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Search results 201 to 300 out of 513 for Cdh16

0.037s
Type Details Score
Publication
First Author: Thedieck C
Year: 2005
Journal: Br J Cancer
Title: Expression of Ksp-cadherin during kidney development and in renal cell carcinoma.
Volume: 92
Issue: 11
Pages: 2010-7
Protein Domain
Type: Family
Description: Cadherins are transmembrane proteins that mediate cell-cell adhesion in animals []. Cadherin-16 (CDH16) or kidney-specific (Kps) cadherin was first described as a kidney-specific adhesion molecule []and thereafter also found expressed in the thyroid gland. CDH16 colocalises with CDH1/E-cadherin on the basolateral plasma membrane of thyrocytes, and might play a role during thyroid development [].
Allele
Name: transgene insertion 91, Peter Igarashi
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion F427, Dorien JM Peters
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Strain
Attribute String: mutant strain, congenic, transgenic
Publication
First Author: Qian CN
Year: 2009
Journal: Cancer Res
Title: Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models.
Volume: 69
Issue: 21
Pages: 8256-64
Genotype
Symbol: Tg(Cdh16-cre)91Igr/?
Background: either: (involves: C57BL/6 * ICR) or (involves: C57BL/6 * DBA/2 * ICR)
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Ikenberg K
Year: 2014
Journal: J Pathol
Title: KPNA2 is overexpressed in human and mouse endometrial cancers and promotes cellular proliferation.
Volume: 234
Issue: 2
Pages: 239-52
Publication
First Author: Wild PJ
Year: 2012
Journal: EMBO Mol Med
Title: p53 suppresses type II endometrial carcinomas in mice and governs endometrial tumour aggressiveness in humans.
Volume: 4
Issue: 8
Pages: 808-24
Publication
First Author: Zhou D
Year: 2019
Journal: FASEB J
Title: Early activation of fibroblasts is required for kidney repair and regeneration after injury.
Volume: 33
Issue: 11
Pages: 12576-12587
Publication
First Author: Meng XM
Year: 2012
Journal: J Pathol
Title: Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro.
Volume: 227
Issue: 2
Pages: 175-88
Publication
First Author: Meng XM
Year: 2012
Journal: Kidney Int
Title: Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro.
Volume: 81
Issue: 3
Pages: 266-79
Publication
First Author: Parajuli N
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: a possible trigger for autophagy and mitochondrial biogenesis?
Volume: 304
Issue: 3
Pages: F257-67
Publication
First Author: Parajuli N
Year: 2011
Journal: Free Radic Biol Med
Title: Generation and characterization of a novel kidney-specific manganese superoxide dismutase knockout mouse.
Volume: 51
Issue: 2
Pages: 406-16
Publication
First Author: Drusian L
Year: 2018
Journal: Cell Rep
Title: mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma.
Volume: 24
Issue: 5
Pages: 1093-1104.e6
Publication
First Author: Ma Y
Year: 2020
Journal: iScience
Title: SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
Volume: 23
Issue: 8
Pages: 101428
Publication
First Author: Lee HW
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion.
Volume: 296
Issue: 6
Pages: F1364-75
Publication
First Author: Bardella C
Year: 2011
Journal: J Pathol
Title: Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
Volume: 225
Issue: 1
Pages: 4-11
Publication
First Author: Kim HY
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Basolateral expression of the ammonia transporter family member Rh C glycoprotein in the mouse kidney.
Volume: 296
Issue: 3
Pages: F543-55
Publication
First Author: Jia M
Year: 2023
Journal: Mol Ther
Title: Targeting RNA oxidation by ISG20-mediated degradation is a potential therapeutic strategy for acute kidney injury.
Volume: 31
Issue: 10
Pages: 3034-3051
Publication
First Author: Zhu W
Year: 2024
Journal: Cell Mol Life Sci
Title: miR-148b-5p regulates hypercalciuria and calcium-containing nephrolithiasis.
Volume: 81
Issue: 1
Pages: 369
Publication
First Author: Jiang N
Year: 2022
Journal: FASEB J
Title: TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury.
Volume: 36
Issue: 4
Pages: e22228
Publication
First Author: Li J
Year: 2014
Journal: Kidney Int
Title: Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury.
Volume: 86
Issue: 1
Pages: 86-102
Publication
First Author: Choi SY
Year: 2013
Journal: J Am Soc Nephrol
Title: Cdc42 deficiency causes ciliary abnormalities and cystic kidneys.
Volume: 24
Issue: 9
Pages: 1435-50
Publication
First Author: Ji X
Year: 2023
Journal: iScience
Title: MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Volume: 26
Issue: 5
Pages: 106656
Publication  
First Author: Cui X
Year: 2022
Journal: Free Radic Biol Med
Title: GPR87 promotes renal tubulointerstitial fibrosis by accelerating glycolysis and mitochondrial injury.
Volume: 189
Pages: 58-70
Publication
First Author: Douma LG
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Kidney-specific KO of the circadian clock protein PER1 alters renal Na(+) handling, aldosterone levels, and kidney/adrenal gene expression.
Volume: 322
Issue: 4
Pages: F449-F459
Publication
First Author: Wang JN
Year: 2022
Journal: Sci Transl Med
Title: Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms.
Volume: 14
Issue: 640
Pages: eabk2709
Publication
First Author: Formica C
Year: 2019
Journal: J Mol Med (Berl)
Title: Characterisation of transcription factor profiles in polycystic kidney disease (PKD): identification and validation of STAT3 and RUNX1 in the injury/repair response and PKD progression.
Volume: 97
Issue: 12
Pages: 1643-1656
Publication
First Author: Streets AJ
Year: 2013
Journal: Hum Mol Genet
Title: Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.
Volume: 22
Issue: 10
Pages: 1924-39
Publication
First Author: Leonhard WN
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.
Volume: 300
Issue: 5
Pages: F1193-202
Publication
First Author: Streets AJ
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Parallel microarray profiling identifies ErbB4 as a determinant of cyst growth in ADPKD and a prognostic biomarker for disease progression.
Volume: 312
Issue: 4
Pages: F577-F588
Publication
First Author: Kanhai AA
Year: 2020
Journal: Sci Rep
Title: Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective.
Volume: 10
Issue: 1
Pages: 1672
Publication
First Author: Talbi K
Year: 2021
Journal: FASEB J
Title: The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.
Volume: 35
Issue: 10
Pages: e21897
Publication
First Author: Kramers BJ
Year: 2022
Journal: Clin J Am Soc Nephrol
Title: Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD: A Randomized Crossover Trial.
Volume: 17
Issue: 4
Pages: 507-517
Publication
First Author: Sánchez-López E
Year: 2019
Journal: Sci Rep
Title: Sheathless CE-MS based metabolic profiling of kidney tissue section samples from a mouse model of Polycystic Kidney Disease.
Volume: 9
Issue: 1
Pages: 806
Publication
First Author: Verschuren EHJ
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Polycystin-1 dysfunction impairs electrolyte and water handling in a renal precystic mouse model for ADPKD.
Volume: 315
Issue: 3
Pages: F537-F546
Publication
First Author: Yasinoglu SA
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Transcriptomic profiling of Polycystic Kidney Disease identifies paracrine factors in the early cyst microenvironment.
Volume: 1870
Issue: 2
Pages: 166987
Publication  
First Author: Leung JY
Year: 2017
Journal: Mol Cell Biol
Title: Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis.
Volume: 37
Issue: 12
Publication
First Author: Jiang Y
Year: 2019
Journal: Nat Commun
Title: MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.
Volume: 10
Issue: 1
Pages: 1515
Genotype
Symbol: Fh1/Fh1 Tg(Cdh16-cre)91Igr/?
Background: involves: 129X1/SvJ * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1 Tg(Cdh16-cre/ERT2)F427Djmp/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sod2/Sod2 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * C57BL/6CrSlc
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sod2/Sod2<+> Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * C57BL/6CrSlc
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prkcsh/Prkcsh Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prkcsh/Prkcsh Sec63/Sec63 Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sec63/Sec63 Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ano1/Ano1 Tg(Cdh16-cre)91Igr/?
Background: involves: 129S6/SvEvTac * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Trp53/Trp53 Tg(Cdh16-cre)91Igr/?
Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Cdh16-cre)91Igr/? Tg(EIF1AX-Lin28a)#Gqda/?
Background: involves: 129S4/SvJae * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Isg20/Isg20 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6N * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mrpl12/Mrpl12 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fh1/Fh1 Tg(Cdh16-cre)91Igr/?
Background: involves: 129X1/SvJ * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Koumarianou P
Year: 2017
Journal: J Cell Sci
Title: Pax8 controls thyroid follicular polarity through cadherin-16.
Volume: 130
Issue: 1
Pages: 219-231
Publication
First Author: Wodarczyk C
Year: 2010
Journal: PLoS One
Title: Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals.
Volume: 5
Issue: 9
Pages: e12719
Publication
First Author: Goodwin JE
Year: 2010
Journal: Biochem Biophys Res Commun
Title: The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension.
Volume: 394
Issue: 2
Pages: 266-71
Publication
First Author: Han SH
Year: 2016
Journal: J Am Soc Nephrol
Title: Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism.
Volume: 27
Issue: 2
Pages: 439-53
Publication
First Author: Li L
Year: 2010
Journal: Am J Pathol
Title: Autophagy is a component of epithelial cell fate in obstructive uropathy.
Volume: 176
Issue: 4
Pages: 1767-78
Publication
First Author: Li L
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Use of mouse hematopoietic stem and progenitor cells to treat acute kidney injury.
Volume: 302
Issue: 1
Pages: F9-F19
Publication
First Author: Ayuzawa N
Year: 2022
Journal: Sci Rep
Title: Rac1 deficiency impairs postnatal development of the renal papilla.
Volume: 12
Issue: 1
Pages: 20310
Publication
First Author: Zaidman NA
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion.
Volume: 117
Issue: 42
Pages: 26470-26481
Publication  
First Author: Fernandes MF
Year: 2024
Journal: Mol Metab
Title: Renal tubule-specific Atgl deletion links kidney lipid metabolism to glucagon-like peptide 1 and insulin secretion independent of renal inflammation or lipotoxicity.
Volume: 81
Pages: 101887
Publication
First Author: Meng XM
Year: 2010
Journal: J Am Soc Nephrol
Title: Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.
Volume: 21
Issue: 9
Pages: 1477-87
Publication  
First Author: Lin MH
Year: 2021
Journal: JCI Insight
Title: Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency.
Volume: 6
Issue: 20
Publication
First Author: Jain M
Year: 2019
Journal: Kidney Int
Title: Inactivation of Apoptosis Antagonizing Transcription Factor in tubular epithelial cells induces accumulation of DNA damage and nephronophthisis.
Volume: 95
Issue: 4
Pages: 846-858
Publication
First Author: Takiar V
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.
Volume: 108
Issue: 6
Pages: 2462-7
Publication
First Author: Liu W
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism.
Volume: 115
Issue: 7
Pages: E1475-E1484
Publication
First Author: Jun JH
Year: 2022
Journal: Exp Mol Med
Title: Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli.
Volume: 54
Issue: 2
Pages: 169-179
Publication
First Author: Ueda K
Year: 2017
Journal: Hypertension
Title: Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension.
Volume: 70
Issue: 1
Pages: 111-118
Publication
First Author: Cassina L
Year: 2020
Journal: FASEB J
Title: Increased mitochondrial fragmentation in polycystic kidney disease acts as a modifier of disease progression.
Volume: 34
Issue: 5
Pages: 6493-6507
Publication
First Author: Cabrita I
Year: 2020
Journal: Nat Commun
Title: Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.
Volume: 11
Issue: 1
Pages: 4320
Publication  
First Author: Podrini C
Year: 2018
Journal: Commun Biol
Title: Dissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways.
Volume: 1
Pages: 194
Publication      
First Author: Ishimoto Y
Year: 2017
Journal: Mol Cell Biol
Title: Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease.
Publication  
First Author: Ye S
Year: 2024
Journal: Redox Biol
Title: YAP1 preserves tubular mitochondrial quality control to mitigate diabetic kidney disease.
Volume: 78
Pages: 103435
Publication
First Author: Widjaja AA
Year: 2022
Journal: Nat Commun
Title: Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.
Volume: 13
Issue: 1
Pages: 7497
Publication
First Author: Charrin E
Year: 2023
Journal: Commun Biol
Title: Soluble Klotho protects against glomerular injury through regulation of ER stress response.
Volume: 6
Issue: 1
Pages: 208
Publication
First Author: Hasumi H
Year: 2017
Journal: Hum Mol Genet
Title: H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.
Volume: 26
Issue: 2
Pages: 354-366
Publication
First Author: Battini L
Year: 2008
Journal: Hum Mol Genet
Title: Loss of polycystin-1 causes centrosome amplification and genomic instability.
Volume: 17
Issue: 18
Pages: 2819-33
Publication
First Author: Wu M
Year: 2015
Journal: Oncotarget
Title: Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
Volume: 6
Issue: 32
Pages: 32761-73
Publication
First Author: Zhou X
Year: 2014
Journal: Hum Mol Genet
Title: SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.
Volume: 23
Issue: 6
Pages: 1644-55
Publication
First Author: Kim D
Year: 2007
Journal: J Am Soc Nephrol
Title: Pax transactivation-domain interacting protein is required for urine concentration and osmotolerance in collecting duct epithelia.
Volume: 18
Issue: 5
Pages: 1458-65
Publication  
First Author: Seo E
Year: 2016
Journal: Sci Rep
Title: The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis.
Volume: 6
Pages: 31931
Publication
First Author: Yang B
Year: 2008
Journal: J Am Soc Nephrol
Title: Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease.
Volume: 19
Issue: 7
Pages: 1300-10
Publication
First Author: Leonhard WN
Year: 2016
Journal: J Am Soc Nephrol
Title: Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.
Volume: 27
Issue: 12
Pages: 3589-3599
Publication
First Author: Happé H
Year: 2011
Journal: J Pathol
Title: Altered Hippo signalling in polycystic kidney disease.
Volume: 224
Issue: 1
Pages: 133-42
Publication  
First Author: Piazzon N
Year: 2015
Journal: J Transl Med
Title: Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.
Volume: 13
Pages: 103
Publication
First Author: Happé H
Year: 2009
Journal: Hum Mol Genet
Title: Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways.
Volume: 18
Issue: 14
Pages: 2532-42
Genotype
Symbol: Pkd1/Pkd1 Tg(Cdh16-cre/ERT2)F427Djmp/?
Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Flcn/Flcn Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Oxsr1/Oxsr1 Tg(Cdh16-cre)91Igr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Tg(Cdh16-cre)91Igr/?
Background: involves: 129X1/SvJ * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1<+> Prkcsh/Prkcsh Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1<+> Sec63/Sec63 Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cldn10/Cldn10 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kl/Kl Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fnip1/Fnip1 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fnip2/Fnip2 Tg(Cdh16-cre)91Igr/?
Background: involves: C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1 Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJae * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd1/Pkd1 Tg(Cdh16-cre)91Igr/?
Background: involves: 129 * 129S4/SvJae * C57BL/6 * ICR
Zygosity: cx
Has Mutant Allele: true