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Search results 201 to 300 out of 306 for Ddah1

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Type Details Score
GXD Expression    
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:3584771
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3585876
Age: postnatal day 8-10
Image: P8/10
Note: Expression was detected in a subset of ganglion cells at the periphery.
Specimen Label: P8/10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Image: EG404; Specimen G0240
Specimen Label: EG404; Specimen G0240
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1634615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4437725
Age: embryonic day 9.5
Note: Expression is in the outer curvature.
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1634615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4437725
Age: embryonic day 9.5
Note: Expression is in the outer curvature.
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Image: EG404; Specimen G0240
Specimen Label: EG404; Specimen G0240
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4437725
Age: embryonic day 10.5
Specimen Label: 2E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4437702
Assay Type: Immunohistochemistry
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160469
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:4437703
Age: embryonic day 6.5
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4437725
Age: embryonic day 9.5
Note: Expression is in the outer curvature.
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4437725
Age: embryonic day 9.5
Note: Expression is in the outer curvature.
Specimen Label: 2D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4437725
Age: embryonic day 10.5
Specimen Label: 2E
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Image: EG404; Specimen G0240
Specimen Label: EG404; Specimen G0240
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Image: EG404; Specimen G0240
Specimen Label: EG404; Specimen G0240
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Image: EG404; Specimen G0240
Specimen Label: EG404; Specimen G0240
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_07
Note: facial motor nucleus
Specimen Label: euxassay_003952_07
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_14
Note: facial motor nucleus
Specimen Label: euxassay_003952_14
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_11
Specimen Label: euxassay_003952_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_12
Specimen Label: euxassay_003952_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_13
Specimen Label: euxassay_003952_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_16
Specimen Label: euxassay_003952_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1753199
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824261
Age: embryonic day 14.5
Image: euxassay_003952_17
Specimen Label: euxassay_003952_17
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:4437697
Assay Type: RNA in situ
Annotation Date: 2010-03-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4437725
Age: embryonic day 14.5
Specimen Label: 2H
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309648
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423004
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EG404; Specimen G0240
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3584771
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3585876
Age: embryonic day 14.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3584771
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3747120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3585876
Age: embryonic day 12.0
Specimen Label: Embryo
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:3584771
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3747122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3585876
Age: embryonic day 14.0
Specimen Label: Embryo
Detected: true
Specimen Num: 14
Publication
First Author: Ragavan VN
Year: 2023
Journal: Nat Commun
Title: A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase.
Volume: 14
Issue: 1
Pages: 3392
Publication
First Author: Palm F
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems.
Volume: 293
Issue: 6
Pages: H3227-45
Publication
First Author: Jacobi J
Year: 2010
Journal: Am J Pathol
Title: Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine.
Volume: 176
Issue: 5
Pages: 2559-70
Publication
First Author: Pullamsetti SS
Year: 2011
Journal: Sci Transl Med
Title: The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.
Volume: 3
Issue: 87
Pages: 87ra53
Publication  
First Author: Xu J
Year: 2021
Journal: Front Cell Dev Biol
Title: Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.
Volume: 9
Pages: 665109
Publication
First Author: Xu J
Year: 2020
Journal: J Dent Res
Title: Genome-wide Identification of Foxf2 Target Genes in Palate Development.
Volume: 99
Issue: 4
Pages: 463-471
Publication
First Author: Kawaguchi A
Year: 2008
Journal: Development
Title: Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis.
Volume: 135
Issue: 18
Pages: 3113-24
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: transgene insertion 1, John P Cooke
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Swärd K
Year: 2013
Journal: Physiol Rep
Title: Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF.
Volume: 1
Issue: 1
Pages: e00008
HT Experiment
Series Id: GSE43561
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Protein Domain
Type: Family
Description: Mammalian dimethylarginine dimethylaminohydrolases DDAH1 and DDAH2 have homology with microbial arginine deiminases [], all of them are included in this entry.DDAH hydrolyzes both N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA), two nitric oxide synthase (NOS) inhibitors to yield L-citrulline and the corresponding alkylamine []. This way DDAH relieves the inhibition of NOS and promotes NO biosynthesis. Two isoforms exist, DDAH1 and DDAH2. DDAH1 predominates in tissues that express neuronal NOS []. DDAH2 expression predominates in highly vascularized tissues that express the endothelial NOS isoform and in immune tissues that can express iNOS [].
Protein
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
Publication
First Author: Tran CT
Year: 2000
Journal: Genomics
Title: Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins.
Volume: 68
Issue: 1
Pages: 101-5
Publication
First Author: Liu LH
Year: 2012
Journal: Cell Physiol Biochem
Title: Protection of DDAH2 overexpression against homocysteine-induced impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells.
Volume: 30
Issue: 6
Pages: 1413-22
Protein Domain
Type: Family
Description: Dimethylarginine dimethylaminohydrolase (DDAH) modulates nitric oxide (NO) synthesis via metabolizing asymmetric dimethylarginine (ADMA), an endogenous NO synthase (NOS) inhibitor. Two isoforms of human dimethylarginine dimethylaminohydrolase exist, DDAH1 and DDAH2, with distinct tissue distributions. DDAH 1 predominates in tissues that express neuronal NOS []. DDAH2 expression predominates in highly vascularized tissues that express the endothelial NOS isoform and in immune tissues that can express iNOS [, ].
Publication
First Author: von Leitner EC
Year: 2011
Journal: Circulation
Title: Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
Volume: 124
Issue: 24
Pages: 2735-45
Publication
First Author: Wang Y
Year: 2019
Journal: FASEB J
Title: Neuropilin-1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells, and contributes to protection from angiotensin II-induced hypertension.
Volume: 33
Issue: 1
Pages: 494-500
Publication
First Author: Rodionov RN
Year: 2010
Journal: Circ Res
Title: Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia.
Volume: 106
Issue: 3
Pages: 551-8