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Search results 201 to 276 out of 276 for Has1

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:4427180
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422369
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EN2419; Specimen N996
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6151464
Assay Type: Immunohistochemistry
Annotation Date: 2018-04-19
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1768021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6151475
Age: embryonic day 13.0
Specimen Label: 2n
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:4427180
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422369
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EN2419; Specimen N996
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5804772
Assay Type: RNA in situ
Annotation Date: 2016-10-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3673919
Stage: TS19
Assay Id: MGI:5804787
Age: embryonic day 11.5
Specimen Label: E11.5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5804772
Assay Type: RNA in situ
Annotation Date: 2016-10-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3673920
Stage: TS20
Assay Id: MGI:5804787
Age: embryonic day 12.0
Specimen Label: E12
Detected: false
Specimen Num: 2
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Publication
9016821 | J:37703
First Author: Fülöp C
Year: 1997
Journal: Arch Biochem Biophys
Title: Coding sequence of a hyaluronan synthase homologue expressed during expansion of the mouse cumulus-oocyte complex.
Volume: 337
Issue: 2
Pages: 261-6
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Publication
20823158 | J:164205
First Author: Kobayashi N
Year: 2010
Journal: Cancer Res
Title: Hyaluronan deficiency in tumor stroma impairs macrophage trafficking and tumor neovascularization.
Volume: 70
Issue: 18
Pages: 7073-83
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Publication
36063901 | J:332016
First Author: Wang Y
Year: 2022
Journal: Am J Pathol
Title: Transforming Growth Factor-β Receptor-Mediated, p38 Mitogen-Activated Protein Kinase-Dependent Signaling Drives Enhanced Myofibroblast Differentiation during Skin Wound Healing in Mice Lacking Hyaluronan Synthases 1 and 3.
Volume: 192
Issue: 12
Pages: 1683-1698
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Publication
24790187 | J:210601
First Author: Arranz AM
Year: 2014
Journal: J Neurosci
Title: Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.
Volume: 34
Issue: 18
Pages: 6164-76
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Publication
22654110 | J:188852
First Author: Goncharova V
Year: 2012
Journal: J Biol Chem
Title: Hyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis.
Volume: 287
Issue: 30
Pages: 25419-33
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Publication
36478198 | J:331997
First Author: Lin X
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Hyaluronan Modulates the Biomechanical Properties of the Cornea.
Volume: 63
Issue: 13
Pages: 6
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Publication
30897620 | J:273385
First Author: Sun M
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.
Volume: 60
Issue: 4
Pages: 1050-1062
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Publication
30046813 | J:264401
First Author: Sun M
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Hyaluronan Regulates Eyelid and Meibomian Gland Morphogenesis.
Volume: 59
Issue: 8
Pages: 3713-3727
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Publication
9206724 | J:40792
First Author: Weigel PH
Year: 1997
Journal: J Biol Chem
Title: Hyaluronan synthases.
Volume: 272
Issue: 22
Pages: 13997-4000
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Publication
10093717 | J:53729
First Author: Spicer AP
Year: 1999
Journal: Biochem Soc Trans
Title: Mammalian hyaluronan synthases: investigation of functional relationships in vivo.
Volume: 27
Issue: 2
Pages: 109-15
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Publication
23382716 | J:195152
 
First Author: Galloway JL
Year: 2013
Journal: Front Physiol
Title: The control and importance of hyaluronan synthase expression in palatogenesis.
Volume: 4
Pages: 10
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Publication
29966020 | J:264434
First Author: Majors AK
Year: 2018
Journal: PLoS One
Title: Nitric oxide alters hyaluronan deposition by airway smooth muscle cells.
Volume: 13
Issue: 7
Pages: e0200074
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Publication
23129777 | J:309915
First Author: Lauer ME
Year: 2013
Journal: J Biol Chem
Title: Tumor necrosis factor-stimulated gene-6 (TSG-6) amplifies hyaluronan synthesis by airway smooth muscle cells.
Volume: 288
Issue: 1
Pages: 423-31
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Publication
28863216 | J:258301
First Author: Gesteira TF
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation.
Volume: 58
Issue: 11
Pages: 4407-4421
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Publication
36718364 | J:336255
First Author: Cooley A
Year: 2023
Journal: iScience
Title: Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption.
Volume: 26
Issue: 2
Pages: 105953
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Publication
25384213 | J:219524
First Author: Akgul Y
Year: 2014
Journal: J Clin Invest
Title: Hyaluronan in cervical epithelia protects against infection-mediated preterm birth.
Volume: 124
Issue: 12
Pages: 5481-9
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Publication
13782 | J:5771
First Author: Holmes RS
Year: 1976
Journal: Biochem Genet
Title: Genetics of peroxisomal enzymes in the mouse: nonlinkage of D-amino acid oxidase locus (Dao) to catalase (Cs) and L-alpha-hydroxyacid oxidase (Hao-1) loci on chromosome 2.
Volume: 14
Issue: 11-12
Pages: 981-7
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Publication
15854028 | J:97946
First Author: Tammi R
Year: 2005
Journal: J Invest Dermatol
Title: Hyaluronan synthase induction and hyaluronan accumulation in mouse epidermis following skin injury.
Volume: 124
Issue: 5
Pages: 898-905
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Publication
32623025 | J:296890
First Author: Takechi M
Year: 2020
Journal: Biochim Biophys Acta Gen Subj
Title: A pericellular hyaluronan matrix is required for the morphological maturation of cortical neurons.
Volume: 1864
Issue: 10
Pages: 129679
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Publication
36358989 | J:331418
 
First Author: Sun Y
Year: 2022
Journal: Biomolecules
Title: FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway.
Volume: 12
Issue: 11
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Publication
33454424 | J:306231
 
First Author: Nandadasa S
Year: 2021
Journal: Matrix Biol
Title: The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ hematoendothelial progenitors.
Volume: 97
Pages: 40-57
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
23788678 | -
First Author: Dembowski JA
Year: 2013
Journal: Nucleic Acids Res
Title: Has1 regulates consecutive maturation and processing steps for assembly of 60S ribosomal subunits.
Volume: 41
Issue: 16
Pages: 7889-904
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Allele
Tg(RP23-65I14)1Jno | MGI:3842797
Name: transgene insertion 1, Jeffrey L Noebels
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
15049817 | -
First Author: Emery B
Year: 2004
Journal: Mol Microbiol
Title: Has1p, a member of the DEAD-box family, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae.
Volume: 52
Issue: 1
Pages: 141-58
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Publication
28648849 | -
 
First Author: Jin H
Year: 2017
Journal: Virus Res
Title: Cellular DEAD-box RNA helicase 18 (DDX18) Promotes the PRRSV Replication via Interaction with Virus nsp2 and nsp10.
Volume: 238
Pages: 204-212
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Protein Domain
IPR044773 | DDX18/Has1_DEADc
Type: Domain
Description: This entry represents the DEAD-box helicase domain found in DDX18 from animals and Has1 from fungi. This domain contains the ATP-binding region. Has1 is a ATP-dependent RNA helicase involved in 40S and 60S ribosomal subunit biogenesis [, ]. DDX18 is a putative RNA-dependent helicase which is activated by Myc protein [].
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Genotype
Genotype
Symbol: Tg(RP23-65I14)1Jno/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Publication
19211869 | J:146431
First Author: Ernst WL
Year: 2009
Journal: J Neurosci
Title: Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy.
Volume: 29
Issue: 6
Pages: 1615-25
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Publication
10344764 | J:55099
First Author: Itano N
Year: 1999
Journal: Cancer Res
Title: Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells.
Volume: 59
Issue: 10
Pages: 2499-504
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Protein Domain
IPR028371 | HAS2
Type: Family
Description: This entry represents the hyaluronan synthase 2 (HAS2), which plays a role in hyaluronan/hyaluronic acid (HA) synthesis []. There are three different, but related hyaluronan synthases - HAS1, HAS2 and HAS3. They are multipass transmembrane enzymes, the active sites of which protrude from the inner face of the plasma membrane. HA is an unbranched disaccharide glucuronic acid/N-acetylglucosamine polymer and is one of the main components of the extracellular matrix []. High level of HA in humans is associated with cancer progression [, ]. In vertebrates, different HA polymer length can trigger different biological responses. High-molecular-mass HA represses mitogenic signalling and has anti-inflammatory properties, while low-molecular-mass HA promotes proliferation and inflammation [, ]. A study of the naked mole rat showed that HAS2 is overexpressed in naked mole rat fibroblasts, while the expression levels of HAS1 and HAS3 are similar between mouse, human and naked mole-rat cells []. HAS2 is responsible for the synthesis of the high-molecular-mass HA (HMM-HA), which triggers ECI (early contact inhibition) via the CD44 receptor and plays a key role in mediating the cancer resistance of the naked mole rat [].
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Publication
9083017 | J:39442
First Author: Spicer AP
Year: 1997
Journal: J Biol Chem
Title: Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase.
Volume: 272
Issue: 14
Pages: 8957-61
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Publication
28912382 | J:251226
First Author: Chang MY
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.
Volume: 313
Issue: 6
Pages: L1069-L1086
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Publication
23087172 | J:192627
First Author: Soh YM
Year: 2012
Journal: Endocrinology
Title: Relaxin regulates hyaluronan synthesis and aquaporins in the cervix of late pregnant mice.
Volume: 153
Issue: 12
Pages: 6054-64
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Publication
28234253 | J:355617
First Author: Li Y
Year: 2017
Journal: J Alzheimers Dis
Title: Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases.
Volume: 57
Issue: 2
Pages: 395-409
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Publication
25713331 | J:228341
 
First Author: Simon J
Year: 2015
Journal: Physiol Rep
Title: Gene expression in salivary glands: effects of diet and mouse chromosome 17 locus regulating macronutrient intake.
Volume: 3
Issue: 2
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Protein
P70312
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
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Publication
24472738 | J:209435
 
First Author: Chang MY
Year: 2014
Journal: Matrix Biol
Title: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.
Volume: 34
Pages: 1-12
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Publication
24727035 | J:215405
 
First Author: Chang MY
Year: 2014
Journal: Matrix Biol
Title: Reprint of: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.
Volume: 35
Pages: 162-73
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Protein
Q8K363
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
B2RUM8
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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