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Search results 201 to 258 out of 258 for Ercc1

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Type Details Score
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26074087 | J:225745
First Author: Manandhar M
Year: 2015
Journal: Gene
Title: The ERCC1 and ERCC4 (XPF) genes and gene products.
Volume: 569
Issue: 2
Pages: 153-61
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HT Sample
Ercc1 KnockOut - Rep 1
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 15
Stage: 28
Structure . Name: pancreas
Curation Status: Curated
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HT Sample
Ercc1 KnockOut - Rep 2
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 15
Stage: 28
Structure . Name: pancreas
Curation Status: Curated
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HT Sample
Ercc1 KnockOut - Rep 3
 
Organism Name: mouse, laboratory
Sex: Male
Age: postnatal day 15
Stage: 28
Structure . Name: pancreas
Curation Status: Curated
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HT Experiment
E-MEXP-1503 | Transcription profiling by array of liver from mice mutant for Ercc1
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-MEXP-834 | Transcription profiling by array of liver from Ercc1 knock-out mice
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
17720715 | -
First Author: Tripsianes K
Year: 2007
Journal: Nucleic Acids Res
Title: Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization.
Volume: 35
Issue: 17
Pages: 5789-98
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DO Term
DOID:0080914 | cerebrooculofacioskeletal syndrome 4
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Allele
Tg(Ttr-Ercc1)17Dwm | MGI:3617449
Name: transgene insertion 17, David W Melton
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Protein Coding Gene
MGI:1917583 | Polr1g
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
GSE219203 | Hypoxia extends lifespan and neurological function in a mouse model of aging
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Ercc1<tm2Dwm> | MGI:3692923
Name: excision repair cross-complementing rodent repair deficiency, complementation group 1; targeted mutation 2, David W Melton
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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HT Experiment
E-MTAB-10393 | Gene expression profiling of Ercc1-/- and age-matched wt pancreata
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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GO Term
GO:0000110 | nucleotide-excision repair factor 1 complex
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GO Term
GO:0070522 | ERCC4-ERCC1 complex
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HT Experiment
E-GEOD-31199 | Down-regulation of cholesterol biosynthesis in forebrains of ERCC1-deficient mice
Series Id: GSE31199
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Ercc1/Ercc1 Tg(Ttr-Ercc1)17Dwm/?
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ercc1/Ercc1 Hr
/Hr
Tg(KRT5-cre)5132Jlj/?
Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J * MF1
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
GSE75000 | Inefficient DNA repair is an aging-related modifier of Parkinson disease
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
16428464 | -
First Author: Guzder SN
Year: 2006
Journal: Mol Cell Biol
Title: Complex formation with damage recognition protein Rad14 is essential for Saccharomyces cerevisiae Rad1-Rad10 nuclease to perform its function in nucleotide excision repair in vivo.
Volume: 26
Issue: 3
Pages: 1135-41
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Protein Domain
IPR004579 | ERCC1/RAD10/SWI10
Type: Family
Description: This family includes Rad10 from budding yeasts, Swi10 from fission yeasts and ERCC-1 from animals andplants. All proteins in this family for which functions are known are components in a multiprotein endonuclease complex (usually made up of Rad1 and Rad10 homologues). This complex is used primarily for nucleotide excision repair but also for some aspects of recombination repair. In budding yeast, Rad10 works as a heterodimer with Rad1, and is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts or cross-linking agents. The complex forms an endonuclease which specifically degrades single-stranded DNA [].ERCC1 and XPF (xeroderma pigmentosum group F-complementing protein) are two structure-specific endonucleases of a class of seven containing an ERCC4 domain. Together they form an obligate complex that functions primarily in nucleotide excision repair (NER), a versatile pathway able to detect and remove a variety of DNA lesions induced by UV light and environmental carcinogens, and secondarily in DNA inter-strand cross-link repair and telomere maintenance. This domain in fact binds simultaneously to both XPF and single-stranded DNA; this ternary complex explains the important role of Ercc1 in targeting its catalytic XPF partner to the NER pre-incision complex [].
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Publication
22209984 | J:182711
First Author: van Dyk E
Year: 2012
Journal: Gene
Title: Impaired DNA repair and genomic stability in hereditary tyrosinemia type 1.
Volume: 495
Issue: 1
Pages: 56-61
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Publication
1639379 | J:78056
First Author: Jansen G
Year: 1992
Journal: Genomics
Title: Physical and genetic characterization of the distal segment of the myotonic dystrophy area on 19q.
Volume: 13
Issue: 3
Pages: 509-17
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Publication
8812448 | J:35442
First Author: Zimmer M
Year: 1996
Journal: Genomics
Title: Cloning of the VASP (vasodilator-stimulated phosphoprotein) genes in human and mouse: structure, sequence, and chromosomal localization.
Volume: 36
Issue: 2
Pages: 227-33
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Publication
10644440 | J:60251
First Author: Shannon M
Year: 1999
Journal: Genomics
Title: Characterization of the mouse Xpf DNA repair gene and differential expression during spermatogenesis.
Volume: 62
Issue: 3
Pages: 427-35
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Publication
16769089 | J:118078
First Author: Wijnhoven SW
Year: 2007
Journal: Mutat Res
Title: Tissue specific mutagenic and carcinogenic responses in NER defective mouse models.
Volume: 614
Issue: 1-2
Pages: 77-94
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Publication
11095693 | J:66149
First Author: Zhang N
Year: 2000
Journal: Nucleic Acids Res
Title: Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts.
Volume: 28
Issue: 23
Pages: 4800-4
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Publication
18584027 | J:161655
First Author: Bennardo N
Year: 2008
Journal: PLoS Genet
Title: Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.
Volume: 4
Issue: 6
Pages: e1000110
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Publication
19109974 | J:168932
First Author: Damrot J
Year: 2009
Journal: J Mol Biol
Title: DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).
Volume: 385
Issue: 5
Pages: 1409-21
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Publication
29447131 | J:262881
First Author: Touat M
Year: 2018
Journal: J Clin Invest
Title: DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.
Volume: 128
Issue: 4
Pages: 1671-1687
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Protein Coding Gene
MGI:1354163 | Ercc4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
H3BLF5
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
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Protein
E9PUM0
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
P07903
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Protein Coding Gene
MGI:106299 | Slx4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99135 | Xpa
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99137 | Xrcc1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1333799 | Xrcc4
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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