| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:6755520 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318591 |
| Pattern: |
Uniform |
| Stage: |
TS01 |
| Assay Id: |
MGI:6755544 |
| Age: |
embryonic day 0.5 |
| Image: |
1E PN4 |
| Note: |
Expression evenly distributed across cells at all stages, except for at the 2-cell stage. |
| Specimen Label: |
1E PN4 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755521 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318653 |
| Pattern: |
Not Specified |
| Stage: |
TS03 |
| Assay Id: |
MGI:6755543 |
| Age: |
embryonic day 2.5 |
| Image: |
1D 8-c |
|
| Specimen Label: |
1D 8-c |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755520 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:318653 |
| Pattern: |
Uniform |
| Stage: |
TS03 |
| Assay Id: |
MGI:6755544 |
| Age: |
embryonic day 2.5 |
| Image: |
1E 8-c |
| Note: |
Expression evenly distributed across cells at all stages, except for at the 2-cell stage. |
| Specimen Label: |
1E 8-c |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755521 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360354 |
| Pattern: |
Not Specified |
| Stage: |
TS04 |
| Assay Id: |
MGI:6755543 |
| Age: |
embryonic day 3.5 |
| Image: |
1D blastocyst |
|
| Specimen Label: |
1D blastocyst |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755520 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360354 |
| Pattern: |
Uniform |
| Stage: |
TS04 |
| Assay Id: |
MGI:6755544 |
| Age: |
embryonic day 3.5 |
| Image: |
1E blastocyst |
| Note: |
Expression evenly distributed across cells at all stages, except for at the 2-cell stage. |
| Specimen Label: |
1E blastocyst |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Robust expression in ventricular and subventricular zones. |
| Specimen Label: |
1C eIF4E1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
1C (Pax6) |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression localized to punctate cytoplasmic granules in radial precursors expressing Pax6. |
| Specimen Label: |
1C (Unc5d) |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression localized to punctate cytoplasmic granules. |
| Specimen Label: |
1D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Authors report expession in same cells as Eif4enif1. |
| Specimen Label: |
4B eIF4E1 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression colocalized with Eif4enif1 in subpopulation of punctate cytoplasmic foci in radial precursor cell bodies. |
| Specimen Label: |
4B eIF4E1 (left) |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564031 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564065 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression colocalized with Eif4enif1 in apical endfeet adjacent to ventricle. |
| Specimen Label: |
4B eIF4E1 (right) |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755521 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3575528 |
| Pattern: |
Uniform |
| Stage: |
TS28 |
| Assay Id: |
MGI:6755543 |
| Age: |
postnatal adult |
| Image: |
1D Ooc |
| Note: |
Expression evenly distributed across the oocytes. |
| Specimen Label: |
1D Ooc |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755520 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3575528 |
| Pattern: |
Uniform |
| Stage: |
TS28 |
| Assay Id: |
MGI:6755544 |
| Age: |
postnatal adult |
| Image: |
1E Ooc |
| Note: |
Expression evenly distributed across cells at all stages, except for at the 2-cell stage. |
| Specimen Label: |
1E Ooc |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755521 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
| Pattern: |
Regionally restricted |
| Stage: |
TS02 |
| Assay Id: |
MGI:6755543 |
| Age: |
embryonic day 1.0 |
| Image: |
1D 2-c |
| Note: |
Accumulation of expression within nucleolus precursor bodies (NPB). |
| Specimen Label: |
1D 2-c |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6755520 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-09-01 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160362 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:6755544 |
| Age: |
embryonic day 1.0 |
| Image: |
1E 2-c |
|
| Specimen Label: |
1E 2-c |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
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Protein translation rate determines neocortical neuron fate. |
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Impairment of serine transport across the blood-brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction. |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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•
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•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
62
 |
| Fragment?: |
true |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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2014 |
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Database Release |
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Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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BMC Dev Biol |
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Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. |
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Kidney Int |
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Genome Res |
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Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
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GemPharmatech |
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2020 |
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GemPharmatech Website. |
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The Gene Ontology Consortium |
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2014 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Proc Natl Acad Sci U S A |
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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
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2002 |
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Toronto Centre for Phenogenomics |
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Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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GOA curators |
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2016 |
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| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
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Database Download |
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Mouse Gene Trap Data Load from dbGSS |
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Nature |
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The Gene Ontology Consortium |
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2010 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Mouse Genome Informatics Computational Sequence to Gene Associations |
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Shanghai Model Organisms Center |
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2017 |
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MGI Direct Data Submission |
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Allen Brain Atlas: mouse riboprobes |
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Entrez Gene Load |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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Helmholtz Zentrum Muenchen GmbH |
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MGI Direct Data Submission |
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2024 |
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Cell Rep |
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Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders. |
| Volume: |
43 |
| Issue: |
12 |
| Pages: |
114997 |
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•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; transgene insertion 2397E-1a3, Paul Overbeek |
| Allele Type: |
Transgenic |
| Attribute String: |
Reporter |
|
•
•
•
•
•
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| Publication |
| First Author: |
Sun W |
| Year: |
2021 |
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Genes Dev |
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Transcriptional regulation of the rat eIF4E gene in cardiac muscle cells: the role of specific elements in the promoter region. |
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Proc Natl Acad Sci U S A |
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ELAVL1 regulates alternative splicing of eIF4E transporter to promote postnatal angiogenesis. |
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| Year: |
2021 |
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Cancer Discov |
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MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression. |
| Volume: |
11 |
| Issue: |
5 |
| Pages: |
1228-1247 |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuroguidin, EIF4E binding protein; wild type |
| Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7564033 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-12-06 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:7564070 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression colocalized with Eif4e in apical endfeet adjacent to ventricle. |
| Specimen Label: |
4B 4E-T (right) |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|