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Search results 201 to 300 out of 358 for C7

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGI_C57BL6J_1928373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018993 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018983 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019062 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018515 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018308 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018021 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802407
Specimen Label: JAX_1802407
Detected: true
Specimen Num: 36
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802404
Specimen Label: JAX_1802404
Detected: true
Specimen Num: 33
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802398
Note: kidney
Specimen Label: JAX_1802398
Detected: true
Specimen Num: 27
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802379
Specimen Label: JAX_1802379
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802412
Specimen Label: JAX_1802412
Detected: true
Specimen Num: 40
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802383
Specimen Label: JAX_1802383
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802403
Specimen Label: JAX_1802403
Detected: true
Specimen Num: 32
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802376
Specimen Label: JAX_1802376
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802409
Specimen Label: JAX_1802409
Detected: true
Specimen Num: 38
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1925228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802391
Specimen Label: JAX_1802391
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802380
Specimen Label: JAX_1802380
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802381
Specimen Label: JAX_1802381
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802406
Specimen Label: JAX_1802406
Detected: true
Specimen Num: 35
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802386
Specimen Label: JAX_1802386
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802405
Specimen Label: JAX_1802405
Detected: true
Specimen Num: 34
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802399
Specimen Label: JAX_1802399
Detected: true
Specimen Num: 28
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1860128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802385
Specimen Label: JAX_1802385
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692243
Age: embryonic day 12.5
Image: JAX_1122905
Specimen Label: JAX_1122905
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692243
Age: embryonic day 12.5
Image: JAX_1122907
Specimen Label: JAX_1122907
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692243
Age: embryonic day 12.5
Image: JAX_1122909
Specimen Label: JAX_1122909
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692243
Age: embryonic day 12.5
Image: JAX_1122911
Specimen Label: JAX_1122911
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802388
Specimen Label: JAX_1802388
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802400
Specimen Label: JAX_1802400
Detected: true
Specimen Num: 29
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802393
Specimen Label: JAX_1802393
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802384
Specimen Label: JAX_1802384
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802410
Specimen Label: JAX_1802410
Detected: true
Specimen Num: 39
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802390
Specimen Label: JAX_1802390
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802378
Specimen Label: JAX_1802378
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802375
Specimen Label: JAX_1802375
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802408
Specimen Label: JAX_1802408
Detected: true
Specimen Num: 37
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802377
Specimen Label: JAX_1802377
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802395
Specimen Label: JAX_1802395
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802394
Specimen Label: JAX_1802394
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802401
Specimen Label: JAX_1802401
Detected: true
Specimen Num: 30
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802387
Specimen Label: JAX_1802387
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802382
Specimen Label: JAX_1802382
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802389
Specimen Label: JAX_1802389
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802392
Specimen Label: JAX_1802392
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802396
Specimen Label: JAX_1802396
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692243
Age: postnatal adult
Image: JAX_1802402
Specimen Label: JAX_1802402
Detected: true
Specimen Num: 31
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Publication
- | J:66349
   
First Author: Ohtsuka K
Year: 1999
Journal: GenBank Submission
Title: Mus musculus mRNA for mDj11, complete cds
Pages: AB028861
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DO Term
DOID:0110295 | autosomal recessive limb-girdle muscular dystrophy type 2U
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Protein
P17515
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: false
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GO Term
GO:0034995 | SC5b-7 complex
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MP Term
MP:0003036 | vertebral transformation
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Publication
15347657 | J:95000
First Author: Squires EJ
Year: 2004
Journal: J Biol Chem
Title: Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver.
Volume: 279
Issue: 47
Pages: 49307-14
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Publication
17139260 | -
First Author: Rodrigues ML
Year: 2006
Journal: EMBO J
Title: X-ray structure of the membrane-bound cytochrome c quinol dehydrogenase NrfH reveals novel haem coordination.
Volume: 25
Issue: 24
Pages: 5951-60
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Protein Domain
IPR029467 | Cyt_c7-like
Type: Domain
Description: This family includes cytochromes c7 and c7-type. In cytochromes c7 all three haems are bis-His coordinated, while in c7-type the last haem is His-Met coordinated []. Desulfuromonas acetoxidans and Geobacter metallireducens cytochrome c7 participate in the anaerobic iron respiration, but Geobacter metallireducens cytochrome c7 hasn't a Fe(III) reductase activity [].This entry also includes cytochrome c nitrite reductase subunit NrfH from Desulfovibrio vulgaris which forms a complex with cytochrome c nitrite reductase NrfA [].
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Allele
C7<Gt1Tigm> | MGI:6164644
Name: complement component 7; gene trap insertion unknown 1, Texas Institute for Genomic Medicine
Allele Type: Gene trapped
Attribute String: Null/knockout
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Protein
D3YXF5
Organism: Mus musculus/domesticus
Length: 845  
Fragment?: false
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Protein Coding Gene
MGI:1352450 | Cxcl10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR040729 | Kazal_3
Type: Domain
Description: This Kazal domain is found in the factor I-like modules (FIMs) region on the C terminus of complement component C7 proteins. Complement component C7 is a subunit of the membrane attack complex (MAC), a fundamental machinery in the mammalian innate immunity. KAZAL domains are common in serine protease inhibitors [].
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Publication
21130881 | -
First Author: Pokkuluri PR
Year: 2011
Journal: J Struct Biol
Title: Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12 nm protein with interacting hemes.
Volume: 174
Issue: 1
Pages: 223-33
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Publication
25542016 | J:225381
First Author: Ohno M
Year: 2014
Journal: PLoS One
Title: The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers.
Volume: 9
Issue: 12
Pages: e115663
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Publication
11161808 | J:67577
First Author: Miyoshi K
Year: 2001
Journal: Genomics
Title: Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.
Volume: 71
Issue: 2
Pages: 150-5
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Publication
8522520 | -
First Author: González-Pastor JE
Year: 1995
Journal: J Bacteriol
Title: Structure and organization of plasmid genes required to produce the translation inhibitor microcin C7.
Volume: 177
Issue: 24
Pages: 7131-40
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Publication
22516613 | -
First Author: Nocek B
Year: 2012
Journal: J Mol Biol
Title: Structural and functional characterization of microcin C resistance peptidase MccF from Bacillus anthracis.
Volume: 420
Issue: 4-5
Pages: 366-83
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Protein Domain
IPR027478 | LdcA_N
Type: Homologous_superfamily
Description: This superfamily represents the N-terminal of muramoyl-tetrapeptide carboxypeptidase, also known as LD-carboxypeptidase A. The enzyme hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. This activity is has a role ine in murein recycling [, ]. Proteins containing this domain also include the microcin c7 self-immunity protein .
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Protein Domain
IPR027461 | Carboxypeptidase_A_C_sf
Type: Homologous_superfamily
Description: This superfamily represents the C-terminal domain of the LD-carboxypeptidase A. Muramoyl-tetrapeptide carboxypeptidase or LD-carboxypeptidase A hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. The function of this activity is in murein recycling [, ]. Proteins containing this domain alsoinclude the microcin c7 self-immunity protein []and microcin immunity protein MccF [].
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Protein Domain
IPR003507 | S66_fam
Type: Family
Description: This entry includes proteins belonging to the MEROPS peptidase family S66, such as muramoyl-tetrapeptide carboxypeptidase and the microcin c7 self-immunity protein . Muramoyl-tetrapeptide carboxypeptidase, also known as LD-carboxypeptidase A, hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. This activity has a role in murein recycling [, ].
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Protein Domain
IPR040921 | Peptidase_S66C
Type: Domain
Description: This entry represents the C-terminal domain of the LD-carboxypeptidase A. Muramoyl-tetrapeptide carboxypeptidase or LD-carboxypeptidase A hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. The function of this activity is in murein recycling [, ]. Proteins containing this domain also include the microcin c7 self-immunity protein []and microcin immunity protein MccF [].
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Publication
10428950 | -
First Author: Templin MF
Year: 1999
Journal: EMBO J
Title: A defect in cell wall recycling triggers autolysis during the stationary growth phase of Escherichia coli.
Volume: 18
Issue: 15
Pages: 4108-17
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Publication
18535144 | -
First Author: Park JT
Year: 2008
Journal: Microbiol Mol Biol Rev
Title: How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan).
Volume: 72
Issue: 2
Pages: 211-27, table of contents
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Publication
11013085 | J:65084
First Author: Pershouse M
Year: 2000
Journal: Genomics
Title: BAC contig from a 3-cM region of mouse chromosome 11 surrounding Brca1.
Volume: 69
Issue: 1
Pages: 139-42
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Publication
16162494 | -
First Author: Korza HJ
Year: 2005
Journal: J Biol Chem
Title: Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.
Volume: 280
Issue: 49
Pages: 40802-12
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Protein Domain
IPR030382 | MeTrfase_TRM5/TYW2
Type: Domain
Description: This entry represents a domain found in the Trm5/Tyw2-type methyltransferase. Trm5 and Tyw2 are S-adenosylmethionine-dependent methyltransferases involved in tRNA methylation []. Wybutosine synthesis is a multienzymatic process that comprises six sequential enzymatic reactions involving five enzymes. The initial step, the formation of m1G-37 (guanosine-37 methylated in the N1 position) in precursor tRNAPhe is catalysed by tRNA wybutosine-synthesising protein 5 (Trm5). Tyw2 catalyses the second step, consisting of the alpha-amino-alpha-carboxypropyl (acp) group being transferred from S-AdoMet to the side chain at the C7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86 [].
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Protein Domain
IPR040449 | Peptidase_S66_N
Type: Domain
Description: This entry includes proteins belonging to the MEROPS peptidase family S66, such as muramoyl-tetrapeptide carboxypeptidase and the microcin c7 self-immunity protein . Muramoyl-tetrapeptide carboxypeptidase, also known as LD-carboxypeptidase A, hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. This activity has a role in murein recycling [, ]. The structure of Pseudomonas aeruginosa LD-carboxypeptidase showed that the enzyme consists of an N-terminal β-sheet and a C-terminal β-barrel domain []. This entry represents the N-terminal domain.
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Publication
2189406 | J:10527
First Author: Ohmori Y
Year: 1990
Journal: Biochem Biophys Res Commun
Title: A macrophage LPS-inducible early gene encodes the murine homologue of IP-10.
Volume: 168
Issue: 3
Pages: 1261-7
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Publication
11237729 | J:74707
First Author: Fischer H
Year: 2001
Journal: Biochem Biophys Res Commun
Title: C7, a novel nucleolar protein, is the mouse homologue of the Drosophila late puff product L82 and an isoform of human OXR1.
Volume: 281
Issue: 3
Pages: 795-803
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Publication
9486801 | J:45780
First Author: Tiret L
Year: 1998
Journal: Development
Title: Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice.
Volume: 125
Issue: 2
Pages: 279-91
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Publication
36257322 | J:340340
First Author: Kollewe A
Year: 2022
Journal: Neuron
Title: Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.
Volume: 110
Issue: 24
Pages: 4162-4175.e7
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Publication
20382657 | -
First Author: de Crécy-Lagard V
Year: 2010
Journal: Mol Biol Evol
Title: Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.
Volume: 27
Issue: 9
Pages: 2062-77
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Protein Domain
IPR003884 | FacI_MAC
Type: Domain
Description: This domain is found in complement component proteins, complement component factor 1 and agrin. Complement components C5b, C6, C7 C8 and C9 are the constituents of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Its assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9. Factor I is responsible for cleaving alpha chains of C4B and C3B in the presence of the cofactors C4-binding protein and factor H respectively. Agrin is a component of the basal lamina that causes the aggregation of acetylcholine receptors and acetylcholine-esterase on the surface of muscle fibres of the neuromuscular junction.
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Publication
11147971 | J:67228
First Author: Ohtsuka K
Year: 2000
Journal: Cell Stress Chaperones
Title: Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.
Volume: 5
Issue: 2
Pages: 98-112
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Publication
9832122 | J:51042
First Author: Pang L
Year: 1998
Journal: J Neurochem
Title: The mouse GalR2 galanin receptor: genomic organization, cDNA cloning, and functional characterization.
Volume: 71
Issue: 6
Pages: 2252-9
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Publication
22402829 | J:345439
First Author: Krug SM
Year: 2012
Journal: Cell Mol Life Sci
Title: Claudin-17 forms tight junction channels with distinct anion selectivity.
Volume: 69
Issue: 16
Pages: 2765-78
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Publication
23291558 | J:206907
First Author: Xu CX
Year: 2013
Journal: Toxicol Sci
Title: Aryl hydrocarbon receptor activation attenuates Per1 gene induction and influences circadian clock resetting.
Volume: 132
Issue: 2
Pages: 368-78
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Publication
35351885 | J:327495
First Author: Yang N
Year: 2022
Journal: Nat Commun
Title: Lung type II alveolar epithelial cells collaborate with CCR2+ inflammatory monocytes in host defense against poxvirus infection.
Volume: 13
Issue: 1
Pages: 1671
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Publication
25640200 | J:224017
First Author: Liao Y
Year: 2015
Journal: Stem Cells
Title: Rescue of the mucocutaneous manifestations by human cord blood derived nonhematopoietic stem cells in a mouse model of recessive dystrophic epidermolysis bullosa.
Volume: 33
Issue: 6
Pages: 1807-17
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Publication
26203639 | J:227734
First Author: Hou Y
Year: 2015
Journal: J Invest Dermatol
Title: Intravenously Administered Recombinant Human Type VII Collagen Derived from Chinese Hamster Ovary Cells Reverses the Disease Phenotype in Recessive Dystrophic Epidermolysis Bullosa Mice.
Volume: 135
Issue: 12
Pages: 3060-3067
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Publication
33613100 | J:304881
First Author: Zhang R
Year: 2021
Journal: Int J Biol Sci
Title: Spreading of pathological TDP-43 along corticospinal tract axons induces ALS-like phenotypes in Atg5+/- mice.
Volume: 17
Issue: 2
Pages: 390-401
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Publication
27187787 | J:249220
First Author: Melhuish TA
Year: 2016
Journal: PLoS One
Title: Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.
Volume: 11
Issue: 5
Pages: e0155837
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Publication
- | J:122430
 
First Author: Orren A
Year: 1989
Journal: VIth Complement Genetics Workshop and Conference
Title: C6 polymorphism and C6 deficiency in site strains of the mutation prone Peru-Coppock mice
Volume: 6
Pages: 295-296 (Abstr.)
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Publication
20460438 | J:354395
First Author: Rosenthal R
Year: 2010
Journal: J Cell Sci
Title: Claudin-2, a component of the tight junction, forms a paracellular water channel.
Volume: 123
Issue: Pt 11
Pages: 1913-21
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Publication
10878384 | J:63178
First Author: Agah A
Year: 2000
Journal: J Immunol
Title: Isolation, characterization, and cloning of porcine complement component C7.
Volume: 165
Issue: 2
Pages: 1059-65
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Publication
7927890 | J:20942
First Author: Nishimori H
Year: 1994
Journal: Int J Cancer
Title: Frequent deletion in chromosome 4 and duplication of chromosome 15 in liver epithelial cells derived from long-term culture of C3H mouse hepatocytes.
Volume: 59
Issue: 1
Pages: 108-13
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Publication
9356216 | J:43997
First Author: Gieseg MA
Year: 1997
Journal: Gen Comp Endocrinol
Title: Elephantfish proinsulin possesses a monobasic processing site.
Volume: 108
Issue: 2
Pages: 199-208
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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