Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757722 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421292 |
Age: |
embryonic day 14.5 |
Image: |
MH832; Specimen C1404 |
|
Specimen Label: |
MH832; Specimen C1404 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421292 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH832; Specimen C1404 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421292 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH832; Specimen C1404 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1802422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421292 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH832; Specimen C1404 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421292 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the skull (base and vault). |
Specimen Label: |
MH832; Specimen C1404 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:2823626 |
|
Stage: |
TS26 |
Assay Id: |
MGI:5540442 |
Age: |
embryonic day 17.5 |
Image: |
GUDMAP:15687 |
|
Specimen Label: |
GUDMAP:15687 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724632 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421292 |
Age: |
embryonic day 14.5 |
Image: |
MH832; Specimen C1404 |
Note: |
Expression was weak in whisker follicle. |
Specimen Label: |
MH832; Specimen C1404 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
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Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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HT Experiment |
Series Id: |
GSE48911 |
Experiment Type: |
transcription profiling by array |
Study Type: |
Baseline |
Source: |
ArrayExpress |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1009
 |
Fragment?: |
false |
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•
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Publication |
First Author: |
Nakamoto C |
Year: |
2020 |
Journal: |
J Comp Neurol |
Title: |
Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain. |
Volume: |
528 |
Issue: |
6 |
Pages: |
1003-1027 |
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•
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Publication |
First Author: |
Bao X |
Year: |
2009 |
Journal: |
J Neurosci |
Title: |
Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. |
Volume: |
29 |
Issue: |
44 |
Pages: |
13929-44 |
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•
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Allele |
Name: |
glutamate dehydrogenase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Interaction Experiment |
Description: |
Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain. |
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Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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DO Term |
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Publication |
First Author: |
Suryavanshi PS |
Year: |
2016 |
Journal: |
Mol Pharmacol |
Title: |
Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus. |
Volume: |
90 |
Issue: |
2 |
Pages: |
96-105 |
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•
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•
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Publication |
First Author: |
Lomeli H |
Year: |
1993 |
Journal: |
FEBS Lett |
Title: |
The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family. |
Volume: |
315 |
Issue: |
3 |
Pages: |
318-22 |
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•
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Protein Domain |
Type: |
Family |
Description: |
Glutamate delta-1 (GluD1) and delta-2 (GluD2) constitute the delta subfamily of ionotropic glutamate receptors. They have a crucial role in synapse formation by interacting with presynaptic proteins such as Neurexin-1. GluD1 is expressed diffusively throughout the forebrain and cerebellum during early development and adulthood, with high levels in the hippocampus [, ], whereas GluD2 is predominantly expressed in the Purkinje cells of the cerebellum [].It has been shown that delta receptors (GluD1, GluD2) might play a role in the underlying pathophysiology of autism and schizophrenia [].This entry represents the ionotropic glutamate receptors delta 1 and delta 2. |
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Publication |
First Author: |
Zhou W |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
SENP1-Sirt3 signaling promotes α-ketoglutarate production during M2 macrophage polarization. |
Volume: |
39 |
Issue: |
2 |
Pages: |
110660 |
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•
•
•
•
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Publication |
First Author: |
Benamer N |
Year: |
2018 |
Journal: |
Mol Psychiatry |
Title: |
GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons. |
Volume: |
23 |
Issue: |
3 |
Pages: |
691-700 |
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•
•
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•
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Publication |
First Author: |
Matheson LS |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4(+) T cell. |
Volume: |
12 |
Issue: |
1 |
Pages: |
19657 |
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•
•
•
•
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Publication |
First Author: |
Hepp R |
Year: |
2015 |
Journal: |
Brain Struct Funct |
Title: |
Glutamate receptors of the delta family are widely expressed in the adult brain. |
Volume: |
220 |
Issue: |
5 |
Pages: |
2797-815 |
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•
•
•
•
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Publication |
First Author: |
Liu J |
Year: |
2020 |
Journal: |
Neurobiol Dis |
Title: |
Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity. |
Volume: |
137 |
|
Pages: |
104746 |
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•
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•
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Publication |
First Author: |
Yadav R |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. |
Volume: |
7 |
Issue: |
3 |
Pages: |
e32969 |
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•
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Publication |
First Author: |
Gandhi PJ |
Year: |
2021 |
Journal: |
Cells |
Title: |
Dysfunction of Glutamate Delta-1 Receptor-Cerebellin 1 Trans-Synaptic Signaling in the Central Amygdala in Chronic Pain. |
Volume: |
10 |
Issue: |
10 |
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•
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•
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Publication |
First Author: |
Dai J |
Year: |
2022 |
Journal: |
Elife |
Title: |
Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner. |
Volume: |
11 |
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•
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•
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•
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Publication |
First Author: |
Seigneur E |
Year: |
2017 |
Journal: |
J Comp Neurol |
Title: |
Cerebellins are differentially expressed in selective subsets of neurons throughout the brain. |
Volume: |
525 |
Issue: |
15 |
Pages: |
3286-3311 |
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•
•
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•
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Publication |
First Author: |
Seigneur E |
Year: |
2021 |
Journal: |
Mol Psychiatry |
Title: |
Cerebellin-2 regulates a serotonergic dorsal raphe circuit that controls compulsive behaviors. |
Volume: |
26 |
Issue: |
12 |
Pages: |
7509-7521 |
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•
•
•
•
•
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Publication |
First Author: |
Plaitakis A |
Year: |
2019 |
Journal: |
Neurochem Res |
Title: |
Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution. |
Volume: |
44 |
Issue: |
1 |
Pages: |
154-169 |
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