| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161626 |
| Age: |
postnatal week 12 |
| Image: |
3 |
|
| Specimen Label: |
Adult heart |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161627 |
| Age: |
postnatal week 12 |
| Image: |
3 |
|
| Specimen Label: |
Adult testis |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797227 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:6161627 |
| Age: |
postnatal newborn |
| Image: |
3 |
|
| Specimen Label: |
Testis n.b |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161627 |
| Age: |
postnatal week 1 |
| Image: |
3 |
|
| Specimen Label: |
Testis 1w |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161627 |
| Age: |
postnatal week 2 |
| Image: |
3 |
|
| Specimen Label: |
Testis 2w |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161627 |
| Age: |
postnatal week 3 |
| Image: |
3 |
|
| Specimen Label: |
Testis 3w |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161552 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161627 |
| Age: |
postnatal week 4 |
| Image: |
3 |
|
| Specimen Label: |
Testis 4w |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2018-06-19 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161630 |
| Age: |
postnatal week 12 |
| Image: |
4 |
|
| Specimen Label: |
Testis |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2018-06-19 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161630 |
| Age: |
postnatal week 12 |
| Image: |
4 |
|
| Specimen Label: |
Heart |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161685 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
Adult testis |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3148428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161685 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
ps |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3148628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161685 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
rs |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3148628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161685 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
es |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161687 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
T |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:3148828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161703 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
sp |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161549 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161703 |
| Age: |
postnatal week 12 |
| Image: |
5 |
|
| Specimen Label: |
gc |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161726 |
| Age: |
postnatal week 12 |
| Image: |
S2 |
|
| Specimen Label: |
Testis |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2018-06-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161726 |
| Age: |
postnatal week 12 |
| Image: |
S2 |
|
| Specimen Label: |
Heart |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3148228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6161705 |
| Age: |
postnatal adult |
| Image: |
6a |
| Note: |
Expressed in the nucleus. |
| Specimen Label: |
6a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3148428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6161705 |
| Age: |
postnatal adult |
| Image: |
6a |
| Note: |
pachytene spermatocytes |
| Specimen Label: |
6a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:2910628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6161705 |
| Age: |
postnatal adult |
| Image: |
6a |
| Note: |
Expressed in the nucleus. |
| Specimen Label: |
6a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:2965528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6161705 |
| Age: |
postnatal adult |
| Image: |
6a |
| Note: |
Expressed in the nucleus. |
| Specimen Label: |
6a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-06-20 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3148628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6161705 |
| Age: |
postnatal adult |
| Image: |
6a |
| Note: |
round spermatids |
| Specimen Label: |
6a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6161566 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-06-20 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:3148828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:6161705 |
| Age: |
postnatal adult |
| Image: |
6a |
|
| Specimen Label: |
6a |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Podlaha O |
| Year: |
2005 |
| Journal: |
Mol Biol Evol |
| Title: |
Positive selection for indel substitutions in the rodent sperm protein catsper1. |
| Volume: |
22 |
| Issue: |
9 |
| Pages: |
1845-52 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vicens A |
| Year: |
2014 |
| Journal: |
BMC Evol Biol |
| Title: |
Structural evolution of CatSper1 in rodents is influenced by sperm competition, with effects on sperm swimming velocity. |
| Volume: |
14 |
|
| Pages: |
106 |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Dejian Ren |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen Y |
| Year: |
2007 |
| Journal: |
Neuroscience |
| Title: |
Site-directed antibodies to low-voltage-activated calcium channel CaV3.3 (alpha1I) subunit also target neural cell adhesion molecule-180. |
| Volume: |
145 |
| Issue: |
3 |
| Pages: |
981-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu XB |
| Year: |
2011 |
| Journal: |
J Comp Neurol |
| Title: |
Low-threshold calcium channel subunit Ca(v) 3.3 is specifically localized in GABAergic neurons of rodent thalamus and cerebral cortex. |
| Volume: |
519 |
| Issue: |
6 |
| Pages: |
1181-95 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry represents the T-type voltage-dependent calcium channel alpha-1I subtype, also known as Cav3.3. Sperm-specific CatSper1 and CatSper2 proteins can associate with and modulate the function of this channel, which might be important in the regulation of sperm motility []. It may also play a role in regulating GABAergic neurons [].Voltage-dependent calcium channels (VDCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. T-type VDCC belongs to low-voltage-activated (LVA) Ca2+ channels, whereas others belong to high-voltage-activated (HVA) Ca2+ channels.VDCCs consist of subunits. The alpha-1 subunit constitute the pore region which determines the fundamental channel properties []. Three types of alpha-1 subunit have been identified in T-type VDCCs molecules: alpha-1G [], alpha-1H [], and alpha-1I []. T-currents generated by the alpha-1I subunit display slow kinetics that differ markedly from the alpha-1G and alpha-1H currents [, , ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jin J |
| Year: |
2007 |
| Journal: |
Biol Reprod |
| Title: |
Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse. |
| Volume: |
77 |
| Issue: |
1 |
| Pages: |
37-44 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jin JL |
| Year: |
2005 |
| Journal: |
Biol Reprod |
| Title: |
Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis. |
| Volume: |
73 |
| Issue: |
6 |
| Pages: |
1235-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lim S |
| Year: |
2019 |
| Journal: |
Endocrinology |
| Title: |
CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility. |
| Volume: |
160 |
| Issue: |
4 |
| Pages: |
915-924 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cribbs LL |
| Year: |
1998 |
| Journal: |
Circ Res |
| Title: |
Cloning and characterization of alpha1H from human heart, a member of the T-type Ca2+ channel gene family. |
| Volume: |
83 |
| Issue: |
1 |
| Pages: |
103-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Isom LL |
| Year: |
1994 |
| Journal: |
Neuron |
| Title: |
Auxiliary subunits of voltage-gated ion channels. |
| Volume: |
12 |
| Issue: |
6 |
| Pages: |
1183-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Monteil A |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Molecular and functional properties of the human alpha(1G) subunit that forms T-type calcium channels. |
| Volume: |
275 |
| Issue: |
9 |
| Pages: |
6090-100 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Monteil A |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Specific properties of T-type calcium channels generated by the human alpha 1I subunit. |
| Volume: |
275 |
| Issue: |
22 |
| Pages: |
16530-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Klöckner U |
| Year: |
1999 |
| Journal: |
Eur J Neurosci |
| Title: |
Comparison of the Ca2 + currents induced by expression of three cloned alpha1 subunits, alpha1G, alpha1H and alpha1I, of low-voltage-activated T-type Ca2 + channels. |
| Volume: |
11 |
| Issue: |
12 |
| Pages: |
4171-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McRory JE |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Molecular and functional characterization of a family of rat brain T-type calcium channels. |
| Volume: |
276 |
| Issue: |
6 |
| Pages: |
3999-4011 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
174
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
260
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2199
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1835
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|