Type |
Details |
Score |
Publication |
First Author: |
Fu ZD |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice. |
Volume: |
10 |
Issue: |
9 |
Pages: |
e0138307 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee YK |
Year: |
2008 |
Journal: |
Mol Endocrinol |
Title: |
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1345-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lou G |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells. |
Volume: |
9 |
Issue: |
4 |
Pages: |
e93567 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weerachayaphorn J |
Year: |
2012 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. |
Volume: |
302 |
Issue: |
9 |
Pages: |
G925-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chartoumpekis DV |
Year: |
2013 |
Journal: |
Oxid Med Cell Longev |
Title: |
Hepatic gene expression profiling in Nrf2 knockout mice after long-term high-fat diet-induced obesity. |
Volume: |
2013 |
|
Pages: |
340731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi K |
Year: |
2014 |
Journal: |
Biochim Biophys Acta |
Title: |
Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice. |
Volume: |
1840 |
Issue: |
7 |
Pages: |
2289-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie Y |
Year: |
2009 |
Journal: |
J Lipid Res |
Title: |
Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice. |
Volume: |
50 |
Issue: |
5 |
Pages: |
977-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heverin M |
Year: |
2007 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol. |
Volume: |
27 |
Issue: |
10 |
Pages: |
2191-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cingolani F |
Year: |
2022 |
Journal: |
Hepatol Commun |
Title: |
Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down-Regulation of Bile Acid Synthesis. |
Volume: |
6 |
Issue: |
5 |
Pages: |
980-994 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parker RA |
Year: |
2013 |
Journal: |
J Lipid Res |
Title: |
Bile acid and sterol metabolism with combined HMG-CoA reductase and PCSK9 suppression. |
Volume: |
54 |
Issue: |
9 |
Pages: |
2400-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2006 |
Journal: |
J Lipid Res |
Title: |
Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice. |
Volume: |
47 |
Issue: |
2 |
Pages: |
421-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Staudinger J |
Year: |
2001 |
Journal: |
Drug Metab Dispos |
Title: |
Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor. |
Volume: |
29 |
Issue: |
11 |
Pages: |
1467-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lynch EC |
Year: |
2022 |
Journal: |
PLoS One |
Title: |
Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model. |
Volume: |
17 |
Issue: |
6 |
Pages: |
e0268344 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ballatori N |
Year: |
2008 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. |
Volume: |
295 |
Issue: |
1 |
Pages: |
G179-G186 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmering J |
Year: |
2014 |
Journal: |
Lipids Health Dis |
Title: |
A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice. |
Volume: |
13 |
|
Pages: |
167 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim EH |
Year: |
2012 |
Journal: |
Biochem Pharmacol |
Title: |
Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease. |
Volume: |
84 |
Issue: |
10 |
Pages: |
1359-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chanda D |
Year: |
2010 |
Journal: |
Nucleic Acids Res |
Title: |
Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation. |
Volume: |
38 |
Issue: |
14 |
Pages: |
4607-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Drover VA |
Year: |
2004 |
Journal: |
Endocrinology |
Title: |
Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice. |
Volume: |
145 |
Issue: |
2 |
Pages: |
574-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han S |
Year: |
2010 |
Journal: |
Mol Endocrinol |
Title: |
A novel bile acid-activated vitamin D receptor signaling in human hepatocytes. |
Volume: |
24 |
Issue: |
6 |
Pages: |
1151-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Buler M |
Year: |
2011 |
Journal: |
Biochem Pharmacol |
Title: |
Energy sensing factors PGC-1α and SIRT1 modulate PXR expression and function. |
Volume: |
82 |
Issue: |
12 |
Pages: |
2008-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Henkel AS |
Year: |
2013 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation. |
Volume: |
304 |
Issue: |
2 |
Pages: |
G221-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo J |
Year: |
2014 |
Journal: |
Sci Transl Med |
Title: |
A nontumorigenic variant of FGF19 treats cholestatic liver diseases. |
Volume: |
6 |
Issue: |
247 |
Pages: |
247ra100 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elias I |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. |
Volume: |
65 |
Issue: |
8 |
Pages: |
2139-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Athanason MG |
Year: |
2016 |
Journal: |
Mol Cell Endocrinol |
Title: |
Quantitative proteomic profiling reveals hepatic lipogenesis and liver X receptor activation in the PANDER transgenic model. |
Volume: |
436 |
|
Pages: |
41-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2014 |
Journal: |
Curr Mol Med |
Title: |
Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity. |
Volume: |
14 |
Issue: |
6 |
Pages: |
703-711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shaw RPH |
Year: |
2022 |
Journal: |
Endocrinology |
Title: |
Loss of Hepatic Small Heterodimer Partner Elevates Ileal Bile Acids and Alters Cell Cycle-related Genes in Male Mice. |
Volume: |
163 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bhat N |
Year: |
2022 |
Journal: |
FASEB J |
Title: |
TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. |
Volume: |
36 |
Issue: |
3 |
Pages: |
e22185 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi T |
Year: |
2024 |
Journal: |
Biochem Pharmacol |
Title: |
Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F(2α) (PGF(2α)) levels. |
Volume: |
225 |
|
Pages: |
116309 |
|
•
•
•
•
•
|
Publication |
First Author: |
Slijepcevic D |
Year: |
2017 |
Journal: |
Hepatology |
Title: |
Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice. |
Volume: |
66 |
Issue: |
5 |
Pages: |
1631-1643 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trenteseaux C |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Perinatal Hypercholesterolemia Exacerbates Atherosclerosis Lesions in Offspring by Altering Metabolism of Trimethylamine-N-Oxide and Bile Acids. |
Volume: |
37 |
Issue: |
11 |
Pages: |
2053-2063 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matasconi M |
Year: |
2005 |
Journal: |
Biochim Biophys Acta |
Title: |
Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment. |
Volume: |
1736 |
Issue: |
3 |
Pages: |
221-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ellis EC |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Mice with chimeric livers are an improved model for human lipoprotein metabolism. |
Volume: |
8 |
Issue: |
11 |
Pages: |
e78550 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2017 |
Journal: |
Toxicol Sci |
Title: |
Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner. |
Volume: |
160 |
Issue: |
2 |
Pages: |
351-360 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu C |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. |
Volume: |
280 |
Issue: |
18 |
Pages: |
17707-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zollner G |
Year: |
2006 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids. |
Volume: |
290 |
Issue: |
5 |
Pages: |
G923-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamoto Y |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. |
Volume: |
281 |
Issue: |
24 |
Pages: |
16625-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song Y |
Year: |
2015 |
Journal: |
J Hepatol |
Title: |
Thyroid-stimulating hormone regulates hepatic bile acid homeostasis via SREBP-2/HNF-4α/CYP7A1 axis. |
Volume: |
62 |
Issue: |
5 |
Pages: |
1171-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christensen KE |
Year: |
2015 |
Journal: |
Am J Clin Nutr |
Title: |
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. |
Volume: |
101 |
Issue: |
3 |
Pages: |
646-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stroeve JH |
Year: |
2010 |
Journal: |
Lab Invest |
Title: |
Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice. |
Volume: |
90 |
Issue: |
10 |
Pages: |
1457-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quinet EM |
Year: |
2006 |
Journal: |
Mol Pharmacol |
Title: |
Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting. |
Volume: |
70 |
Issue: |
4 |
Pages: |
1340-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber AA |
Year: |
2021 |
Journal: |
Drug Metab Dispos |
Title: |
Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation. |
Volume: |
49 |
Issue: |
1 |
Pages: |
12-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park YJ |
Year: |
2008 |
Journal: |
Hepatology |
Title: |
Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis. |
Volume: |
47 |
Issue: |
5 |
Pages: |
1578-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lukovac S |
Year: |
2009 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice. |
Volume: |
297 |
Issue: |
3 |
Pages: |
G520-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang S |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. |
Volume: |
27 |
Issue: |
4 |
Pages: |
1407-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen JT |
Year: |
2021 |
Journal: |
Endocrinology |
Title: |
Deletion of Intestinal SHP Impairs Short-term Response to Cholic Acid Challenge in Male Mice. |
Volume: |
162 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dong Z |
Year: |
2022 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis. |
Volume: |
13 |
Issue: |
4 |
Pages: |
1161-1179 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
470
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
500
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
507
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
501
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
509
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
470
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
507
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
507
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
500
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
 |
Fragment?: |
false |
|
•
•
•
•
•
|