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Search results 201 to 263 out of 263 for Faf1

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Type Details Score
Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
28443643 | J:250602
 
First Author: Xie F
Year: 2017
Journal: Nat Commun
Title: FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.
Volume: 8
Pages: 15021
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Allele
Faf1<em1Smoc> | MGI:7289582
Name: Fas-associated factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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GXD Expression
GXD Expression
 
Probe: MGI:6403415
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6403443
Age: embryonic day 2.0
Note: Coexprssed with Faf1 in both the cytoplasm and nucleus.
Specimen Label: 4-cell
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6403415
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6403443
Age: embryonic day 2.5
Note: Coexprssed with Faf1 in both the cytoplasm and nucleus.
Specimen Label: 8-Cell
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6403415
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6403443
Age: embryonic day 3.5
Note: Coexprssed with Faf1 in both the cytoplasm and nucleus.
Specimen Label: Blastocyst
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6403415
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6403443
Age: embryonic day 3.0
Note: Coexprssed with Faf1 in both the cytoplasm and nucleus.
Specimen Label: Morula
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6403415
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-09
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6403443
Age: postnatal week 8-10
Note: Coexprssed with Faf1 in both the cytoplasm and nucleus.
Specimen Label: Oocyte
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6403415
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-09
Strength: Present
Sex: Female
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6403443
Age: embryonic day 1.0
Note: Coexprssed with Faf1 in both the cytoplasm and nucleus.
Specimen Label: 2-Cell
Detected: true
Specimen Num: 2
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Interaction Experiment
Baron Y (2014)
Description: VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.
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Interaction Experiment
Yu C (2016)
Description: FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.
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Strain
MGI:6428619 | C57BL/6JSmoc-Faf1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
24885147 | -
 
First Author: Baron Y
Year: 2014
Journal: BMC Biol
Title: VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.
Volume: 12
Pages: 39
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Publication
27662363 | -
First Author: Yu C
Year: 2016
Journal: Cell Death Differ
Title: FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.
Volume: 23
Issue: 11
Pages: 1873-1885
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Publication
24990943 | -
First Author: Zheng S
Year: 2014
Journal: J Biol Chem
Title: Interaction between ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast.
Volume: 289
Issue: 33
Pages: 22692-703
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Protein Domain
IPR006577 | UAS
Type: Domain
Description: UAS is a domain of unknown function found in FAF1 proteins (FAS-associated factor 1) and in otherproteins, many of which are described as having no known function.
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Publication
19722279 | -
First Author: Song J
Year: 2009
Journal: Protein Sci
Title: Structure and interaction of ubiquitin-associated domain of human Fas-associated factor 1.
Volume: 18
Issue: 11
Pages: 2265-76
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Publication
23293021 | -
First Author: Lee JJ
Year: 2013
Journal: J Biol Chem
Title: Complex of Fas-associated factor 1 (FAF1) with valosin-containing protein (VCP)-Npl4-Ufd1 and polyubiquitinated proteins promotes endoplasmic reticulum-associated degradation (ERAD).
Volume: 288
Issue: 10
Pages: 6998-7011
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Publication
22876279 | -
First Author: Lee JJ
Year: 2012
Journal: PLoS One
Title: Ubiquitin-associated (UBA) domain in human Fas associated factor 1 inhibits tumor formation by promoting Hsp70 degradation.
Volume: 7
Issue: 8
Pages: e40361
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Publication
15743842 | -
First Author: Song EJ
Year: 2005
Journal: Mol Cell Biol
Title: Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway.
Volume: 25
Issue: 6
Pages: 2511-24
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Publication
19597341 | -
First Author: Menges CW
Year: 2009
Journal: Cell Cycle
Title: FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.
Volume: 8
Issue: 16
Pages: 2528-34
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Protein Domain
IPR033043 | FAF1-like_UBX
Type: Domain
Description: FAS-associated factor 1 (FAF1) is a multidomain protein involved in various biological processes, including regulation of apoptosis and NFkappaB activity, and ubiquitination and proteasomal degradation []. It has been linked to cancer, asbestos-induced mesotheliomas, and Parkinson's disease []. FAF1 contains multiple ubiquitin-related domains, including ubiquitin-associated (UBA), ubiquitin-like 1 and 2 (UBL1, UBL2), and ubiquitin regulatory X (UBX) domains. FAF1 interacts with polyubiquitinated proteins via its N-terminal UBA domain and with valosin containing protein (VCP) via its C-terminal UBX domain [, , ].This entry represents the UBX domain as found in FAF1 and homologues. The UBX domain has a β-grasp fold similar to that of ubiquitin; however, UBX lacks the C-terminal double glycine motif and is thus unlikely to be conjugated to other proteins.
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Protein Domain
IPR044541 | FAF1_UBA
Type: Domain
Description: FAS-associated factor 1 (FAF1) is a multidomain protein involved in various biologicalprocesses, including regulation of apoptosis and NFkappaB activity, and ubiquitination and proteasomal degradation []. It has been linked to cancer, asbestos-induced mesotheliomas, and Parkinson's disease []. FAF1 contains multiple ubiquitin-related domains, including ubiquitin-associated (UBA), ubiquitin-like 1 and 2 (UBL1, UBL2), and ubiquitin regulatory X (UBX) domains. FAF1 interacts with polyubiquitinated proteins via its N-terminal UBA domain and with valosin containing protein (VCP) via its C-terminal UBX domain [, , ].This entry represents the UBA-like domain found in FAF1.
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Protein
P54731
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: false
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Publication
26811330 | J:236198
First Author: Song S
Year: 2016
Journal: Mol Cell Biol
Title: Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus.
Volume: 36
Issue: 7
Pages: 1136-51
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Protein
D3Z2H4
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: true
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Publication
19223589 | J:146605
First Author: Altomare DA
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice.
Volume: 106
Issue: 9
Pages: 3420-5
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Publication
28717217 | J:258365
First Author: Ogura H
Year: 2017
Journal: Sci Rep
Title: TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
Volume: 7
Issue: 1
Pages: 5519
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Protein
Q3TDN2
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
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Protein
Q6P5G6
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
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Protein
Q3UGV7
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
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Protein
G5E8R8
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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