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Search results 201 to 300 out of 461 for Flii

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Type Details Score
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Allele
Tg(FLII)1Hdc | MGI:3796829
Name: transgene insertion 1, Hugh D Campbell
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Gene
477419 | LRRFIP1
Type: gene
Organism: dog, domestic
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Gene
485582 | LRRFIP2
Type: gene
Organism: dog, domestic
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Gene
460050 | LRRFIP1
Type: gene
Organism: chimpanzee
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Gene
470788 | LRRFIP2
Type: gene
Organism: chimpanzee
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Gene
301035 | Lrrfip2
Type: gene
Organism: rat
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Gene
367314 | Lrrfip1
Type: gene
Organism: rat
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Gene
510368 | LRRFIP2
Type: gene
Organism: cattle
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Gene
616994 | LRRFIP1
Type: gene
Organism: cattle
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Gene
420759 | LRRFIP2
Type: gene
Organism: chicken
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Gene
428996 | LRRFIP1
Type: gene
Organism: chicken
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Gene
698661 | LRRFIP2
Type: gene
Organism: macaque, rhesus
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Gene
704379 | LRRFIP1
Type: gene
Organism: macaque, rhesus
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Gene
108701678 | flii.L
Type: gene
Organism: frog, African clawed
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Gene
444748 | flii.S
Type: gene
Organism: frog, African clawed
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Publication
9286988 | -
First Author: Stephens C
Year: 1997
Journal: J Bacteriol
Title: Identification of the fliI and fliJ components of the Caulobacter flagellar type III protein secretion system.
Volume: 179
Issue: 17
Pages: 5355-65
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Publication
12180917 | -
First Author: González-Pedrajo B
Year: 2002
Journal: Mol Microbiol
Title: Molecular dissection of Salmonella FliH, a regulator of the ATPase FliI and the type III flagellar protein export pathway.
Volume: 45
Issue: 4
Pages: 967-82
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Publication
10998179 | -
First Author: Minamino T
Year: 2000
Journal: Mol Microbiol
Title: FliH, a soluble component of the type III flagellar export apparatus of Salmonella, forms a complex with FliI and inhibits its ATPase activity.
Volume: 37
Issue: 6
Pages: 1494-503
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Publication
12813095 | -
First Author: Minamino T
Year: 2003
Journal: J Bacteriol
Title: The ATPase FliI can interact with the type III flagellar protein export apparatus in the absence of its regulator, FliH.
Volume: 185
Issue: 13
Pages: 3983-8
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Transgene
MGI:3796828 | Tg(FLII)1Hdc
Type: transgene
Organism: mouse, laboratory
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Publication
1646201 | -
First Author: Vogler AP
Year: 1991
Journal: J Bacteriol
Title: Salmonella typhimurium mutants defective in flagellar filament regrowth and sequence similarity of FliI to F0F1, vacuolar, and archaebacterial ATPase subunits.
Volume: 173
Issue: 11
Pages: 3564-72
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Allele
Gt(ROSA)26Sor<tm1(FLII)Hdc> | MGI:4939369
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hugh D Campbell
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change
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Publication
8943245 | -
First Author: Fan F
Year: 1996
Journal: J Biol Chem
Title: Enzymatic characterization of FliI. An ATPase involved in flagellar assembly in Salmonella typhimurium.
Volume: 271
Issue: 50
Pages: 31981-8
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Publication
19889085 | -
First Author: Minamino T
Year: 2009
Journal: Mol Microbiol
Title: Roles of the extreme N-terminal region of FliH for efficient localization of the FliH-FliI complex to the bacterial flagellar type III export apparatus.
Volume: 74
Issue: 6
Pages: 1471-83
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Publication
9231413 | -
First Author: Jenks PJ
Year: 1997
Journal: FEMS Microbiol Lett
Title: A flagellar-specific ATPase (FliI) is necessary for flagellar export in Helicobacter pylori.
Volume: 152
Issue: 2
Pages: 205-11
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Protein Domain
IPR022426 | FliI_clade3
Type: Family
Description: This family represent the bacterial flagellum-specific ATP synthase, FliI, which is needed for flagellar assembly. FliI is part of the flagellar type III protein export apparatus acting as an ATPase to drive protein export for flagellar biosynthesis [, , ]. When FliI is not engaged in flagellar protein export, FliH, another flagellar type III protein export apparatus protein, functions as a negative regulator to prevent FliI from hydrolysing ATP []. It has been suggested that the N terminus of FliI interacts with FliH, while the the C-terminal domain of FliI possesses the ATPase catalytic function [, ]. The structure of the N-terminally truncated variant of FliI lacking the first 18 residues have been determinded [].This entry represents one (of three) segment of the FliI family tree.
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Ontology Term
- | Bacterial flagellum protein export
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Publication
1828465 | -
First Author: Albertini AM
Year: 1991
Journal: J Bacteriol
Title: The flaA locus of Bacillus subtilis is part of a large operon coding for flagellar structures, motility functions, and an ATPase-like polypeptide.
Volume: 173
Issue: 11
Pages: 3573-9
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Protein Domain
IPR022425 | FliI_clade2
Type: Family
Description: Members of this protein family are the FliI protein of bacterial flagellum systems. FliI is an ATPase that acts to drive protein export for flagellar biosynthesis []. The most closely related family is the YscN family of bacterial type III secretion systems. This entry represents one (of three) segment of the FliI family tree. These have been modeled separately in order to exclude the type III secretion ATPases more effectively.
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Allele
Tg(FLII)2Hdc | MGI:4939366
Name: transgene insertion 2, Hugh D Campbell
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
17012787 | -
First Author: Minamino T
Year: 2006
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun
Title: Crystallization and preliminary X-ray analysis of Salmonella FliI, the ATPase component of the type III flagellar protein-export apparatus.
Volume: 62
Issue: Pt 10
Pages: 973-5
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Protein Domain
IPR020005 | FliI_clade1
Type: Family
Description: Members of this protein family are the FliI protein of bacterial flagellum systems. This protein acts to drive protein export for flagellar biosynthesis []. The most closely related family is the YscN family of bacterial type III secretion systems. This model represents one (of three) segment of the FliI family tree. These have been modeled separately in order to exclude the type III secretion ATPases more effectively.
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Strain
MGI:4941895 | BALB/c-Tg(FLII)1Hdc/AnuApb
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:4941899 | BALB/c-Tg(FLII)2Hdc/AnuApb
Attribute String: transgenic, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Tg(FLII)1Hdc/?
Background: involves: BALB/cJ * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(FLII)1Hdc/Tg(FLII)1Hdc
Background: involves: BALB/cJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(FLII)2Hdc/Tg(FLII)2Hdc
Background: involves: BALB/c
Zygosity: hm
Has Mutant Allele: true
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Publication
9525888 | J:46846
First Author: Liu YT
Year: 1998
Journal: J Biol Chem
Title: Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies.
Volume: 273
Issue: 14
Pages: 7920-7
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Strain
MGI:4941897 | BALB/c-Flii<tm1Hdc> Tg(FLII)1Hdc/AnuApb
Attribute String: coisogenic, mutant strain, targeted mutation, transgenic
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Strain
MGI:4941900 | BALB/c-Flii<tm1Hdc> Tg(FLII)2Hdc/AnuApb
Attribute String: coisogenic, mutant strain, targeted mutation, transgenic
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Publication
15170399 | -
First Author: Minamino T
Year: 2004
Journal: J Mol Microbiol Biotechnol
Title: Self-assembly and type III protein export of the bacterial flagellum.
Volume: 7
Issue: 1-2
Pages: 5-17
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Publication
21611119 | -
First Author: Swietnicki W
Year: 2011
Journal: PLoS One
Title: Identification of small-molecule inhibitors of Yersinia pestis Type III secretion system YscN ATPase.
Volume: 6
Issue: 5
Pages: e19716
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Protein Domain
IPR018006 | Flag_FliJ_proteobac
Type: Family
Description: Many flagellar proteins are exported by a flagellum-specific export pathway. Attempts have been made to characterise the apparatus responsible for this process, by designing assays to screen for mutants with export defects []. Experiments involving filament removal from temperature-sensitive flagellar mutants of Salmonella typhimurium have shown that, while most mutants were able to regrow filaments, flhA, fliH, fliI and fliN mutants showed no or greatly reduced regrowth. This suggests that the corresponding gene products are involved in the process of flagellum-specific export. The sequences of fliH, fliI and the adjacent gene, fliJ, have been deduced. FliJ was shown to encode a protein of molecular mass 17,302 Da []. It is a membrane-associated protein that affects chemotactic events, mutations in FliJ result in failure to respond to chemotactic stimuli.This subgroup is dominated by FliJ proteins found in Proteobacteria.
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Protein Domain
IPR005714 | ATPase_T3SS_FliI/YscN
Type: Family
Description: Proteins in this entry show extensive homology to the ATP synthase F1 beta subunit, and are involved in type III protein secretion. They fall into the two separate functional groups outlined below.The first group, exemplified by the Salmonella typhimurium FliI protein (), is needed for flagellar assembly. Most structural components of the bacterial flagellum are translocated through the central channel of the growing flagellar structure by the type III flagellar protein-export apparatus in an ATPase-driven manner, to be assembled at the growing end. FliI is the ATPase that couples ATP hydrolysis to the translocation reaction [, ].The second group couples ATP hydrolysis to protein translocation in non-flagellar type III secretion systems. Often these systems are involved in virulence and pathogenicity. YscN () from pathogenic Yersinia species, for example, energises the injection of anti host factors directly into eukaryotic cells, thus overcoming host defences [, ].
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Protein
Q3UZ39
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
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Protein
Q91WK0
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
G5E8E1
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
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Protein
Q8C062
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: true
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Protein
A0A087WNU6
Organism: Mus musculus/domesticus
Length: 575  
Fragment?: true
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Protein
Q8BLM1
Organism: Mus musculus/domesticus
Length: 321  
Fragment?: true
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Protein
E9Q9T1
Organism: Mus musculus/domesticus
Length: 628  
Fragment?: false
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Protein
A0A0G2JEF6
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Protein
A0A1L1SQW1
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: false
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Protein
A0A668KLE1
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: false
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Protein
A0A087WPT0
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Protein
A0A0G2JEP4
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Protein
A0A0G2JGZ1
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
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Protein
E9QN52
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
A0A1L1SSC0
Organism: Mus musculus/domesticus
Length: 670  
Fragment?: false
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Protein
A0A087WPK3
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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Protein
A0A0G2JDR6
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
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Protein
A0A1L1SVG1
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
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Protein
Q8BLV4
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: true
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Protein
A0A0R4J169
Organism: Mus musculus/domesticus
Length: 400  
Fragment?: false
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Protein
A0A087WSF5
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: true
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Protein
A0A0G2JFV5
Organism: Mus musculus/domesticus
Length: 437  
Fragment?: false
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Protein
A6H5U5
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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Publication
16199883 | -
First Author: Suriano AR
Year: 2005
Journal: Mol Cell Biol
Title: GCF2/LRRFIP1 represses tumor necrosis factor alpha expression.
Volume: 25
Issue: 20
Pages: 9073-81
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Publication
15677333 | -
First Author: Liu J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis.
Volume: 102
Issue: 6
Pages: 1927-32
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Protein Domain
IPR000563 | Flag_FliH
Type: Family
Description: Many flagellar proteins are exported by a flagellum-specific export pathway. Attempts have been made to characterisethe apparatus responsible for this process, by designing assays to screen for mutants with export defects.Experiments involving filament removal from temperature-sensitive flagellar mutants of Salmonella typhimurium haveshown that, while most mutants were able to regrow filaments, flhA, fliH, fliI and fliN mutants showed no or greatlyreduced regrowth. This suggests that the corresponding gene products are involved in the process of flagellum-specific export []. The sequence of fliH has been deduced and shown to encode a protein of molecular massof 25,782 Da.
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Protein Domain
IPR019139 | LRRFIP1/2
Type: Family
Description: Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA []. It may control smooth muscle cell proliferation following artery injury through PDGFA repression and may also bind double-stranded RNA. It interacts with the leucine-rich repeat domain of human flightless-I (FliI) protein [].Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) may function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin []. It positively regulates Toll-like receptor (TLR) signalling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding [].
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Protein Coding Gene
MGI:1918518 | Lrrfip2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0032754 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1918518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034360 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035259 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035888 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015621 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033902 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7462576
Assay Type: RT-PCR
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3818719
Stage: TS19
Assay Id: MGI:7462621
Age: embryonic day 11.5
Image: S11
Specimen Label: Ect
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7462576
Assay Type: RT-PCR
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736119
Stage: TS19
Assay Id: MGI:7462621
Age: embryonic day 11.5
Image: S11
Specimen Label: Mes
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7462576
Assay Type: RT-PCR
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638517
Stage: TS17
Assay Id: MGI:7462646
Age: embryonic day 10.5
Image: S12
Specimen Label: E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7462576
Assay Type: RT-PCR
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735719
Stage: TS19
Assay Id: MGI:7462646
Age: embryonic day 11.5
Image: S12
Specimen Label: E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7462576
Assay Type: RT-PCR
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1735720
Stage: TS20
Assay Id: MGI:7462646
Age: embryonic day 12.5
Image: S12
Specimen Label: E12.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4416769
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826003
Age: embryonic day 14.5
Image: euxassay_012383_01
Specimen Label: euxassay_012383_01
Detected: true
Specimen Num: 1
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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