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Search results 201 to 300 out of 328 for Dgat1

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Specimen Label: MH1749; Specimen C1932
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Specimen Label: MH1749; Specimen C1932
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Specimen Label: MH1749; Specimen C1932
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Image: MH1749; Specimen C1932
Specimen Label: MH1749; Specimen C1932
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Specimen Label: MH1749; Specimen C1932
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MH1749; Specimen C1932
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4427790
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422431
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MH1749; Specimen C1932
Detected: false
Specimen Num: 1
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Publication
18458083 | J:138119
First Author: Cao J
Year: 2008
Journal: J Biol Chem
Title: Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2.
Volume: 283
Issue: 27
Pages: 19049-57
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Publication
23583843 | J:202398
First Author: Clugston RD
Year: 2012
Journal: Biochim Biophys Acta
Title: Altered hepatic retinyl ester concentration and acyl composition in response to alcohol consumption.
Volume: 1831
Issue: 7
Pages: 1276-86
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Publication
12077311 | J:77354
First Author: Yen CL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase.
Volume: 99
Issue: 13
Pages: 8512-7
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Publication
20204375 | J:158707
First Author: Prevorsek Z
Year: 2010
Journal: Mamm Genome
Title: Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci.
Volume: 21
Issue: 3-4
Pages: 172-85
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Publication
19049983 | J:147912
First Author: Stone SJ
Year: 2009
Journal: J Biol Chem
Title: The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria.
Volume: 284
Issue: 8
Pages: 5352-61
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Publication
9789033 | J:44983
First Author: Cases S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis.
Volume: 95
Issue: 22
Pages: 13018-23
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Publication
23066022 | J:192630
First Author: Eichmann TO
Year: 2012
Journal: J Biol Chem
Title: Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.
Volume: 287
Issue: 49
Pages: 41446-57
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Publication
24186946 | J:204194
First Author: Wongsiriroj N
Year: 2014
Journal: J Lipid Res
Title: Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue.
Volume: 55
Issue: 1
Pages: 104-14
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Publication
32268121 | J:288898
First Author: Karagiannis F
Year: 2020
Journal: Immunity
Title: Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation.
Volume: 52
Issue: 4
Pages: 620-634.e6
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Publication
14722362 | J:88731
First Author: Welch CL
Year: 2004
Journal: Physiol Genomics
Title: Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain.
Volume: 17
Issue: 1
Pages: 48-59
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Publication
23988655 | J:210054
First Author: Dixon JL
Year: 2014
Journal: Biochim Biophys Acta
Title: Loss of β-carotene 15,15'-oxygenase in developing mouse tissues alters esterification of retinol, cholesterol and diacylglycerols.
Volume: 1841
Issue: 1
Pages: 34-43
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Publication
15181539 | J:90000
First Author: Stylianou IM
Year: 2004
Journal: Mamm Genome
Title: Genetic complexity of an obesity QTL ( Fob3) revealed by detailed genetic mapping.
Volume: 15
Issue: 6
Pages: 472-81
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Publication
25602705 | J:230265
 
First Author: Kim YK
Year: 2015
Journal: Arch Biochem Biophys
Title: Tissue- and sex-specific effects of β-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice.
Volume: 572
Pages: 11-8
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Publication
27731369 | J:259970
 
First Author: Segerer G
Year: 2016
Journal: Sci Rep
Title: An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.
Volume: 6
Pages: 35160
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Publication
18502258 | J:307827
First Author: Lindegaard ML
Year: 2008
Journal: Metabolism
Title: Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart.
Volume: 57
Issue: 6
Pages: 766-73
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Publication
27754788 | J:240750
First Author: Bose SK
Year: 2016
Journal: Endocrinology
Title: Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.
Volume: 157
Issue: 12
Pages: 4943-4960
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Publication
31693883 | J:299602
First Author: Mayeuf-Louchart A
Year: 2019
Journal: Cell Rep
Title: Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.
Volume: 29
Issue: 6
Pages: 1410-1418.e6
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Publication
22967998 | J:190524
First Author: Shalom-Barak T
Year: 2012
Journal: Dev Biol
Title: Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.
Volume: 372
Issue: 1
Pages: 143-55
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
22826105 | J:192662
First Author: Li T
Year: 2013
Journal: Transgenic Res
Title: Ectopic overexpression of porcine DGAT1 increases intramuscular fat content in mouse skeletal muscle.
Volume: 22
Issue: 1
Pages: 187-94
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Publication
30936184 | J:277715
First Author: Chitraju C
Year: 2019
Journal: J Lipid Res
Title: The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes.
Volume: 60
Issue: 6
Pages: 1112-1120
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HT Experiment
E-GEOD-26267 | Comparison of hepatic gene expression between short-term calorie restricted wild-type and Dgat1 deficient middle-aged female mice
Series Id: GSE26267
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
22493088 | -
First Author: Qi J
Year: 2012
Journal: J Lipid Res
Title: The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2.
Volume: 53
Issue: 6
Pages: 1106-16
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Publication
20040537 | -
First Author: Zhang M
Year: 2009
Journal: Plant Cell
Title: DGAT1 and PDAT1 acyltransferases have overlapping functions in Arabidopsis triacylglycerol biosynthesis and are essential for normal pollen and seed development.
Volume: 21
Issue: 12
Pages: 3885-901
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Publication
15834126 | -
First Author: Yen CL
Year: 2005
Journal: J Lipid Res
Title: The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters.
Volume: 46
Issue: 7
Pages: 1502-11
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Publication
15258194 | -
First Author: Ganji SH
Year: 2004
Journal: J Lipid Res
Title: Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells.
Volume: 45
Issue: 10
Pages: 1835-45
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Publication
17618857 | J:124005
First Author: Monetti M
Year: 2007
Journal: Cell Metab
Title: Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.
Volume: 6
Issue: 1
Pages: 69-78
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Allele
Dgat1<em1Smoc> | MGI:7289320
Name: diacylglycerol O-acyltransferase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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DO Term
DOID:0060778 | congenital diarrhea 7 with exudative enteropathy
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Publication
25858561 | J:249510
First Author: Kolwicz SC Jr
Year: 2015
Journal: Diabetes
Title: Enhancing Cardiac Triacylglycerol Metabolism Improves Recovery From Ischemic Stress.
Volume: 64
Issue: 8
Pages: 2817-27
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Allele
Tg(APOE-DGAT1)1Far | MGI:3720375
Name: transgene insertion 1, Bob Farese
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Fabp4-Dgat1)2Far | MGI:4418728
Name: transgene insertion 2, Robert V Farese
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Myh6-DGAT1)#Ijg | MGI:6099060
Name: transgene insertion, Ira J Goldberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Transgene
MGI:3720366 | Tg(APOE-DGAT1)1Far
Type: transgene
Organism: mouse, laboratory
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Publication
22628613 | J:186561
First Author: Liu L
Year: 2012
Journal: J Lipid Res
Title: Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice.
Volume: 53
Issue: 8
Pages: 1482-92
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Strain
MGI:4819519 | C57BL/6-Tg(APOE-DGAT1)1Far/Mmucd
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:5287423 | C57BL/6-Tg(Fabp4-Dgat1)2Far/J
Attribute String: transgenic, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Tg(APOE-DGAT1)1Far/?
Background: involves: C57BL/6NHsd
Zygosity: ot
Has Mutant Allele: true
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Publication
12401709 | J:107180
First Author: Chen HC
Year: 2002
Journal: Diabetes
Title: Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue.
Volume: 51
Issue: 11
Pages: 3189-95
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Publication
16106050 | -
First Author: Yen CL
Year: 2005
Journal: J Lipid Res
Title: A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters.
Volume: 46
Issue: 11
Pages: 2388-97
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Protein
Q8R3I2
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
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Protein
Q91V01
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
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Publication
32253259 | J:296120
     
First Author: Tanaka Y
Year: 2020
Journal: Gut
Title: LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover.
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Protein
Q8CHK3
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: false
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Protein
Q8BH98
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Protein
Q9JJJ7
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
P0C7A3
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
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Protein
Q5T1H3
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
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Protein
Q05CC9
Organism: Mus musculus/domesticus
Length: 404  
Fragment?: true
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Protein
A0A217FL69
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
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Protein
D3YU33
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Publication
16214399 | -
First Author: Orland MD
Year: 2005
Journal: Biochim Biophys Acta
Title: Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.
Volume: 1737
Issue: 1
Pages: 76-82
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Publication
10580283 | -
First Author: Routaboul JM
Year: 1999
Journal: Plant Physiol Biochem
Title: The TAG1 locus of Arabidopsis encodes for a diacylglycerol acyltransferase.
Volume: 37
Issue: 11
Pages: 831-840
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Publication
10601854 | -
First Author: Bouvier-Navé P
Year: 2000
Journal: Eur J Biochem
Title: Expression in yeast and tobacco of plant cDNAs encoding acyl CoA:diacylglycerol acyltransferase.
Volume: 267
Issue: 1
Pages: 85-96
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Publication
12114588 | -
First Author: Lu C
Year: 2002
Journal: Plant Physiol
Title: Arabidopsis mutants deficient in diacylglycerol acyltransferase display increased sensitivity to abscisic acid, sugars, and osmotic stress during germination and seedling development.
Volume: 129
Issue: 3
Pages: 1352-8
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Publication
20101470 | -
First Author: Li R
Year: 2010
Journal: Lipids
Title: DGAT1, DGAT2 and PDAT expression in seeds and other tissues of epoxy and hydroxy fatty acid accumulating plants.
Volume: 45
Issue: 2
Pages: 145-57
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Protein Domain
IPR004299 | MBOAT_fam
Type: Family
Description: The MBOAT (membrane bound O-acyl transferase) family of membrane proteins contains a variety of acyltransferase enzymes. A conserved histidine has been suggested to be the active site residue []. The structure of MBOAT has been revealed [].This family includes Diacylglycerol O-acyltransferase 1 (DGAT1) and Lysophospholipid acyltransferase 7 (MBOAT7) from humans. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates []. It also functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders []. MBOAT7 participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation [].
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Protein Domain
IPR027251 | Diacylglycerol_acylTrfase1
Type: Family
Description: Diacylglycerol O-acyltransferase 1 (DGAT1) catalyses the final step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In plants, diacylglycerol O-acyltransferase 1 (DGAT1, TAG1) is a major enzyme for oil accumulation in seeds. It has complementary functions with PDAT1 acyltransferase that are essential for triacylglycerol synthesis and normal development of both seeds and pollen [, , , , ].In mammals, DGAT1 is a multifunctional acyltransferase capable of synthesizing diacylglycerol, retinyl, and wax esters in addition to triacylglycerol []. In liver, it plays a role in esterifying exogenous fatty acids to glycerol []. It also functions as the major acyl-CoA retinol acyltransferase in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders [].
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