|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 247 out of 247 for Ddt

<< First    < Previous  |  Next >    Last >>
0.018s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
Q9Z277
Organism: Mus musculus/domesticus
Length: 1479  
Fragment?: false
•
•
•
•
•
Protein
G3UWZ0
Organism: Mus musculus/domesticus
Length: 1552  
Fragment?: false
•
•
•
•
•
Protein
A2AUY4
Organism: Mus musculus/domesticus
Length: 2123  
Fragment?: false
•
•
•
•
•
Protein
A2A655
Organism: Mus musculus/domesticus
Length: 2973  
Fragment?: false
•
•
•
•
•
Protein
A2A654
Organism: Mus musculus/domesticus
Length: 3036  
Fragment?: false
•
•
•
•
•
Protein
E5D6T0
Organism: Mus musculus/domesticus
Length: 2640  
Fragment?: false
•
•
•
•
•
Protein
E9Q6A7
Organism: Mus musculus/domesticus
Length: 2921  
Fragment?: false
•
•
•
•
•
Allele
Tg(CAG-Ddt)#Tashi | MGI:6771567
Name: transgene insertion, Tadamichi Shimizu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Protein
Q91YE5
Organism: Mus musculus/domesticus
Length: 1889  
Fragment?: false
•
•
•
•
•
Protein
E9Q374
Organism: Mus musculus/domesticus
Length: 1888  
Fragment?: false
•
•
•
•
•
Protein
A0A1W2P6X9
Organism: Mus musculus/domesticus
Length: 1890  
Fragment?: false
•
•
•
•
•
Protein
A0A5F8MPQ7
Organism: Mus musculus/domesticus
Length: 1889  
Fragment?: false
•
•
•
•
•
Protein
F8VPM0
Organism: Mus musculus/domesticus
Length: 1887  
Fragment?: false
•
•
•
•
•
Heritable Phenotypic Marker
MGI:99134 | xn
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
•
•
•
•
•
Publication
744482 | J:6099
First Author: Wallace ME
Year: 1978
Journal: Genet Res
Title: Inheritance and morphology of exencephaly, a neonatal lethal recessive with partial penetrance, in the house mouse.
Volume: 32
Issue: 2
Pages: 135-49
•
•
•
•
•
Publication
- | J:29023
 
First Author: Knights
Year: 1972
Journal: Mouse News Lett
Title: Hydrancephaly
Volume: 47
Pages: 24
•
•
•
•
•
Publication
- | J:13692
 
First Author: Wallace ME
Year: 1976
Journal: Mouse News Lett
Title: Exencephaly.
Volume: 55
Pages: 10
•
•
•
•
•
Publication
34105803 | J:309043
First Author: Yoshihisa Y
Year: 2021
Journal: FASEB J
Title: Overexpression of D-dopachrome tautomerase increases ultraviolet B irradiation-induced skin tumorigenesis in mice.
Volume: 35
Issue: 7
Pages: e21671
•
•
•
•
•
Protein Domain
IPR028942 | WHIM1_dom
Type: Domain
Description: WHIM1 is a conserved alpha helical motif that along with the WHIM2 and WHIM3 motifs, and the DDT domain comprise an alpha helical module found in diverse eukaryotic chromatin proteins [].Based on the Ioc3 structure, this module is inferred to interact with nucleosomal linker DNA and the SLIDE domain of ISWI proteins [, ]. The resulting complex forms a protein ruler that measures out the spacing between two adjacent nucleosomes []. The conserved basic residue in WHIM1 is involved in packing with the DDT motif. The module shows a great domain architectural diversity and is often combined with other modified histone peptide recognizing and DNA binding domains, some of which discriminate methylated DNA [].
•
•
•
•
•
Publication
21525927 | -
First Author: Yamada K
Year: 2011
Journal: Nature
Title: Structure and mechanism of the chromatin remodelling factor ISW1a.
Volume: 472
Issue: 7344
Pages: 448-53
•
•
•
•
•
Publication
22694359 | -
First Author: Li G
Year: 2012
Journal: Plant J
Title: Imitation Switch chromatin remodeling factors and their interacting RINGLET proteins act together in controlling the plant vegetative phase in Arabidopsis.
Volume: 72
Issue: 2
Pages: 261-70
•
•
•
•
•
Publication
23872538 | -
First Author: Sundaram S
Year: 2013
Journal: Plant Cell
Title: Gene networks and chromatin and transcriptional regulation of the phaseolin promoter in Arabidopsis.
Volume: 25
Issue: 7
Pages: 2601-17
•
•
•
•
•
Protein Domain
IPR044977 | RLT1/2/3
Type: Family
Description: The ISWI chromatin remodeling complexes are widely present in eukaryotic species. This entry represents the plant ISWI binding proteins, the DDT domain proteins, including RLT1 and RLT2 from Arabidopsis []. AtISWI physically interacts with RLTs, and this prevents plants from activating the vegetative-to-reproductive transition early by regulating several key genes that contribute to flower timing []. RLT2 may also be involved in the transcriptional regulation of endogenous seed genes [].
•
•
•
•
•
Publication
38175749 | J:344367
First Author: Marple T
Year: 2024
Journal: Cell Rep
Title: TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis.
Volume: 43
Issue: 1
Pages: 113637
•
•
•
•
•
Protein
Q3UK64
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: true
•
•
•
•
•
Publication
19734295 | -
First Author: Mukherjee K
Year: 2009
Journal: Mol Biol Evol
Title: A comprehensive classification and evolutionary analysis of plant homeobox genes.
Volume: 26
Issue: 12
Pages: 2775-94
•
•
•
•
•
Protein Domain
IPR028941 | WHIM2_dom
Type: Domain
Description: This entry represents the WHIM2 domain found in diverse eukaryotic chromatin proteins, such as animal BAZ/WAL and BPTF proteins, plant RLT, and yeast Itc1. This domain contains the D-TOX E motif (also known as the Williams-Beuren syndrome DDT (WSD) motif) that is conserved from yeasts to animals [, , ].WHIM2 domain is a conserved alpha helical motif that along with the WHIM1 and WHIM3 motifs, and the DDT domain comprise an alpha helical module found in diverse eukaryotic chromatin proteins []. Based on the Ioc3 structure, this module is inferred to interact with nucleosomal linker DNA and the SLIDE domain of ISWI proteins [, ]. The resulting complex forms a protein ruler that measures out the spacing between two adjacent nucleosomes []. The acidic residue from the GxD signature of WHIM2 is a major determinant of the interaction between the ISWI and WHIM motifs. The N-terminal portion of the WHIM2 motif also contacts the inter-nucleosomal linker DNA. The module shows a great domain architectural diversity and is often combined with other modified histone peptide recognizing and DNA binding domains, some of which discriminate methylated DNA [].
•
•
•
•
•
Publication
15640247 | J:96325
First Author: Banting GS
Year: 2005
Journal: Hum Mol Genet
Title: CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L.
Volume: 14
Issue: 4
Pages: 513-24
•
•
•
•
•
Publication
9087981 | J:41909
First Author: Simon ES
Year: 1997
Journal: Mov Disord
Title: Phenotypic heterogeneity and disease course in three murine strains with mutations in genes encoding for alpha 1 and beta glycine receptor subunits.
Volume: 12
Issue: 2
Pages: 221-8
•
•
•
•
•
Publication
28761001 | J:243839
First Author: Pilzecker B
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DNA damage tolerance in hematopoietic stem and progenitor cells in mice.
Volume: 114
Issue: 33
Pages: E6875-E6883
•
•
•
•
•
Publication
18840457 | J:143419
First Author: Han EH
Year: 2008
Journal: Toxicol Appl Pharmacol
Title: o,p'-DDT induces cyclooxygenase-2 gene expression in murine macrophages: Role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways.
Volume: 233
Issue: 2
Pages: 333-42
•
•
•
•
•
Publication
31251805 | J:280516
First Author: Pilzecker B
Year: 2019
Journal: Nucleic Acids Res
Title: DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.
Volume: 47
Issue: 14
Pages: 7163-7181
•
•
•
•
•
Publication
36214539 | J:336454
First Author: Woolbright BL
Year: 2023
Journal: J Pathol
Title: Role of MIF1/MIF2/CD74 interactions in bladder cancer.
Volume: 259
Issue: 1
Pages: 46-55
•
•
•
•
•
Protein
G3UZD1
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: true
•
•
•
•
•
Protein
G3UZ82
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
•
•
•
•
•
Protein
G3UXR5
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
•
•
•
•
•
Publication
22186017 | -
First Author: Aravind L
Year: 2012
Journal: Cell Cycle
Title: The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications.
Volume: 11
Issue: 1
Pages: 119-31
•
•
•
•
•
Publication
10385622 | -
First Author: Ito T
Year: 1999
Journal: Genes Dev
Title: ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly.
Volume: 13
Issue: 12
Pages: 1529-39
•
•
•
•
•
Publication
12192034 | -
First Author: Fyodorov DV
Year: 2002
Journal: Mol Cell Biol
Title: Binding of Acf1 to DNA involves a WAC motif and is important for ACF-mediated chromatin assembly.
Volume: 22
Issue: 18
Pages: 6344-53
•
•
•
•
•
Protein Domain
IPR013136 | WSTF_Acf1_Cbp146
Type: Domain
Description: ACF (for ATP-utilising chromatin assembly and remodeling factor) is a chromatin-remodeling complex that catalyzes the ATP-dependent assembly of periodic nucleosome arrays. This reaction utilises the energy of ATP hydrolysis by ISWI, the smaller of the two subunits of ACF. Acf1, the large subunit of ACF, is essential for the full activity of the complex. The WAC (WSTF/Acf1/cbp146) domain is an ~110-residue module present at the N-termini of Acf1-related proteins in a variety of organisms.It is found in association with other domains such as the bromodomain, the PHD-type zinc finger, DDT or WAKS. The DNA-binding region of Acf1 includes the WAC domain, which is necessary for the efficient binding of ACF complex to DNA. It seems probable that the WAC domain will be involved in DNA binding in other related factors [, ]. Some proteins known to contain a WAC domain are the Drosophila melanogaster (Fruit fly) ATP-dependent chromatin assembly factor large subunit Acf1, human WSTF (Williams syndrome transcription factor), mouse cbp146, yeast imitation switch two complex protein 1 (ITC1 or YGL133w), and yeast protein YPL216w.
•
•
•
•
•
Protein
Q3UXC9
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: false
•
•
•
•
•
Protein
Q6P1D9
Organism: Mus musculus/domesticus
Length: 892  
Fragment?: true
•
•
•
•
•
Protein
Q3USB1
Organism: Mus musculus/domesticus
Length: 543  
Fragment?: true
•
•
•
•
•
Protein
Q3V3T8
Organism: Mus musculus/domesticus
Length: 980  
Fragment?: true
•
•
•
•
•
Protein
Q8C8D1
Organism: Mus musculus/domesticus
Length: 718  
Fragment?: false
•
•
•
•
•
Protein
E9PWW9
Organism: Mus musculus/domesticus
Length: 1441  
Fragment?: false
•
•
•
•
•
Protein
Q3UJ04
Organism: Mus musculus/domesticus
Length: 998  
Fragment?: true
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom