Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
23 |
Description: |
T-cell surface antigen CD2 |
Type: |
chain |
End: |
344 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
23 |
Description: |
T-cell surface antigen CD2 |
Type: |
chain |
End: |
344 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
23 |
Description: |
T-cell surface antigen CD2 |
Type: |
chain |
End: |
344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beil-Wagner J |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
T cell-specific inactivation of mouse CD2 by CRISPR/Cas9. |
Volume: |
6 |
|
Pages: |
21377 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson TJ |
Year: |
2002 |
Journal: |
Genesis |
Title: |
A human CD2 minigene directs CRE-mediated recombination in T cells in vivo. |
Volume: |
33 |
Issue: |
4 |
Pages: |
181-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Turner SD |
Year: |
2006 |
Journal: |
Anticancer Res |
Title: |
CD2 promoter regulated nucleophosmin-anaplastic lymphoma kinase in transgenic mice causes B lymphoid malignancy. |
Volume: |
26 |
Issue: |
5A |
Pages: |
3275-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stewart M |
Year: |
1993 |
Journal: |
Int J Cancer |
Title: |
Conditional expression and oncogenicity of c-myc linked to a CD2 gene dominant control region. |
Volume: |
53 |
Issue: |
6 |
Pages: |
1023-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fennelly JA |
Year: |
2001 |
Journal: |
Immunogenetics |
Title: |
CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily. |
Volume: |
53 |
Issue: |
7 |
Pages: |
599-602 |
|
•
•
•
•
•
|
Publication |
First Author: |
Badour K |
Year: |
2003 |
Journal: |
Immunity |
Title: |
The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. |
Volume: |
18 |
Issue: |
1 |
Pages: |
141-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Punch JD |
Year: |
1999 |
Journal: |
Transplantation |
Title: |
CD2 and CD3 receptor-mediated tolerance: constraints on T cell activation. |
Volume: |
67 |
Issue: |
5 |
Pages: |
741-8 |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Peck SR |
Year: |
2000 |
Journal: |
Immunogenetics |
Title: |
Ly108: a new member of the mouse CD2 family of cell surface proteins. |
Volume: |
52 |
Issue: |
1-2 |
Pages: |
63-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhumabekov T |
Year: |
1995 |
Journal: |
J Immunol Methods |
Title: |
Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice. |
Volume: |
185 |
Issue: |
1 |
Pages: |
133-40 |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
CD2 antigen cytoplasmic tail-binding protein 2 |
Type: |
chain |
End: |
342 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kingsbury GA |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Cloning, expression, and function of BLAME, a novel member of the CD2 family. |
Volume: |
166 |
Issue: |
9 |
Pages: |
5675-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lang G |
Year: |
1988 |
Journal: |
EMBO J |
Title: |
The structure of the human CD2 gene and its expression in transgenic mice. |
Volume: |
7 |
Issue: |
6 |
Pages: |
1675-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tavernor AS |
Year: |
1994 |
Journal: |
Eur J Biochem |
Title: |
Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA. Structure-based analysis of conserved sequence elements. |
Volume: |
219 |
Issue: |
3 |
Pages: |
969-76 |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertazzon M |
Year: |
2024 |
Journal: |
Front Immunol |
Title: |
The nuclear GYF protein CD2BP2/U5-52K is required for T cell homeostasis. |
Volume: |
15 |
|
Pages: |
1415839 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nielsen TK |
Year: |
2007 |
Journal: |
J Mol Biol |
Title: |
Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). |
Volume: |
369 |
Issue: |
4 |
Pages: |
902-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Laggerbauer B |
Year: |
2005 |
Journal: |
RNA |
Title: |
The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation. |
Volume: |
11 |
Issue: |
5 |
Pages: |
598-608 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bialkowska A |
Year: |
2002 |
Journal: |
Yeast |
Title: |
Proteins interacting with Lin 1p, a putative link between chromosome segregation, mRNA splicing and DNA replication in Saccharomyces cerevisiae. |
Volume: |
19 |
Issue: |
15 |
Pages: |
1323-33 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
CD2BP2, also known as U5-52K or LIN1, is a component of the U5 snRNP complex and acts as a splicing factor [, ]. It also may play a role in the immune response as CD2 receptor binding protein 2 (CD2BP2) []. Lin1 from Saccharomyces cerevisiae is a non-essential component of U5 snRNP []; it may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication []. |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; wild type |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pepermans E |
Year: |
2014 |
Journal: |
EMBO Mol Med |
Title: |
The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells. |
Volume: |
6 |
Issue: |
7 |
Pages: |
984-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoh K |
Year: |
2012 |
Journal: |
Eur J Immunol |
Title: |
Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice. |
Volume: |
42 |
Issue: |
8 |
Pages: |
1999-2009 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
48
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
79
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; gene trap OST7358, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; endonuclease-mediated mutation 2, Cyagen Biosciences |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
de la Fuente MA |
Year: |
1999 |
Journal: |
Immunogenetics |
Title: |
Molecular cloning, characterization, and chromosomal localization of the mouse homologue of CD84, a member of the CD2 family of cell surface molecules. |
Volume: |
49 |
Issue: |
4 |
Pages: |
249-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boles KS |
Year: |
2001 |
Journal: |
Immunol Rev |
Title: |
2B4 (CD244) and CS1: novel members of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer cells and other leukocytes. |
Volume: |
181 |
|
Pages: |
234-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clements JL |
Year: |
1994 |
Journal: |
Eur J Immunol |
Title: |
Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression. |
Volume: |
24 |
Issue: |
3 |
Pages: |
558-65 |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; targeted mutation 1, Dan R Littman |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; wild type |
|
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap XD007, BayGenomics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap XM140, BayGenomics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; gene trap 300A8, Centre for Modeling Human Disease |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 antigen; endonuclease-mediated mutation 20, GemPharmatech Co., Ltd |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
342
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
346
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap D094F01, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap OST58558, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap OST77074, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap OST187882, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap OST234561, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap W205A07, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap P053F07, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap EUCE00143b05, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap EUCJ0013a01, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; gene trap 419H6, Centre for Modeling Human Disease |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; targeted mutation 1, Mouse Biology Program, UC Davis |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; targeted mutation 1.1, Tobias Huber |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; targeted mutation 1.2, Tobias Huber |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
CD2 cytoplasmic tail binding protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd2/Cd2 |
Background: |
involves: 129S2/SvPas * C57BL/6 * DBA/2 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang H |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transduction. |
Volume: |
276 |
Issue: |
22 |
Pages: |
18775-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borca MV |
Year: |
1994 |
Journal: |
Virology |
Title: |
An African swine fever virus gene with similarity to the T-lymphocyte surface antigen CD2 mediates hemadsorption. |
Volume: |
199 |
Issue: |
2 |
Pages: |
463-8 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|