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Search results 201 to 300 out of 345 for Dmpk

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Type Details Score
Protein
P54265-8
Organism: Mus musculus/domesticus
Length: 632  
Fragment?: false
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Protein
P54265-3
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: false
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Protein
P54265-9
Organism: Mus musculus/domesticus
Length: 627  
Fragment?: false
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Publication
26304544 | J:233658
First Author: Koscianska E
Year: 2015
Journal: Nucleic Acids Res
Title: Cooperation meets competition in microRNA-mediated DMPK transcript regulation.
Volume: 43
Issue: 19
Pages: 9500-18
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Publication
14734627 | J:88629
First Author: Storbeck CJ
Year: 2004
Journal: Hum Mol Genet
Title: Inhibition of myogenesis in transgenic mice expressing the human DMPK 3'-UTR.
Volume: 13
Issue: 6
Pages: 589-600
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Allele
Dmpk<em1Smoc> | MGI:7289361
Name: dystrophia myotonica-protein kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Dmpk<tm1(DMPK)Smoc> | MGI:7786848
Name: dystrophia myotonica-protein kinase; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Protein
P54265
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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Protein
P54265-4
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Protein
P54265-2
Organism: Mus musculus/domesticus
Length: 602  
Fragment?: false
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Protein
P54265-7
Organism: Mus musculus/domesticus
Length: 557  
Fragment?: false
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Protein
P54265-10
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: false
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Allele
Tg(CAG-DMPK*)1323Coop | MGI:5426792
Name: transgene insertion 1323, Thomas A Cooper
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(DMWD,DMPK*,SIX5)328Ggo | MGI:5523461
Name: transgene insertion 328, Genevieve Gourdon
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(DMWD,DMPK*,SIX5)1177Ggo | MGI:5523466
Name: transgene insertion 1177, Genevieve Gourdon
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6475139 | C57BL/6JSmoc-Dmpk<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7788677 | C57BL/6JSmoc-Dmpk<tm1(DMPK)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Tg(ACTA1-cre/ERT2)97.16Mtz/? Tg(CAG-DMPK*)1323Coop/?
Background: involves: FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(DMWD,DMPK*,SIX5)1177Ggo/Tg(DMWD,DMPK*,SIX5)1177Ggo
Background: involves: C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: A1cf/A1cf<+> Tg(CAG-DMPK*)1323Coop/?
Background: involves: FVB
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE228314 | Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1 [mouse]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Dmpk<tm1Rdd> | MGI:2182402
Name: dystrophia myotonica-protein kinase; targeted mutation 1, Sita Reddy
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(DM15)26Bew | MGI:3054417
Name: transgene insertion 26, Be Wieringa
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Myh6-rtTA)8585Jam | MGI:3712947
Name: transgene insertion 8585, John A McDonald
Allele Type: Transgenic
Attribute String: Transactivator
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Allele
Tg(HSA*LR)41Cath | MGI:3763903
Name: transgene insertion 41, Charles A Thornton
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(HSA*LR)20aCath | MGI:3763906
Name: transgene insertion 20a, Charles A Thornton
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(HSA*LR)20bCath | MGI:3763907
Name: transgene insertion 20b, Charles A Thornton
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(HSA*LR)21Cath | MGI:3763908
Name: transgene insertion 21, Charles A Thornton
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(HSA*LR)32aCath | MGI:3763909
Name: transgene insertion 32a, Charles A Thornton
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(HSA*LR)32bCath | MGI:3763910
Name: transgene insertion 32b, Charles A Thornton
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(DMPK/tetO-EGFP/DMPK)5-313Masm | MGI:3813454
Name: transgene insertion 5-313, Mani S Mahadevan
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence, Reporter
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Allele
Tg(tetO-CUGBP1)3413Coop | MGI:4438033
Name: transgene insertion 3413, Thomas A Cooper
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(Ckm-CUGBP1)1039Coop | MGI:5427873
Name: transgene insertion 1039, Thomas A Cooper
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
28369378 | J:242845
First Author: Wang PY
Year: 2017
Journal: Hum Mol Genet
Title: Reduced cytoplasmic MBNL1 is an early event in a brain-specific mouse model of myotonic dystrophy.
Volume: 26
Issue: 12
Pages: 2247-2257
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Publication
36935893 | J:337484
 
First Author: Golini E
Year: 2023
Journal: Front Behav Neurosci
Title: Excessive rest time during active phase is reliably detected in a mouse model of myotonic dystrophy type 1 using home cage monitoring.
Volume: 17
Pages: 1130055
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Publication
36922901 | J:335020
First Author: Wang PY
Year: 2023
Journal: Acta Neuropathol Commun
Title: Loss of MBNL1-mediated retrograde BDNF signaling in the myotonic dystrophy brain.
Volume: 11
Issue: 1
Pages: 44
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Publication
34025359 | J:321267
 
First Author: González-Barriga A
Year: 2021
Journal: Front Cell Neurosci
Title: Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1.
Volume: 15
Pages: 662035
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Publication
23180777 | J:196337
First Author: Panaite PA
Year: 2013
Journal: Dis Model Mech
Title: Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy.
Volume: 6
Issue: 3
Pages: 622-31
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Publication
23209425 | J:194171
First Author: Huguet A
Year: 2012
Journal: PLoS Genet
Title: Molecular, physiological, and motor performance defects in DMSXL mice carrying >1,000 CTG repeats from the human DM1 locus.
Volume: 8
Issue: 11
Pages: e1003043
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Allele
Mbnl1<tm1Sws> | MGI:3052922
Name: muscleblind like splicing regulator 1; targeted mutation 1, Maurice W Swanson
Allele Type: Targeted
Attribute String: Null/knockout
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Transgene
MGI:3054421 | Tg(DM15)26Bew
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3763888 | Tg(HSA*LR)41Cath
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3763889 | Tg(HSA*LR)20aCath
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3763890 | Tg(HSA*LR)20bCath
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3763892 | Tg(HSA*LR)21Cath
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3763893 | Tg(HSA*LR)32aCath
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3763895 | Tg(HSA*LR)32bCath
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:3813453 | Tg(DMPK/tetO-EGFP/DMPK)5-313Masm
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4438034 | Tg(tetO-CUGBP1)3413Coop
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5426789 | Tg(CAG-DMPK*)1323Coop
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5427872 | Tg(Ckm-CUGBP1)1039Coop
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5523457 | Tg(DMWD,DMPK*,SIX5)328Ggo
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5523465 | Tg(DMWD,DMPK*,SIX5)1177Ggo
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(DM15)26Bew/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dmpk/Dmpk
Background: involves: 129S2/SvPas * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dmpk/Dmpk<+>
Background: involves: 129S2/SvPas * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HSA*LR)20aCath/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HSA*LR)20bCath/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HSA*LR)32aCath/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HSA*LR)32bCath/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HSA*LR)41Cath/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(HSA*LR)21Cath/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(DMPK/tetO-EGFP/DMPK)5-313Masm/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-rtTA)8585Jam/? Tg(tetO-CUGBP1)3413Coop/?
Background: involves: FVB * FVB/N * FVB/NTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ckm-CUGBP1)1039Coop/?
Background: FVB-Tg(Ckm-CUGBP1)1039Coop
Zygosity: ot
Has Mutant Allele: true
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DO Term
DOID:11722 | myotonic dystrophy type 1
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Publication
12727892 | J:83373
First Author: Savouret C
Year: 2003
Journal: EMBO J
Title: CTG repeat instability and size variation timing in DNA repair-deficient mice.
Volume: 22
Issue: 9
Pages: 2264-73
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Publication
17823658 | J:127391
First Author: Wang GS
Year: 2007
Journal: J Clin Invest
Title: Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy.
Volume: 117
Issue: 10
Pages: 2802-11
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Publication
25799359 | J:229190
First Author: González-Barriga A
Year: 2015
Journal: PLoS One
Title: Cell membrane integrity in myotonic dystrophy type 1: implications for therapy.
Volume: 10
Issue: 3
Pages: e0121556
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Publication
24315854 | J:208825
First Author: Lassiter RN
Year: 2014
Journal: Dev Biol
Title: Signaling mechanisms controlling cranial placode neurogenesis and delamination.
Volume: 389
Issue: 1
Pages: 39-49
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Allele
Tg(DMPK*,DMWD,RSPH6A)24Lutzy | MGI:6357826
Name: transgene insertion 24, Cathy Lutz
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
16552576 | J:174180
First Author: Foiry L
Year: 2006
Journal: Hum Genet
Title: Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
Volume: 119
Issue: 5
Pages: 520-6
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Publication
22371589 | J:182237
First Author: Lee JE
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1.
Volume: 109
Issue: 11
Pages: 4221-6
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Publication
21044947 | J:166707
First Author: López Castel A
Year: 2011
Journal: Hum Mol Genet
Title: Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues.
Volume: 20
Issue: 1
Pages: 1-15
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Publication
21173221 | J:169017
First Author: Zu T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Non-ATG-initiated translation directed by microsatellite expansions.
Volume: 108
Issue: 1
Pages: 260-5
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Publication
37811496 | J:347845
 
First Author: Ginjupalli VKM
Year: 2023
Journal: Front Physiol
Title: Electrophysiological basis of cardiac arrhythmia in a mouse model of myotonic dystrophy type 1.
Volume: 14
Pages: 1257682
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Publication
14701736 | J:87575
First Author: Savouret C
Year: 2004
Journal: Mol Cell Biol
Title: MSH2-dependent germinal CTG repeat expansions are produced continuously in spermatogonia from DM1 transgenic mice.
Volume: 24
Issue: 2
Pages: 629-37
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Publication
17411343 | J:121539
First Author: Gomes-Pereira M
Year: 2007
Journal: PLoS Genet
Title: CTG trinucleotide repeat "big jumps": large expansions, small mice.
Volume: 3
Issue: 4
Pages: e52
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Publication
25211016 | J:222519
First Author: Klinck R
Year: 2014
Journal: PLoS One
Title: RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.
Volume: 9
Issue: 9
Pages: e107324
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Allele
Tg(tetO-DMPK*)A2352Coop | MGI:6158679
Name: transgene insertion A2352, Thomas A Cooper
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Strain
MGI:6388738 | C57BL/6J-Tg(DMPK*,DMWD,RSPH6A)24Lutzy/77J
Attribute String: coisogenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(DMWD,DMPK*,SIX5)328Ggo/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(DMWD,DMPK*,SIX5)1177Ggo/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(DMWD,DMPK*,SIX5)328Ggo/Tg(DMWD,DMPK*,SIX5)328Ggo
Background: involves: 129 * C57BL/6 * DBA/2 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Publication
25168381 | J:216510
First Author: Gladman JT
Year: 2015
Journal: Hum Mol Genet
Title: NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.
Volume: 24
Issue: 1
Pages: 251-64
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Publication
18084293 | J:131302
First Author: Yadava RS
Year: 2008
Journal: Nat Genet
Title: RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression.
Volume: 40
Issue: 1
Pages: 61-8
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Publication
32109384 | J:286588
First Author: Misra C
Year: 2020
Journal: Dev Cell
Title: Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy.
Volume: 52
Issue: 6
Pages: 748-763.e6
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Publication
31754023 | J:287840
First Author: Bargiela A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Increased Muscleblind levels by chloroquine treatment improve myotonic dystrophy type 1 phenotypes in in vitro and in vivo models.
Volume: 116
Issue: 50
Pages: 25203-25213
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Publication
28658620 | J:254355
First Author: Sicot G
Year: 2017
Journal: Cell Rep
Title: Downregulation of the Glial GLT1 Glutamate Transporter and Purkinje Cell Dysfunction in a Mouse Model of Myotonic Dystrophy.
Volume: 19
Issue: 13
Pages: 2718-2729
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Publication
19436705 | J:149536
First Author: Tomé S
Year: 2009
Journal: PLoS Genet
Title: MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.
Volume: 5
Issue: 5
Pages: e1000482
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Publication
26908607 | J:231444
First Author: Gudde AE
Year: 2016
Journal: Hum Mol Genet
Title: A low absolute number of expanded transcripts is involved in myotonic dystrophy type 1 manifestation in muscle.
Volume: 25
Issue: 8
Pages: 1648-62
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Publication
10767343 | J:168896
First Author: Seznec H
Year: 2000
Journal: Hum Mol Genet
Title: Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability.
Volume: 9
Issue: 8
Pages: 1185-94
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Strain
MGI:7256932 | STOCK Tg(tetO-DMPK*)A2352Coop Tg(Myl1-rtTA2S*M2)1Lach/J
Attribute String: mutant stock, transgenic
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Strain
MGI:6158681 | FVB/NJ-Tg(tetO-DMPK*)A2352Coop/J
Attribute String: transgenic, mutant strain, coisogenic
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Publication
10970838 | J:114763
First Author: Miller JW
Year: 2000
Journal: EMBO J
Title: Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.
Volume: 19
Issue: 17
Pages: 4439-48
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Publication
10802667 | J:61882
First Author: Klesert TR
Year: 2000
Journal: Nat Genet
Title: Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy.
Volume: 25
Issue: 1
Pages: 105-9
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Publication
35567413 | J:334586
First Author: Lee KY
Year: 2022
Journal: Hum Mol Genet
Title: Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy.
Volume: 31
Issue: 18
Pages: 3144-3160
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Publication
23901116 | J:200683
First Author: Gao Z
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy.
Volume: 110
Issue: 33
Pages: 13570-5
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Publication
22427994 | J:224126
First Author: Suenaga K
Year: 2012
Journal: PLoS One
Title: Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain.
Volume: 7
Issue: 3
Pages: e33218
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