson SL |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Retinal Ganglion Cell Axon Regeneration Requires Complement and Myeloid Cell Activity within the Optic Nerve. |
Volume: |
41 |
Issue: |
41 |
Pages: |
8508-8531 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moll T |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
A critical role for Fc gamma RIIB in the induction of rheumatoid factors. |
Volume: |
173 |
Issue: |
7 |
Pages: |
4724-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prodeus AP |
Year: |
1997 |
Journal: |
Nature |
Title: |
Impaired mast cell-dependent natural immunity in complement C3-deficient mice. |
Volume: |
390 |
Issue: |
6656 |
Pages: |
172-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Banda NK |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway. |
Volume: |
179 |
Issue: |
6 |
Pages: |
4101-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Escamilla-Rivera V |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice. |
Volume: |
12 |
|
Pages: |
704072 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou W |
Year: |
2006 |
Journal: |
Blood |
Title: |
Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. |
Volume: |
107 |
Issue: |
6 |
Pages: |
2461-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giacomin PR |
Year: |
2008 |
Journal: |
Mol Immunol |
Title: |
The role of complement in innate, adaptive and eosinophil-dependent immunity to the nematode Nippostrongylus brasiliensis. |
Volume: |
45 |
Issue: |
2 |
Pages: |
446-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu G |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CRIg plays an essential role in intravascular clearance of bloodborne parasites by interacting with complement. |
Volume: |
116 |
Issue: |
48 |
Pages: |
24214-24220 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa M |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
CD19 can regulate B lymphocyte signal transduction independent of complement activation. |
Volume: |
167 |
Issue: |
6 |
Pages: |
3190-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang C |
Year: |
2011 |
Journal: |
Blood |
Title: |
Decay-accelerating factor regulates T-cell immunity in the context of inflammation by influencing costimulatory molecule expression on antigen-presenting cells. |
Volume: |
118 |
Issue: |
4 |
Pages: |
1008-14 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Soochul Park |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1322 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beaver M |
Year: |
2024 |
Journal: |
Front Immunol |
Title: |
C1q is elevated during chronic Staphylococcus epidermidis central nervous system catheter infection. |
Volume: |
15 |
|
Pages: |
1342467 |
|
•
•
•
•
•
|
Publication |
First Author: |
Graham LC |
Year: |
2020 |
Journal: |
eNeuro |
Title: |
Deficiency of Complement Component C1Q Prevents Cerebrovascular Damage and White Matter Loss in a Mouse Model of Chronic Obesity. |
Volume: |
7 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fang C |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Complement-dependent enhancement of CD8+ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice. |
Volume: |
179 |
Issue: |
5 |
Pages: |
3178-86 |
|
•
•
•
•
•
|