Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 254 out of 254 for Cnot4

<< First < Previous | Next > Last >>

0.028s

Type

Details

Score

Publication

- | J:23000

First Author:	MGD Nomenclature Committee
Year:	1995

Title:	Nomenclature Committee Use

•

Publication

14610273 | J:86696

First Author:	Zambrowicz BP
Year:	2003
Journal:	Proc Natl Acad Sci U S A
Title:	Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume:	100
Issue:	24
Pages:	14109-14

•

Publication

21677750 | J:173534

First Author:	Skarnes WC
Year:	2011
Journal:	Nature
Title:	A conditional knockout resource for the genome-wide study of mouse gene function.
Volume:	474
Issue:	7351
Pages:	337-42

•

Publication

- | J:141210

First Author:	Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year:	2008
Journal:	Database Download
Title:	Mouse Gene Trap Data Load from dbGSS

•

Publication

- | J:342587

First Author:	AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year:	2011

Title:	Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

•

Publication

- | J:60000

First Author:	UniProt-GOA
Year:	2012

Title:	Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

•

Publication

- | J:68900

First Author:	The Jackson Laboratory Mouse Radiation Hybrid Database
Year:	2004
Journal:	Database Release
Title:	Mouse T31 Radiation Hybrid Data Load

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

•

Publication

- | J:164563

First Author:	The Gene Ontology Consortium
Year:	2010

Title:	Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

•

Publication

- | J:75000

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2002

Title:	Mouse Genome Informatics Computational Sequence to Gene Associations

•

Publication

- | J:157972

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2010
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).

•

Publication

- | J:161428

First Author:	Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year:	2010

Title:	Annotation inferences using phylogenetic trees

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

HT Experiment

GSE158471 | The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis


Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	GEO

•

Allele

Cnot4<em1Smoc> | MGI:7289056

Name:	CCR4-NOT transcription complex, subunit 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Interaction Experiment

Sun HY (2015)

Description:

Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome.

•

Publication

25933433 | -

First Author:	Sun HY
Year:	2015
Journal:	PLoS One
Title:	Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome.
Volume:	10
Issue:	5
Pages:	e0125599

•

Strain

MGI:6475023 | C57BL/6JSmoc-Cnot4<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

•

Protein

Q8BT14

Organism:	Mus musculus/domesticus
Length:	575
Fragment?:	false

•

Protein

Q8BT14-2

Organism:	Mus musculus/domesticus
Length:	572
Fragment?:	false

•

Protein

Q8BT14-3

Organism:	Mus musculus/domesticus
Length:	713
Fragment?:	false

•

Publication

12771185 | -

First Author:	Morel AP
Year:	2003
Journal:	J Cell Sci
Title:	BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms.
Volume:	116
Issue:	Pt 14
Pages:	2929-36

•

Protein Domain

IPR027212 | Cnot8

Type:	Family
Description:	CNOT8 is a subunit of the CCR4-NOT core complex that contains CCRN4L, CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4 and CNOT8. The CCR4-NOT complex functions as general transcription regulation complex [].

•

Publication

39113018 | J:354580

First Author:	Zhu J
Year:	2024
Journal:	Respir Res
Title:	TNKS1BP1 mediates AECII senescence and radiation induced lung injury through suppressing EEF2 degradation.
Volume:	25
Issue:	1
Pages:	299

•

Protein Domain

IPR039780 | Mot2

Type:

Family

Description:

NOT4, also known as CNOT4 or MOT2, is a component of the CCR4-NOT complex, a global negative regulator of RNA polymerase II transcription []. It associates with polysomes and contributes to the negative regulation of protein synthesis [, , , , , , , ]. NOT4 functions as an E3 ubiquitin-protein ligase that interacts with a specific E2, Ubc4/5 in yeast, and the orthologue UbcH5B in humans, and ubiquitinates a wide range of substrates, including ribosome-associated factors []. Thus, it plays a role in cotranslational quality control (QC) through ribosome-associated ubiquitination and degradation of aberrant peptides. NOT4 contains a C4C4-type RING finger motif, whose overall folding is similar to that of the C3HC4-type RING-HC finger, a central RNA recognition motif (RRM), and a C-terminal domain predicted to be unstructured [].

•

Protein

A2AFQ7

Organism:	Mus musculus/domesticus
Length:	75
Fragment?:	true

•

Publication

11087754 | -

First Author:	Hanzawa H
Year:	2001
Journal:	J Biol Chem
Title:	The structure of the C4C4 ring finger of human NOT4 reveals features distinct from those of C3HC4 RING fingers.
Volume:	276
Issue:	13
Pages:	10185-90

•

Publication

11823428 | -

First Author:	Albert TK
Year:	2002
Journal:	EMBO J
Title:	Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex.
Volume:	21
Issue:	3
Pages:	355-64

•

Publication

22159038 | -

First Author:	Grönholm J
Year:	2012
Journal:	FASEB J
Title:	Not4 enhances JAK/STAT pathway-dependent gene expression in Drosophila and in human cells.
Volume:	26
Issue:	3
Pages:	1239-50

•

Publication

25971775 | -

First Author:	Preissler S
Year:	2015
Journal:	EMBO J
Title:	Not4-dependent translational repression is important for cellular protein homeostasis in yeast.
Volume:	34
Issue:	14
Pages:	1905-24

•

Publication

26279681 | -

First Author:	Cotobal C
Year:	2015
Journal:	Epigenetics Chromatin
Title:	Role of Ccr4-Not complex in heterochromatin formation at meiotic genes and subtelomeres in fission yeast.
Volume:	8

Pages:	28

•

Publication

25914052 | -

First Author:	Bhaskar V
Year:	2015
Journal:	Structure
Title:	Architecture of the ubiquitylation module of the yeast Ccr4-Not complex.
Volume:	23
Issue:	5
Pages:	921-928

•

Publication

24904641 | -

First Author:	Panasenko OO
Year:	2014
Journal:	Front Genet
Title:	The role of the E3 ligase Not4 in cotranslational quality control.
Volume:	5

Pages:	141

•

Publication

24465968 | -

First Author:	Halter D
Year:	2014
Journal:	PLoS One
Title:	The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control.
Volume:	9
Issue:	1
Pages:	e86218

•

Protein

Q9D8X5

Organism:	Mus musculus/domesticus
Length:	292
Fragment?:	false

•

Publication

15062086 | -

First Author:	Dominguez C
Year:	2004
Journal:	Structure
Title:	Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches.
Volume:	12
Issue:	4
Pages:	633-44

•

Publication

17525332 | -

First Author:	Matsuoka S
Year:	2007
Journal:	Science
Title:	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Volume:	316
Issue:	5828
Pages:	1160-6

•

Publication

10637334 | -

First Author:	Albert TK
Year:	2000
Journal:	Nucleic Acids Res
Title:	Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.
Volume:	28
Issue:	3
Pages:	809-17

•

Protein

E9QA19

Organism:	Mus musculus/domesticus
Length:	642
Fragment?:	false

•

Protein

Q3TMD4

Organism:	Mus musculus/domesticus
Length:	572
Fragment?:	false

•

Protein

A0A0R4J1K1

Organism:	Mus musculus/domesticus
Length:	710
Fragment?:	false

•

Publication

24129315 | J:306378

First Author:	Guo A
Year:	2014
Journal:	Mol Cell Proteomics
Title:	Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume:	13
Issue:	1
Pages:	372-87

•

Publication

19144319 | J:143718

First Author:	Trost M
Year:	2009
Journal:	Immunity
Title:	The phagosomal proteome in interferon-gamma-activated macrophages.
Volume:	30
Issue:	1
Pages:	143-54

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=200&searchTerm=Cnot4

MouseMine

Search our database by keyword

Examples

Search results 201 to 254 out of 254 for Cnot4

Categories

Hits by Pathway

Hits by Category

Hits by Strain