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Search results 201 to 223 out of 223 for Fads2

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0.018s
Type Details Score
Publication
First Author: Jojima K
Year: 2020
Journal: FASEB J
Title: Biosynthesis of the anti-lipid-microdomain sphingoid base 4,14-sphingadiene by the ceramide desaturase FADS3.
Volume: 34
Issue: 2
Pages: 3318-3335
Protein Domain
Type: Family
Description: This entry includes fatty acid desaturase family members from bacteria, fungi, plants and animals. Proteins in this family contain the fatty acid desaturase domain (). The eukaryotic members, including human FADS1 and FADS2, are fusion proteins containing an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion [].Three human fatty acid desaturase genes have been identified, fatty acid desaturase 1-3 (FADS1-3) []. FADS1 and FADS2 encode delta-5 desaturase (D5D) and delta-6 desaturase (D6D) respectively. They are membrane-bound enzymes that catalyse the rate-limiting formation of endogenous long-chain polyunsaturated fatty acid (PUFA). FADS3 is a ceramide desaturase that produces sphinga-4,14-dienine-containing ceramides (SPD ceramides). FADS3 also acts as a methyl-end fatty acyl coenzyme A (CoA) desaturase that introduces a cis double bond between the preexisting double bond and the terminal methyl group of the fatty acyl chain. [].
Publication
First Author: Casado ME
Year: 2013
Journal: Prostaglandins Leukot Essent Fatty Acids
Title: Hormone-sensitive lipase deficiency disturbs the fatty acid composition of mouse testis.
Volume: 88
Issue: 3
Pages: 227-33
Publication  
First Author: Zhang JY
Year: 2017
Journal: Prostaglandins Leukot Essent Fatty Acids
Title: Fads3 modulates docosahexaenoic acid in liver and brain.
Volume: 123
Pages: 25-32
Publication
First Author: Leduc MS
Year: 2011
Journal: J Lipid Res
Title: The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol.
Volume: 52
Issue: 6
Pages: 1139-49
Publication  
First Author: Powell DR
Year: 2016
Journal: Diabetes Metab Syndr Obes
Title: Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque.
Volume: 9
Pages: 185-99
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 444  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 383  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false