| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gu Z |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0121550 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Freeman TC |
| Year: |
1998 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Expression Mapping of Mouse Genes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
| Year: |
1993 |
|
| Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shanghai Model Organisms Center |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Velocigene |
| Year: |
2008 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koscielny G |
| Year: |
2014 |
| Journal: |
Nucleic Acids Res |
| Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
| Volume: |
42 |
| Issue: |
Database issue |
| Pages: |
D802-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
22 |
| Description: |
B-cell receptor CD22 |
| Type: |
chain |
| End: |
868 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
868
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
868
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wilson GL |
| Year: |
1993 |
| Journal: |
J Immunol |
| Title: |
Genomic structure and chromosomal mapping of the human CD22 gene. |
| Volume: |
150 |
| Issue: |
11 |
| Pages: |
5013-24 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
828
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
800
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
95
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
663
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
147
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
353
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
49
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
36
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; mutation 2, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kelm S |
| Year: |
1994 |
| Journal: |
Curr Biol |
| Title: |
Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily. |
| Volume: |
4 |
| Issue: |
11 |
| Pages: |
965-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tateno H |
| Year: |
2007 |
| Journal: |
Mol Cell Biol |
| Title: |
Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity. |
| Volume: |
27 |
| Issue: |
16 |
| Pages: |
5699-710 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mizuno K |
| Year: |
2005 |
| Journal: |
Eur J Immunol |
| Title: |
SLP-76 is recruited to CD22 and dephosphorylated by SHP-1, thereby regulating B cell receptor-induced c-Jun N-terminal kinase activation. |
| Volume: |
35 |
| Issue: |
2 |
| Pages: |
644-54 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, chemically induced mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
chemically induced mutation, coisogenic, mutant strain |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cd22/Cd22 |
| Background: |
C57BL/6J-Cd22 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Pathway |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; wild type |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alborzian Deh Sheikh A |
| Year: |
2021 |
| Journal: |
J Immunol |
| Title: |
The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells. |
| Volume: |
206 |
| Issue: |
11 |
| Pages: |
2544-2551 |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; mutation 1, Australian National University |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; mutation 1, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1, Velocigene |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1, Lars Nitschke |
| Allele Type: |
Targeted |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 2, Lars Nitschke |
| Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 3, Lars Nitschke |
| Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; mtutaion 3, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; mutation 4, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; mutation 5, Bruce Beutler |
| Allele Type: |
Chemically induced (ENU) |
| Attribute String: |
Not Specified |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; endonuclease-mediated mutation 1, Yang Liu |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; endonuclease-mediated mutation 2, Yang Liu |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; endonuclease-mediated mutation 2, GemPharmatech |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chan VW |
| Year: |
1998 |
| Journal: |
Curr Biol |
| Title: |
Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes. |
| Volume: |
8 |
| Issue: |
10 |
| Pages: |
545-53 |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1, Edward A Clark |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1, Marinus C Lamers |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1, Thomas F Tedder |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1, Michael S Neuberger |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 2, Thomas F Tedder |
| Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 3, Thomas F Tedder |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1a, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
CD22 antigen; targeted mutation 1e, Wellcome Trust Sanger Institute |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, chemically induced mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
chemically induced mutation, coisogenic, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, chemically induced mutation, coisogenic |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, chemically induced mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, chemically induced mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, chemically induced mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, coisogenic, chemically induced mutation |
|
•
•
•
•
•
|