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Search results 201 to 300 out of 439 for Cblc

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Type Details Score
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_07
Specimen Label: euxassay_004794_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_08
Specimen Label: euxassay_004794_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_09
Specimen Label: euxassay_004794_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_10
Specimen Label: euxassay_004794_10
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5001563
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542117
Age: embryonic day 15.5
Image: GUDMAP:10193
Specimen Label: GUDMAP:10193
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001563
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542117
Age: embryonic day 15.5
Image: GUDMAP:10212
Specimen Label: GUDMAP:10212
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5001563
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542117
Age: embryonic day 15.5
Image: GUDMAP:10212
Specimen Label: GUDMAP:10212
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_13
Specimen Label: euxassay_004794_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_17
Specimen Label: euxassay_004794_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_18
Specimen Label: euxassay_004794_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1789623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_13
Specimen Label: euxassay_004794_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1789623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_14
Specimen Label: euxassay_004794_14
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:5001563
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542117
Age: embryonic day 15.5
Image: GUDMAP:10193
Specimen Label: GUDMAP:10193
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001563
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542117
Age: embryonic day 15.5
Image: GUDMAP:10212
Specimen Label: GUDMAP:10212
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3794975
Assay Type: RNA in situ
Annotation Date: 2008-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3794986
Age: postnatal adult
Specimen Label: 4 Brain
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:5001563
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542117
Age: embryonic day 15.5
Image: GUDMAP:10212
Specimen Label: GUDMAP:10212
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_10
Specimen Label: euxassay_004794_10
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3794975
Assay Type: RNA in situ
Annotation Date: 2008-06-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3794986
Age: embryonic day 14.5
Specimen Label: 3 Head x40
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_09
Specimen Label: euxassay_004794_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_10
Specimen Label: euxassay_004794_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_11
Specimen Label: euxassay_004794_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_12
Specimen Label: euxassay_004794_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_13
Specimen Label: euxassay_004794_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_14
Specimen Label: euxassay_004794_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_15
Specimen Label: euxassay_004794_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_16
Specimen Label: euxassay_004794_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_17
Specimen Label: euxassay_004794_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:2058646
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823652
Age: embryonic day 14.5
Image: euxassay_004794_18
Specimen Label: euxassay_004794_18
Detected: true
Specimen Num: 18
Publication
First Author: Daniels SR
Year: 2019
Journal: PLoS One
Title: Loss of function Cbl-c mutations in solid tumors.
Volume: 14
Issue: 7
Pages: e0219143
Publication
First Author: Zhang J
Year: 2004
Journal: J Immunol
Title: Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.
Volume: 173
Issue: 3
Pages: 1811-8
Publication
First Author: Penn BH
Year: 2018
Journal: Mol Cell
Title: An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.
Volume: 71
Issue: 4
Pages: 637-648.e5
Publication
First Author: Dale BM
Year: 2009
Journal: J Immunol
Title: Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.
Volume: 182
Issue: 9
Pages: 5654-62
Publication
First Author: Tsui CC
Year: 2008
Journal: J Neurosci
Title: CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.
Volume: 28
Issue: 35
Pages: 8789-800
Publication
First Author: Loreto MP
Year: 2002
Journal: Mol Cell Biol
Title: Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
Volume: 22
Issue: 12
Pages: 4241-55
Publication
First Author: Purev E
Year: 2009
Journal: Mol Biol Cell
Title: c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes.
Volume: 20
Issue: 18
Pages: 4021-30
Publication  
First Author: Zhang X
Year: 2019
Journal: Exp Eye Res
Title: Loss-of-function mutations in FREM2 disrupt eye morphogenesis.
Volume: 181
Pages: 302-312
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Gene
Type: gene
Organism: chicken
Genotype
Symbol: Mmachc/Mmachc<+>
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Kiessling E
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Absence of MMACHC in peripheral retinal cells does not lead to an ocular phenotype in mice.
Volume: 1867
Issue: 10
Pages: 166201
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Moreno-Garcia MA
Year: 2014
Journal: Mol Genet Metab
Title: The Mmachc gene is required for pre-implantation embryogenesis in the mouse.
Volume: 112
Issue: 3
Pages: 198-204
Allele
Name: THAP domain containing 11; endonuclease-mediated mutation 1, Ross Poche
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
Publication
First Author: Koutmos M
Year: 2011
Journal: J Biol Chem
Title: Structural basis of multifunctionality in a vitamin B12-processing enzyme.
Volume: 286
Issue: 34
Pages: 29780-7
Publication
First Author: Kim J
Year: 2009
Journal: J Biol Chem
Title: A human vitamin B12 trafficking protein uses glutathione transferase activity for processing alkylcobalamins.
Volume: 284
Issue: 48
Pages: 33418-24
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
DO Term
Genotype
Symbol: Thap11/Thap11
Background: C57BL/6J-Thap11
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Lerner-Ellis JP
Year: 2006
Journal: Nat Genet
Title: Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type.
Volume: 38
Issue: 1
Pages: 93-100
Protein
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
Publication
First Author: Gherasim C
Year: 2013
Journal: Biochimie
Title: The C-terminal domain of CblD interacts with CblC and influences intracellular cobalamin partitioning.
Volume: 95
Issue: 5
Pages: 1023-32
Allele  
Name: methylmalonic aciduria cblC type, with homocystinuria; wild type
Allele Type: Not Specified
Allele  
Name: methylmalonic aciduria cblC type, with homocystinuria; gene trap CSH052, BayGenomics
Allele Type: Gene trapped
Allele
Name: methylmalonic aciduria cblC type, with homocystinuria; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: methylmalonic aciduria cblC type, with homocystinuria; endonuclease-mediated mutation 1, GemPharmatech
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory