Type |
Details |
Score |
Publication |
First Author: |
Hellbach N |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. |
Volume: |
23 |
Issue: |
23 |
Pages: |
6177-90 |
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•
•
•
•
•
|
Publication |
First Author: |
Warden CH |
Year: |
1993 |
Journal: |
Genomics |
Title: |
Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. |
Volume: |
18 |
Issue: |
2 |
Pages: |
295-307 |
|
•
•
•
•
•
|
Publication |
First Author: |
MouseBookTM |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Naba A |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. |
Volume: |
7 |
|
Pages: |
40495 |
|
•
•
•
•
•
|
Publication |
First Author: |
Naba A |
Year: |
2012 |
Journal: |
Mol Cell Proteomics |
Title: |
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. |
Volume: |
11 |
Issue: |
4 |
Pages: |
M111.014647 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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|
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•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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•
•
•
•
•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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|
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
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|
|
•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
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•
•
•
•
•
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Publication |
First Author: |
Asselta R |
Year: |
2015 |
Journal: |
Thromb Haemost |
Title: |
Clinical and molecular characterisation of 21 patients affected by quantitative fibrinogen deficiency. |
Volume: |
113 |
Issue: |
3 |
Pages: |
567-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benson MD |
Year: |
1993 |
Journal: |
Nat Genet |
Title: |
Hereditary renal amyloidosis associated with a mutant fibrinogen alpha-chain. |
Volume: |
3 |
Issue: |
3 |
Pages: |
252-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koopman J |
Year: |
1993 |
Journal: |
J Clin Invest |
Title: |
Molecular basis for fibrinogen Dusart (A alpha 554 Arg-->Cys) and its association with abnormal fibrin polymerization and thrombophilia. |
Volume: |
91 |
Issue: |
4 |
Pages: |
1637-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nossel HL |
Year: |
1974 |
Journal: |
J Clin Invest |
Title: |
Measurement of fibrinopeptide A in human blood. |
Volume: |
54 |
Issue: |
1 |
Pages: |
43-53 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Fibrinogens are cleaved by thrombin to yield fibrins, which polymerize to form the insoluble fibrin clot which blocks sites of vascular injury, preventing further blood loss. The clot is subsequently degraded by plasmin (fibrinolysis) []. There are three fibrinogens, alpha, beta and gamma []. Thrombin activates fibrinogen to release a fibrinopeptide []. The newly exposed N terminus forms an Glu-Lys isopeptide bond, which is stabilized by factor XIIIA []. Fibrinogen is also required for successful pregnancy, and in knockout mice fatal uterine bleeding occurs around the tenth day of gestation [].This entry represents the alpha chain of fibrinogen (FGA). Cleavage by thrombin results in the release of fibrinopeptide A []. Several diseases are a result of mutations in the FGA gene, including congenital afibrinogenemia, resulting in a hemophilia which can be mild to severe []; amyloidosis 8, which causes extensive visceral amyloid deposits, renal amyloidosis and hypertension []; and congential dysfibrinogenemia []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
341
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Lebedeva IV |
Year: |
1979 |
Journal: |
Zdravookhr Ross Fed |
Title: |
[Economic effectiveness of dispensary care in textile enterprises]. |
|
Issue: |
4 |
Pages: |
14-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lord ST |
Year: |
1990 |
Journal: |
J Biol Chem |
Title: |
Analysis of fibrinogen A alpha-fusion proteins. Mutants which inhibit thrombin equivalently are not equally good substrates. |
Volume: |
265 |
Issue: |
2 |
Pages: |
838-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kirschbaum NE |
Year: |
1990 |
Journal: |
J Biol Chem |
Title: |
A unique proteolytic fragment of human fibrinogen containing the A alpha COOH-terminal domain of the native molecule. |
Volume: |
265 |
Issue: |
23 |
Pages: |
13669-76 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
789
 |
Fragment?: |
false |
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•
•
•
•
|