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Search results 201 to 273 out of 273 for Epx

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Type Details Score
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
9256347 | J:42032
First Author: Branford WW
Year: 1997
Journal: Mech Dev
Title: Spx1, a novel X-linked homeobox gene expressed during spermatogenesis.
Volume: 65
Issue: 1-2
Pages: 87-98
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Publication
9245514 | J:42272
First Author: Li Y
Year: 1997
Journal: Dev Biol
Title: Esx1, a novel X chromosome-linked homeobox gene expressed in mouse extraembryonic tissues and male germ cells.
Volume: 188
Issue: 1
Pages: 85-95
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Publication
10611245 | -
First Author: Yan YT
Year: 2000
Journal: Mol Cell Biol
Title: A novel PF/PN motif inhibits nuclear localization and DNA binding activity of the ESX1 homeoprotein.
Volume: 20
Issue: 2
Pages: 661-71
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Allele
Epx<em1Smoc> | MGI:7263390
Name: eosinophil peroxidase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Epx<em3(cre)Smoc> | MGI:6514733
Name: eosinophil peroxidase; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout, Recombinase
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Strain
MGI:6428599 | C57BL/6JSmoc-Epx<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6475209 | C57BL/6JSmoc-Epx<em3(cre)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
7068848 | -
First Author: Locksley RM
Year: 1982
Journal: J Clin Invest
Title: Role for endogenous and acquired peroxidase in the toxoplasmacidal activity of murine and human mononuclear phagocytes.
Volume: 69
Issue: 5
Pages: 1099-111
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Publication
6281334 | -
First Author: Henderson WR
Year: 1982
Journal: J Immunol
Title: Eosinophil peroxidase-mediated inactivation of leukotrienes B4, C4, and D4.
Volume: 128
Issue: 6
Pages: 2609-13
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Publication
6987310 | -
First Author: Henderson WR
Year: 1980
Journal: J Immunol
Title: Binding of eosinophil peroxidase to mast cell granules with retention of peroxidatic activity.
Volume: 124
Issue: 3
Pages: 1383-8
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Publication
12208372 | -
First Author: Aldridge RE
Year: 2002
Journal: Free Radic Biol Med
Title: Eosinophil peroxidase produces hypobromous acid in the airways of stable asthmatics.
Volume: 33
Issue: 6
Pages: 847-56
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Publication
10811853 | -
First Author: Wu W
Year: 2000
Journal: J Clin Invest
Title: Eosinophils generate brominating oxidants in allergen-induced asthma.
Volume: 105
Issue: 10
Pages: 1455-63
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Protein Domain
IPR029599 | EPX/EPO
Type: Family
Description: Eosinophil peroxidase (EPX or EPO) is an eosinophil-derived granule protein that utilises H2O2 as an oxidising substrate to generate potent oxidising species. This mechanism is used by eosinophils to kill parasites and microbes [, ]. Besides using bromide as substrates to generate hypobromite (hypobromous acid), EPX can also oxidise thiocyanate (SCN-) ions to generate HOSCN-, which may induce the prothrombotic and proinflammatory endothelial and endocardial phenotypes responsible for thrombotic complications in the hypereosinophilic syndrome (HES) []. EPX is involved in both anti-inflammatory and pro-inflammatory activities [, ]. It may also play an important role through the production of reactive brominating species in asthma [, ]. It is required for eosinophilopoiesis in mice [].
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Publication
24802755 | -
First Author: Acharya KR
Year: 2014
Journal: J Biol Chem
Title: Eosinophil granule proteins: form and function.
Volume: 289
Issue: 25
Pages: 17406-15
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Allele
Tg(Epx-EYFP/cre)#Voeh | MGI:6790413
Name: transgene insertion, David Voehringer
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Epx<tm1(icre)Cya> | MGI:7657244
Name: eosinophil peroxidase; targeted mutation 1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:7657664 | C57BL/6J-Epx<tm1(icre)Cya>/Cya
Attribute String: coisogenic, targeted mutation, mutant strain
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Allele
Tg(Epo-DTA)#Nal | MGI:3779020
Name: transgene insertion, Nancy A Lee
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Epx<tm1.1(cre)Jlee> | MGI:5498555
Name: eosinophil peroxidase; targeted mutation 1.1, James J Lee
Allele Type: Targeted
Attribute String: Recombinase
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Strain
MGI:6832813 | B6.Cg-Tg(Epo-DTA)#Nal/JleeJ
Attribute String: congenic, mutant strain, transgenic
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Publication
31415658 | J:278011
First Author: Gorski SA
Year: 2019
Journal: PLoS One
Title: Expression of IL-5 receptor alpha by murine and human lung neutrophils.
Volume: 14
Issue: 8
Pages: e0221113
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Publication
21217761 | J:168251
First Author: Chu VT
Year: 2011
Journal: Nat Immunol
Title: Eosinophils are required for the maintenance of plasma cells in the bone marrow.
Volume: 12
Issue: 2
Pages: 151-9
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Publication
18922934 | J:140660
First Author: Taranova AG
Year: 2008
Journal: Cancer Res
Title: Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung.
Volume: 68
Issue: 20
Pages: 8582-9
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Strain
MGI:6432799 | B6.Cg-Epx<tm1.1(cre)Jlee>/Jlee
Attribute String: mutant strain, targeted mutation, congenic
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Genotype
Genotype
Symbol: Epx/Epx
Background: B6.Cg-Epx/Jlee
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE65753 | Analysis of wildtype and Xbp1-deficient hematopoietic progenitor cell transcriptomes
Series Id: E-GEOD-65753
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
23986549 | J:209545
First Author: Kim JD
Year: 2013
Journal: J Leukoc Biol
Title: An essential role for Rab27a GTPase in eosinophil exocytosis.
Volume: 94
Issue: 6
Pages: 1265-74
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Publication
24379296 | J:209409
First Author: Lilly LM
Year: 2014
Journal: Infect Immun
Title: Eosinophil deficiency compromises lung defense against Aspergillus fumigatus.
Volume: 82
Issue: 3
Pages: 1315-25
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Publication
25504587 | J:223247
First Author: Hashiguchi M
Year: 2015
Journal: Eur J Immunol
Title: IL-33 activates eosinophils of visceral adipose tissue both directly and via innate lymphoid cells.
Volume: 45
Issue: 3
Pages: 876-85
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Publication
20976099 | J:167364
First Author: Babayan SA
Year: 2010
Journal: PLoS Biol
Title: Filarial parasites develop faster and reproduce earlier in response to host immune effectors that determine filarial life expectancy.
Volume: 8
Issue: 10
Pages: e1000525
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Publication
35985335 | J:328550
First Author: Cao YG
Year: 2022
Journal: Cell Host Microbe
Title: Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis.
Volume: 30
Issue: 9
Pages: 1295-1310.e8
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Genotype
Genotype
Symbol: Epx/Epx<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Epx-EYFP/cre)#Voeh/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
12515729 | J:110006
First Author: Gombart AF
Year: 2003
Journal: Blood
Title: Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1.
Volume: 101
Issue: 8
Pages: 3265-73
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Publication
27259856 | J:299331
First Author: Harakal J
Year: 2016
Journal: J Immunol
Title: Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
Volume: 197
Issue: 1
Pages: 27-41
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Publication
18981162 | J:141072
First Author: Ahrens R
Year: 2008
Journal: J Immunol
Title: Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis.
Volume: 181
Issue: 10
Pages: 7390-9
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Publication
24745334 | J:209950
First Author: Chu VT
Year: 2014
Journal: Immunity
Title: Eosinophils promote generation and maintenance of immunoglobulin-A-expressing plasma cells and contribute to gut immune homeostasis.
Volume: 40
Issue: 4
Pages: 582-93
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Publication
21908591 | J:180029
First Author: Weng M
Year: 2011
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension.
Volume: 301
Issue: 6
Pages: L927-36
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Publication
19542471 | J:149965
First Author: Percopo CM
Year: 2009
Journal: J Immunol
Title: Pulmonary eosinophils and their role in immunopathologic responses to formalin-inactivated pneumonia virus of mice.
Volume: 183
Issue: 1
Pages: 604-12
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Publication
19155506 | J:144323
First Author: Fabre V
Year: 2009
Journal: J Immunol
Title: Eosinophil deficiency compromises parasite survival in chronic nematode infection.
Volume: 182
Issue: 3
Pages: 1577-83
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Publication
18316417 | J:133142
First Author: Jacobsen EA
Year: 2008
Journal: J Exp Med
Title: Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells.
Volume: 205
Issue: 3
Pages: 699-710
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Publication
19703974 | J:154126
First Author: Linch SN
Year: 2009
Journal: Infect Immun
Title: Mouse eosinophils possess potent antibacterial properties in vivo.
Volume: 77
Issue: 11
Pages: 4976-82
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Publication
24616476 | J:210233
First Author: Wong TW
Year: 2014
Journal: J Immunol
Title: Eosinophils regulate peripheral B cell numbers in both mice and humans.
Volume: 192
Issue: 8
Pages: 3548-58
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Publication
29327730 | J:278078
First Author: Zhang C
Year: 2018
Journal: Cell Res
Title: Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis.
Volume: 28
Issue: 3
Pages: 323-335
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Publication
15375267 | J:92831
First Author: Lee JJ
Year: 2004
Journal: Science
Title: Defining a link with asthma in mice congenitally deficient in eosinophils.
Volume: 305
Issue: 5691
Pages: 1773-6
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Publication
30185653 | J:267044
 
First Author: Drake MG
Year: 2018
Journal: Sci Transl Med
Title: Eosinophils increase airway sensory nerve density in mice and in human asthma.
Volume: 10
Issue: 457
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Genotype
Genotype
Symbol: Epx/Epx<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
22048766 | J:179701
First Author: Jacobsen EA
Year: 2011
Journal: J Immunol
Title: Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation.
Volume: 187
Issue: 11
Pages: 6059-68
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Publication
25862560 | J:224642
First Author: Schwartz C
Year: 2015
Journal: Blood
Title: Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB-induced Bcl-xL for inhibition of apoptosis.
Volume: 125
Issue: 25
Pages: 3896-904
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Publication
29645346 | J:265358
First Author: Bolden JE
Year: 2018
Journal: J Leukoc Biol
Title: Identification of a Siglec-F+ granulocyte-macrophage progenitor.
Volume: 104
Issue: 1
Pages: 123-133
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Protein
P49290
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
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Protein
Q3V1J3
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: false
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Publication
20038636 | J:159534
First Author: Blanchet MR
Year: 2010
Journal: J Immunol
Title: Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability.
Volume: 184
Issue: 3
Pages: 1292-9
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Publication
23752044 | J:202870
First Author: Ando T
Year: 2013
Journal: J Invest Dermatol
Title: Mast cells are required for full expression of allergen/SEB-induced skin inflammation.
Volume: 133
Issue: 12
Pages: 2695-2705
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Publication
19734227 | J:152787
First Author: McKee AS
Year: 2009
Journal: J Immunol
Title: Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.
Volume: 183
Issue: 7
Pages: 4403-14
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Publication
20876456 | J:167390
First Author: Munks MW
Year: 2010
Journal: Blood
Title: Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo.
Volume: 116
Issue: 24
Pages: 5191-9
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Publication
34099918 | J:308669
First Author: Jacquelot N
Year: 2021
Journal: Nat Immunol
Title: Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.
Volume: 22
Issue: 7
Pages: 851-864
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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