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Search results 201 to 300 out of 350 for Fpr2

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Takano T
Year: 1997
Journal: J Exp Med
Title: Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.
Volume: 185
Issue: 9
Pages: 1693-704
Publication
First Author: Stempel H
Year: 2016
Journal: J Biol Chem
Title: Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems.
Volume: 291
Issue: 18
Pages: 9762-75
Publication
First Author: Levy BD
Year: 2002
Journal: Nat Med
Title: Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
Volume: 8
Issue: 9
Pages: 1018-23
Publication
First Author: Coffelt SB
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.
Volume: 106
Issue: 10
Pages: 3806-11
Publication
First Author: Wu J
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Lipoxin A4 inhibits the production of proinflammatory cytokines induced by β-amyloid in vitro and in vivo.
Volume: 408
Issue: 3
Pages: 382-7
GXD Expression  
Probe: MGI:7434679
Assay Type: RNA in situ
Annotation Date: 2023-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3666228
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434721
Age: postnatal day 30
Note: Co-labeling with the recombinase reporter is seen.
Specimen Label: S1F - Fpr-rs4
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7434682
Assay Type: RNA in situ
Annotation Date: 2023-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3666228
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434723
Age: postnatal day 30
Note: Co-labeling with the recombinase reporter is seen.
Specimen Label: S1F - Fpr-rs4
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7434681
Assay Type: RNA in situ
Annotation Date: 2023-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3666228
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434722
Age: postnatal day 30
Note: Co-labeling with the recombinase reporter is seen.
Specimen Label: S1F - Fpr-rs6
Detected: true
Specimen Num: 1
Publication
First Author: Yang D
Year: 2002
Journal: J Leukoc Biol
Title: Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation.
Volume: 72
Issue: 3
Pages: 598-607
Publication
First Author: Migeotte I
Year: 2005
Journal: J Exp Med
Title: Identification and characterization of an endogenous chemotactic ligand specific for FPRL2.
Volume: 201
Issue: 1
Pages: 83-93
Protein Domain
Type: Family
Description: Formyl peptide receptors (FPR) are members of the rhodopsin-like G-protein coupled receptor family and are involved in chemotaxis [, ]. They were originally identified by their ability to bind N-formyl peptides (typified by fMet-Leu-Phe (fMLP)), produced by the degradation of either bacterial or host cells [, ]but subsequent ligands have been discovered, containing many microbial agonists derived from both bacteria and viruses [, ].FPRs were initially found on leukocytes, but they are expressed in other cells, for example, immature dendritic cells, platelets, microglial cells, astrocytes, fibroblasts and platelets [, ]. FPRs are expressed at high levels on polymorphonuclear and mononuclear phagocytes. Formyl peptide receptors are not only involved in mediating immune cell response to infection, but also act to suppress the immune system under certain conditions []. The main responses elicited upon ligation of formylated peptides, are those of morphological polarization, locomotion, production of reactive-oxygen species and release of proteolytic enzymes []. There are three formyl peptide receptor subtypes, FPR1, FPR2 and FPR3 [, ]. The sequence similarity between FPR1 and FPR2 is high (69%), and although there is a large sequence similarity also between FPR2 and FPR3 (83%), FPR3 can not bind formylated peptides [, ]. Formyl peptide receptor 3 (FPR3) is primarily a receptor of monocytes, macrophages and dendritic cells. It is also expressed on mouse, but not human, neutrophils [, , ]. Although FPR3 is found in human monocytes, studies have shown that approximately one third of individuals lack cell surface expression of this receptor [, ]. The functions of FPR3, other than directing cell migration, remain to be characterised [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 7
Note: Expressed in the dendrites and somata of the sensory neurons.
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 49
Note: Expressed in the dendrites and somata of the sensory neurons.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal adult
Note: Expressed in axonal projections that reached the accessory olfactory bulb.
Specimen Label: 3C
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 7
Note: Expressed in axonal projections that reached the accessory olfactory bulb.
Specimen Label: 3D
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 21
Note: Expressed in axonal projections that reached the accessory olfactory bulb.
Specimen Label: 3E
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Female
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal adult
Note: Expressed in axonal projections that reached the accessory olfactory bulb.
Specimen Label: 3F
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Female
Emaps: EMAPS:3510628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal adult
Note: Expressed in axonal projections that reached the accessory olfactory bulb.
Specimen Label: 3G
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3510627
Stage: TS27
Assay Id: MGI:5614661
Age: postnatal day 0
Specimen Label: not shown
Detected: false
Specimen Num: 11
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-09
Strength: Present
Sex: Male
Emaps: EMAPS:3510828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614788
Age: postnatal adult
Note: Mostly expressed in the rostral area (7.2 +/- 1.3 and 7.4 +/- 2.2 glomeruli in the left and right accessory bulbs respectively).
Specimen Label: Male
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-09
Strength: Present
Sex: Female
Emaps: EMAPS:3510828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5614788
Age: postnatal adult
Note: Mostly expressed in the rostral area (7.6 +/- 2.3 and 6.6 +/- 1.1 glomeruli in the left and right accessory bulbs respectively).
Specimen Label: Female
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3510828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614674
Age: postnatal week 7
Note: Similar expression as in C57BL/6.
Specimen Label: S2 BALB/c
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3510828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal day 30
Image: 6K
Note: Expression is seen in the axons.
Specimen Label: 6K
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3510828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal day 30
Image: 6L
Note: Expression is seen in the axons.
Specimen Label: 6L
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3666228
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal week 6
Image: 4A
Specimen Label: 4A
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5614661
Age: embryonic day 16.0
Note: Expressed in the somata of the sensory neurons.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1761222
Stage: TS22
Assay Id: MGI:5614661
Age: embryonic day 14.5
Specimen Label: not shown
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5614661
Age: embryonic day 18.0
Specimen Label: not shown
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5614661
Age: postnatal day 0
Specimen Label: not shown
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 21
Note: The numbers of cells expressing the receptor are 942 +/- 121 and 930 +/- 71 in males and females.
Specimen Label: not shown
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal year 1
Note: No significant variation was observed, compared with P21.
Specimen Label: not shown
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Graded
Stage: TS28
Assay Id: MGI:5614674
Age: postnatal day 7
Note: Expressed in a rostrocaudal gradient.
Specimen Label: 2 - P7
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Graded
Stage: TS28
Assay Id: MGI:5614674
Age: postnatal day 49
Note: The rostrocaudal gradient was strongly reduced.
Specimen Label: 2 - P49
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761227
Pattern: Graded
Stage: TS27
Assay Id: MGI:5614674
Age: postnatal day 0
Note: Expressed in a rostrocaudal gradient.
Specimen Label: 2 - P0
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Graded
Stage: TS28
Assay Id: MGI:5614674
Age: postnatal day 21
Note: Expressed in a rostrocaudal gradient.
Specimen Label: 2 - P21
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614675
Age: postnatal
Note: Expressed in the dendritic endings.
Specimen Label: 3B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614675
Age: postnatal
Note: Expressed in the dendritic endings.
Specimen Label: 3A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 7
Note: The number of cells expressing the receptor drastically increased, which are 587 +/- 64 and 612 +/- 49 in males and females.
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5614631
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1761228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5614661
Age: postnatal day 49
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844428
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal week 6
Image: 3D
Specimen Label: 3D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7434665
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844428
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434705
Age: postnatal week 6
Image: 3D
Specimen Label: 3D
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7434694
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844428
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434707
Age: postnatal day 15-17
Image: 5H
Specimen Label: 5H
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844428
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal day 7
Specimen Label: 5F - 7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844428
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal day 15
Specimen Label: 5F - 15
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7434662
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844428
Pattern: Single cells
Stage: TS28
Assay Id: MGI:7434346
Age: postnatal day 30
Specimen Label: 5F - 30
Detected: true
Specimen Num: 5
Protein
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false