|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 278 out of 278 for Chad

<< First    < Previous  |  Next >    Last >>
0.023s

Categories

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_08
Specimen Label: euxassay_006850_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_09
Specimen Label: euxassay_006850_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_10
Specimen Label: euxassay_006850_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_11
Specimen Label: euxassay_006850_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_12
Specimen Label: euxassay_006850_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_13
Specimen Label: euxassay_006850_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_14
Specimen Label: euxassay_006850_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_15
Specimen Label: euxassay_006850_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_16
Specimen Label: euxassay_006850_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_17
Specimen Label: euxassay_006850_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_18
Specimen Label: euxassay_006850_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_19
Specimen Label: euxassay_006850_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_20
Specimen Label: euxassay_006850_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_21
Specimen Label: euxassay_006850_21
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_22
Specimen Label: euxassay_006850_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_23
Specimen Label: euxassay_006850_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_24
Specimen Label: euxassay_006850_24
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6457422
Assay Type: RNA in situ
Annotation Date: 2020-12-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757723
Stage: TS23
Assay Id: MGI:6488551
Age: embryonic day 15.5
Specimen Label: S1 Table B18
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_03
Specimen Label: euxassay_006850_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_04
Specimen Label: euxassay_006850_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_05
Specimen Label: euxassay_006850_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_23
Specimen Label: euxassay_006850_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_24
Specimen Label: euxassay_006850_24
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1912323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_05
Specimen Label: euxassay_006850_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1912323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823832
Age: embryonic day 14.5
Image: euxassay_006850_24
Specimen Label: euxassay_006850_24
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1555799
Assay Type: RNA in situ
Annotation Date: 2020-04-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6406522
Age: embryonic day 14.5
Image: 4B
Specimen Label: 4B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6169705
Assay Type: RNA in situ
Annotation Date: 2020-04-28
Strength: Present
Sex: Male
Emaps: EMAPS:3798428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6406545
Age: postnatal day 4
Image: 4F
Note: Expressed in the soft tissues surrounding spinal cord.
Specimen Label: 4F
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
10542325 | J:58267
First Author: Cohen DE
Year: 1999
Journal: Biochim Biophys Acta
Title: Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein.
Volume: 1447
Issue: 2-3
Pages: 265-70
•
•
•
•
•
Publication
9838122 | J:48003
First Author: Lin L
Year: 1998
Journal: Biochim Biophys Acta
Title: cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus.
Volume: 1443
Issue: 1-2
Pages: 211-6
•
•
•
•
•
Publication
10087300 | J:54121
First Author: Nasir J
Year: 1999
Journal: Mamm Genome
Title: Chromosomal localization of the Huntingtin associated protein (HAP-1) gene in mouse and humans with radiation hybrid and interspecific backcross mapping.
Volume: 10
Issue: 4
Pages: 397-8
•
•
•
•
•
Publication
9465299 | J:42830
First Author: Landgren C
Year: 1998
Journal: Genomics
Title: The mouse chondroadherin gene: characterization and chromosomal localization.
Volume: 47
Issue: 1
Pages: 84-91
•
•
•
•
•
Publication
26077908 | J:223752
First Author: Cai T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene.
Volume: 112
Issue: 26
Pages: 8064-9
•
•
•
•
•
Publication
12796502 | J:85206
First Author: Ross MD
Year: 2003
Journal: J Biol Chem
Title: Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy.
Volume: 278
Issue: 35
Pages: 33248-55
•
•
•
•
•
Publication
11711534 | J:73962
First Author: Seykora JT
Year: 2002
Journal: J Biol Chem
Title: 'Srcasm: a novel Src activating and signaling molecule.
Volume: 277
Issue: 4
Pages: 2812-22
•
•
•
•
•
Publication
10433968 | J:56924
First Author: Sagane K
Year: 1999
Journal: Gene
Title: Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23.
Volume: 236
Issue: 1
Pages: 79-86
•
•
•
•
•
Publication
15215744 | J:91136
 
First Author: Tasheva ES
Year: 2004
Journal: Mol Vis
Title: Differentially expressed genes in the lens of mimecan-null mice.
Volume: 10
Pages: 403-16
•
•
•
•
•
Publication
9832566 | J:51376
First Author: Aszódi A
Year: 1998
Journal: J Cell Biol
Title: Collagen II is essential for the removal of the notochord and the formation of intervertebral discs.
Volume: 143
Issue: 5
Pages: 1399-412
•
•
•
•
•
Publication
35112129 | J:321577
 
First Author: Yin W
Year: 2022
Journal: Development
Title: An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
Volume: 149
Issue: 3
•
•
•
•
•
Publication
33153107 | J:298990
 
First Author: Sah RK
Year: 2020
Journal: Int J Mol Sci
Title: Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.
Volume: 21
Issue: 21
•
•
•
•
•
Publication
25826454 | J:229257
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
•
•
•
•
•
Publication
16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
•
•
•
•
•
Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
32931734 | J:335892
First Author: Hassan AO
Year: 2020
Journal: Cell
Title: A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.
Volume: 183
Issue: 1
Pages: 169-184.e13
•
•
•
•
•
Allele
Tg(ACTA1-Scd1)282Ptn | MGI:5496824
Name: transgene insertion 282, Chad Paton
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Strain
MGI:5496828 | B6.Cg-Tg(ACTA1-Scd1)282Ptn/J
Attribute String: congenic, mutant strain, transgenic
•
•
•
•
•
Allele
Gpr146<em1Ccwn> | MGI:6460322
Name: G protein-coupled receptor 146; endonuclease-mediated mutation 1, Chad A Cowan
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Gpr146<em2Ccwn> | MGI:6460323
Name: G protein-coupled receptor 146; endonuclease-mediated mutation 2, Chad A Cowan
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Ssbp3<em1Cshu> | MGI:7525283
Name: single-stranded DNA binding protein 3; endonuclease-mediated mutation 1, Chad S Hunter
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
•
•
•
•
•
Publication
12456267 | -
First Author: Iyer LM
Year: 2002
Journal: BMC Genomics
Title: The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates.
Volume: 3
Issue: 1
Pages: 33
•
•
•
•
•
Publication
37536498 | J:339475
 
First Author: Toren E
Year: 2023
Journal: Mol Metab
Title: The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity.
Volume: 76
Pages: 101785
•
•
•
•
•
Allele
Dp(11Mpo-Chad)18Brd | MGI:3766572
 
Name: duplication, Chr 11, Bradley 18; duplication, Chr 11, Allan Bradley 18
Allele Type: Targeted
•
•
•
•
•
Allele
Del(11Mpo-Chad)18Brd | MGI:3766573
Name: deletion, Chr 11, Bradley 18; deletion, Chr 11, Allan Bradley 18
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Allele
Del(11Chad-Hoxb1)19Brd | MGI:3766574
Name: deletion, Chr 11, Bradley 19; deletion, Chr 11, Allan Bradley 19
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Publication
31778654 | J:289767
First Author: Yu H
Year: 2019
Journal: Cell
Title: GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.
Volume: 179
Issue: 6
Pages: 1276-1288.e14
•
•
•
•
•
Genotype
Genotype
Symbol: Del(11Chad-Hoxb1)19Brd/+
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Del(11Mpo-Chad)18Brd/Del(11Mpo-Chad)18Brd
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Del(11Mpo-Chad)18Brd/+
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Dp(11Mpo-Chad)18Brd/Dp(11Mpo-Chad)18Brd
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein Domain
IPR012069 | UPF_CYTH/CHAD/HD-like
Type: Family
Description: This group includes uncharacterised proteins from Methanosarcina spp. with CYTH and CHAD domains, and a central HD-like domain.CYTH domain proteins may play a central role in the interface between nucleotide and polyphosphate metabolism []. Based on the conservation of catalytic residues, CYTH domains are likely to chelate two divalent cations and exhibit a reaction mechanism that is dependent on two metal ions, analogous to nucleotide cyclases, polymerases, and certain phosphoesterases []. It has also been suggested that the experimentally characterised members of the CYTH domain superfamily, namely, adenylyl cyclase and thiamine triphosphatase, are secondary derivatives of proteins that performed an ancient role in polyphosphate and nucleotide metabolism [].The C-terminal CHAD domain () is an α-helical domain that is found fused to the CYTH domain or is encoded by genes occurring in the same operon as those encoding CYTH domains. Therefore, it is predicted to be functionally associated with CYTH adenylate cyclases []. While there is no experimental evidence as to the function of the CHAD domain, and no clear functional prediction can be made for it, the conserved histidines and other charged residues could form a strongly polar surface that could either participate in metal chelation, or act as phosphoacceptors [].Apart from these two domains, members of this group have a unique central domain. It is distantly related to the HD-type metal dependent phosphohydrolase domain (), but there is no indication as to its function.
•
•
•
•
•
Strain
MGI:4820537 | B6;129S7-Del(11Mpo-Chad)18Brd Dp(11Mpo-Chad)18Brd/Mmucd
Attribute String: deletion, duplication, mutant stock, targeted mutation
•
•
•
•
•
Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom