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Search results 201 to 300 out of 379 for Gsdmd

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1557781
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825252
Age: embryonic day 14.5
Image: euxassay_003539_21
Specimen Label: euxassay_003539_21
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:1557781
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1625523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825252
Age: embryonic day 14.5
Image: euxassay_003539_22
Specimen Label: euxassay_003539_22
Detected: true
Specimen Num: 14
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Publication
35588457 | J:331823
First Author: Eltobgy MM
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Volume: 119
Issue: 21
Pages: e2202012119
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Publication
38195694 | J:351181
First Author: Ma F
Year: 2024
Journal: Nat Commun
Title: Gasdermin E dictates inflammatory responses by controlling the mode of neutrophil death.
Volume: 15
Issue: 1
Pages: 386
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Publication
35288534 | J:322823
First Author: Tonnus W
Year: 2022
Journal: Cell Death Dis
Title: Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury.
Volume: 13
Issue: 3
Pages: 236
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Publication
32917873 | J:297014
First Author: Volchuk A
Year: 2020
Journal: Nat Commun
Title: Indirect regulation of HMGB1 release by gasdermin D.
Volume: 11
Issue: 1
Pages: 4561
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Publication
29274245 | J:261341
First Author: Heilig R
Year: 2018
Journal: Eur J Immunol
Title: The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice.
Volume: 48
Issue: 4
Pages: 584-592
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Publication
28045099 | J:241308
 
First Author: Rogers C
Year: 2017
Journal: Nat Commun
Title: Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.
Volume: 8
Pages: 14128
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Publication
33372132 | J:299605
 
First Author: Sateriale A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6.
Volume: 118
Issue: 2
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Publication
36229563 | J:354540
First Author: Dvoriantchikova G
Year: 2022
Journal: Sci Rep
Title: Multiple types of programmed necrosis such as necroptosis, pyroptosis, oxytosis/ferroptosis, and parthanatos contribute simultaneously to retinal damage after ischemia-reperfusion.
Volume: 12
Issue: 1
Pages: 17152
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Publication
33640898 | J:338994
First Author: Yuan C
Year: 2021
Journal: Signal Transduct Target Ther
Title: Blocking Msr1 by berberine alkaloids inhibits caspase-11-dependent coagulation in bacterial sepsis.
Volume: 6
Issue: 1
Pages: 92
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Publication
34097907 | J:308772
 
First Author: Carter JJ
Year: 2021
Journal: Exp Eye Res
Title: Atypical cytomegalovirus retinal disease in pyroptosis-deficient mice with murine acquired immunodeficiency syndrome.
Volume: 209
Pages: 108651
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Publication
36640341 | J:332901
First Author: Meyers AK
Year: 2023
Journal: Cell Rep
Title: Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation.
Volume: 42
Issue: 1
Pages: 111941
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Publication
33125053 | J:307787
 
First Author: Zhang L
Year: 2021
Journal: J Exp Med
Title: Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death.
Volume: 218
Issue: 2
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Publication
29281832 | J:268223
First Author: Schneider KS
Year: 2017
Journal: Cell Rep
Title: The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
Volume: 21
Issue: 13
Pages: 3846-3859
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Publication
37798443 | J:341724
First Author: den Hartigh AB
Year: 2023
Journal: Commun Biol
Title: Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis.
Volume: 6
Issue: 1
Pages: 1010
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Publication
36045672 | J:327923
 
First Author: Huot-Marchand S
Year: 2022
Journal: Front Immunol
Title: Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3.
Volume: 13
Pages: 918507
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Publication
34659244 | J:312710
 
First Author: Son S
Year: 2021
Journal: Front Immunol
Title: Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu.
Volume: 12
Pages: 746032
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Publication
37913775 | J:353764
First Author: Reinke S
Year: 2023
Journal: Cell Rep Med
Title: Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms.
Volume: 4
Issue: 11
Pages: 101245
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Publication
36155655 | J:336980
   
First Author: Cohen H
Year: 2022
Journal: Elife
Title: Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors.
Volume: 11
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Publication
31411729 | J:287943
First Author: Chen KW
Year: 2020
Journal: Eur J Immunol
Title: Pannexin-1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation.
Volume: 50
Issue: 2
Pages: 170-177
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Publication
35624490 | J:326726
First Author: Dai S
Year: 2022
Journal: J Neuroinflammation
Title: Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway.
Volume: 19
Issue: 1
Pages: 122
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Publication
37001519 | J:334741
First Author: Zhu F
Year: 2023
Journal: Immunity
Title: The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome.
Volume: 56
Issue: 4
Pages: 753-767.e8
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Publication
35247698 | J:323991
 
First Author: Xiao T
Year: 2022
Journal: Biochem Biophys Res Commun
Title: NLRP3 inflammasome of microglia promotes A1 astrocyte transformation, neo-neuron decline and cognition impairment in endotoxemia.
Volume: 602
Pages: 1-7
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Publication
35235356 | J:334669
First Author: Eislmayr K
Year: 2022
Journal: Sci Adv
Title: Nonredundancy of IL-1α and IL-1β is defined by distinct regulation of tissues orchestrating resistance versus tolerance to infection.
Volume: 8
Issue: 9
Pages: eabj7293
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Publication
33414187 | J:304358
 
First Author: Chuang HC
Year: 2021
Journal: eNeuro
Title: Lytic Cell Death in Specific Microglial Subsets Is Required for Preventing Atypical Behavior in Mice.
Volume: 8
Issue: 1
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Publication
35332327 | J:325397
First Author: Tahtinen S
Year: 2022
Journal: Nat Immunol
Title: IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.
Volume: 23
Issue: 4
Pages: 532-542
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Publication
30718379 | J:285504
 
First Author: de Vasconcelos NM
Year: 2019
Journal: Life Sci Alliance
Title: DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
Volume: 2
Issue: 1
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Publication
28771586 | J:283562
First Author: Mascarenhas DPA
Year: 2017
Journal: PLoS Pathog
Title: Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.
Volume: 13
Issue: 8
Pages: e1006502
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Publication
37998361 | J:342947
 
First Author: Spurlock M
Year: 2023
Journal: Cells
Title: The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes.
Volume: 12
Issue: 22
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Publication
34715018 | J:323769
First Author: Wu J
Year: 2021
Journal: Immunity
Title: APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.
Volume: 54
Issue: 11
Pages: 2632-2649.e6
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Publication
30209191 | J:266201
First Author: Wang Y
Year: 2018
Journal: J Immunol
Title: Cutting Edge: The Heat Shock Protein gp96 Activates Inflammasome-Signaling Platforms in APCs.
Volume: 201
Issue: 8
Pages: 2209-2214
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Publication
37023458 | J:336845
First Author: Bauer DL
Year: 2023
Journal: J Immunol
Title: The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells.
Volume: 210
Issue: 10
Pages: 1519-1530
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Publication
34939932 | J:317681
   
First Author: Deets KA
Year: 2021
Journal: Elife
Title: Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen.
Volume: 10
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Publication
36670138 | J:333385
First Author: Hashimoto S
Year: 2023
Journal: Sci Rep
Title: Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Volume: 13
Issue: 1
Pages: 1109
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Publication
38297162 | J:347275
First Author: Shim DW
Year: 2024
Journal: Exp Mol Med
Title: Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis.
Volume: 56
Issue: 2
Pages: 370-382
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Publication
32164878 | J:290377
First Author: Huang LS
Year: 2020
Journal: Immunity
Title: mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury.
Volume: 52
Issue: 3
Pages: 475-486.e5
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Publication
34260403 | J:332350
 
First Author: Chen KW
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Volume: 118
Issue: 28
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Publication
31076358 | J:282475
First Author: Wu C
Year: 2019
Journal: Immunity
Title: Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.
Volume: 50
Issue: 6
Pages: 1401-1411.e4
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Publication
32555186 | J:305388
First Author: Zhang C
Year: 2020
Journal: Cell Death Dis
Title: Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages.
Volume: 11
Issue: 6
Pages: 470
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Publication
17350798 | J:121808
First Author: Tamura M
Year: 2007
Journal: Genomics
Title: Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner.
Volume: 89
Issue: 5
Pages: 618-29
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Publication
33109609 | J:300942
First Author: Banoth B
Year: 2020
Journal: J Biol Chem
Title: ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis).
Volume: 295
Issue: 52
Pages: 18276-18283
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Publication
38479384 | J:346896
First Author: Cong J
Year: 2024
Journal: Immunity
Title: Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8(+) T cell effector functions.
Volume: 57
Issue: 4
Pages: 876-889.e11
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Publication
33691097 | J:334258
First Author: Bambouskova M
Year: 2021
Journal: Cell Rep
Title: Itaconate confers tolerance to late NLRP3 inflammasome activation.
Volume: 34
Issue: 10
Pages: 108756
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Publication
34798063 | J:317682
First Author: Howard JE
Year: 2021
Journal: Stem Cell Reports
Title: IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock.
Volume: 16
Issue: 12
Pages: 2887-2899
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Publication
36112693 | J:336811
First Author: Harapas CR
Year: 2022
Journal: Sci Immunol
Title: DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Volume: 7
Issue: 75
Pages: eabi4611
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Publication
34233954 | J:320551
 
First Author: Alphonse MP
Year: 2021
Journal: Sci Transl Med
Title: Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections.
Volume: 13
Issue: 601
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Publication
32703941 | J:293007
First Author: Batista SJ
Year: 2020
Journal: Nat Commun
Title: Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection.
Volume: 11
Issue: 1
Pages: 3687
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Publication
28410991 | J:255168
First Author: Rauch I
Year: 2017
Journal: Immunity
Title: NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.
Volume: 46
Issue: 4
Pages: 649-659
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Publication
38000038 | J:343254
First Author: Doglio MG
Year: 2023
Journal: Sci Immunol
Title: Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion.
Volume: 8
Issue: 89
Pages: eadf4404
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Publication
33097533 | J:313496
 
First Author: Qu Z
Year: 2020
Journal: Sci Adv
Title: Mycobacterial EST12 activates a RACK1-NLRP3-gasdermin D pyroptosis-IL-1β immune pathway.
Volume: 6
Issue: 43
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Publication
33077977 | J:305004
First Author: Zhou B
Year: 2020
Journal: Nat Microbiol
Title: Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling.
Volume: 5
Issue: 12
Pages: 1576-1587
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Publication
39571575 | J:359877
First Author: Wang Y
Year: 2024
Journal: Immunity
Title: A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.
Volume: 57
Issue: 12
Pages: 2737-2754.e12
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Publication
32142632 | J:323831
First Author: Zhang H
Year: 2020
Journal: Cell Host Microbe
Title: TMEM173 Drives Lethal Coagulation in Sepsis.
Volume: 27
Issue: 4
Pages: 556-570.e6
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Publication
33398185 | J:305568
First Author: Russo AJ
Year: 2021
Journal: Nat Immunol
Title: Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Volume: 22
Issue: 2
Pages: 154-165
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Publication
30962463 | J:296780
First Author: Baroja-Mazo A
Year: 2019
Journal: Sci Rep
Title: Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization.
Volume: 9
Issue: 1
Pages: 5788
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Publication
32049051 | J:288823
First Author: Zhou Y
Year: 2020
Journal: Immunity
Title: Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Volume: 52
Issue: 2
Pages: 357-373.e9
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Publication
37730693 | J:340803
First Author: Minns MS
Year: 2023
Journal: Nat Commun
Title: NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity.
Volume: 14
Issue: 1
Pages: 5832
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Publication
10322635 | J:54434
First Author: Leimeister C
Year: 1999
Journal: Dev Genet
Title: Screen for genes regulated during early kidney morphogenesis.
Volume: 24
Issue: 3-4
Pages: 273-83
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Publication
33308446 | J:325178
First Author: Xu W
Year: 2021
Journal: Cell Metab
Title: Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.
Volume: 33
Issue: 2
Pages: 424-436.e10
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Publication
30392956 | J:267416
First Author: Hara H
Year: 2018
Journal: Cell
Title: The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.
Volume: 175
Issue: 6
Pages: 1651-1664.e14
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Publication
32268091 | J:310108
First Author: Donado CA
Year: 2020
Journal: Cell Rep
Title: A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.
Volume: 31
Issue: 1
Pages: 107466
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Publication
36323258 | J:333431
First Author: Wang W
Year: 2022
Journal: Cell Rep
Title: Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Volume: 41
Issue: 5
Pages: 111582
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Publication
35705808 | J:326897
First Author: Nozaki K
Year: 2022
Journal: Nature
Title: Caspase-7 activates ASM to repair gasdermin and perforin pores.
Volume: 606
Issue: 7916
Pages: 960-967
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Publication
30485805 | J:271647
First Author: Chauhan D
Year: 2018
Journal: Cell Rep
Title: BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.
Volume: 25
Issue: 9
Pages: 2354-2368.e5
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Publication
30170814 | J:277997
First Author: Banerjee I
Year: 2018
Journal: Immunity
Title: Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Volume: 49
Issue: 3
Pages: 413-426.e5
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Publication
32234476 | J:288291
First Author: Muri J
Year: 2020
Journal: Cell Rep
Title: Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways.
Volume: 30
Issue: 13
Pages: 4399-4417.e7
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Publication
38055781 | J:355539
   
First Author: Abele TJ
Year: 2023
Journal: Elife
Title: Apoptotic signaling clears engineered Salmonella in an organ-specific manner.
Volume: 12
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Publication
33268895 | J:299968
First Author: Briard B
Year: 2020
Journal: Nature
Title: Galactosaminogalactan activates the inflammasome to provide host protection.
Volume: 588
Issue: 7839
Pages: 688-692
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Publication
30314759 | J:267873
First Author: Deng M
Year: 2018
Journal: Immunity
Title: The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.
Volume: 49
Issue: 4
Pages: 740-753.e7
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Publication
37116499 | J:335599
First Author: Bharadwaj R
Year: 2023
Journal: Immunity
Title: Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.
Volume: 56
Issue: 5
Pages: 998-1012.e8
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Publication
32193329 | J:286605
First Author: Muendlein HI
Year: 2020
Journal: Science
Title: cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.
Volume: 367
Issue: 6484
Pages: 1379-1384
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Publication
28636595 | J:243487
First Author: Zhu S
Year: 2017
Journal: Nature
Title: Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.
Volume: 546
Issue: 7660
Pages: 667-670
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Publication
33397971 | J:300952
First Author: Muendlein HI
Year: 2021
Journal: Nat Commun
Title: ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1.
Volume: 12
Issue: 1
Pages: 86
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Publication
32298652 | J:290292
First Author: Zheng M
Year: 2020
Journal: Cell
Title: Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Volume: 181
Issue: 3
Pages: 674-687.e13
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Publication
32726630 | J:300670
First Author: Kovacs SB
Year: 2020
Journal: Cell Rep
Title: Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium.
Volume: 32
Issue: 4
Pages: 107967
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Publication
32123346 | J:360216
First Author: Burke TP
Year: 2020
Journal: Nat Microbiol
Title: Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis.
Volume: 5
Issue: 5
Pages: 688-696
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Publication
30523277 | J:268081
First Author: Benmerzoug S
Year: 2018
Journal: Nat Commun
Title: STING-dependent sensing of self-DNA drives silica-induced lung inflammation.
Volume: 9
Issue: 1
Pages: 5226
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Publication
34341449 | J:359911
First Author: de Queiroz NMGP
Year: 2021
Journal: Sci Rep
Title: MyD88-dependent BCG immunotherapy reduces tumor and regulates tumor microenvironment in bladder cancer murine model.
Volume: 11
Issue: 1
Pages: 15648
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Publication
29459437 | J:258482
 
First Author: Santos JC
Year: 2018
Journal: EMBO J
Title: LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.
Volume: 37
Issue: 6
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Publication
39500322 | J:359312
First Author: Jena KK
Year: 2024
Journal: Cell
Title: Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Volume: 187
Issue: 26
Pages: 7533-7550.e23
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Publication
29176737 | J:255750
First Author: Kerur N
Year: 2018
Journal: Nat Med
Title: cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Volume: 24
Issue: 1
Pages: 50-61
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Publication
30451870 | J:267513
First Author: Saavedra PHV
Year: 2018
Journal: Nat Commun
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