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Search results 201 to 221 out of 221 for Fastkd2

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Type Details Score
DO Term
DOID:0070424 | combined oxidative phosphorylation deficiency 44
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Publication
25704814 | J:224176
First Author: Jourdain AA
Year: 2015
Journal: Cell Rep
Title: A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.
Volume: 10
Issue: 7
Pages: 1110-21
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Protein
A0A1Y7VJ24
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
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Protein
Q6ZQ14
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: true
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Protein Domain
IPR010622 | FAST_Leu-rich
Type: Domain
Description: This entry represents a conserved region of eukaryotic Fas-activated serine/threonine (FAST) kinases that contains several conserved leucine residues. This domain can be found in the FASTK family members, including FASTK, FASTKD1, FASTKD2 and FASTKD5. FAST kinase has been shown to be rapidly activated during Fas-mediated apoptosis, when it phosphorylates TIA-1, a nuclear RNA-binding protein that has been implicated as an effector of apoptosis []. However, a critical active site residues are not conserved within the family and their kinase activity has been questioned []. FASTK localizes to nucleus, cytosol and mitochondria. FASTKD1, FASTKD2 and FASTKD5 localizes to mitochondria. FASTK has been shown to bind ND6 mRNA and cooperate with the mitochondrial degradosome to ensure regulated ND6 mRNA biogenesis []. FASTKD1, FASTKD2 and FASTKD5 are involved in mitochondrial RNA stability [].
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Protein
Q922E6
Organism: Mus musculus/domesticus
Length: 689  
Fragment?: false
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Protein
F2Z402
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Publication
29036396 | -
First Author: Jourdain AA
Year: 2017
Journal: Nucleic Acids Res
Title: The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Volume: 45
Issue: 19
Pages: 10941-10947
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Protein
Q6DI86
Organism: Mus musculus/domesticus
Length: 829  
Fragment?: false
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Protein
Q8BSN9
Organism: Mus musculus/domesticus
Length: 661  
Fragment?: false
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Protein
Q7TMV3
Organism: Mus musculus/domesticus
Length: 762  
Fragment?: false
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Protein
A0A0R4J291
Organism: Mus musculus/domesticus
Length: 807  
Fragment?: false
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Publication
7544399 | -
First Author: Tian Q
Year: 1995
Journal: J Exp Med
Title: Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis.
Volume: 182
Issue: 3
Pages: 865-74
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Protein
Q9JIX9
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
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Protein
Q91YM4
Organism: Mus musculus/domesticus
Length: 630  
Fragment?: false
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Protein
Q91WQ6
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
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Protein
Q8CAK5
Organism: Mus musculus/domesticus
Length: 545  
Fragment?: false
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Protein
E9QA06
Organism: Mus musculus/domesticus
Length: 408  
Fragment?: false
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Protein
D3Z4M5
Organism: Mus musculus/domesticus
Length: 516  
Fragment?: false
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Protein
Q9CTC9
Organism: Mus musculus/domesticus
Length: 322  
Fragment?: true
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Protein
Q8C725
Organism: Mus musculus/domesticus
Length: 545  
Fragment?: false
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