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Search results 201 to 286 out of 286 for Ddr1

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5001580
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542134
Age: embryonic day 15.5
Image: GUDMAP:8704
Specimen Label: GUDMAP:8704
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:254906
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3586142
Age: embryonic day 14.0
Image: E14
Note: Expression was detected in the outer neuroblastic layer but was higher in a subset of cells.
Specimen Label: E14
Detected: true
Specimen Num: 1
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Publication
8302582 | J:17813
First Author: Perez JL
Year: 1994
Journal: Oncogene
Title: Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain.
Volume: 9
Issue: 1
Pages: 211-9
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Publication
26800565 | J:246304
First Author: Krohn JB
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Discoidin Domain Receptor-1 Regulates Calcific Extracellular Vesicle Release in Vascular Smooth Muscle Cell Fibrocalcific Response via Transforming Growth Factor-β Signaling.
Volume: 36
Issue: 3
Pages: 525-33
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Publication
20860797 | J:323413
 
First Author: Girgert R
Year: 2010
Journal: Fibrogenesis Tissue Repair
Title: Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney.
Volume: 3
Pages: 19
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Publication
20576036 | J:171784
First Author: Sturgess JE
Year: 2010
Journal: Eur J Neurosci
Title: Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects.
Volume: 32
Issue: 1
Pages: 143-54
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Publication
33930309 | J:306524
First Author: Affo S
Year: 2021
Journal: Cancer Cell
Title: Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.
Volume: 39
Issue: 6
Pages: 866-882.e11
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Publication
16603319 | J:108866
First Author: Franco-Pons N
Year: 2006
Journal: Neuroscience
Title: Expression of discoidin domain receptor 1 during mouse brain development follows the progress of myelination.
Volume: 140
Issue: 2
Pages: 463-75
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Publication
1281307 | J:3319
First Author: Gilardi-Hebenstreit P
Year: 1992
Journal: Oncogene
Title: An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.
Volume: 7
Issue: 12
Pages: 2499-506
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Publication
7558021 | J:27402
First Author: Bozza M
Year: 1995
Journal: Genomics
Title: Structural characterization and chromosomal location of the mouse macrophage migration inhibitory factor gene and pseudogenes.
Volume: 27
Issue: 3
Pages: 412-9
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Publication
36198802 | J:339972
First Author: Filliol A
Year: 2022
Journal: Nature
Title: Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.
Volume: 610
Issue: 7931
Pages: 356-365
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Publication
8530024 | J:25776
First Author: Steingrímsson E
Year: 1995
Journal: Genomics
Title: Murine chromosomal location of five bHLH-Zip transcription factor genes.
Volume: 28
Issue: 2
Pages: 179-83
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Publication
23382219 | J:194542
First Author: Ghai R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Volume: 110
Issue: 8
Pages: E643-52
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-GEOD-46577 | Interactions between Jag1 and Ddr1 in mouse liver
Series Id: GSE46577
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Ddr1<em1Smoc> | MGI:7289300
Name: discoidin domain receptor family, member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428524 | C57BL/6JSmoc-Ddr1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
24768818 | -
First Author: Canning P
Year: 2014
Journal: J Mol Biol
Title: Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors.
Volume: 426
Issue: 13
Pages: 2457-70
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Publication
9659899 | J:47333
First Author: Vogel W
Year: 1997
Journal: Mol Cell
Title: The discoidin domain receptor tyrosine kinases are activated by collagen.
Volume: 1
Issue: 1
Pages: 13-23
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Publication
9659900 | -
First Author: Shrivastava A
Year: 1997
Journal: Mol Cell
Title: An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors.
Volume: 1
Issue: 1
Pages: 25-34
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Publication
17665456 | -
First Author: Xu L
Year: 2007
Journal: Arthritis Rheum
Title: Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis.
Volume: 56
Issue: 8
Pages: 2663-73
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Publication
24781958 | -
First Author: Márquez J
Year: 2014
Journal: Histol Histopathol
Title: Role of discoidin domain receptor 2 in wound healing.
Volume: 29
Issue: 11
Pages: 1355-64
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Publication
22328973 | -
First Author: Hammerman PS
Year: 2011
Journal: Cancer Discov
Title: Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.
Volume: 1
Issue: 1
Pages: 78-89
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Publication
20884741 | -
First Author: Roberts ME
Year: 2011
Journal: Eur Respir J
Title: Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production.
Volume: 37
Issue: 6
Pages: 1482-93
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Publication
16234985 | -
First Author: Ram R
Year: 2006
Journal: J Neurooncol
Title: Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Volume: 76
Issue: 3
Pages: 239-48
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Protein Domain
IPR034299 | DDR1/DDR2
Type: Family
Description: The discoidin domain-containing receptor (DDR) family includes DDR1 and DDR2. DDR family members are receptor tyrosine kinases (RTKs) whose activating ligands are various collagens []. The proteins contain an extracellular discoidin domain, which binds various collagen proteins, and an intracellular tyrosine kinase domain.DDR2 may have a role in wound healing; DDR2 signalling regulates cell proliferation and extracellular matrix synthesis, which are key aspects of fibroblast contribution to tissue healing []. Increased expression of DDR2 may also be important in the pathogenesis of osteoarthritis [], and there is evidence that the receptor could be implicated in certain forms of cancer - mutations in the DDR2 kinase gene have been detected in ~ 4% of squamous cell lung cancers [].Epithelial discoidin domain-containing receptor 1 (also known as DDR1) is involved in smooth muscle cell migration and matrix metalloproteinase expression []. It is responsible for maintaining the normal structure of skin and kidney epithelia []. The receptor may play a critical role in inducing tumour cell adhesion and invasion []. Itsstructure has been solved [].
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Publication
18190796 | J:133423
First Author: Hilton HN
Year: 2008
Journal: Biochim Biophys Acta
Title: KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.
Volume: 1783
Issue: 3
Pages: 383-93
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Publication
35386458 | J:349760
 
First Author: Wang J
Year: 2022
Journal: Bioact Mater
Title: Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis.
Volume: 17
Pages: 406-424
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Publication
33173221 | J:300408
First Author: Wu R
Year: 2020
Journal: Sci Rep
Title: Fate and functional roles of Prominin 1+ cells in liver injury and cancer.
Volume: 10
Issue: 1
Pages: 19412
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Publication
31362952 | J:279690
 
First Author: Xu S
Year: 2019
Journal: Biol Open
Title: Discoidin domain receptor 1 deficiency in vascular smooth muscle cells leads to mislocalisation of N-cadherin contacts.
Volume: 8
Issue: 8
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Publication
32330138 | J:288096
First Author: Han T
Year: 2020
Journal: PLoS One
Title: Periostin interaction with discoidin domain receptor-1 (DDR1) promotes cartilage degeneration.
Volume: 15
Issue: 4
Pages: e0231501
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Protein
G3UXE5
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: true
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Protein
B0V2H8
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: true
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Protein
D6RII6
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: true
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Protein
Q62371
Organism: Mus musculus/domesticus
Length: 854  
Fragment?: false
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Protein
Q03146
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Protein
Q544T2
Organism: Mus musculus/domesticus
Length: 874  
Fragment?: false
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Protein
Q05BN5
Organism: Mus musculus/domesticus
Length: 891  
Fragment?: true
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Protein
O35407
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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