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Search results 201 to 223 out of 223 for Chrdl1

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Type Details Score
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Chrdl1<em1Smoc> | MGI:7288970
Name: chordin-like 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428425 | C57BL/6JSmoc-Chrdl1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Gene
4053 | LTBP2
Type: gene
Organism: human
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DO Term
DOID:0060305 | megalocornea
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Protein Domain
IPR045716 | CHRDL_1/2_C
Type: Domain
Description: This is the C-terminal domain of Chordin-like proteins 1 and 2 (CHRDL1/2). CHRDL1 antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors []. CHRDL2 inhibit bone morphogenetic proteins (BMPs) activity by blocking their interaction with their receptor []. CHRDL2 may play a role during myoblast and osteoblast differentiation and maturation []. It's worth noting that there are different results regarding its binding partners; according to [], CHRDL2 interacts with INHBA but not BMP2, BMP4 and BMP6.
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Publication
18587495 | -
 
First Author: Kane R
Year: 2008
Journal: Mol Vis
Title: Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
Volume: 14
Pages: 1138-48
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Publication
15094188 | -
 
First Author: Oren A
Year: 2004
Journal: Gene
Title: hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
Volume: 331
Pages: 17-31
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Protein
F6WCT1
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: true
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Protein Domain
IPR045717 | CHRDL1/2
Type: Family
Description: This entry includes chordin-like protein 1/2 (CHRDL1/2). CHRDL1 antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors []. CHRDL2 inhibit bone morphogenetic proteins (BMPs) activity by blocking their interaction with their receptor []. CHRDL2 may play a role during myoblast and osteoblast differentiation and maturation []. It's worth noting that there are different results regarding its binding partners; according to [], CHRDL2 interacts with INHBA but not BMP2, BMP4 and BMP6.Bone is composed of an organic matrix that is principally collagenous and is mineralised with inorganic crystals of hydroxyapatite. Demineralisation of the bone results in a demineralised bone matrix []. In 1965, Urist M.R demonstrates the decalcified bone matrix (DBM) can induce ectopic bone/cartilage formation []. The morphogens in DBM that induce such skeletogenesis were named as bone morphogenetic proteins (BMPs) []. Since then, more than 20 members of BMPs have been identified. BMPs are potent effectors in almost all crucial biological events, such development, maintenance and regeneration of organs/tissues [].
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Protein
Q920C1
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Protein
Q8VEA6
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
A0A0B4J1E8
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
D3YV59
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
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Publication
22209847 | -
First Author: Ohyama Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Modulation of matrix mineralization by Vwc2-like protein and its novel splicing isoforms.
Volume: 418
Issue: 1
Pages: 12-6
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Publication
5319761 | -
First Author: Urist MR
Year: 1965
Journal: Science
Title: Bone: formation by autoinduction.
Volume: 150
Issue: 3698
Pages: 893-9
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Publication
19900831 | -
First Author: Reddi AH
Year: 2009
Journal: Cytokine Growth Factor Rev
Title: Bone morphogenetic proteins (BMPs): from morphogens to metabologens.
Volume: 20
Issue: 5-6
Pages: 341-2
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Protein
Q3TP73
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
A0A140LIV5
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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