|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 222 out of 222 for Cxcr6

<< First    < Previous  |  Next >    Last >>
0.017s
Type Details Score
Publication
First Author: Chu KL
Year: 2020
Journal: J Leukoc Biol
Title: GITR differentially affects lung effector T cell subpopulations during influenza virus infection.
Volume: 107
Issue: 6
Pages: 953-970
Publication
First Author: Zaid A
Year: 2017
Journal: J Immunol
Title: Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.
Volume: 199
Issue: 7
Pages: 2451-2459
Publication
First Author: Soundararajan R
Year: 2016
Journal: Aging (Albany NY)
Title: Global gene profiling of aging lungs in Atp8b1 mutant mice.
Volume: 8
Issue: 9
Pages: 2232-2252
Publication
First Author: Ueha S
Year: 2007
Journal: J Leukoc Biol
Title: Intervention of MAdCAM-1 or fractalkine alleviates graft-versus-host reaction associated intestinal injury while preserving graft-versus-tumor effects.
Volume: 81
Issue: 1
Pages: 176-85
Publication
First Author: Tu GW
Year: 2019
Journal: J Cell Mol Med
Title: CXCL16/CXCR6 is involved in LPS-induced acute lung injury via P38 signalling.
Volume: 23
Issue: 8
Pages: 5380-5389
Publication  
First Author: Cassidy MF
Year: 2022
Journal: Mol Immunol
Title: Splicing factor SRSF1 controls autoimmune-related molecular pathways in regulatory T cells distinct from FoxP3.
Volume: 152
Pages: 140-152
Publication  
First Author: Sandor AM
Year: 2019
Journal: Front Immunol
Title: CD11c+ Cells Are Gatekeepers for Lymphocyte Trafficking to Infiltrated Islets During Type 1 Diabetes.
Volume: 10
Pages: 99
Publication  
First Author: Su X
Year: 2023
Journal: Front Immunol
Title: γδ T cells recruitment and local proliferation in brain parenchyma benefit anti-neuroinflammation after cerebral microbleeds.
Volume: 14
Pages: 1139601
Publication
First Author: Shimaoka T
Year: 2000
Journal: J Biol Chem
Title: Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages.
Volume: 275
Issue: 52
Pages: 40663-6
Protein
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: false
Publication
First Author: Abel S
Year: 2004
Journal: J Immunol
Title: The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10.
Volume: 172
Issue: 10
Pages: 6362-72
Protein Domain
Type: Family
Description: Chemokines are proteins that have important physiological and pathophysiological roles in a wide range of acute and chronic inflammatory processes []. Chemokines exert their biological effects by binding to cell surface receptors. Their sequences are similar and are characterised by a 4-cysteine motif: the family can be divided according to whether the first 2Cys residues are adjacent (the C-C family), separated by an intervening residue (the C-x-C family), have only one of the first two Cys residues (C chemokines), or contain both cysteines, separated by threeintervening residues (C-x3-C chemokines). This entry represents a novel chemokine, chemokine (C-X-C motif) ligand 16 (CXCL16), has been identified that is a member of the C-X-C family [, ], it is also called SR-PSOX. Despite possessing the CXC motif, however, it is distantly related to the other family members and has greatest sequence similarity to members of the C-C family []. CXCL16 also differs in structure from the other family members (all of which are secreted proteins) and contains a TM domain linked to the chemokine domain by a heavily glycosylated mucin stalk. This structure is similar to that of the CX3C chemokine ligand 1 (CX3C chemokine fractalkine), the only other known chemokine with a TM domain. CXCL16 has been found to be expressed in the spleen, lymph nodes, Peyer's patches and thymus. In non-lymphoid tissues, CXCL16 is found in the lung, small intestine, kidney, heart and liver []. The chemokine appears to be expressed as a membrane-bound cell surface ligand on antigen presenting cells (APCs), such as B cells and macrophages []. CXCL16 can also be shed from the cell surface in an active, soluble form [, ]. These two forms may have different functions. Expression of CXCL16 is upregulated by exposure to inflammatory stimuli.CXCL16 induces a strong chemotactic response. It induces calcium mobilisation and binds to chemokine receptor CXCR6 and HIV-coreceptor Bonzo [, ]. It also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis []. Expression of CXCL16 is induced by the inflammatory cytokines IFN-gamma and TNF-alpha [].
Publication
First Author: Chalabi-Dchar M
Year: 2015
Journal: Gastroenterology
Title: Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Volume: 148
Issue: 7
Pages: 1452-65
Publication
First Author: Horuk R
Year: 2001
Journal: Cytokine Growth Factor Rev
Title: Chemokine receptors.
Volume: 12
Issue: 4
Pages: 313-35
Publication
First Author: Ma Q
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.
Volume: 95
Issue: 16
Pages: 9448-53
Publication
First Author: Charbonnier AS
Year: 1999
Journal: J Exp Med
Title: Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal langerhans cells.
Volume: 190
Issue: 12
Pages: 1755-68
Publication
First Author: Sallusto F
Year: 1998
Journal: J Exp Med
Title: Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes.
Volume: 187
Issue: 6
Pages: 875-83
Publication
First Author: Strieter RM
Year: 1995
Journal: J Biol Chem
Title: The functional role of the ELR motif in CXC chemokine-mediated angiogenesis.
Volume: 270
Issue: 45
Pages: 27348-57
Publication
First Author: Zlotnik A
Year: 2000
Journal: Immunity
Title: Chemokines: a new classification system and their role in immunity.
Volume: 12
Issue: 2
Pages: 121-7