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Search results 201 to 288 out of 288 for Cpa3

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Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Allele
Tg(Cpa3-cre)4Glli | MGI:5607597
Name: transgene insertion 4, Stephen J Galli
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Cpa3<em2(cre/ERT2)Smoc> | MGI:6724375
Name: carboxypeptidase A3, mast cell; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Strain
MGI:6428476 | C57BL/6JSmoc-Cpa3<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:5607595 | C57BL/6-Tg(Cpa3-cre)4Glli/J
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6428477 | C57BL/6JSmoc-Cpa3<em2(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Cpa3-cre)3Glli | MGI:5301437
Name: transgene insertion 3, Stephen J Galli
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
24391943 | J:209831
First Author: Jin X
Year: 2013
Journal: PLoS One
Title: Generation of a new congenic mouse strain with enhanced chymase expression in mast cells.
Volume: 8
Issue: 12
Pages: e84340
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Publication
21825171 | J:175983
First Author: Xing W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue.
Volume: 108
Issue: 34
Pages: 14210-5
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Publication
31077686 | J:326598
First Author: Roy S
Year: 2019
Journal: J Allergy Clin Immunol
Title: β-Arrestin2 expressed in mast cells regulates ciprofloxacin-induced pseudoallergy and IgE-mediated anaphylaxis.
Volume: 144
Issue: 2
Pages: 603-606
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Publication
26425734 | J:258178
First Author: Gendrin C
Year: 2015
Journal: Sci Adv
Title: Mast cell degranulation by a hemolytic lipid toxin decreases GBS colonization and infection.
Volume: 1
Issue: 6
Pages: e1400225
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Publication
37063868 | J:340255
 
First Author: Thapaliya M
Year: 2023
Journal: Front Immunol
Title: GRK2 differentially regulates FcεRI and MRGPRB2-mediated responses in mast cells.
Volume: 14
Pages: 1155777
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Genotype
Genotype
Symbol: Mcl1/Mcl1 Tg(Cpa3-cre)3Glli/?
Background: involves: 129X1/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Protein Domain
IPR001516 | Proton_antipo_N
Type: Domain
Description: Mrp-type antiporters comprise the cation/proton antiporter family 3 (CPA3), commonly referred to as Mrp. They are the products of operons that carry either six or seven genes (mrpA-G), and form complexes containing all subunits [, ]. They have Na(+)/H(+) antiporter activity []. Two of the Mrp proteins, MrpA and MrpD, resemble NuoL/ND5, NuoM/ND4, NuoN/ND2, the homologous subunits that constitute the membrane-embedded, proton-translocating core of complex I [, , , ]. They also resemble subunits of membrane-bound hydrogenases, such as HyfB, HyfD and HyfF from E.coli []and F420H2 dehydrogenasa (FPO complex) subunits L, N and M [].This domain represents an N-terminal extension of . It is found in complex I subunit NuoL/ND5, CPA3 antiporters subunit MrpA, and in F(420)H(2) dehydrogenase subunit L. Only NADH-Ubiquinone chain 5 and eubacterial chain L are in this family. This sub-family is part of complex I which catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane.
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Publication
10383164 | J:55679
First Author: Huang H
Year: 1999
Journal: Cancer Res
Title: Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells.
Volume: 59
Issue: 12
Pages: 2981-8
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Publication
31084709 | J:276101
   
First Author: Wang Q
Year: 2019
Journal: Elife
Title: IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis.
Volume: 8
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Publication
31974364 | J:288178
First Author: Yabut JM
Year: 2020
Journal: Nat Commun
Title: Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance.
Volume: 11
Issue: 1
Pages: 463
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Publication
35644498 | J:326597
     
First Author: Roy S
Year: 2022
Journal: J Invest Dermatol
Title: Role of MrgprB2 in Rosacea-Like Inflammation in Mice: Modulation by β-Arrestin 2.
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Publication
22906983 | J:189899
First Author: Oka T
Year: 2012
Journal: Lab Invest
Title: Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice.
Volume: 92
Issue: 10
Pages: 1472-82
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Publication
28283060 | J:241289
First Author: Ho CCM
Year: 2017
Journal: Cell
Title: Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.
Volume: 168
Issue: 6
Pages: 1041-1052.e18
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Publication
24030387 | J:204074
First Author: Leveson-Gower DB
Year: 2013
Journal: Blood
Title: Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells.
Volume: 122
Issue: 22
Pages: 3659-65
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Publication
24210352 | J:208997
First Author: Marichal T
Year: 2013
Journal: Immunity
Title: A beneficial role for immunoglobulin E in host defense against honeybee venom.
Volume: 39
Issue: 5
Pages: 963-75
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Publication
31591569 | J:305539
First Author: Serhan N
Year: 2019
Journal: Nat Immunol
Title: House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation.
Volume: 20
Issue: 11
Pages: 1435-1443
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Publication
35561839 | J:335792
First Author: Wang Y
Year: 2022
Journal: J Allergy Clin Immunol
Title: Dynamin-related protein 1 differentially regulates FcεRI- and substance P-induced mast cell activation.
Volume: 150
Issue: 5
Pages: 1228-1231.e5
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Publication
24142251 | -
First Author: Morino M
Year: 2014
Journal: J Bacteriol
Title: Purification and functional reconstitution of a seven-subunit mrp-type na+/h+ antiporter.
Volume: 196
Issue: 1
Pages: 28-35
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Publication
15980940 | -
First Author: Swartz TH
Year: 2005
Journal: Extremophiles
Title: The Mrp system: a giant among monovalent cation/proton antiporters?
Volume: 9
Issue: 5
Pages: 345-54
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Publication
18408029 | -
First Author: Morino M
Year: 2008
Journal: J Bacteriol
Title: Single gene deletions of mrpA to mrpG and mrpE point mutations affect activity of the Mrp Na+/H+ antiporter of alkaliphilic Bacillus and formation of hetero-oligomeric Mrp complexes.
Volume: 190
Issue: 12
Pages: 4162-72
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Publication
12914915 | -
First Author: Mathiesen C
Year: 2003
Journal: FEBS Lett
Title: The 'antiporter module' of respiratory chain complex I includes the MrpC/NuoK subunit -- a revision of the modular evolution scheme.
Volume: 549
Issue: 1-3
Pages: 7-13
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Publication
20826797 | -
First Author: Nakamaru-Ogiso E
Year: 2010
Journal: J Biol Chem
Title: The membrane subunit NuoL(ND5) is involved in the indirect proton pumping mechanism of Escherichia coli complex I.
Volume: 285
Issue: 50
Pages: 39070-8
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Publication
12460669 | -
First Author: Mathiesen C
Year: 2002
Journal: Biochim Biophys Acta
Title: Transmembrane topology of the NuoL, M and N subunits of NADH:quinone oxidoreductase and their homologues among membrane-bound hydrogenases and bona fide antiporters.
Volume: 1556
Issue: 2-3
Pages: 121-32
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Publication
20595580 | -
First Author: Hunte C
Year: 2010
Journal: Science
Title: Functional modules and structural basis of conformational coupling in mitochondrial complex I.
Volume: 329
Issue: 5990
Pages: 448-51
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Publication
9387241 | -
 
First Author: Andrews SC
Year: 1997
Journal: Microbiology
Title: A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system.
Volume: 143 ( Pt 11)
Pages: 3633-47
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Publication
27555460 | J:287019
First Author: Balbino B
Year: 2017
Journal: J Allergy Clin Immunol
Title: Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis.
Volume: 139
Issue: 2
Pages: 584-596.e10
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Publication
27786273 | J:242637
 
First Author: Yip KH
Year: 2016
Journal: Nat Commun
Title: The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation.
Volume: 7
Pages: 13198
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Publication
23544053 | J:199526
First Author: Nauta AC
Year: 2013
Journal: PLoS One
Title: Evidence that mast cells are not required for healing of splinted cutaneous excisional wounds in mice.
Volume: 8
Issue: 3
Pages: e59167
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Publication
23915716 | J:205536
First Author: Reber LL
Year: 2013
Journal: J Allergy Clin Immunol
Title: Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.
Volume: 132
Issue: 4
Pages: 881-8.e1-11
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Publication
25134760 | J:214825
First Author: Arac A
Year: 2014
Journal: Am J Pathol
Title: Evidence that meningeal mast cells can worsen stroke pathology in mice.
Volume: 184
Issue: 9
Pages: 2493-504
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Publication
28469089 | J:288010
 
First Author: Reber LL
Year: 2017
Journal: JCI Insight
Title: Imaging protective mast cells in living mice during severe contact hypersensitivity.
Volume: 2
Issue: 9
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Publication
23752044 | J:202870
First Author: Ando T
Year: 2013
Journal: J Invest Dermatol
Title: Mast cells are required for full expression of allergen/SEB-induced skin inflammation.
Volume: 133
Issue: 12
Pages: 2695-2705
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Publication
28264908 | J:286944
 
First Author: Mukai K
Year: 2017
Journal: Infect Immun
Title: Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4+ T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis.
Volume: 85
Issue: 5
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Publication
24943488 | J:337159
First Author: Reber LL
Year: 2014
Journal: Arthritis Rheumatol
Title: Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice.
Volume: 66
Issue: 10
Pages: 2881-91
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Publication
37566453 | J:354783
   
First Author: Jackson WD
Year: 2023
Journal: Elife
Title: TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity.
Volume: 12
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Publication
29277702 | J:267856
First Author: Li Y
Year: 2018
Journal: J Allergy Clin Immunol
Title: The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.
Volume: 142
Issue: 4
Pages: 1173-1184
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Protein
P03921
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A067XKN8
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A3R488
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
B9V1K9
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A067XKV1
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A0F6PYU6
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6A9
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J679
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6C1
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
Q4JFM6
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
Q9MD82
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
K7XJX5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
N0DTI5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A141CM25
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A075DCB1
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A067XL99
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
B9V192
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A141CM51
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A3R462
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6J5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
Q3TRR5
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: true
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Protein
A0A023J672
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6L2
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A3E4B7
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J5Z8
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J5X2
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6F2
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6I6
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A6M8U123
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A141CM38
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
Q7JCZ8
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
Q5GA74
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
Q7GIP3
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6G8
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J627
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J611
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J6G4
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A3R4A1
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J5Y5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A023J655
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Protein
A0A067XKW0
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
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Publication
10751389 | -
First Author: Baumer S
Year: 2000
Journal: J Biol Chem
Title: The F420H2 dehydrogenase from Methanosarcina mazei is a Redox-driven proton pump closely related to NADH dehydrogenases.
Volume: 275
Issue: 24
Pages: 17968-73
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Publication
38427721 | J:346919
First Author: De Giovanni M
Year: 2024
Journal: Sci Immunol
Title: Mast cells help organize the Peyer's patch niche for induction of IgA responses.
Volume: 9
Issue: 93
Pages: eadj7363
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Publication
37279752 | J:337857
First Author: De Giovanni M
Year: 2023
Journal: Immunity
Title: Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system.
Volume: 56
Issue: 7
Pages: 1548-1560.e5
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Publication
32160525 | J:288632
First Author: McGinty JW
Year: 2020
Journal: Immunity
Title: Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity.
Volume: 52
Issue: 3
Pages: 528-541.e7
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Publication
33220232 | J:302271
First Author: Chen Z
Year: 2021
Journal: Immunity
Title: Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis.
Volume: 54
Issue: 1
Pages: 151-163.e6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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