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Search results 201 to 300 out of 485 for Casp4

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5001258
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2776423
Stage: TS23
Assay Id: MGI:5541814
Age: embryonic day 15.5
Image: GUDMAP:13792
Specimen Label: GUDMAP:13792
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001258
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541814
Age: embryonic day 15.5
Image: GUDMAP:13792
Specimen Label: GUDMAP:13792
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001258
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2772123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541814
Age: embryonic day 15.5
Image: GUDMAP:13792
Specimen Label: GUDMAP:13792
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001258
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2801123
Stage: TS23
Assay Id: MGI:5541814
Age: embryonic day 15.5
Image: GUDMAP:13792
Specimen Label: GUDMAP:13792
Detected: false
Specimen Num: 1
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Publication
16670335 | J:131780
First Author: Endo M
Year: 2006
Journal: J Immunol
Title: C/EBP homologous protein (CHOP) is crucial for the induction of caspase-11 and the pathogenesis of lipopolysaccharide-induced inflammation.
Volume: 176
Issue: 10
Pages: 6245-53
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Publication
29653983 | J:325839
First Author: Zeng Q
Year: 2018
Journal: Cancer Immunol Res
Title: Caspase-1 from Human Myeloid-Derived Suppressor Cells Can Promote T Cell-Independent Tumor Proliferation.
Volume: 6
Issue: 5
Pages: 566-577
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Publication
32346861 | J:350633
First Author: Tang Y
Year: 2020
Journal: Br J Pharmacol
Title: Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility.
Volume: 177
Issue: 15
Pages: 3519-3534
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Publication
33882312 | J:314759
First Author: Kumari P
Year: 2021
Journal: Cell Rep
Title: Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense.
Volume: 35
Issue: 3
Pages: 109012
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Publication
24850431 | J:296300
First Author: Demon D
Year: 2014
Journal: Mucosal Immunol
Title: Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis.
Volume: 7
Issue: 6
Pages: 1480-91
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Publication
28345580 | J:263294
 
First Author: Man SM
Year: 2017
Journal: Sci Rep
Title: Differential roles of caspase-1 and caspase-11 in infection and inflammation.
Volume: 7
Pages: 45126
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Publication
32641037 | J:292497
First Author: Sachdev U
Year: 2020
Journal: Mol Med
Title: Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine.
Volume: 26
Issue: 1
Pages: 69
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Publication
22658523 | J:187307
First Author: Akhter A
Year: 2012
Journal: Immunity
Title: Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.
Volume: 37
Issue: 1
Pages: 35-47
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Publication
32111733 | J:287627
First Author: Wang Z
Year: 2020
Journal: J Immunol
Title: Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo.
Volume: 204
Issue: 7
Pages: 1929-1942
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Publication
31492850 | J:279354
First Author: Lu Y
Year: 2019
Journal: Nat Commun
Title: Caspase-11 signaling enhances graft-versus-host disease.
Volume: 10
Issue: 1
Pages: 4044
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Publication
33441602 | J:300439
First Author: Estfanous S
Year: 2021
Journal: Sci Rep
Title: Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo.
Volume: 11
Issue: 1
Pages: 855
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Publication
36185365 | J:351523
First Author: Liu Y
Year: 2022
Journal: iScience
Title: Mixed lineage kinase-like protein protects against Clostridium perfringens infection by enhancing NLRP3 inflammasome-extracellular traps axis.
Volume: 25
Issue: 10
Pages: 105121
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Publication
32401674 | J:298166
First Author: Perlee D
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Caspase-11 contributes to pulmonary host defense against Klebsiella pneumoniae and local activation of coagulation.
Volume: 319
Issue: 1
Pages: L105-L114
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Publication
29472103 | J:270123
 
First Author: Yi YS
Year: 2018
Journal: EBioMedicine
Title: p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice.
Volume: 29
Pages: 78-91
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Publication
34676213 | J:313678
 
First Author: Suarez-Berumen K
Year: 2021
Journal: Front Cell Dev Biol
Title: Pannexin 1 Regulates Skeletal Muscle Regeneration by Promoting Bleb-Based Myoblast Migration and Fusion Through a Novel Lipid Based Signaling Mechanism.
Volume: 9
Pages: 736813
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Publication
29643381 | J:278097
First Author: Dvoriantchikova G
Year: 2018
Journal: Sci Rep
Title: Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells.
Volume: 8
Issue: 1
Pages: 5797
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Publication
28614717 | J:251828
First Author: Błażejewski AJ
Year: 2017
Journal: Cell Rep
Title: Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation.
Volume: 19
Issue: 11
Pages: 2319-2330
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Publication
28990935 | J:252593
First Author: Cheng KT
Year: 2017
Journal: J Clin Invest
Title: Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.
Volume: 127
Issue: 11
Pages: 4124-4135
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Publication
33110056 | J:298974
First Author: Wiernicki B
Year: 2020
Journal: Cell Death Dis
Title: Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis.
Volume: 11
Issue: 10
Pages: 922
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Publication
30589883 | J:333171
First Author: Cerqueira DM
Year: 2018
Journal: PLoS Pathog
Title: Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.
Volume: 14
Issue: 12
Pages: e1007519
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Publication
29414788 | J:264197
First Author: Ramirez MLG
Year: 2018
Journal: J Biol Chem
Title: Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1.
Volume: 293
Issue: 18
Pages: 7058-7067
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Publication
30571969 | J:294379
First Author: Aira LE
Year: 2019
Journal: J Invest Dermatol
Title: Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice.
Volume: 139
Issue: 6
Pages: 1306-1317
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Publication
31998283 | J:297750
 
First Author: de Sant'Ana LP
Year: 2019
Journal: Front Immunol
Title: Absence of the Caspases 1/11 Modulates Liver Global Lipid Profile and Gut Microbiota in High-Fat-Diet-Induced Obese Mice.
Volume: 10
Pages: 2926
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Publication
38522070 | J:349723
First Author: Wright SS
Year: 2024
Journal: Cell Rep
Title: A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis.
Volume: 43
Issue: 4
Pages: 114004
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Publication
9491891 | J:46167
First Author: Wang S
Year: 1998
Journal: Cell
Title: Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.
Volume: 92
Issue: 4
Pages: 501-9
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Publication
33055424 | J:323902
 
First Author: Tian Y
Year: 2020
Journal: JCI Insight
Title: Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis.
Volume: 5
Issue: 20
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Publication
19531658 | J:151721
First Author: Yen JH
Year: 2009
Journal: Blood
Title: Interferon beta induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation.
Volume: 114
Issue: 7
Pages: 1344-54
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Publication
28939441 | J:273703
First Author: Wang J
Year: 2017
Journal: Int J Med Microbiol
Title: Caspase-11 deficiency impairs neutrophil recruitment and bacterial clearance in the early stage of pulmonary Klebsiella pneumoniae infection.
Volume: 307
Issue: 8
Pages: 490-496
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Publication
32645232 | J:333090
First Author: Lefevere E
Year: 2020
Journal: Glia
Title: Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury.
Volume: 68
Issue: 12
Pages: 2643-2660
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Publication
15383538 | J:95190
First Author: Arai H
Year: 2004
Journal: J Biol Chem
Title: Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice.
Volume: 279
Issue: 49
Pages: 51647-53
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Publication
30625325 | J:287709
First Author: de Carvalho RVH
Year: 2019
Journal: Cell Rep
Title: Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome.
Volume: 26
Issue: 2
Pages: 429-437.e5
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Publication
37316487 | J:338417
First Author: Ryan TAJ
Year: 2023
Journal: Nat Commun
Title: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Volume: 14
Issue: 1
Pages: 3513
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Publication
30538296 | J:295056
First Author: Flood B
Year: 2019
Journal: Oncogene
Title: Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis.
Volume: 38
Issue: 14
Pages: 2658-2674
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Publication
32109412 | J:296118
First Author: Wang K
Year: 2020
Journal: Cell
Title: Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Volume: 180
Issue: 5
Pages: 941-955.e20
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Publication
24312444 | J:209749
First Author: Hendrikx T
Year: 2013
Journal: PLoS One
Title: Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.
Volume: 8
Issue: 12
Pages: e78792
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Publication
37314361 | J:355521
First Author: Thomas SM
Year: 2023
Journal: Infect Immun
Title: High Lethality of Mycobacterium tuberculosis Infection in Mice Lacking the Phagocyte Oxidase and Caspase1/11.
Volume: 91
Issue: 7
Pages: e0006023
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Publication
33640898 | J:338994
First Author: Yuan C
Year: 2021
Journal: Signal Transduct Target Ther
Title: Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis.
Volume: 6
Issue: 1
Pages: 92
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Publication
29038248 | J:254288
First Author: Hagar JA
Year: 2017
Journal: J Immunol
Title: Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock.
Volume: 199
Issue: 10
Pages: 3634-3643
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Publication
24031018 | J:201144
First Author: Hagar JA
Year: 2013
Journal: Science
Title: Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.
Volume: 341
Issue: 6151
Pages: 1250-3
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Publication
35508125 | J:344029
First Author: Vasudevan SO
Year: 2022
Journal: Cell Rep
Title: A TLR4-independent critical role for CD14 in intracellular LPS sensing.
Volume: 39
Issue: 5
Pages: 110755
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Publication
31036765 | J:276859
First Author: Wang J
Year: 2019
Journal: J Immunol
Title: Gasdermin D Protects from Melioidosis through Pyroptosis and Direct Killing of Bacteria.
Volume: 202
Issue: 12
Pages: 3468-3473
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Publication
25367751 | J:222315
First Author: Desbien AL
Year: 2015
Journal: Eur J Immunol
Title: Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ.
Volume: 45
Issue: 2
Pages: 407-17
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Publication
29108122 | J:337170
First Author: Khanova E
Year: 2018
Journal: Hepatology
Title: Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.
Volume: 67
Issue: 5
Pages: 1737-1753
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Publication
31440260 | J:285967
 
First Author: Chen R
Year: 2019
Journal: Front Immunol
Title: AGER-Mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis.
Volume: 10
Pages: 1904
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Publication
12232800 | J:115554
First Author: Kang SJ
Year: 2002
Journal: Cell Death Differ
Title: Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response.
Volume: 9
Issue: 10
Pages: 1115-25
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Publication
29873075 | J:273339
First Author: Burkovetskaya M
Year: 2019
Journal: J Neurochem
Title: Caspase 1 activity influences juvenile Batten disease (CLN3) pathogenesis.
Volume: 148
Issue: 5
Pages: 652-668
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Publication
31430539 | J:298109
First Author: Shutinoski B
Year: 2020
Journal: Microbes Infect
Title: Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome.
Volume: 22
Issue: 1
Pages: 40-45
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Publication
31586037 | J:282044
First Author: Chenery AL
Year: 2019
Journal: J Immunol
Title: Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung.
Volume: 203
Issue: 10
Pages: 2724-2734
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Publication
30930743 | J:310545
 
First Author: Pronin A
Year: 2019
Journal: Front Mol Neurosci
Title: Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury.
Volume: 12
Pages: 36
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Publication
24630989 | J:211710
First Author: Py BF
Year: 2014
Journal: Cell Rep
Title: Caspase-11 controls interleukin-1β release through degradation of TRPC1.
Volume: 6
Issue: 6
Pages: 1122-1128
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Publication
37373111 | J:337467
 
First Author: Aresta Branco MSL
Year: 2023
Journal: Int J Mol Sci
Title: The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria.
Volume: 24
Issue: 12
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Publication
29866797 | J:280160
First Author: Jankowski J
Year: 2018
Journal: J Am Soc Nephrol
Title: Epithelial and Endothelial Pannexin1 Channels Mediate AKI.
Volume: 29
Issue: 7
Pages: 1887-1899
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Publication
22332634 | J:184293
First Author: Kenneth NS
Year: 2012
Journal: Biochem J
Title: An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.
Volume: 443
Issue: 2
Pages: 355-9
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Publication
32332915 | J:302787
First Author: Liu J
Year: 2020
Journal: Cell Death Differ
Title: HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression.
Volume: 27
Issue: 9
Pages: 2651-2667
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Publication
37001519 | J:334741
First Author: Zhu F
Year: 2023
Journal: Immunity
Title: The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome.
Volume: 56
Issue: 4
Pages: 753-767.e8
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15880263 | J:99484
First Author: Yin YB
Year: 2005
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Comparative study of apoptosis-related gene loci in human, mouse and rat genomes.
Volume: 37
Issue: 5
Pages: 341-8
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Publication
16380090 | J:104736
First Author: Islam S
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells.
Volume: 340
Issue: 2
Pages: 589-96
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Publication
25162221 | J:221077
First Author: Breyne K
Year: 2014
Journal: PLoS One
Title: Non-classical proIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent.
Volume: 9
Issue: 8
Pages: e105680
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Publication
31405732 | J:297425
First Author: Miao N
Year: 2019
Journal: Kidney Int
Title: The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury.
Volume: 96
Issue: 5
Pages: 1105-1120
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Publication
29774028 | J:313212
 
First Author: Paroli AF
Year: 2018
Journal: Front Immunol
Title: NLRP3 Inflammasome and Caspase-1/11 Pathway Orchestrate Different Outcomes in the Host Protection Against Trypanosoma cruzi Acute Infection.
Volume: 9
Pages: 913
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Publication
30692621 | J:273511
First Author: Choi YJ
Year: 2019
Journal: Nat Immunol
Title: SERPINB1-mediated checkpoint of inflammatory caspase activation.
Volume: 20
Issue: 3
Pages: 276-287
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Publication
26375003 | J:226781
First Author: Shi J
Year: 2015
Journal: Nature
Title: Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Volume: 526
Issue: 7575
Pages: 660-5
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25121752 | J:244803
First Author: Knodler LA
Year: 2014
Journal: Cell Host Microbe
Title: Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens.
Volume: 16
Issue: 2
Pages: 249-256
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Publication
26814970 | J:229240
First Author: He Y
Year: 2016
Journal: Nature
Title: NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Volume: 530
Issue: 7590
Pages: 354-7
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23226472 | J:192443
First Author: Hesker PR
Year: 2012
Journal: PLoS One
Title: Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels.
Volume: 7
Issue: 11
Pages: e51105
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Publication
26216893 | J:324561
First Author: Douglas T
Year: 2015
Journal: J Immunol
Title: The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
Volume: 195
Issue: 5
Pages: 2365-73
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Publication
36652908 | J:347650
First Author: Muñoz-Wolf N
Year: 2023
Journal: Cell Rep Med
Title: Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles.
Volume: 4
Issue: 1
Pages: 100899
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Publication
32477361 | J:336936
 
First Author: Winchell CG
Year: 2020
Journal: Front Immunol
Title: Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques.
Volume: 11
Pages: 891
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Publication
34867993 | J:316444
 
First Author: Chowdhury D
Year: 2021
Journal: Front Immunol
Title: Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity.
Volume: 12
Pages: 755961
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Publication
29358279 | J:258416
First Author: Deigendesch N
Year: 2018
Journal: J Immunol
Title: Copper Regulates the Canonical NLRP3 Inflammasome.
Volume: 200
Issue: 5
Pages: 1607-1617
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Publication
31064994 | J:275572
First Author: Tsuchiya K
Year: 2019
Journal: Nat Commun
Title: Caspase-1 initiates apoptosis in the absence of gasdermin D.
Volume: 10
Issue: 1
Pages: 2091
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Publication
26173909 | J:233045
First Author: Rühl S
Year: 2015
Journal: Eur J Immunol
Title: Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux.
Volume: 45
Issue: 10
Pages: 2927-36
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Publication
29539421 | J:270873
First Author: Kambara H
Year: 2018
Journal: Cell Rep
Title: Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
Volume: 22
Issue: 11
Pages: 2924-2936
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Publication
32002713 | J:296047
First Author: Mirea AM
Year: 2020
Journal: Inflammation
Title: Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.
Volume: 43
Issue: 3
Pages: 1054-1064
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Publication
29735414 | J:268973
 
First Author: Zhang SY
Year: 2018
Journal: EBioMedicine
Title: Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance.
Volume: 31
Pages: 202-216
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Publication
25738962 | J:245859
First Author: Zhu W
Year: 2015
Journal: PLoS Pathog
Title: Sensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infection.
Volume: 11
Issue: 3
Pages: e1004704
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Publication
29972777 | J:270686
First Author: Liu BC
Year: 2018
Journal: Cell Rep
Title: Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses.
Volume: 24
Issue: 1
Pages: 155-168.e5
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Publication
30133699 | J:267406
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