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Search results 201 to 233 out of 233 for Gpat2

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Type Details Score
Protein
Q14DK4
Organism: Mus musculus/domesticus
Length: 801  
Fragment?: false
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Publication
26268560 | -
First Author: Garcia-Fabiani MB
Year: 2015
Journal: Biochem J
Title: Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis.
Volume: 471
Issue: 2
Pages: 211-20
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Protein
Q14DK4-3
Organism: Mus musculus/domesticus
Length: 798  
Fragment?: false
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Protein
Q14DK4-2
Organism: Mus musculus/domesticus
Length: 797  
Fragment?: false
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GXD Expression
GXD Expression
 
Probe: MGI:7619033
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7619098
Age: embryonic day 16.5
Note: The granular staining pattern was retained in the prospermatogonia of the Gpat2 mutant.
Specimen Label: S2A Gpat2delta/delta
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3033763
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7619099
Age: embryonic day 16.5
Note: The granular staining pattern was retained in the prospermatogonia of the Gpat2 mutant.
Specimen Label: S2B Gpat2delta/delta
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5315099
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7619070
Age: postnatal day 2
Note: The number of germ cells was slightly reduced in the Gpat2 mutant mice.
Specimen Label: S5A P2 delta/delta
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
 
Probe: MGI:7619033
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7619098
Age: embryonic day 16.5
Note: Expression was detected in a granular pattern in prospermatogonia. Gpat2 staining was adjacent or co-localized with Piwil2 immunostaining.
Specimen Label: S2A Gpat2+/delta
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3033763
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797524
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7619099
Age: embryonic day 16.5
Note: Expression was detected in a granular pattern in prospermatogonia. Gpat2 staining was adjacent or co-localized with Tdrd1 immunostaining.
Specimen Label: S2B Gpat2+/delta
Detected: true
Specimen Num: 1
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Publication
7897322 | -
First Author: Minskoff SA
Year: 1994
Journal: J Lipid Res
Title: Regulation of phosphatidic acid biosynthetic enzymes in Saccharomyces cerevisiae.
Volume: 35
Issue: 12
Pages: 2254-62
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Publication
18931347 | -
 
First Author: Shindou H
Year: 2009
Journal: J Lipid Res
Title: Recent progress on acyl CoA: lysophospholipid acyltransferase research.
Volume: 50 Suppl
Pages: S46-51
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Protein Domain
IPR041728 | GPAT/DHAPAT_LPLAT
Type: Domain
Description: Proteins containing this domain are lysophospholipid acyltransferases(LPLATs) such as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) []and glycerol 3-phosphate acyltransferases GPAT1 and GPAT2 []. They are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as dihydroxyacetone phosphate or glycerol 3-phosphate respectively [].
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Publication
25948680 | J:246870
First Author: Qiao L
Year: 2015
Journal: Diabetes
Title: Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice.
Volume: 64
Issue: 9
Pages: 3111-20
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Protein
P98192
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q61586
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Protein
A0A494BA32
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Protein
Q545P6
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q69ZG4
Organism: Mus musculus/domesticus
Length: 848  
Fragment?: true
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Protein
Q3TKG9
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q3UBU1
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q8R390
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q05DV2
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: true
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Protein
Q9CT84
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: true
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Publication
16294310 | -
First Author: Gully D
Year: 2006
Journal: Proteomics
Title: A protein network for phospholipid synthesis uncovered by a variant of the tandem affinity purification method in Escherichia coli.
Volume: 6
Issue: 1
Pages: 282-93
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Publication
15687349 | -
First Author: Liu D
Year: 2005
Journal: J Lipid Res
Title: Role of dihydroxyacetonephosphate acyltransferase in the biosynthesis of plasmalogens and nonether glycerolipids.
Volume: 46
Issue: 4
Pages: 727-35
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Publication
9536089 | J:47622
First Author: Ofman R
Year: 1998
Journal: Hum Mol Genet
Title: Acyl-CoA:dihydroxyacetonephosphate acyltransferase: cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2.
Volume: 7
Issue: 5
Pages: 847-53
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Publication
12874108 | J:84690
First Author: Rodemer C
Year: 2003
Journal: Hum Mol Genet
Title: Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice.
Volume: 12
Issue: 15
Pages: 1881-95
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Publication
30813330 | -
 
First Author: Karasawa K
Year: 2019
Journal: Int J Mol Sci
Title: Transcriptional Regulation of Acyl-CoA:Glycerol-sn-3-Phosphate Acyltransferases.
Volume: 20
Issue: 4
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Publication
32817111 | -
 
First Author: Noga MJ
Year: 2020
Journal: mBio
Title: Posttranslational Control of PlsB Is Sufficient To Coordinate Membrane Synthesis with Growth in Escherichia coli.
Volume: 11
Issue: 4
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Protein
A0A494BAR5
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein Domain
IPR022284 | GPAT/DHAPAT
Type: Family
Description: This entry represents the Glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase (GPAT/DAPAT) family. This entry includes PlsB, a GPAT from E. coli in which membrane synthesis depends on allosteric control of this enzyme. PlsB regulation plays an important role in the phospholipid synthesis pathway and is part of the response to certain stress signals []. In many other bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system [, ].GPATs are classified into four isoforms in mammals; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane []. This entry includes the mitochondrial isoform, GPAT1 and GPAT2.Dihydroxyacetonephosphate acyltransferase (DHAPAT) catalyses the first step in the biosynthesis of ether phospholipid plasmalogen, and may play also a significant role in nonether glycerolipid biosynthesis [, ]. In humans, mutations in DHAPAT results in the genetic disorder rhizomelic chondrodysplasia punctata type 2, characterised by rhizomelic shortening of femur and humerus, cataract,and severe mental retardation [].
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Protein Domain
IPR045520 | GPAT/DHAPAT_C
Type: Domain
Description: This entry represents the C-terminal domain of glycerol-3-phosphate acyltransferases (GPATs) and dihydroxyacetone phosphate acyltransferases.Dihydroxyacetonephosphate acyltransferase (DHAPAT) catalyses the first step in the biosynthesis of ether phospholipid plasmalogen, and may play also a significant role in nonether glycerolipid biosynthesis [, ]. In humans, mutations in DHAPAT results in the genetic disorder rhizomelic chondrodysplasia punctata type 2, characterised by rhizomelic shortening of femur and humerus, cataract,and severe mental retardation [].This entry includes PlsB, a GPAT from E. coli in which membrane synthesis depends on allosteric control of this enzyme. PlsB regulation plays an important role in the phospholipid synthesis pathway and is part of the response to certain stress signals []. In many other bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system [, ].GPATs are classified into four isoforms in mammals; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane []. This entry includes the mitochondrial isoform GPAT.
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Publication
16949372 | -
First Author: Lu YJ
Year: 2006
Journal: Mol Cell
Title: Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens.
Volume: 23
Issue: 5
Pages: 765-72
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