Type |
Details |
Score |
Publication |
First Author: |
Yu W |
Year: |
2019 |
Journal: |
Lab Invest |
Title: |
Lens-specific conditional knockout of Msx2 in mice leads to ocular anterior segment dysgenesis via activation of a calcium signaling pathway. |
Volume: |
99 |
Issue: |
11 |
Pages: |
1714-1727 |
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•
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Publication |
First Author: |
Sheng X |
Year: |
2022 |
Journal: |
EBioMedicine |
Title: |
The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals. |
Volume: |
75 |
|
Pages: |
103790 |
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•
•
•
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Publication |
First Author: |
Takano J |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
Vital role of the calpain-calpastatin system for placental-integrity-dependent embryonic survival. |
Volume: |
31 |
Issue: |
19 |
Pages: |
4097-106 |
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•
•
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Publication |
First Author: |
Nakagawa O |
Year: |
2005 |
Journal: |
Genes Dev |
Title: |
Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2. |
Volume: |
19 |
Issue: |
17 |
Pages: |
2066-77 |
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•
•
•
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Publication |
First Author: |
Kumar V |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. |
Volume: |
211 |
Issue: |
5 |
Pages: |
1057-75 |
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•
•
•
•
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Publication |
First Author: |
Alldred MJ |
Year: |
2015 |
Journal: |
J Comp Neurol |
Title: |
Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice. |
Volume: |
523 |
Issue: |
1 |
Pages: |
61-74 |
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•
•
•
•
•
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Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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•
•
•
•
•
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Publication |
First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
Year: |
2023 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
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•
•
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Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
|
Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
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•
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•
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Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
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•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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•
•
•
•
•
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
•
•
•
•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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|
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•
•
•
•
•
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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•
•
•
•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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|
|
•
•
•
•
•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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|
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•
•
•
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•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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|
|
•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
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•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
UniProt Feature |
Begin: |
375 |
Description: |
Cleavage; by CAPN1 |
Type: |
site |
End: |
376 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
388 |
Description: |
Cleavage; by CAPN1 |
Type: |
site |
End: |
389 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
410 |
Description: |
Cleavage; by CAPN1 and CAPN3 |
Type: |
site |
End: |
411 |
|
•
•
•
•
•
|
Allele |
Name: |
calpain 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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•
•
•
•
•
|
DO Term |
|
•
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Franco S |
Year: |
2004 |
Journal: |
Exp Cell Res |
Title: |
Isoform specific function of calpain 2 in regulating membrane protrusion. |
Volume: |
299 |
Issue: |
1 |
Pages: |
179-87 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Calpain-2 (CAPN2, also known as m-calpain) belongs to the calpain family, which consists of a group of Ca2+ dependent cysteine proteases that regulate functions of substrates by proteolysis [, ]. The most abundant members of the calpain familiy are CAPN1 and CAPN2. They form heterodimers, which are regulated by a small regulatory subunit (28kDa) encoded by the gene Capn4 []. CAPN2 is required for proteolysis of cytoskeletal and focal adhesion proteins, such as FAK, paxillin, spectrin, and talin []. The cleavage of the cytoskeletal protein talin-1 (TLN1) by CAPN2 is critical for the disassembly of focal adhesions []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan Y |
Year: |
2006 |
Journal: |
Genesis |
Title: |
Conditional disruption of ubiquitous calpains in the mouse. |
Volume: |
44 |
Issue: |
6 |
Pages: |
297-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan Y |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis. |
Volume: |
281 |
Issue: |
23 |
Pages: |
16016-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ojima K |
Year: |
2020 |
Journal: |
Biol Open |
Title: |
Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells. |
Volume: |
9 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tanner JJ |
Year: |
2016 |
Journal: |
Biochemistry |
Title: |
EF5 Is the High-Affinity Mg(2+) Site in ALG-2. |
Volume: |
55 |
Issue: |
36 |
Pages: |
5128-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cataldo F |
Year: |
2013 |
Journal: |
Mol Cell Biol |
Title: |
CAPNS1 regulates USP1 stability and maintenance of genome integrity. |
Volume: |
33 |
Issue: |
12 |
Pages: |
2485-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miller JA |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Distinct Changes in Calpain and Calpastatin during PNS Myelination and Demyelination in Rodent Models. |
Volume: |
23 |
Issue: |
23 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Piper AK |
Year: |
2020 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Loss of calpains-1 and -2 prevents repair of plasma membrane scrape injuries, but not small pores, and induces a severe muscular dystrophy. |
Volume: |
318 |
Issue: |
6 |
Pages: |
C1226-C1237 |
|
•
•
•
•
•
|
Publication |
First Author: |
Menon S |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Galectin-3 secretion and tyrosine phosphorylation is dependent on the calpain small subunit, Calpain 4. |
Volume: |
410 |
Issue: |
1 |
Pages: |
91-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
RodrÃguez-Fernández L |
Year: |
2016 |
Journal: |
Biochem J |
Title: |
Isoform-specific function of calpains in cell adhesion disruption: studies in postlactational mammary gland and breast cancer. |
Volume: |
473 |
Issue: |
18 |
Pages: |
2893-909 |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
35
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
530
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
421
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
700
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
700
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
700
 |
Fragment?: |
false |
|
•
•
•
•
•
|