Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the immune system. |
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1741222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584771 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3573928 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3585876 |
Age: |
postnatal day 8-10 |
Image: |
P8/10 |
Note: |
Expression was detected in a subset of ganglion cells at the periphery. |
Specimen Label: |
P8/10 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
Image: |
EG404; Specimen G0240 |
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1634615 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression is in the outer curvature. |
Specimen Label: |
2C |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1634615 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression is in the outer curvature. |
Specimen Label: |
2D |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3599822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280922 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
Image: |
EG404; Specimen G0240 |
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1833322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
2E |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437702 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160469 |
Pattern: |
Not Specified |
Stage: |
TS09 |
Assay Id: |
MGI:4437703 |
Age: |
embryonic day 6.5 |
|
|
Specimen Label: |
1A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1635015 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression is in the outer curvature. |
Specimen Label: |
2C |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1635015 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression is in the outer curvature. |
Specimen Label: |
2D |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1635017 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
2E |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1821522 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
Image: |
EG404; Specimen G0240 |
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3557722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756322 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
Image: |
EG404; Specimen G0240 |
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1668822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757722 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
Image: |
EG404; Specimen G0240 |
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_07 |
Note: |
facial motor nucleus |
Specimen Label: |
euxassay_003952_07 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_14 |
Note: |
facial motor nucleus |
Specimen Label: |
euxassay_003952_14 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1802422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_11 |
|
Specimen Label: |
euxassay_003952_11 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_12 |
|
Specimen Label: |
euxassay_003952_12 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_13 |
|
Specimen Label: |
euxassay_003952_13 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_16 |
|
Specimen Label: |
euxassay_003952_16 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1753199 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778223 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824261 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003952_17 |
|
Specimen Label: |
euxassay_003952_17 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4437697 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-03-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689422 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4437725 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
2H |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the skull (base and vault). |
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5309648 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423004 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in whisker follicle. |
Specimen Label: |
EG404; Specimen G0240 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584771 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3585876 |
Age: |
embryonic day 14.0 |
|
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
E14 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584771 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:3585876 |
Age: |
embryonic day 12.0 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584771 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3747122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3585876 |
Age: |
embryonic day 14.0 |
|
|
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ragavan VN |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase. |
Volume: |
14 |
Issue: |
1 |
Pages: |
3392 |
|
•
•
•
•
•
|
Publication |
First Author: |
Palm F |
Year: |
2007 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems. |
Volume: |
293 |
Issue: |
6 |
Pages: |
H3227-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jacobi J |
Year: |
2010 |
Journal: |
Am J Pathol |
Title: |
Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine. |
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Mouse Genome Informatics Scientific Curators |
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Title: |
RIKEN Data Curation in Mouse Genome Informatics |
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Mouse Genome Informatics Scientific Curators |
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2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
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Nucleic Acids Res |
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Front Mol Neurosci |
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Database Download |
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WashU-HHMI Mouse EST Project |
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International Mouse Strain Resource |
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Database Download |
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MGI download of germline transmission data for alleles from IMSR strain data |
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First Author: |
Wellcome Trust Sanger Institute |
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MGI Direct Data Submission |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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The Gene Ontology Consortium |
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2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Mouse Genome Informatics Scientific Curators |
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2003 |
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Title: |
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Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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The transcriptional landscape of the mammalian genome. |
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Nature |
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Proc Natl Acad Sci U S A |
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
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First Author: |
Skarnes WC |
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2011 |
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Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
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First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
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Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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First Author: |
GOA curators |
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Title: |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
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Mouse T31 Radiation Hybrid Data Load |
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First Author: |
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Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
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The Gene Ontology Consortium |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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PLoS Biol |
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Mouse Genome Informatics Computational Sequence to Gene Associations |
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Year: |
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Title: |
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Mouse Genome Database and National Center for Biotechnology Information |
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Title: |
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First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
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Journal: |
Database Download |
Title: |
Consensus CDS project |
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First Author: |
Mouse Genome Informatics Group |
Year: |
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Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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First Author: |
Mouse Genome Informatics Scientific Curators |
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2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Allele |
Name: |
transgene insertion 1, John P Cooke |
Allele Type: |
Transgenic |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
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Publication |
First Author: |
Swärd K |
Year: |
2013 |
Journal: |
Physiol Rep |
Title: |
Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF. |
Volume: |
1 |
Issue: |
1 |
Pages: |
e00008 |
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HT Experiment |
Series Id: |
GSE43561 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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Protein Domain |
Type: |
Family |
Description: |
Mammalian dimethylarginine dimethylaminohydrolases DDAH1 and DDAH2 have homology with microbial arginine deiminases [], all of them are included in this entry.DDAH hydrolyzes both N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA), two nitric oxide synthase (NOS) inhibitors to yield L-citrulline and the corresponding alkylamine []. This way DDAH relieves the inhibition of NOS and promotes NO biosynthesis. Two isoforms exist, DDAH1 and DDAH2. DDAH1 predominates in tissues that express neuronal NOS []. DDAH2 expression predominates in highly vascularized tissues that express the endothelial NOS isoform and in immune tissues that can express iNOS []. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
285
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
75
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
157
 |
Fragment?: |
true |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
244
 |
Fragment?: |
false |
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Publication |
First Author: |
Tran CT |
Year: |
2000 |
Journal: |
Genomics |
Title: |
Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. |
Volume: |
68 |
Issue: |
1 |
Pages: |
101-5 |
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•
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•
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Publication |
First Author: |
Liu LH |
Year: |
2012 |
Journal: |
Cell Physiol Biochem |
Title: |
Protection of DDAH2 overexpression against homocysteine-induced impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1413-22 |
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•
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Protein Domain |
Type: |
Family |
Description: |
Dimethylarginine dimethylaminohydrolase (DDAH) modulates nitric oxide (NO) synthesis via metabolizing asymmetric dimethylarginine (ADMA), an endogenous NO synthase (NOS) inhibitor. Two isoforms of human dimethylarginine dimethylaminohydrolase exist, DDAH1 and DDAH2, with distinct tissue distributions. DDAH 1 predominates in tissues that express neuronal NOS []. DDAH2 expression predominates in highly vascularized tissues that express the endothelial NOS isoform and in immune tissues that can express iNOS [, ]. |
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Publication |
First Author: |
von Leitner EC |
Year: |
2011 |
Journal: |
Circulation |
Title: |
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase. |
Volume: |
124 |
Issue: |
24 |
Pages: |
2735-45 |
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Publication |
First Author: |
Wang Y |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Neuropilin-1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells, and contributes to protection from angiotensin II-induced hypertension. |
Volume: |
33 |
Issue: |
1 |
Pages: |
494-500 |
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Publication |
First Author: |
Rodionov RN |
Year: |
2010 |
Journal: |
Circ Res |
Title: |
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. |
Volume: |
106 |
Issue: |
3 |
Pages: |
551-8 |
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