| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_12 |
|
| Specimen Label: |
euxassay_006791_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_13 |
|
| Specimen Label: |
euxassay_006791_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1697923 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_14 |
|
| Specimen Label: |
euxassay_006791_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1690823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_10 |
|
| Specimen Label: |
euxassay_006791_10 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1690823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_11 |
|
| Specimen Label: |
euxassay_006791_11 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4880698 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-01-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616415 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4880699 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_05 |
|
| Specimen Label: |
euxassay_006791_05 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_06 |
|
| Specimen Label: |
euxassay_006791_06 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_13 |
|
| Specimen Label: |
euxassay_006791_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4823755 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006791_14 |
|
| Specimen Label: |
euxassay_006791_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1609219 |
| Pattern: |
Widespread |
| Stage: |
TS19 |
| Assay Id: |
MGI:4944761 |
| Age: |
embryonic day 11.5 |
| Image: |
g00179 E11.5 |
|
| Specimen Label: |
g00179 E11.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266028 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 7 |
| Image: |
g00179 P7 |
|
| Specimen Label: |
g00179 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266028 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 42 |
| Image: |
g00179 Adult |
|
| Specimen Label: |
g00179 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4880698 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-01-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666315 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4880699 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-08-31 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7522790 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Supplementary table 2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3028138 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2004-02-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3028322 |
| Age: |
postnatal adult |
|
| Note: |
Neuronal expression. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754028 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 7 |
| Image: |
g00179 P7 |
|
| Specimen Label: |
g00179 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754028 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 42 |
| Image: |
g00179 Adult |
|
| Specimen Label: |
g00179 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3028138 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2004-02-18 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3028322 |
| Age: |
postnatal adult |
|
| Note: |
Neuronal expression. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 7 |
| Image: |
g00179 P7 |
|
| Specimen Label: |
g00179 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 42 |
| Image: |
g00179 Adult |
|
| Specimen Label: |
g00179 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5444378 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-12-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611717 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5444380 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Expression observed is similar to that seen at E9.5. |
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5444378 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-12-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1611715 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:5444393 |
| Age: |
embryonic day 9.5 |
| Image: |
1H |
| Note: |
Expression is enhanced in this tissue. |
| Specimen Label: |
1H |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5444378 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-12-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1620115 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:5444380 |
| Age: |
embryonic day 9.5 |
| Image: |
1F |
| Note: |
There is enhanced expression in the aortic arch artery. |
| Specimen Label: |
1F |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5444378 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-12-04 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3275015 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:5444380 |
| Age: |
embryonic day 9.5 |
| Image: |
1F |
| Note: |
Expression is present in the groove between the second and third pharyngeal arches. |
| Specimen Label: |
1F |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266523 |
| Pattern: |
Widespread |
| Stage: |
TS23 |
| Assay Id: |
MGI:4944761 |
| Age: |
embryonic day 15.5 |
| Image: |
g00179 E15.5 |
|
| Specimen Label: |
g00179 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:665479 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-11-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619117 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:5295406 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4880698 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-01-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1608915 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4880699 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4944761 |
| Age: |
embryonic day 15.5 |
| Image: |
g00179 E15.5 |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g00179 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 7 |
| Image: |
g00179 P7 |
|
| Specimen Label: |
g00179 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4884974 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4944761 |
| Age: |
postnatal day 42 |
| Image: |
g00179 Adult |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g00179 Adult |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4880698 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-01-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689420 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4880699 |
| Age: |
embryonic day 12.5 |
|
|
| Specimen Label: |
3D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4880698 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-01-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4880699 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
3F |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kunte A |
| Year: |
2001 |
| Journal: |
Mech Dev |
| Title: |
A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L. |
| Volume: |
108 |
| Issue: |
1-2 |
| Pages: |
81-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamagishi H |
| Year: |
1999 |
| Journal: |
Science |
| Title: |
A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. |
| Volume: |
283 |
| Issue: |
5405 |
| Pages: |
1158-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Devaraju P |
| Year: |
2017 |
| Journal: |
Mol Psychiatry |
| Title: |
Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium. |
| Volume: |
22 |
| Issue: |
9 |
| Pages: |
1313-1326 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sutherland HF |
| Year: |
1998 |
| Journal: |
Genomics |
| Title: |
Cloning and comparative mapping of the DiGeorge syndrome critical region in the mouse. |
| Volume: |
52 |
| Issue: |
1 |
| Pages: |
37-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Capellini TD |
| Year: |
2008 |
| Journal: |
Genesis |
| Title: |
Conservation of notochord gene expression across chordates: insights from the Leprecan gene family. |
| Volume: |
46 |
| Issue: |
11 |
| Pages: |
683-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kafer GR |
| Year: |
2020 |
| Journal: |
Front Cell Dev Biol |
| Title: |
A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis. |
| Volume: |
8 |
|
| Pages: |
416 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Puech A |
| Year: |
2000 |
| Journal: |
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MGI Direct Data Submission |
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Wellcome Trust Sanger Institute |
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MGI Direct Data Submission |
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2006 |
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PLoS Biol |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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Mouse Gene Trap Data Load from dbGSS |
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Mouse Genome Informatics Scientific Curators |
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Mouse Genome Database and National Center for Biotechnology Information |
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Allen Institute for Brain Science |
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Allen Institute |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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Database Download |
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Consensus CDS project |
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Mouse Genome Informatics Scientific Curators |
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Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Mouse Genome Informatics |
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Mouse Genome Informatics Scientific Curators |
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Mouse Genome Informatics Scientific Curators |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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EMBO J |
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Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae. |
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20 |
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8 |
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2097-107 |
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Tanaka S |
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2011 |
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Curr Biol |
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21 |
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24 |
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2055-63 |
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•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Sld3 interacts with Cdc45 and plays a role in chromosomal DNA replication [, ]. |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion NJ81, GENSAT Project at Rockefeller University |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
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•
•
•
•
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| Publication |
| First Author: |
Balestrini A |
| Year: |
2010 |
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Nat Cell Biol |
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GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. |
| Volume: |
12 |
| Issue: |
5 |
| Pages: |
484-91 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
The Sld3 DNA replication regulator is required for loading and maintenance of Cdc45 on chromatin during DNA replication []. This entry represents the C-terminal domain of Sld3. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakajima R |
| Year: |
2002 |
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Mol Biol Cell |
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SpSld3 is required for loading and maintenance of SpCdc45 on chromatin in DNA replication in fission yeast. |
| Volume: |
13 |
| Issue: |
5 |
| Pages: |
1462-72 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, transgenic |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
333
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
110
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
131
 |
| Fragment?: |
false |
|
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•
•
•
•
|
| Publication |
| First Author: |
Tanaka T |
| Year: |
2011 |
| Journal: |
EMBO J |
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Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast. |
| Volume: |
30 |
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10 |
| Pages: |
2019-30 |
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•
•
•
•
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Altmann K |
| Year: |
2005 |
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Mol Biol Cell |
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Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. |
| Volume: |
16 |
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11 |
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5410-7 |
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•
•
•
•
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| Publication |
| First Author: |
Kumagai A |
| Year: |
2011 |
| Journal: |
J Cell Biol |
| Title: |
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. |
| Volume: |
193 |
| Issue: |
6 |
| Pages: |
995-1007 |
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•
•
•
•
|
| Publication |
| First Author: |
Saxena S |
| Year: |
2004 |
| Journal: |
Mol Cell |
| Title: |
A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
245-58 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Treslin, a TopBP1-interacting protein, is necessary for DNA replication in vertebrates []. Prior to the initiation of DNA replication, treslin associates with TopBP1 in a Cdk2-dependent manner []. The proteins then collaborate in the Cdk2-mediated loading of Cdc45 onto replication origins [].Treslin is also an important checkpoint regulator, and is required to prevent mitotic entry after treatment with ionizing radiation []. |
|
•
•
•
•
•
|