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Search results 201 to 300 out of 405 for C4a

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10877
Specimen Label: GUDMAP:10877
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2894021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10878
Specimen Label: GUDMAP:10878
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2914321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10877
Note: possible expression which may be background
Specimen Label: GUDMAP:10877
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797321
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10877
Specimen Label: GUDMAP:10877
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2892421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10878
Note: possible expression but most likely to be background
Specimen Label: GUDMAP:10878
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6189893
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - C4b
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6189893
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - C4b
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6189893
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - C4b
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6189893
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - C4b
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189893
Age: postnatal day 4
Specimen Label: Table S2 - P4 - C4b
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189893
Age: postnatal day 14
Specimen Label: Table S2 - P14 - C4b
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6168808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189893
Age: postnatal day 28
Specimen Label: Table S2 - P28 - C4b
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7451095
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7451210
Age: postnatal
Image: S14a
Specimen Label: S14a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10878
Specimen Label: GUDMAP:10878
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4846031
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:3046021
Stage: TS21
Assay Id: MGI:5540842
Age: embryonic day 13.5
Image: GUDMAP:10877
Specimen Label: GUDMAP:10877
Detected: false
Specimen Num: 1
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Publication
- | J:14339
 
First Author: WHO-IUIS Nomenclature Sub-Committee
Year: 1993
Journal: Eur J Immunogenet
Title: Revised nomenclature for human complement component C4.
Volume: 20
Pages: 301-305
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Publication
8373374 | J:14523
 
First Author: Cheng J
Year: 1993
Journal: Biochem J
Title: cDNA cloning and characterization of the protein encoded by RD, a gene located in the class III region of the human major histocompatibility complex.
Volume: 294 ( Pt 2)
Pages: 589-93
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Publication
11341920 | -
First Author: Laich A
Year: 2001
Journal: Biochim Biophys Acta
Title: Complement C4bC2 complex formation: an investigation by surface plasmon resonance.
Volume: 1544
Issue: 1-2
Pages: 96-112
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Publication
9642242 | -
First Author: Rawal N
Year: 1998
Journal: J Biol Chem
Title: C5 convertase of the alternative pathway of complement. Kinetic analysis of the free and surface-bound forms of the enzyme.
Volume: 273
Issue: 27
Pages: 16828-35
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Publication
3546307 | -
First Author: Kam CM
Year: 1987
Journal: J Biol Chem
Title: Human complement proteins D, C2, and B. Active site mapping with peptide thioester substrates.
Volume: 262
Issue: 8
Pages: 3444-51
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
3081348 | -
First Author: Gennaro R
Year: 1986
Journal: Eur J Biochem
Title: C5a fragment of bovine complement. Purification, bioassays, amino-acid sequence and other structural studies.
Volume: 155
Issue: 1
Pages: 77-86
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Publication
1431125 | -
First Author: Fritzinger DC
Year: 1992
Journal: J Immunol
Title: Primary structure of cobra complement component C3.
Volume: 149
Issue: 11
Pages: 3554-62
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Protein Domain
IPR018081 | Anaphylatoxin_comp_syst
Type: Homologous_superfamily
Description: Complement components C3, C4 and C5 are large glycoproteins that have important functions in the immune response and host defence []. They have a wide variety of biological activities and are proteolytically activated by cleavage at a specific site, forming a- and b-fragments []. A-fragments form distinct structural domains of approximately 76 amino acids, coded for by a single exon within the complement protein gene. The C3a, C4a and C5a components are referred to as anaphylatoxins [, ]: they cause smooth muscle contraction, histamine release from mast cells, and enhanced vascular permeability []. They also mediate chemotaxis, inflammation, and generation of cytotoxic oxygen radicals []. The proteins are highly hydrophilic, with a mainly α-helical structure held together by 3 disulphide bridges [].
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Publication
8245130 | J:16328
First Author: Pan TC
Year: 1993
Journal: J Cell Biol
Title: Structure and expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding.
Volume: 123
Issue: 5
Pages: 1269-77
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Publication
2269669 | -
First Author: Argraves WS
Year: 1990
Journal: J Cell Biol
Title: Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure.
Volume: 111
Issue: 6 Pt 2
Pages: 3155-64
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Protein Domain
IPR000020 | Anaphylatoxin/fibulin
Type: Domain
Description: This entry represents C3a, C4a and C5a anaphylatoxins, which are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to a three-fold repeat in fibulins.Complement components C3, C4 and C5 are large glycoproteins that have important functions in the immune response and host defence []. They have a wide variety of biological activities and are proteolytically activated by cleavage at a specific site, forming a- and b-fragments []. A-fragments form distinct structural domains of approximately 76 amino acids, coded for by a single exon within the complement protein gene. The C3a, C4a and C5a components are referred to as anaphylatoxins [, ]: they cause smooth muscle contraction, histamine release from mast cells, and enhanced vascular permeability []. They also mediate chemotaxis, inflammation, and generation of cytotoxic oxygen radicals []. The proteins are highly hydrophilic, with a mainly α-helical structure held together by 3 disulphide bridges [].Fibulins are secreted glycoproteins that become incorporated into a fibrillar extracellular matrix when expressed by cultured cells or added exogenously to cell monolayers [, ]. The five known members of the family share an elongated structure and many calcium-binding sites, owing to the presence of tandem arrays of epidermal growth factor-like domains. They have overlapping binding sites for several basement-membrane proteins, tropoelastin, fibrillin, fibronectin and proteoglycans, and they participate in diverse supramolecular structures. The amino-terminal domain I of fibulin consists of three anaphylatoxin-like (AT) modules, each approximately 40 residues long and containing four or six cysteines. The structure of an AT module was determined for the complement-derived anaphylatoxin C3a, and was found to be a compact α-helical fold that is stabilised by three disulphide bridges in the pattern Cys1-4, Cys2-5 and Cys3-6 (where Cys is cysteine). The bulk of the remaining portion of the fibulin molecule is a series of nine EGF-like repeats [].
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Protein
V9H0U1
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: true
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Publication
9164946 | J:40631
First Author: Tornetta MA
Year: 1997
Journal: J Immunol
Title: The mouse anaphylatoxin C3a receptor: molecular cloning, genomic organization, and functional expression.
Volume: 158
Issue: 11
Pages: 5277-82
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Publication
9382922 | J:44712
First Author: Hsu MH
Year: 1997
Journal: Immunogenetics
Title: Cloning and functional characterization of the mouse C3a anaphylatoxin receptor gene.
Volume: 47
Issue: 1
Pages: 64-72
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Publication
16148115 | J:116731
First Author: Honczarenko M
Year: 2005
Journal: J Immunol
Title: Complement C3a enhances CXCL12 (SDF-1)-mediated chemotaxis of bone marrow hematopoietic cells independently of C3a receptor.
Volume: 175
Issue: 6
Pages: 3698-706
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Publication
14975236 | J:89757
First Author: Mao C
Year: 2004
Journal: Immunity
Title: T cell-independent somatic hypermutation in murine B cells with an immature phenotype.
Volume: 20
Issue: 2
Pages: 133-44
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Publication
17024247 | J:114506
First Author: Nelson KC
Year: 2006
Journal: J Clin Invest
Title: Role of different pathways of the complement cascade in experimental bullous pemphigoid.
Volume: 116
Issue: 11
Pages: 2892-900
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Publication
16849503 | J:138361
First Author: Banda NK
Year: 2006
Journal: J Immunol
Title: Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.
Volume: 177
Issue: 3
Pages: 1904-12
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Publication
16702544 | J:110220
First Author: Taube C
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
Volume: 103
Issue: 21
Pages: 8084-9
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Publication
11857338 | J:115361
First Author: Solomon S
Year: 2002
Journal: Eur J Immunol
Title: Transmission of antibody-induced arthritis is independent of complement component 4 (C4) and the complement receptors 1 and 2 (CD21/35).
Volume: 32
Issue: 3
Pages: 644-51
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Publication
30926239 | J:282445
First Author: Bottermann M
Year: 2019
Journal: Cell Host Microbe
Title: Complement C4 Prevents Viral Infection through Capsid Inactivation.
Volume: 25
Issue: 4
Pages: 617-629.e7
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Publication
24868011 | J:327063
First Author: Asgari E
Year: 2014
Journal: FASEB J
Title: Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4.
Volume: 28
Issue: 9
Pages: 3996-4003
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Publication
39310747 | J:354245
First Author: Fournier LA
Year: 2024
Journal: iScience
Title: Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction.
Volume: 27
Issue: 9
Pages: 110800
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Publication
910130 | J:5879
First Author: Meo T
Year: 1977
Journal: Science
Title: Glyoxalase I polymorphism in the mouse: a new genetic marker linked to H-2.
Volume: 198
Issue: 4314
Pages: 311-3
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Publication
6885117 | J:7167
First Author: Natsuume-Sakai S
Year: 1983
Journal: Immunogenetics
Title: Structural polymorphism of murine factor B controlled by a locus closely linked to the H-2 complex and demonstration of multiple alleles.
Volume: 18
Issue: 2
Pages: 117-24
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Publication
3902621 | J:8065
 
First Author: Tosi M
Year: 1985
Journal: Immunol Rev
Title: Duplications of complement and non-complement genes of the H-2S region: evolutionary aspects of the C4 isotypes and molecular analysis of their expression variants.
Volume: 87
Pages: 151-83
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Publication
19302245 | J:320300
First Author: Gullstrand B
Year: 2009
Journal: Clin Exp Immunol
Title: Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells.
Volume: 156
Issue: 2
Pages: 303-11
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Publication
19783065 | J:320301
First Author: Wallis R
Year: 2010
Journal: Immunobiology
Title: Paths reunited: Initiation of the classical and lectin pathways of complement activation.
Volume: 215
Issue: 1
Pages: 1-11
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Protein
Q14BD9
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q505K6
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
A2AS37
Organism: Mus musculus/domesticus
Length: 356  
Fragment?: false
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Protein
A0A2I3BQE1
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
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Protein
Q8BWS8
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
A0A2I3BRQ1
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
Q8BWN9
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein Domain
IPR001840 | Anaphylatoxn_comp_syst_dom
Type: Domain
Description: Complement components C3, C4 and C5 are large glycoproteins that have important functions in the immune response and host defence []. They have a wide variety of biological activities and are proteolytically activated by cleavage at a specific site, forming a- and b-fragments []. A-fragments form distinct structural domains of approximately 76 amino acids, coded for by a single exon within the complement protein gene. The C3a, C4a and C5a components are referred to as anaphylatoxins [, ]: they cause smooth muscle contraction, histamine release from mast cells, and enhanced vascular permeability []; they also mediate chemotaxis, inflammation, and generation of cytotoxic oxygen radicals []. The proteins are highly hydrophilic, with a mainly α-helical structure held together by 3 disulphide bridges [].Some of the proteins in this group are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane. Most of these markers are proteins, but some are carbohydrates attached to lipids or proteins [Reid M.E., Lomas-Francis C. The Blood Group Antigen FactsBook Academic Press, London / San Diego, (1997)]. Complement C4 belongs to the Chido/Rodgers blood group system and is associated with Ch1 to Ch6, WH, Rg1 and Rg2 antigens.
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Publication
7835888 | J:20813
First Author: Cazzaniga G
Year: 1994
Journal: Genomics
Title: Chromosomal mapping, isolation, and characterization of the mouse xanthine dehydrogenase gene.
Volume: 23
Issue: 2
Pages: 390-402
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Publication
17360462 | J:120063
First Author: Suber F
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Innate response to self-antigen significantly exacerbates burn wound depth.
Volume: 104
Issue: 10
Pages: 3973-7
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Publication
8524789 | J:30152
First Author: Wessels MR
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.
Volume: 92
Issue: 25
Pages: 11490-4
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Publication
11433344 | J:70251
First Author: Springall T
Year: 2001
Journal: Nat Med
Title: Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli.
Volume: 7
Issue: 7
Pages: 801-6
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Publication
21502512 | J:172218
First Author: Schwaeble WJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.
Volume: 108
Issue: 18
Pages: 7523-8
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Publication
14500686 | J:85645
First Author: Tüzün E
Year: 2003
Journal: J Immunol
Title: Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis.
Volume: 171
Issue: 7
Pages: 3847-54
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Publication
11560991 | J:119459
First Author: Manderson AP
Year: 2001
Journal: J Exp Med
Title: Continual low-level activation of the classical complement pathway.
Volume: 194
Issue: 6
Pages: 747-56
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Publication
27088797 | J:234934
First Author: Farrar CA
Year: 2016
Journal: J Clin Invest
Title: Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury.
Volume: 126
Issue: 5
Pages: 1911-25
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Publication
8752901 | J:64282
First Author: Fischer MB
Year: 1996
Journal: J Immunol
Title: Regulation of the B cell response to T-dependent antigens by classical pathway complement.
Volume: 157
Issue: 2
Pages: 549-56
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Publication
25467802 | J:223071
First Author: Cresci GA
Year: 2015
Journal: Mol Immunol
Title: Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CClâ‚„-induced injury.
Volume: 64
Issue: 1
Pages: 9-17
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Publication
9829481 | J:77011
First Author: Hébert MJ
Year: 1998
Journal: Nephrol Dial Transplant
Title: Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria.
Volume: 13
Issue: 11
Pages: 2799-803
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Publication
9218619 | J:78654
First Author: Fischer MB
Year: 1997
Journal: J Immunol
Title: Increased susceptibility to endotoxin shock in complement C3- and C4-deficient mice is corrected by C1 inhibitor replacement.
Volume: 159
Issue: 2
Pages: 976-82
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Publication
9461092 | J:47055
First Author: Quigg RJ
Year: 1998
Journal: Kidney Int
Title: Immune complex glomerulonephritis in C4- and C3-deficient mice.
Volume: 53
Issue: 2
Pages: 320-30
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Publication
681746 | J:6024
First Author: Natsuume-Sakai S
Year: 1978
Journal: J Immunol
Title: Genetic polymorphism of murine C3 controlled by a single co-dominant locus on chromosome 17.
Volume: 121
Issue: 2
Pages: 491-8
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Publication
6088393 | J:7551
First Author: Sackstein R
Year: 1984
Journal: Immunogenetics
Title: Subdivision of the S region of the mouse major histocompatibility complex by identification of genomic polymorphisms of the class III genes.
Volume: 20
Issue: 3
Pages: 321-30
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Publication
8649451 | J:33481
First Author: Ebanks RO
Year: 1996
Journal: Mol Immunol
Title: Mouse complement component C4 is devoid of classical pathway C5 convertase subunit activity.
Volume: 33
Issue: 3
Pages: 297-309
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Publication
2652811 | J:29578
First Author: Cortese Hassett AL
Year: 1989
Journal: Transplant Proc
Title: Mapping and sequencing analysis of the rat MHC.
Volume: 21
Issue: 2
Pages: 3244-6
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Publication
21723612 | J:177216
First Author: Mershon-Shier KL
Year: 2011
Journal: Mol Immunol
Title: In vitro C3 deposition on Cryptococcus capsule occurs via multiple complement activation pathways.
Volume: 48
Issue: 15-16
Pages: 2009-18
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Publication
- | J:13801
 
First Author: Douglas TC
Year: 1979
Journal: Mouse News Lett
Title: Chromosome 17
Volume: 60
Pages: 58
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Publication
3902620 | J:30951
 
First Author: White PC
Year: 1985
Journal: Immunol Rev
Title: Adrenal 21-hydroxylase cytochrome P-450 genes within the MHC class III region.
Volume: 87
Pages: 123-50
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Publication
1618655 | J:1850
First Author: Kawaguchi H
Year: 1992
Journal: Hum Immunol
Title: Organization of C4 and CYP21 loci in gorilla and orangutan.
Volume: 33
Issue: 3
Pages: 153-62
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Protein
Q9QUF7
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
•
•
•
•
•
Protein
Q3TYN1
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: true
•
•
•
•
•
Protein
Q9Z0D8
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
•
•
•
•
•
Protein
Q9Z0J3
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
•
•
•
•
•
Protein
Q9QUF9
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
•
•
•
•
•
Protein
V9GZP9
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
•
•
•
•
•
Protein
Q3TAT4
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: true
•
•
•
•
•
Protein
G3UZS2
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: true
•
•
•
•
•
Protein
Q9QUF8
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: true
•
•
•
•
•
Publication
12778127 | -
First Author: Timpl R
Year: 2003
Journal: Nat Rev Mol Cell Biol
Title: Fibulins: a versatile family of extracellular matrix proteins.
Volume: 4
Issue: 6
Pages: 479-89
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•
•
•
Publication
10946292 | -
First Author: Matsushita M
Year: 2000
Journal: J Immunol
Title: Proteolytic activities of two types of mannose-binding lectin-associated serine protease.
Volume: 165
Issue: 5
Pages: 2637-42
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•
•
•
•
Publication
6906228 | J:320299
First Author: Kerr MA
Year: 1980
Journal: Biochem J
Title: The human complement system: assembly of the classical pathway C3 convertase.
Volume: 189
Issue: 1
Pages: 173-81
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•
•
•
•
Publication
21393236 | J:172081
First Author: Heimbach L
Year: 2011
Journal: J Biol Chem
Title: The C5a receptor on mast cells is critical for the autoimmune skin-blistering disease bullous pemphigoid.
Volume: 286
Issue: 17
Pages: 15003-9
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•
•
•
•
Publication
11067882 | J:111811
First Author: Chen Z
Year: 2000
Journal: J Exp Med
Title: Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
Volume: 192
Issue: 9
Pages: 1339-52
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•
•
•
•
Publication
19001138 | J:141398
First Author: Gupta VA
Year: 2008
Journal: J Exp Med
Title: B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency.
Volume: 205
Issue: 12
Pages: 2755-61
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•
•
•
•
Publication
11801636 | J:127292
First Author: Einav S
Year: 2002
Journal: J Immunol
Title: Complement C4 is protective for lupus disease independent of C3.
Volume: 168
Issue: 3
Pages: 1036-41
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•
•
•
•
Publication
20810984 | J:164313
First Author: Renner B
Year: 2010
Journal: J Immunol
Title: B cell subsets contribute to renal injury and renal protection after ischemia/reperfusion.
Volume: 185
Issue: 7
Pages: 4393-400
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•
•
•
Publication
12421924 | J:80067
First Author: Gadjeva M
Year: 2002
Journal: J Immunol
Title: Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice.
Volume: 169
Issue: 10
Pages: 5489-95
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•
•
•
•
Publication
10066708 | J:78613
First Author: Williams JP
Year: 1999
Journal: J Appl Physiol (1985)
Title: Intestinal reperfusion injury is mediated by IgM and complement.
Volume: 86
Issue: 3
Pages: 938-42
•
•
•
•
•
Publication
16304047 | J:129369
First Author: Zhou W
Year: 2006
Journal: Blood
Title: Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells.
Volume: 107
Issue: 6
Pages: 2461-9
•
•
•
•
•
Publication
15102802 | J:89480
First Author: Mueller-Ortiz SL
Year: 2004
Journal: Infect Immun
Title: The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia.
Volume: 72
Issue: 5
Pages: 2899-906
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•
•
•
•
Publication
22689574 | J:225116
First Author: Ramos TN
Year: 2012
Journal: J Biol Chem
Title: The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.
Volume: 287
Issue: 29
Pages: 24734-8
•
•
•
•
•
Publication
30301856 | J:286325
 
First Author: Gralinski LE
Year: 2018
Journal: mBio
Title: Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis.
Volume: 9
Issue: 5
•
•
•
•
•
Publication
18452991 | J:136225
First Author: Clark A
Year: 2008
Journal: Mol Immunol
Title: Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.
Volume: 45
Issue: 11
Pages: 3125-32
•
•
•
•
•
Publication
9367154 | J:44240
First Author: Prodeus AP
Year: 1997
Journal: Nature
Title: Impaired mast cell-dependent natural immunity in complement C3-deficient mice.
Volume: 390
Issue: 6656
Pages: 172-5
•
•
•
•
•
Publication
29743491 | J:262983
First Author: Katschke KJ Jr
Year: 2018
Journal: Sci Rep
Title: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.
Volume: 8
Issue: 1
Pages: 7348
•
•
•
•
•
Publication
10934224 | J:63875
First Author: Taylor PR
Year: 2000
Journal: J Exp Med
Title: A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.
Volume: 192
Issue: 3
Pages: 359-66
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•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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