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Search results 201 to 300 out of 1952 for Cdkn2a

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Type Details Score
Publication
26965367 | J:235536
First Author: Barabino A
Year: 2016
Journal: Development
Title: Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.
Volume: 143
Issue: 9
Pages: 1571-84
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Publication
15175242 | J:90855
First Author: Aslanian A
Year: 2004
Journal: Genes Dev
Title: Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics.
Volume: 18
Issue: 12
Pages: 1413-22
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Publication
21209895 | J:168312
First Author: Rauch DA
Year: 2010
Journal: PLoS One
Title: The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.
Volume: 5
Issue: 12
Pages: e15755
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Publication
14673154 | J:87594
First Author: O'Leary KA
Year: 2004
Journal: Mol Cell Biol
Title: Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues.
Volume: 24
Issue: 1
Pages: 186-91
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Publication
15589172 | J:94683
First Author: Iwama A
Year: 2004
Journal: Immunity
Title: Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1.
Volume: 21
Issue: 6
Pages: 843-51
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Publication
19690330 | J:260259
First Author: Chen Z
Year: 2009
Journal: Sci Signal
Title: Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
Volume: 2
Issue: 84
Pages: ra44
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Publication
20197621 | J:158734
First Author: Alimonti A
Year: 2010
Journal: J Clin Invest
Title: A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Volume: 120
Issue: 3
Pages: 681-93
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Publication
28263978 | J:243369
First Author: Wang GY
Year: 2017
Journal: Oncogene
Title: Differing tumor-suppressor functions of Arf and p53 in murine basal cell carcinoma initiation and progression.
Volume: 36
Issue: 26
Pages: 3772-3780
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Publication
25622904 | J:244951
First Author: Tan M
Year: 2015
Journal: Neoplasia
Title: Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Volume: 17
Issue: 1
Pages: 114-23
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Publication
28949402 | J:283471
First Author: Zhao L
Year: 2018
Journal: Mol Carcinog
Title: Gain of function in the mouse model of a recurrent mutation p53N236S promotes the formation of double minute chromosomes and the oncogenic potential of p19ARF.
Volume: 57
Issue: 2
Pages: 147-158
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Publication
35150661 | J:323002
     
First Author: Lazar I
Year: 2022
Journal: J Invest Dermatol
Title: Adipocyte Extracellular Vesicles Decrease p16INK4A in Melanoma: An Additional Link between Obesity and Cancer.
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Publication
19398955 | J:151455
First Author: Goel VK
Year: 2009
Journal: Oncogene
Title: Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice.
Volume: 28
Issue: 23
Pages: 2289-98
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Publication
28577303 | J:253445
First Author: Jackson JT
Year: 2017
Journal: Stem Cells
Title: Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a.
Volume: 35
Issue: 8
Pages: 1948-1957
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Publication
22860046 | J:189678
First Author: Winkeler CL
Year: 2012
Journal: PLoS One
Title: Cathepsin K-Cre causes unexpected germline deletion of genes in mice.
Volume: 7
Issue: 7
Pages: e42005
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Publication
22048312 | J:178299
First Author: Baker DJ
Year: 2011
Journal: Nature
Title: Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Volume: 479
Issue: 7372
Pages: 232-6
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Publication
21804542 | J:241062
First Author: Sasaki M
Year: 2011
Journal: Nat Med
Title: Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.
Volume: 17
Issue: 8
Pages: 944-51
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Publication
17728759 | J:125164
First Author: Gorrini C
Year: 2007
Journal: Nature
Title: Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
Volume: 448
Issue: 7157
Pages: 1063-7
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Publication
16222716 | J:102855
First Author: Jerome-Majewska LA
Year: 2005
Journal: Dev Dyn
Title: Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway.
Volume: 234
Issue: 4
Pages: 922-33
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Publication
11212243 | J:67452
First Author: Wetmore C
Year: 2001
Journal: Cancer Res
Title: Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.
Volume: 61
Issue: 2
Pages: 513-6
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Publication
12082524 | J:126187
First Author: Palmero I
Year: 2002
Journal: Oncogene
Title: Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2.
Volume: 21
Issue: 19
Pages: 2939-47
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Publication
25694388 | J:224180
First Author: Kitajima S
Year: 2015
Journal: Stem Cells
Title: Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts.
Volume: 33
Issue: 5
Pages: 1657-69
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Publication
18076574 | J:138263
First Author: Miki J
Year: 2007
Journal: Genes Cells
Title: Polycomb complexes regulate cellular senescence by repression of ARF in cooperation with E2F3.
Volume: 12
Issue: 12
Pages: 1371-82
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Publication
16904610 | J:112704
First Author: Finch A
Year: 2006
Journal: Cancer Cell
Title: Bcl-xL gain of function and p19 ARF loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms.
Volume: 10
Issue: 2
Pages: 113-20
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Publication
16707443 | J:109060
First Author: Shakhova O
Year: 2006
Journal: Cancer Res
Title: Lack of Rb and p53 delays cerebellar development and predisposes to large cell anaplastic medulloblastoma through amplification of N-Myc and Ptch2.
Volume: 66
Issue: 10
Pages: 5190-200
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Publication
19465598 | J:149526
First Author: Freeman-Anderson NE
Year: 2009
Journal: Development
Title: Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development.
Volume: 136
Issue: 12
Pages: 2081-9
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Publication
18636078 | J:154352
First Author: Ewing SJ
Year: 2008
Journal: Cell Death Differ
Title: C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf).
Volume: 15
Issue: 11
Pages: 1734-44
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Publication
21747916 | J:174526
First Author: Pan W
Year: 2011
Journal: PLoS One
Title: The in vivo role of the RP-Mdm2-p53 pathway in signaling oncogenic stress induced by pRb inactivation and Ras overexpression.
Volume: 6
Issue: 6
Pages: e21625
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Publication
28049658 | J:239161
First Author: Guo C
Year: 2017
Journal: Development
Title: Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.
Volume: 144
Issue: 3
Pages: 400-408
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Publication
32090320 | J:292618
First Author: Jackson JT
Year: 2020
Journal: Eur J Immunol
Title: Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a.
Volume: 50
Issue: 7
Pages: 959-971
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Publication
27730210 | J:259440
First Author: Rossi A
Year: 2016
Journal: Sci Adv
Title: Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.
Volume: 2
Issue: 10
Pages: e1600972
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Publication
23772040 | J:209557
First Author: Zhao Y
Year: 2013
Journal: J Leukoc Biol
Title: IL-4 induces a suppressive IL-10-producing CD8+ T cell population via a Cdkn2a-dependent mechanism.
Volume: 94
Issue: 6
Pages: 1103-12
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Publication
27585866 | J:237929
First Author: Chiacchiera F
Year: 2016
Journal: EMBO J
Title: PRC2 preserves intestinal progenitors and restricts secretory lineage commitment.
Volume: 35
Issue: 21
Pages: 2301-2314
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Publication
25644707 | J:221064
First Author: de Andrea CE
Year: 2015
Journal: J Pathol
Title: Cell cycle deregulation and mosaic loss of Ext1 drive peripheral chondrosarcomagenesis in the mouse and reveal an intrinsic cilia deficiency.
Volume: 236
Issue: 2
Pages: 210-8
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Publication
34090875 | J:343889
First Author: Duong P
Year: 2021
Journal: J Biol Chem
Title: H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve.
Volume: 297
Issue: 1
Pages: 100852
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Publication
23665474 | J:199589
First Author: Zheng Y
Year: 2013
Journal: Dev Biol
Title: A distant, cis-acting enhancer drives induction of Arf by Tgfβ in the developing eye.
Volume: 380
Issue: 1
Pages: 49-57
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Publication
18957199 | J:144068
First Author: Nishino J
Year: 2008
Journal: Cell
Title: Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression.
Volume: 135
Issue: 2
Pages: 227-39
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Publication
29706499 | J:349146
First Author: Le O
Year: 2018
Journal: Stem Cell Reports
Title: INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.
Volume: 10
Issue: 6
Pages: 1721-1733
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Publication
36167470 | J:333068
First Author: Burgess RJ
Year: 2022
Journal: Genes Dev
Title: Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells.
Volume: 36
Issue: 15-16
Pages: 887-900
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Publication
17438529 | J:125535
First Author: Tchougounova E
Year: 2007
Journal: Oncogene
Title: Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma.
Volume: 26
Issue: 43
Pages: 6289-96
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Publication
28652370 | J:244260
First Author: van Oosterwijk JG
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice.
Volume: 114
Issue: 28
Pages: 7420-7425
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Publication
19401450 | J:148496
First Author: Rahrmann EP
Year: 2009
Journal: Cancer Res
Title: Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon-based somatic mutagenesis screen.
Volume: 69
Issue: 10
Pages: 4388-97
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Publication
25253740 | J:219681
First Author: Sinha VC
Year: 2015
Journal: Mol Cancer Res
Title: A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis.
Volume: 13
Issue: 2
Pages: 231-8
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Publication
23825691 | J:203738
First Author: Mullins CD
Year: 2013
Journal: PLoS One
Title: Germinal center B-cells resist transformation by Kras independently of tumor suppressor Arf.
Volume: 8
Issue: 6
Pages: e67941
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Publication
37267953 | J:338213
First Author: Haston S
Year: 2023
Journal: Cancer Cell
Title: Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Volume: 41
Issue: 7
Pages: 1242-1260.e6
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Publication
28522693 | J:245737
First Author: Cordero FJ
Year: 2017
Journal: Mol Cancer Res
Title: Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.
Volume: 15
Issue: 9
Pages: 1243-1254
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Publication
32820269 | J:303978
First Author: Aoyama K
Year: 2021
Journal: Leukemia
Title: PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.
Volume: 35
Issue: 4
Pages: 1156-1165
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Publication
19339268 | J:147341
First Author: Nishijo K
Year: 2009
Journal: Cancer Res
Title: Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma.
Volume: 69
Issue: 7
Pages: 2902-11
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Publication
28475592 | J:247139
First Author: Ma L
Year: 2017
Journal: PLoS One
Title: LSL-KrasG12D; LSL-Trp53R172H/+; Ink4flox/+; Ptf1/p48-Cre mice are an applicable model for locally invasive and metastatic pancreatic cancer.
Volume: 12
Issue: 5
Pages: e0176844
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Publication
30093562 | J:265555
First Author: Oristian KM
Year: 2018
Journal: Cancer Res
Title: Loss of MST/Hippo Signaling in a Genetically Engineered Mouse Model of Fusion-Positive Rhabdomyosarcoma Accelerates Tumorigenesis.
Volume: 78
Issue: 19
Pages: 5513-5520
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Publication
36445254 | J:333622
First Author: Ko A
Year: 2023
Journal: Cancer Discov
Title: LZTR1 Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL.
Volume: 13
Issue: 3
Pages: 702-723
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Publication
18583527 | J:139874
First Author: Bailey SL
Year: 2008
Journal: Mol Cancer Res
Title: Tumor suppression by p53 in the absence of Atm.
Volume: 6
Issue: 7
Pages: 1185-92
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Publication
23955081 | J:204354
First Author: Maynard MA
Year: 2014
Journal: Oncogene
Title: Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer.
Volume: 33
Issue: 28
Pages: 3742-7
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Publication
18697930 | J:139699
First Author: Dovey JS
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.
Volume: 105
Issue: 33
Pages: 11857-62
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Publication
16205640 | J:105657
First Author: Russell JL
Year: 2006
Journal: Oncogene
Title: E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway.
Volume: 25
Issue: 6
Pages: 867-76
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Publication
27356744 | J:264783
First Author: Xie Y
Year: 2016
Journal: Oncotarget
Title: MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo.
Volume: 7
Issue: 30
Pages: 47609-47619
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Publication
29185453 | J:255776
First Author: Xie Y
Year: 2017
Journal: Sci Rep
Title: Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots.
Volume: 7
Issue: 1
Pages: 16577
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Publication
24225533 | J:223503
 
First Author: Annunziata I
Year: 2013
Journal: Nat Commun
Title: Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis.
Volume: 4
Pages: 2734
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Publication
20237562 | J:158121
First Author: Lin HK
Year: 2010
Journal: Nature
Title: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
Volume: 464
Issue: 7287
Pages: 374-9
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Publication
21427293 | J:173263
First Author: Treanor LM
Year: 2011
Journal: Blood
Title: Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
Volume: 117
Issue: 20
Pages: 5453-62
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Publication
15878778 | J:100600
First Author: Sharpless NE
Year: 2005
Journal: Mutat Res
Title: INK4a/ARF: a multifunctional tumor suppressor locus.
Volume: 576
Issue: 1-2
Pages: 22-38
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Publication
19345325 | J:147436
First Author: Shamma A
Year: 2009
Journal: Cancer Cell
Title: Rb Regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation.
Volume: 15
Issue: 4
Pages: 255-69
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Publication
19219070 | J:147585
First Author: Tchougounova E
Year: 2009
Journal: Oncogene
Title: Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence.
Volume: 28
Issue: 12
Pages: 1537-48
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Publication
33004350 | J:299185
First Author: Koss B
Year: 2020
Journal: Cancer Res
Title: Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.
Volume: 80
Issue: 21
Pages: 4707-4719
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Publication
27728804 | J:236714
First Author: Eggert T
Year: 2016
Journal: Cancer Cell
Title: Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
Volume: 30
Issue: 4
Pages: 533-547
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Publication
16015333 | J:99991
First Author: Collier LS
Year: 2005
Journal: Nature
Title: Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse.
Volume: 436
Issue: 7048
Pages: 272-6
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Publication
30679733 | J:275921
First Author: El Hajjar J
Year: 2019
Journal: Sci Rep
Title: Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.
Volume: 9
Issue: 1
Pages: 594
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Publication
17158963 | J:120284
First Author: Shreeram S
Year: 2006
Journal: J Exp Med
Title: Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
Volume: 203
Issue: 13
Pages: 2793-9
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Publication
17562874 | J:125810
First Author: Reimann M
Year: 2007
Journal: Blood
Title: The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Volume: 110
Issue: 8
Pages: 2996-3004
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Publication
20068150 | J:156751
First Author: Kool J
Year: 2010
Journal: Cancer Res
Title: Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.
Volume: 70
Issue: 2
Pages: 520-31
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Publication
20193684 | J:267252
First Author: Mair M
Year: 2010
Journal: Gastroenterology
Title: Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Volume: 138
Issue: 7
Pages: 2499-508
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Publication
28115362 | J:239606
First Author: Sreedharan S
Year: 2017
Journal: Cancer Res
Title: Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.
Volume: 77
Issue: 3
Pages: 802-812
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Publication
24910389 | J:316436
First Author: Xie Y
Year: 2014
Journal: Mol Oncol
Title: Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis.
Volume: 8
Issue: 7
Pages: 1355-64
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Publication
27213815 | J:239769
First Author: Dauch D
Year: 2016
Journal: Nat Med
Title: A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Volume: 22
Issue: 7
Pages: 744-53
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Publication
23881917 | J:202362
First Author: Koss B
Year: 2013
Journal: Blood
Title: Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia.
Volume: 122
Issue: 9
Pages: 1587-98
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Publication
12589020 | J:82399
First Author: Voncken JW
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition.
Volume: 100
Issue: 5
Pages: 2468-73
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Publication
33300045 | J:354474
First Author: Ross JL
Year: 2021
Journal: Brain
Title: Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Volume: 144
Issue: 1
Pages: 53-69
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Protein Coding Gene
MGI:1261797 | Cdkn2aipnl
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16103190 | J:101623
First Author: Balsitis S
Year: 2005
Journal: J Virol
Title: Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.
Volume: 79
Issue: 17
Pages: 11392-402
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Publication
26982726 | J:232714
First Author: Liu Y
Year: 2016
Journal: Nature
Title: Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.
Volume: 531
Issue: 7595
Pages: 471-475
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Publication
27183622 | J:349140
First Author: Manlove LS
Year: 2016
Journal: J Immunol
Title: Heterologous Vaccination and Checkpoint Blockade Synergize To Induce Antileukemia Immunity.
Volume: 196
Issue: 11
Pages: 4793-804
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Publication
28082400 | J:239380
First Author: Owczarek TB
Year: 2017
Journal: Cancer Res
Title: ARF Confers a Context-Dependent Response to Chemotherapy in Muscle-Invasive Bladder Cancer.
Volume: 77
Issue: 4
Pages: 1035-1046
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Publication
20388773 | J:159371
First Author: Bender AM
Year: 2010
Journal: Cancer Res
Title: Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas.
Volume: 70
Issue: 9
Pages: 3557-65
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Publication
19339492 | J:147752
First Author: Gromley A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice.
Volume: 106
Issue: 15
Pages: 6285-90
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Publication
37267954 | J:337912
First Author: Prieto LI
Year: 2023
Journal: Cancer Cell
Title: Senescent alveolar macrophages promote early-stage lung tumorigenesis.
Volume: 41
Issue: 7
Pages: 1261-1275.e6
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Publication
26238783 | J:225884
First Author: Remy E
Year: 2015
Journal: Cancer Res
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