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Search results 201 to 300 out of 323 for Ccr9

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Type Details Score
Publication
16129397 | J:101029
First Author: Lieberam I
Year: 2005
Journal: Neuron
Title: A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons.
Volume: 47
Issue: 5
Pages: 667-79
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Publication
12080938 | J:76755
First Author: IUIS/WHO Subcommittee on Chemokine Nomenclature.
Year: 2002
Journal: J Immunol Methods
Title: Chemokine/chemokine receptor nomenclature.
Volume: 262
Issue: 1-2
Pages: 1-3
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Publication
- | J:169366
     
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
16365398 | J:126252
First Author: Uehara S
Year: 2006
Journal: J Immunol
Title: Premature expression of chemokine receptor CCR9 impairs T cell development.
Volume: 176
Issue: 1
Pages: 75-84
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Publication
18453568 | J:134963
First Author: Elgueta R
Year: 2008
Journal: J Immunol
Title: Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells.
Volume: 180
Issue: 10
Pages: 6501-7
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Publication
31755547 | J:288853
First Author: Pathak M
Year: 2020
Journal: Eur J Immunol
Title: CCR9 signaling in dendritic cells drives the differentiation of Foxp3+ Tregs and suppresses the allergic IgE response in the gut.
Volume: 50
Issue: 3
Pages: 404-417
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Publication
31712385 | J:282212
First Author: Park C
Year: 2019
Journal: J Immunol
Title: Obesity Modulates Intestinal Intraepithelial T Cell Persistence, CD103 and CCR9 Expression, and Outcome in Dextran Sulfate Sodium-Induced Colitis.
Volume: 203
Issue: 12
Pages: 3427-3435
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Publication
15623660 | -
First Author: Singh S
Year: 2004
Journal: Clin Cancer Res
Title: Expression and functional role of CCR9 in prostate cancer cell migration and invasion.
Volume: 10
Issue: 24
Pages: 8743-50
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Publication
11046037 | -
First Author: Papadakis KA
Year: 2000
Journal: J Immunol
Title: The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system.
Volume: 165
Issue: 9
Pages: 5069-76
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Allele
Ccr9<em1Smoc> | MGI:7288750
Name: C-C motif chemokine receptor 9; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
11159507 | -
First Author: Carramolino L
Year: 2001
Journal: Blood
Title: Expression of CCR9 beta-chemokine receptor is modulated in thymocyte differentiation and is selectively maintained in CD8(+) T cells from secondary lymphoid organs.
Volume: 97
Issue: 4
Pages: 850-7
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Strain
MGI:6354602 | C57BL/6JSmoc-Ccr9<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Ccr9<tm1Ccb> | MGI:3521585
Name: C-C motif chemokine receptor 9; targeted mutation 1, Conrad C Bleul
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Ccr9/Ccr9
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
25521433 | J:223243
First Author: Lucas B
Year: 2015
Journal: Eur J Immunol
Title: CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice.
Volume: 45
Issue: 2
Pages: 574-83
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Protein
A0A1L1ST82
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
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Protein Domain
IPR033037 | Ackr2
Type: Family
Description: Atypical chemokine receptor 2 (ACKR2/D6) [], previously known as CCR9 or CCR10 [], is a chemokine-scavenging receptor or chemokine decoy receptor. It is capable of internalising and effectively scavenging its ligands through beta-arrestin-dependent activation of the cofilin pathway [, ]. ACKR2 is highly promiscuous and can bind the majority of (if not all) inflammatory CC-chemokines []. It plays an essential role in the resolution of the inflammatory response [, , ]. Although it lacks the canonical DRYLAIV motif necessary for classical signalling, ACKR2/D6 may be involved in 'atypical' signalling pathways downstream of ligand binding []. It has been shown to be involved in regulating vessel density [].
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Publication
10498628 | -
First Author: Youn BS
Year: 1999
Journal: Blood
Title: TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor.
Volume: 94
Issue: 7
Pages: 2533-6
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Publication
16253981 | -
First Author: Honczarenko M
Year: 2006
Journal: Stem Cells
Title: Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors.
Volume: 24
Issue: 4
Pages: 1030-41
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Publication
11487533 | -
First Author: Papadakis KA
Year: 2001
Journal: Gastroenterology
Title: CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease.
Volume: 121
Issue: 2
Pages: 246-54
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Protein Domain
IPR004069 | Chemokine_CCR9
Type: Family
Description: Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helper cells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).CC chemokine receptors are a subfamily of the chemokine receptors that specifically bind and respond to cytokines of the CC chemokine family. There are currently ten members of the CC chemokine receptor subfamily, named CCR1 to 10. The receptors receptors are found in monocytes, lymphocytes, basophils and eosinophils.This entry represents CC chemokine receptor 9 (CCR9), which was previously designated as the orphan receptors GPR28 and GPR 9-6. CCR9 is expressed predominantly in the thymus, in both mature and immature T cells, and is also found in the lymph nodes, spleen, glomerular podocytes, bone marrow stromal cells and the small intestine [, , , , ]. Transfected cells expressing CCR9 receptor bind specifically to CCL25 (also known as Thymus-Expressed Chemokine) []. This interaction may play a pivotal role in T-cell migration in the thymus []. CCR9 activation has also been shown to influence cancer cell migration, invasion and matrix metallopeptidase expression, which together may affect prostate cancer metastasis [].
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Publication
10706668 | -
First Author: Gosling J
Year: 2000
Journal: J Immunol
Title: Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK.
Volume: 164
Issue: 6
Pages: 2851-6
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Publication
23121557 | -
First Author: Vinet J
Year: 2013
Journal: Br J Pharmacol
Title: Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR.
Volume: 168
Issue: 6
Pages: 1375-87
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Publication
16791897 | -
First Author: Comerford I
Year: 2006
Journal: Eur J Immunol
Title: The chemokine receptor CCX-CKR mediates effective scavenging of CCL19 in vitro.
Volume: 36
Issue: 7
Pages: 1904-16
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Protein Domain
IPR005383 | ACKR4
Type: Family
Description: Just like classical chemokine receptors, atypical chemokine receptors (ACKRs) are seven-transmembrane-helix (7TM) receptors that bind chemokines []. However, they lack the canonical DRYLAIV motif necessary for GPCR coupling to G proteins and induction of classical signalling pathways. Instead, ACKRs internalise their chemokine ligands, which may subsequently affect chemokine availability. The ACKR family comprises five members: Duffy Antigen Receptor for Chemokines (DARC, ACKR1), D6 (ACKR2), CXCR7 (ACKR3), CCRL1 (ACKR4) and CCRL2 (ACKR5) [].Atypical chemokine receptor 4 (ACKR4/CCRL1/CCX-CKR) binds and scavenges the ligands of the chemokine receptors CCR7 and CCR9 (CCL19/CCL21 and CCL25, respectively) and targets them for subsequent lysosomal degradation [, ]. Apart from being a scavenger for chemokines, it may prevent CXCR3-induced chemotaxis by heteromerisation []. ACKR4 appears to have a mayor role in normal thymus development and function [].
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Publication
19027330 | J:142925
First Author: Choi YI
Year: 2008
Journal: Immunity
Title: PlexinD1 glycoprotein controls migration of positively selected thymocytes into the medulla.
Volume: 29
Issue: 6
Pages: 888-98
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Publication
11750047 | J:113574
First Author: Miyazaki K
Year: 2002
Journal: Immunol Lett
Title: Chemokine-mediated thymopoiesis is regulated by a mammalian Polycomb group gene, mel-18.
Volume: 80
Issue: 2
Pages: 139-43
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Publication
39406246 | J:358114
First Author: Raynor JL
Year: 2024
Journal: Immunity
Title: CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8(+) T cell formation.
Volume: 57
Issue: 11
Pages: 2597-2614.e13
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Publication
27166946 | J:235369
First Author: Yun TJ
Year: 2016
Journal: Cell Metab
Title: Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells.
Volume: 23
Issue: 5
Pages: 852-66
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Publication
29343500 | J:263059
First Author: Tenno M
Year: 2018
Journal: J Exp Med
Title: Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.
Volume: 215
Issue: 2
Pages: 595-610
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Publication
37662923 | J:340323
 
First Author: Ishikawa J
Year: 2023
Journal: Front Immunol
Title: IL-21 is required for the maintenance and pathogenesis of murine Vγ4(+) IL-17-producing γδT cells.
Volume: 14
Pages: 1211620
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Publication
20504763 | J:165997
First Author: Abd Alla J
Year: 2010
Journal: J Biol Chem
Title: Angiotensin-converting enzyme inhibition down-regulates the pro-atherogenic chemokine receptor 9 (CCR9)-chemokine ligand 25 (CCL25) axis.
Volume: 285
Issue: 30
Pages: 23496-505
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Publication
19095793 | J:323292
First Author: Yu S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Failure of T cell homing, reduced CD4/CD8alphaalpha intraepithelial lymphocytes, and inflammation in the gut of vitamin D receptor KO mice.
Volume: 105
Issue: 52
Pages: 20834-9
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Publication
17521370 | J:125641
First Author: García-Zepeda EA
Year: 2007
Journal: Immunology
Title: Janus kinase 3-deficient T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs.
Volume: 122
Issue: 2
Pages: 247-60
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Publication
15147562 | J:90510
First Author: Soldevila G
Year: 2004
Journal: Immunology
Title: Impaired chemokine-induced migration during T-cell development in the absence of Jak 3.
Volume: 112
Issue: 2
Pages: 191-200
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Publication
24498424 | J:212843
First Author: Ambriz-Peña X
Year: 2014
Journal: PLoS One
Title: Jak3 enables chemokine-dependent actin cytoskeleton reorganization by regulating cofilin and Rac/Rhoa GTPases activation.
Volume: 9
Issue: 2
Pages: e88014
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Publication
23460729 | J:197553
First Author: Wang C
Year: 2013
Journal: J Exp Med
Title: BATF is required for normal expression of gut-homing receptors by T helper cells in response to retinoic acid.
Volume: 210
Issue: 3
Pages: 475-89
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Publication
29784760 | J:264056
First Author: Cosway EJ
Year: 2018
Journal: J Immunol
Title: Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7+ Progenitors to the Thymus.
Volume: 201
Issue: 2
Pages: 516-523
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Publication
19786532 | J:153824
First Author: Withers DR
Year: 2009
Journal: J Immunol
Title: The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals.
Volume: 183
Issue: 8
Pages: 5079-84
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Publication
21828128 | J:178408
First Author: Li HS
Year: 2011
Journal: Blood
Title: Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response.
Volume: 118
Issue: 14
Pages: 3879-89
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Publication
25527788 | J:329724
First Author: Yuan X
Year: 2015
Journal: J Immunol
Title: IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa.
Volume: 194
Issue: 3
Pages: 1334-46
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Publication
21444662 | J:177320
First Author: Stock A
Year: 2011
Journal: J Exp Med
Title: Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans.
Volume: 208
Issue: 4
Pages: 761-73
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Publication
29106985 | J:277537
 
First Author: Cédile O
Year: 2017
Journal: Immunol Lett
Title: The chemokine receptor CCR2 maintains plasmacytoid dendritic cell homeostasis.
Volume: 192
Pages: 72-78
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Publication
23960190 | J:202859
First Author: Ruane D
Year: 2013
Journal: J Exp Med
Title: Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract.
Volume: 210
Issue: 9
Pages: 1871-88
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Publication
20944006 | J:165627
First Author: Feng T
Year: 2010
Journal: J Immunol
Title: Generation of mucosal dendritic cells from bone marrow reveals a critical role of retinoic acid.
Volume: 185
Issue: 10
Pages: 5915-25
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Publication
23529927 | J:198223
First Author: Chen X
Year: 2013
Journal: Blood
Title: A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease.
Volume: 121
Issue: 19
Pages: 3970-80
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Publication
27465532 | J:299351
First Author: Golec DP
Year: 2016
Journal: J Immunol
Title: RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors.
Volume: 197
Issue: 5
Pages: 1743-53
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Publication
27402696 | J:359136
First Author: Chen LC
Year: 2016
Journal: J Immunol
Title: A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.
Volume: 197
Issue: 4
Pages: 1137-47
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Publication
17404232 | J:131942
First Author: Lai AY
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Identification of a bone marrow precursor of the earliest thymocytes in adult mouse.
Volume: 104
Issue: 15
Pages: 6311-6
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Publication
24316973 | J:207910
First Author: Califano D
Year: 2014
Journal: J Clin Invest
Title: Diverting T helper cell trafficking through increased plasticity attenuates autoimmune encephalomyelitis.
Volume: 124
Issue: 1
Pages: 174-87
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Publication
18586982 | J:140232
First Author: Webb A
Year: 2008
Journal: J Leukoc Biol
Title: Evidence for PI-3K-dependent migration of Th17-polarized cells in response to CCR2 and CCR6 agonists.
Volume: 84
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