Type |
Details |
Score |
Genotype |
Symbol: |
Cxcr4/Cxcr4 Gab1/Gab1 |
Background: |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gab1/Gab1 Met/Met |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
152
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
591
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd44/Cd44 Gab1/Gab1<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Hopper NA |
Year: |
2006 |
Journal: |
Genetics |
Title: |
The adaptor protein soc-1/Gab1 modifies growth factor receptor output in Caenorhabditis elegans. |
Volume: |
173 |
Issue: |
1 |
Pages: |
163-75 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
248
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
450
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
159
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
177
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1217
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
208
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
162
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Zoratti GL |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. |
Volume: |
6 |
|
Pages: |
6776 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hadari YR |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways. |
Volume: |
98 |
Issue: |
15 |
Pages: |
8578-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JH |
Year: |
2018 |
Journal: |
Mol Cell |
Title: |
EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation. |
Volume: |
70 |
Issue: |
2 |
Pages: |
197-210.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirose M |
Year: |
2018 |
Journal: |
Epigenetics |
Title: |
Aberrant imprinting in mouse trophoblast stem cells established from somatic cell nuclear transfer-derived embryos. |
Volume: |
13 |
Issue: |
7 |
Pages: |
693-703 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1210
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
595
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
665
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
695
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
666
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
556
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
596
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
725
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
666
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
665
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishida K |
Year: |
1999 |
Journal: |
Blood |
Title: |
Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. |
Volume: |
93 |
Issue: |
6 |
Pages: |
1809-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolf I |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
Gab3, a new DOS/Gab family member, facilitates macrophage differentiation. |
Volume: |
22 |
Issue: |
1 |
Pages: |
231-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seiffert M |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent. |
Volume: |
23 |
Issue: |
7 |
Pages: |
2415-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gu H |
Year: |
2001 |
Journal: |
Nature |
Title: |
Essential role for Gab2 in the allergic response. |
Volume: |
412 |
Issue: |
6843 |
Pages: |
186-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cully M |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice. |
Volume: |
101 |
Issue: |
43 |
Pages: |
15358-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saxton TM |
Year: |
2001 |
Journal: |
Curr Biol |
Title: |
Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis. |
Volume: |
11 |
Issue: |
9 |
Pages: |
662-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ryu HH |
Year: |
2019 |
Journal: |
Sci Signal |
Title: |
Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory. |
Volume: |
12 |
Issue: |
571 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Solich J |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
MicroRNA Let-7e in the Mouse Prefrontal Cortex Differentiates Restraint-Stress-Resilient Genotypes from Susceptible Genotype. |
Volume: |
22 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Schneeberger VE |
Year: |
2014 |
Journal: |
Carcinogenesis |
Title: |
SHP2E76K mutant promotes lung tumorigenesis in transgenic mice. |
Volume: |
35 |
Issue: |
8 |
Pages: |
1717-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song X |
Year: |
2015 |
Journal: |
Cancer Res |
Title: |
ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas. |
Volume: |
75 |
Issue: |
6 |
Pages: |
1035-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Agazie YM |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Development of an efficient "substrate-trapping" mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates. |
Volume: |
278 |
Issue: |
16 |
Pages: |
13952-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tao Y |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes. |
Volume: |
147 |
Issue: |
4 |
Pages: |
1685-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang YM |
Year: |
2015 |
Journal: |
J Invest Dermatol |
Title: |
Requirement of Gαi1/3-Gab1 signaling complex for keratinocyte growth factor-induced PI3K-AKT-mTORC1 activation. |
Volume: |
135 |
Issue: |
1 |
Pages: |
181-191 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu T |
Year: |
2019 |
Journal: |
J Neurochem |
Title: |
Macrophage stimulating protein preserves blood brain barrier integrity after intracerebral hemorrhage through recepteur d'origine nantais dependent GAB1/Src/β-catenin pathway activation in a mouse model. |
Volume: |
148 |
Issue: |
1 |
Pages: |
114-126 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
593
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Raghavan S |
Year: |
2018 |
Journal: |
Circulation |
Title: |
Protein Kinase Cθ Via Activating Transcription Factor 2-Mediated CD36 Expression and Foam Cell Formation of Ly6Chi Cells Contributes to Atherosclerosis. |
Volume: |
138 |
Issue: |
21 |
Pages: |
2395-2412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goel HL |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
beta1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts. |
Volume: |
65 |
Issue: |
15 |
Pages: |
6692-700 |
|
•
•
•
•
•
|
Publication |
First Author: |
Musilova K |
Year: |
2015 |
Journal: |
Leukemia |
Title: |
MicroRNAs in B-cell lymphomas: how a complex biology gets more complex. |
Volume: |
29 |
Issue: |
5 |
Pages: |
1004-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Landry M |
Year: |
2016 |
Journal: |
Biochem J |
Title: |
Non-canonical dynamic mechanisms of interaction between the p66Shc protein and Met receptor. |
Volume: |
473 |
Issue: |
11 |
Pages: |
1617-27 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
724
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
535
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1068
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
|
|
|
•
•
•
•
•
|