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Search results 201 to 300 out of 344 for Dlg2

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Type Details Score
Publication
19455133 | J:152628
 
First Author: Fernández E
Year: 2009
Journal: Mol Syst Biol
Title: Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.
Volume: 5
Pages: 269
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Publication
27178982 | J:234018
   
First Author: Singh S
Year: 2016
Journal: Elife
Title: Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.
Volume: 5
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Publication
27480238 | J:241274
 
First Author: Lie E
Year: 2016
Journal: Nat Commun
Title: SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.
Volume: 7
Pages: 12328
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Publication
28671696 | J:249721
First Author: Li J
Year: 2017
Journal: Nat Neurosci
Title: Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
Volume: 20
Issue: 8
Pages: 1150-1161
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Publication
17114649 | J:187362
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
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Publication
24613359 | J:211830
First Author: Um JW
Year: 2014
Journal: Cell Rep
Title: Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Volume: 6
Issue: 6
Pages: 1096-1109
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
28724449 | -
First Author: Reggiani C
Year: 2017
Journal: Genome Med
Title: Novel promoters and coding first exons in DLG2 linked to developmental disorders and intellectual disability.
Volume: 9
Issue: 1
Pages: 67
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Protein
A0A240F9Y4
Organism: Mus musculus/domesticus
Length: 21  
Fragment?: true
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Protein
A0A240F9Y3
Organism: Mus musculus/domesticus
Length: 26  
Fragment?: true
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Publication
32356104 | J:294511
First Author: Yang CH
Year: 2020
Journal: Diabetologia
Title: E2f8 and Dlg2 genes have independent effects on impaired insulin secretion associated with hyperglycaemia.
Volume: 63
Issue: 7
Pages: 1333-1348
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Protein Coding Gene
MGI:1858257 | Mpp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20054121 | -
First Author: Fiorentini M
Year: 2009
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun
Title: Structure of the first PDZ domain of human PSD-93.
Volume: 65
Issue: Pt 12
Pages: 1254-7
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Protein Domain
IPR035759 | DLG2_SH3
Type: Domain
Description: DLG2 (also known as PSD-93) is a scaffolding protein that clusters at synapses and plays an important role in synaptic development and plasticity. The DLG2 delta isoform binds inwardly rectifying potassium Kir2 channels, which determine resting membrane potential in neurons. It regulates the spatial and temporal distribution of Kir2 channels within neuronal membranes []. DLG2 is a member of the MAGUK (membrane-associated guanylate kinase) protein family, which is characterized by the presence of a core of three domains: PDZ, SH3, and guanylate kinase (GuK). The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain []. DLG2 contains three PDZ domains [].
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Publication
21498811 | -
First Author: Zheng CY
Year: 2011
Journal: Neuroscientist
Title: MAGUKs, synaptic development, and synaptic plasticity.
Volume: 17
Issue: 5
Pages: 493-512
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Publication
27902448 | J:259223
First Author: Shahani N
Year: 2016
Journal: Sci Signal
Title: RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.
Volume: 9
Issue: 454
Pages: ra111
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Publication
8824795 | J:59609
First Author: Smith SA
Year: 1996
Journal: Genomics
Title: Isolation of a gene (DLG3) encoding a second member of the discs-large family on chromosome 17q12-q21.
Volume: 31
Issue: 2
Pages: 145-50
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Publication
30210525 | J:294638
 
First Author: Colville AM
Year: 2018
Journal: Front Genet
Title: Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders.
Volume: 9
Pages: 300
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Publication
8155583 | -
First Author: Woods DF
Year: 1993
Journal: Mech Dev
Title: ZO-1, DlgA and PSD-95/SAP90: homologous proteins in tight, septate and synaptic cell junctions.
Volume: 44
Issue: 2-3
Pages: 85-9
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Protein Domain
IPR020590 | Guanylate_kinase_CS
Type: Conserved_site
Description: Guanylate kinase () (GK) []catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. In prokaryotes (such as Escherichia coli), lower eukaryotes(such as yeast) and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids. GK has been shown [, , ]to be structurally similar to protein A57R (or SalG2R) from various strains of Vaccinia virus.Proteins containing one or more copies of the DHR domain, an SH3 domain as well as a C-terminal GK-like domain, are collectively termed MAGUKs (membrane-associated guanylate kinase homologues) [], andinclude Drosophila lethal(1)discs large-1 tumor suppressor protein (gene dlg1); mammalian tight junction protein Zo-1; a family of mammalian synaptic proteins that seem to interact with the cytoplasmic tail of NMDA receptor subunits (SAP90/PSD-95, CHAPSYN-110/PSD-93, SAP97/DLG1 and SAP102); vertebrate 55kDa erythrocyte membrane protein (p55); Caenorhabditis elegans protein lin-2; rat protein CASK; and human proteins DLG2 and DLG3. There is an ATP-binding site (P-loop) in the N-terminal section of GK, which is not conserved in the GK-like domain of the above proteins. However these proteins retain the residues known, in GK, to be involved in the binding of GMP.This signature pattern covers a highly conserved region that contains two arginine and a tyrosine which are involved in GMP-binding.
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Protein Domain
IPR008144 | Guanylate_kin-like_dom
Type: Domain
Description: Guanylate kinase () (GK) []catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. In prokaryotes (such as Escherichia coli), lower eukaryotes(such as yeast) and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids. GK has been shown [, , ]to be structurally similar to protein A57R (or SalG2R) from various strains of Vaccinia virus.Proteins containing one or more copies of the DHR domain, an SH3 domain as well as a C-terminal GK-like domain, are collectively termed MAGUKs (membrane-associated guanylate kinase homologues) [], andinclude Drosophila lethal(1)discs large-1 tumor suppressor protein (gene dlg1); mammalian tight junction protein Zo-1; a family of mammalian synaptic proteins that seem to interact with the cytoplasmic tail of NMDA receptor subunits (SAP90/PSD-95, CHAPSYN-110/PSD-93, SAP97/DLG1 and SAP102); vertebrate 55kDa erythrocyte membrane protein (p55); Caenorhabditis elegans protein lin-2; rat protein CASK; and human proteins DLG2 and DLG3.There is an ATP-binding site (P-loop) in the N-terminal section of GK, which is not conserved in the GK-like domain of the above proteins. However these proteins retain the residues known, in GK, to be involved in the binding of GMP.
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Publication
1310897 | -
First Author: Bryant PJ
Year: 1992
Journal: Cell
Title: A major palmitoylated membrane protein of human erythrocytes shows homology to yeast guanylate kinase and to the product of a Drosophila tumor suppressor gene.
Volume: 68
Issue: 4
Pages: 621-2
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Publication
8097461 | -
First Author: Zschocke PD
Year: 1993
Journal: Eur J Biochem
Title: Purification and sequence determination of guanylate kinase from pig brain.
Volume: 213
Issue: 1
Pages: 263-9
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Publication
1314905 | -
First Author: Stehle T
Year: 1992
Journal: J Mol Biol
Title: Refined structure of the complex between guanylate kinase and its substrate GMP at 2.0 A resolution.
Volume: 224
Issue: 4
Pages: 1127-41
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Publication
1329277 | -
First Author: Goebl MG
Year: 1992
Journal: Trends Biochem Sci
Title: Is the erythrocyte protein p55 a membrane-bound guanylate kinase?
Volume: 17
Issue: 3
Pages: 99
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Protein
Q91XM9
Organism: Mus musculus/domesticus
Length: 852  
Fragment?: false
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Protein
A0A571BEK3
Organism: Mus musculus/domesticus
Length: 901  
Fragment?: false
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Protein
E9Q2L2
Organism: Mus musculus/domesticus
Length: 870  
Fragment?: false
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Protein
A0A571BEZ4
Organism: Mus musculus/domesticus
Length: 919  
Fragment?: false
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Protein
A0A338P6J0
Organism: Mus musculus/domesticus
Length: 994  
Fragment?: false
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Protein
D3YUZ8
Organism: Mus musculus/domesticus
Length: 755  
Fragment?: false
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Protein
A0A2L2P590
Organism: Mus musculus/domesticus
Length: 843  
Fragment?: false
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Protein
Q64520
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
E9Q7K1
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Protein
F7CD87
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: true
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Protein
Q8BP37
Organism: Mus musculus/domesticus
Length: 175  
Fragment?: true
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Protein
Q9D3X0
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
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Protein
Q3TNZ0
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
B1AUH6
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: false
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Protein
Q6RHR9
Organism: Mus musculus/domesticus
Length: 1471  
Fragment?: false
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Protein
Q9WVQ1
Organism: Mus musculus/domesticus
Length: 1275  
Fragment?: false
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Protein
Q9EQJ9
Organism: Mus musculus/domesticus
Length: 1476  
Fragment?: false
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Protein
Q4H4B4
Organism: Mus musculus/domesticus
Length: 1470  
Fragment?: false
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Protein
A0A0G2JE00
Organism: Mus musculus/domesticus
Length: 1414  
Fragment?: false
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Protein
Q3TQ86
Organism: Mus musculus/domesticus
Length: 1181  
Fragment?: true
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Protein
G5E8T6
Organism: Mus musculus/domesticus
Length: 1476  
Fragment?: false
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Protein
A0A0G2JEG6
Organism: Mus musculus/domesticus
Length: 1400  
Fragment?: false
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Protein
Q91VJ0
Organism: Mus musculus/domesticus
Length: 356  
Fragment?: false
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Protein
Q4H4B5
Organism: Mus musculus/domesticus
Length: 1235  
Fragment?: false
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Protein
A0A2L2P595
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
B9EKC0
Organism: Mus musculus/domesticus
Length: 1280  
Fragment?: false
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Protein
A0A0N4SUZ0
Organism: Mus musculus/domesticus
Length: 1280  
Fragment?: false
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Protein
A0A0R4J0S6
Organism: Mus musculus/domesticus
Length: 1171  
Fragment?: false
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Protein
Q5DTM1
Organism: Mus musculus/domesticus
Length: 1125  
Fragment?: true
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Protein
Q4VBG2
Organism: Mus musculus/domesticus
Length: 1115  
Fragment?: true
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Protein
Q9D5S7
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Protein
A0A2I3BQA5
Organism: Mus musculus/domesticus
Length: 1340  
Fragment?: false
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Protein
Q8BVD5
Organism: Mus musculus/domesticus
Length: 576  
Fragment?: false
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Protein
Q9WV34
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
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Protein
O88910
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Protein
Q9JLB0
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Protein
Q9JLB2
Organism: Mus musculus/domesticus
Length: 675  
Fragment?: false
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Protein
P70175
Organism: Mus musculus/domesticus
Length: 849  
Fragment?: false
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Protein
P70290
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false
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Protein
Q62108
Organism: Mus musculus/domesticus
Length: 724  
Fragment?: false
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Protein
Q811D0
Organism: Mus musculus/domesticus
Length: 905  
Fragment?: false
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Protein
Q6P7F1
Organism: Mus musculus/domesticus
Length: 635  
Fragment?: false
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Protein
A0A087WQU9
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom