Type |
Details |
Score |
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
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•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu C |
Year: |
2011 |
Journal: |
Nat Commun |
Title: |
The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. |
Volume: |
2 |
|
Pages: |
227 |
|
•
•
•
•
•
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Publication |
First Author: |
Sommermeyer V |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
Spp1, a member of the Set1 Complex, promotes meiotic DSB formation in promoters by tethering histone H3K4 methylation sites to chromosome axes. |
Volume: |
49 |
Issue: |
1 |
Pages: |
43-54 |
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•
•
•
•
•
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Protein Domain |
Type: |
Family |
Description: |
Spp1 is a component of the COMPASS (Set1C) complex []. It promotes meiotic DNA double-strand break formation in promoters by tethering histone H3K4 methylation sites to chromosome axes []. This entry also includes CXXC-type zinc finger protein 1 (also known as CFP1) from animals [].CXXC-type zinc finger protein 1 (CXXC1 or CFP1) is a component of the SETD1 histone H3K4 methyltransferase complex. CXXC1 directs the complex to a chromatin region via its CXXC zinc finger with a specificity for a CpG unmethylated motif, particularly CpGG [, ].The COMPASS (Complex Proteins Associated with Set1 or Set1C) is the yeast homologue of the human MLL complex, which is required for mono-, di-, and trimethylation of lysine 4 of histone H3 []. It is required in telomeric transcriptional silencing []. The complex consists of Set1, Bre2, Spp1, Sdc1, Shg1, Swd1, Swd2, and Swd3 [, ]. |
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•
•
•
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•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
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Publication |
First Author: |
Voo KS |
Year: |
2000 |
Journal: |
Mol Cell Biol |
Title: |
Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. |
Volume: |
20 |
Issue: |
6 |
Pages: |
2108-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schneider J |
Year: |
2005 |
Journal: |
Mol Cell |
Title: |
Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. |
Volume: |
19 |
Issue: |
6 |
Pages: |
849-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imai Y |
Year: |
2017 |
Journal: |
Chromosoma |
Title: |
The PRDM9 KRAB domain is required for meiosis and involved in protein interactions. |
Volume: |
126 |
Issue: |
6 |
Pages: |
681-695 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krogan NJ |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. |
Volume: |
277 |
Issue: |
13 |
Pages: |
10753-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roguev A |
Year: |
2001 |
Journal: |
EMBO J |
Title: |
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. |
Volume: |
20 |
Issue: |
24 |
Pages: |
7137-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miller T |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
COMPASS: a complex of proteins associated with a trithorax-related SET domain protein. |
Volume: |
98 |
Issue: |
23 |
Pages: |
12902-7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
660
 |
Fragment?: |
false |
|
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
660
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
660
 |
Fragment?: |
false |
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•
•
•
|